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CD4 Cells
By Afsath Jameela

CD4 Cells
Treatment centers need consulting rooms, offices, waiting rooms and secure storage for valuable drugs. They also require basic facilities to test for anemia, pregnancy, renal function, white blood cell counts and other factors that may affect treatment.
In developed countries, decisions about when to start treatment are based on the results of clinical tests called the CD4 test and the viral load test. Ideally these tests should be used everywhere, but in many parts of the world they are currently unavailable, as they require expensive equipment, electricity and trained technicians. In theory, decisions about when to start treatment may be based on symptoms alone. However in practice some treatment programmers provide medication only to people who have had a CD4 count.
There are two primary types of T-cells.
1. CD4 Cells-These cells have molecules called CD4 on its surface. These "helper" cells initiate the body's response to invading micro-organisms such as viruses.
2.CD8 Cells-These types of T-cells have a molecule called CD8 on their surface. CD8 cells destroy cells that have been infected with foreign invading micro-organisms. CD8 cells also produce antiviral substances (antibodies) that help fight off the foreign invader.
3.Normal values-In a healthy adult, a normal CD4 count can vary a great deal but is typically 600 to 1200 cells per cubic millimeter of blood
Between 600 and 350- In an HIV+ person, this range is considered "very good".
HIV medications are typically not be indicated.
Between 350 and 200-The immune system is weakened and therefore the HIV+ person may be at increased risk for infection and illness.
Function of T helper cells: Antigen presenting cells present antigen on their Class II MHC molecules. Helper T cells recognize these, with the help of their expression of CD4 co-receptor. The activation of a resting helper T cell causes it to release cytokines and other stimulatory signals. The importance of CD4 T cells is demonstrated with infection.
It has been proposed that during the non-symptomatic phase of infection, the virus has a relatively low affinity towards T cells (and has a higher affinity for macrophages), resulting in a slow kill rate of CD4+ T cells by the immune system. This is initially compensated for via the production of new helper T cells from thymus. Once the virus becomes T-tropic, it begins to infect CD4+ T cells far more efficiently, and

Counselling for Kids to be Strengthened - newindianexpress.com

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The eight people diagnosed to be mentally ill at the corporation's night shelter on Arockiasamy Road have been shifted to the United Mental Health Home in Kurumbapalayam.
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Reap health benefits from new 'squid' pill A new supplement called Bioglan Calamari Gold pill made from squid has been launched that has five times more Omega-3 than cod liver capsules and helps in improving brain and heart function. The product would help people who suffer from fatigue, memory problems and bad skin, making it the most effective way of getting your daily intake of the essential fatty acid. The one-a-day pill contains 40 per cent omega-3 DHA, which has been proven to help with heart health, brain function and high blood pressure. Studies also hailed the use of DHA that helps in improving cognitive function, lowers the risk of arthritis and postpartum depression and improves joint health. It has been made from the liver of squid and would be the first of its kind in the UK. They are available for 19.99 pounds in the market. Suzie Sawyer, nutritionist, said that Omega-3 acids are a group of essential fatty acids which can't be created by the body and DHA was the predominant omega-3 in many ...
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the immune system is overwhelmed.
At this point, functional CD4+ T cell levels begin to decrease, eventually to a point where the CD4+ T cell population is too small to recognize the full range antigens that could potentially be detected. The lack of full antigen cover results in the core symptoms of acquired immune deficiency syndrome (AIDS).CD4 T cell depletion during AIDS allows various pathogens to escape T cell recognition, thus allowing opportunistic infections that would normally elicit a helper T cell response to bypass the immune system. While these complete bypass situations only occur when the helper T cell response is absolutely necessary for infection clearance, most infections increase in severity and/or duration because the immune system's helper T cells provide a weaker contribution to a less efficient immune response.
Two components of the immune system are particularly affected in AIDS, due to its CD4+ T cell dependency:
CD8+ T cells are not stimulated as effectively during the AIDS period of infection, making AIDS patients very susceptible to most viruses, including itself. This decline in killing of CD4+ T cells results in the virus being produced for a longer period (the infected CD4+ T cells are not killed as quickly), increasing the proliferation of the virus, and accelerating the development of the disease.
Antibody class switching declines significantly once helper T cell function fails. The immune system loses its ability to improve the affinity of their antibodies, and are unable to generate B cells that can produce antibody groups such as IgG and IgA. These effects are primarily due to the loss of any helper T cell that can interact with the B lymphocyte correctly. Another symptom of AIDS is the reduction in antibody levels due to a decrease in Th2 cytokines (and less interactions by helper T cells). All of these complications result in an increased susceptibility to aggressive bacterial infections, especially in areas of the body not accessible by IgM antibodies.
If the patient does not respond to Treatment they will succumb usually to either cancers or infections; the immune system finally reaches a point where it is no longer coordinated or stimulated enough to deal with the disease.

 Keywords:  HIV,AIDS,HIV Cure,HIV Treatment,HIV Infection,HIV Dating,HIV Positive,HIV Symptoms.


Afsath Jameela is a successful lady writer from Kairo. She right now living in UK.

Breaking Open Public Places: UNFPA Launches Coolibah - 21 July 2014
MELBOURNE, Australia &ndash; At the International AIDS Conference 2014 today, UNFPA, the United Nations Population Fund, launched a youth networking zone called the coolibah, where, throughout the week, it will host a range of activities for and with young people, including a series of luncheons with leaders in the field of HIV and AIDS. (Source: UNFPA News)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
UNFPA engages young people in the fight against HIV - 21 July 2014
MELBOURNE, Australia &ndash; Every hour, about 80 young people are newly infected with HIV, according to the recently released Gap Report by UNAIDS. The participation and leadership of young people will therefore be critical in bringing the global HIV epidemic to an end. Today, at the 20th International AIDS Conference, UNFPA launched a youth networking zone called the &lsquo;coolibah&rsquo;, where young people will be able to speak with leaders in the field of HIV and AIDS. (Source: UNFPA News)
Computer?assisted reading intervention with a phonics approach for children using cochlear implants or hearing aids
The present study examined computer?assisted reading intervention with a phonics approach for deaf and hard of hearing (DHH) children in Sweden using cochlear implants or hearing aids, or a combination of both. The study included 48 children, 5, 6 and 7 years of age. Sixteen children with normal hearing (NH) served as a reference group. The first purpose of the study was to compare NH and DHH children's reading ability at pre and post?intervention. The second purpose was to investigate effects of the intervention. Cognitive and demographic factors were analyzed in relation to reading improvement. Results showed no statistically significant difference for reading ability at the group level, although NH children showed overall higher reading scores at both test points. Age comparisons r...
The RAB5?GEF Function o f RIN1 Regulates Multiple Steps During Listeria monocytogenes Infection
Abstract Listeria monocytogenes is a food?borne pathogenic bacterium that invades intestinal epithelial cells through a phagocytic pathway that relies on activation of host cell RAB5 GTPases. L. monocytogenes must subsequently inhibit RAB5, however, in order to escape lysosome?mediated destruction. Relatively little is known about upstream RAB5 regulators during L. monocytogenes entry and phagosome escape processes in epithelial cells. Here we identify RIN1, a RAS effector and RAB5?directed GEF, as a host cell factor in L. monocytogenes infection. RIN1 is rapidly engaged following L. monocytogenes infection and is required for efficient invasion of intestinal epithelial cells. RIN1?mediated RAB5 activation later facilitates the fusion of phagosomes with lysosomes, promoting clearan...
The provision of aids and adaptations, risk assessments, and incident reporting and recording procedures in relation to injury prevention for adults with intellectual disabilities: cohort study
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Wnt/?-catenin aids in regulating the proliferation of hepG2 cells mediated by thy-1.
Authors: Cheng BQ, Jiang Y, Zhu Q, Lin WG Abstract Cancer stem cells have been found to play important roles in carcinoma. Although thy-1 has been identified as a potential stem cell marker of liver cancer, whether the Wnt/?-catenin signaling pathway plays an important role in regulating hepatocarcinoma proliferation and apoptosis mediated by thy-1 remains unknown. Our results showed that high thy-1 expression caused hepG2 cells transfected with a pReceiver-M29/thy-1 eukaryotic expression vector to exhibit obvious heteromorphism, featuring double or multiple nuclei and weaker apoptosis. A high expression of ?-catenin, as a critical signaling protein of Wnt/?-catenin, and its downstream transcription factor, cyclinD1, were detected in transfected hepG2 cells. We also used aspirin...
Breaking Open Public Places: UNFPA Launches Coolibah - 21 July 2014
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UNFPA engages young people in the fight against HIV - 21 July 2014
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Hearing Aids Market Analysis by Product (Behind-The-Ear Aids,...
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Repeat Antenatal HIV Testing in the Third TrimesterRepeat Antenatal HIV Testing in the Third Trimester
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Functional assessment of multivessel coronary artery disease: ischemia-guided percutaneous coronary intervention
Invasive evaluation and treatment of coronary artery disease (CAD) has traditionally been based upon coronary angiography to determine the need for and the success of revascularization. However, coronary angiography augmented with fractional flow reserve (FFR) creates a paradigm shift, providing a more complete functional assessment of coronary lesions. Measuring FFR to identify ischemic lesions and guide revascularization results in fewer adverse outcomes, including persistent angina, myocardial infarction, and mortality. An ischemic lesion identified by FFR is more likely to lead to adverse events when compared with an angiographically similar lesion with nonischemic FFR when both are treated medically. Although the mechanism explaining this is unclear, it is likely multifactorial, inclu...<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Elizabeth Glaser Pediatric AIDS Foundation partners with Riders for Health in Malawi
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Bonga Update
Habari zenu? (How are you?) This past week in Bonga, we?ve been busier than ever. We started teaching at the government schools ¬¬? Bonga Secondary School and Bonga Primary School. We finished our curriculum at Hayatul Islamic Secondary School. Not only did we meet with each form for the last time, we also started a Peer Education club. This club is supposed to continue teaching fellow students and their local community about HIV and AIDS. We prepared them to take on this task during their orientation that consisted of making a constitution, voting for officers and doing practice teachings. When we return from break, we will watch their final teachings and hold a mini graduation ceremony. The week at Hayatul ended with our first testing day ¬? we brought a mobile testing unit to t...
The Latest from Haraa
In conclusion, there was absolutely no shortage of good times here in Haraa this week. Slowly slowly we&#8217;re becoming less mzungu, and Haraa is coming to feel more and more like home. We couldn&#8217;t feel more grateful for the chance to share with and learn from this community! Hannah B., Kelsey, Olivia, Elizabeth, and Rashidi The post The Latest from Haraa appeared first on Support For International Change. (Source: Support for International Change : HIV AIDS)
More from Team Himiti!
The Himiti team had a busy week of teaching and prepping for our village-wide testing day. We finally got to teach in our primary school, which included students and even their teachers. We thought it was important that the teachers knew about HIV/AIDS so that they can continue to educate their students after we leave. We also had the opportunity to teach in a variety of village social groups and even some random places where large groups of people were gathered and willing to listen to us. Thursday was spent entirely dedicated to prepping for our test day, the day in which any member of the village will have the opportunity to find out their HIV status through tests provided by SIC. We split up into three groups and headed to each of the sub-villages where we handed out flyers, put up pos...
Global burden, distribution, and interventions for infectious diseases of poverty
This paper aims to review the disease burden, distribution, existing interventions, and coverage for the prevention and control of IDoPs (including NTDs, malaria, TB, and HIV/AIDS), and is followed by a series of papers evaluating the effectiveness of community delivered interventions for the prevention and control of each IDoP. Image: Community based delivery of Interventions for IDoP. (Source: BioMed Central)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Antigay Laws Already Having a Negative Effect on HealthAntigay Laws Already Having a Negative Effect on Health
The criminalization of same-sex behavior around the world is having a negative effect on health in high-risk HIV groups, including men who have sex with men. Medscape Medical News (Source: Medscape Medical News Headlines)
Kenya: HIV Funding Worries in Kenya
[IRIN]Kisumu/Nairobi -The US President's Emergency Plan for Aids Relief (PEPFAR), the biggest funder of HIV programmes in Kenya, is set to significantly scale down its funding, a move activists and government officials believe could negatively affect the country's fight against the disease. (Source: AllAfrica News: HIV-Aids and STDs)
Nigeria: Ebola Virus Deadlier Than HIV/Aids - Experts
[Leadership]Ebola virus is the most difficult health challenge confronting the third world countries and is deadlier than HIV/AIDs,medical experts have declared. (Source: AllAfrica News: HIV-Aids and STDs)
Zimbabwe: Teenagers Produce HIV,Aids Film
[The Herald]Three teenagers Simbarashe Moyana, Josh Chikosha and Frankson Chikosha have embarked on an HIV and AIDS awareness campaign through a film titled "The Seed of Life" that is set to premiere next month. In an interview Moyana who is one of the producers of the film said different issues affecting the society inspired them to have the production. (Source: AllAfrica News: HIV-Aids and STDs)
Nigeria: HIV/Aids - Ogun Falls Below National Prevalence Average
[Independent]Abeokuta -The recent National HIV/AIDS Reproductive and Health Survey (NARHS) report has identified Ogun State as being below the national average of HIV infections with a prevalence rate of 0.6 per cent. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Breaking Open Public Places: UNFPA Launches Coolibah - 21 July 2014
MELBOURNE, Australia &ndash; At the International AIDS Conference 2014 today, UNFPA, the United Nations Population Fund, launched a youth networking zone called the coolibah, where, throughout the week, it will host a range of activities for and with young people, including a series of luncheons with leaders in the field of HIV and AIDS. (Source: UNFPA News)
UNFPA engages young people in the fight against HIV - 21 July 2014
MELBOURNE, Australia &ndash; Every hour, about 80 young people are newly infected with HIV, according to the recently released Gap Report by UNAIDS. The participation and leadership of young people will therefore be critical in bringing the global HIV epidemic to an end. Today, at the 20th International AIDS Conference, UNFPA launched a youth networking zone called the &lsquo;coolibah&rsquo;, where young people will be able to speak with leaders in the field of HIV and AIDS. (Source: UNFPA News)
Coreceptor Usage, Diversity, and Divergence in Drug-Naive and Drug-Exposed Individuals from Malawi, Infected with HIV-1 Subtype C for More Than 20 Years
AIDS Research and Human Retroviruses , Vol. 0, No. 0. (Source: AIDS Research and Human Retroviruses)
Erratum
Conclusion: The integrative review allowed to point important questions to be addressed in preventive actions by the health professional, including the nurse, to create a space that works with risk conditioning factors in adolescents for mental health aggravation.?Identificar los factores de riesgo asociados a los problemas de salud mental en adolescentes. Método: Se realizó una revisión integradora de artículos publicados entre los años 2007 y 2013 en cuatro bases de datos. Para la búsqueda de artículos, se utilizaron los descriptores: Salud Mental y Adolescencia, conforme a las bases DeCS/MeSH. Resultados: Se encontraron publicaciones en diferentes revistas, en distintos campos de conocimiento, siendo más frecuentes las investigaciones cuantitativas. Los problemas en salud ment...
Reliability and Reproducibility of Several Methods of Arthroscopic Assessment of Femoral Tunnel Position During Anterior Cruciate Ligament Reconstruction
To assess interobserver and intraobserver agreement of estimating anterior cruciate ligament (ACL) femoral tunnel positioning arthroscopically using circular and linear (noncircular) estimation methods and to determine whether overlay template visual aids improve agreement. (Source: Arthroscopy)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
New Tuberculosis Regimen Works Faster, Costs LessNew Tuberculosis Regimen Works Faster, Costs Less
The new once-daily oral regimen known as PaMZ appears to work on both drug-sensitive and multidrug-resistant tuberculosis. Medscape Medical News (Source: Medscape Medical News Headlines)
Digital Reading System Assists Vision Impaired to Read Graphs
People who are blind can now read more than just words, such as graphs and graphics, following the development of an affordable digital reading system by Curtin University researchers. (Source: Disabled World)
Nearly half of Albuquerque health care workers do not have a bachelor?s degree, study says
Nearly half the health care jobs in the Albuquerque metropolitan area are held by pre-baccalaureate workers, or those without a bachelor?s degree, and those workers are the fastest-growing segment of the health care industry, according to a study by the Brookings Institution. Those workers are concentrated in 10 jobs, including nurses, home health aids, medical and dental assistants and emergency medical technicians and paramedics, and many have seen large increases in earnings since 2000, Brookings? (Source: bizjournals.com Health Care:Hospitals headlines)
A Polyvalent Clade B Virus-Like Particle HIV Vaccine Combined with Partially Protective Oral Preexposure Prophylaxis Prevents Simian?Human Immunodeficiency Virus Infection in Macaques and Primes for Virus-Amplified Immunity
AIDS Research and Human Retroviruses , Vol. 0, No. 0. (Source: AIDS Research and Human Retroviruses)
Uptake and Repeat Use of Postexposure Prophylaxis in a Community-Based Clinic in Los Angeles, California
AIDS Research and Human Retroviruses , Vol. 0, No. 0. (Source: AIDS Research and Human Retroviruses)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Prevalence and Virologic Consequences of Transmitted HIV-1 Drug Resistance in Uganda
AIDS Research and Human Retroviruses , Vol. 0, No. 0. (Source: AIDS Research and Human Retroviruses)
Technology: Disrupting Disaster Response since 1881
By Dom Tolli, Preparedness, Health and Safety Services Back in 1881, the American Red Cross used the telegraph for the first time to transmit disaster information during a forest fire in Michigan. I have hunch that someone at the time probably thought the telegraph was fad and that only ?the young people? were into it. Little did anyone know it would launch the Red Cross -and the nation &#8211; onto a path of using technology to help during disasters. Since 1881, the Red Cross has made a paradigm shift in how it distributes information to the public in times of crisis. Instead of distributing millions of brochures and flyers with emergency we now issue millions of mobile alerts and our apps have more than 100 million mobile views. Now, mobile technology is bringing the White House, th...
Study: iPad-based HIV prevention game increased adolescents? knowledge of the disease
Children who played iPad-based HIV prevention game PlayForward: Elm City Stories knew more about HIV risk than those that played other video games, according to an oral abstract on a randomized control trial of 198 adolescents presented at the AIDS conference this week. The mean age of children in this trial was 13. The NIH-funded video game was developed [&#8230;] (Source: mobihealthnews)
Africa: Heightened HIV Risk for People With Disabilities
[IRIN]Melbourne -Inaccessible health services for people with disabilities (PWD), combined with social stigma and violence, contribute to high HIV risk - a gap that must be filled if the disabled are not to remain disproportionately vulnerable to HIV/AIDS, say health experts and activists. (Source: AllAfrica News: HIV-Aids and STDs)
Kenya: BD & PEPFAR Launch Multi-Year Labs for Life Initiative in Kenya
[U.S. Embassy Nairobi]Nairobi, Kenya -Program Focuses on Strengthening Healthcare Systems, Starting with Accreditation for 10 Laboratories (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Breaking Open Public Places: UNFPA Launches Coolibah - 21 July 2014
MELBOURNE, Australia &ndash; At the International AIDS Conference 2014 today, UNFPA, the United Nations Population Fund, launched a youth networking zone called the coolibah, where, throughout the week, it will host a range of activities for and with young people, including a series of luncheons with leaders in the field of HIV and AIDS. (Source: UNFPA News)
UNFPA engages young people in the fight against HIV - 21 July 2014
MELBOURNE, Australia &ndash; Every hour, about 80 young people are newly infected with HIV, according to the recently released Gap Report by UNAIDS. The participation and leadership of young people will therefore be critical in bringing the global HIV epidemic to an end. Today, at the 20th International AIDS Conference, UNFPA launched a youth networking zone called the &lsquo;coolibah&rsquo;, where young people will be able to speak with leaders in the field of HIV and AIDS. (Source: UNFPA News)
Zimbabwe: HIV Status Does Not Affect Eligibility for Pension
[The Herald]Can an HIV positive person qualify for a pension? This was a questioned that was asked by one correspondent who claims to have contributed to the NSSA national pension scheme from 1994 to 2007. (Source: AllAfrica News: HIV-Aids and STDs)
Southern Africa: HIV and Aids Threat to SADC Development
[The Herald]AS leaders from the region gather for the 34th Sadc Summit in Victoria Falls next month, they must seriously reflect on the devastating effect of the HIV and Aids pandemic that is threatening to decimate entire populations. (Source: AllAfrica News: HIV-Aids and STDs)
Rwanda: Circumcision Yields Results as Ebola Threatens
[New Times]A new study by the University of Illinois indicates that circumcised men do not only lower chances of getting HIV by 60% but also are less likely to engage in unprotected sex. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Nigeria: HIV Infection No Longer On the Rise in Nigeria - Idoko
[Leadership]The fear of HIV/AIDS, that debilitating disease, remains the beginning of wisdom for everyone. A recent report that HIV infection was on the increase in the country was not well received. But in this interview with WINIFRED OGBEBO, the director-general, National Agency for the Control of AIDS (NACA), Prof. John Idoko debunks such claim, while giving reports of the activities of the agency (Source: AllAfrica News: HIV-Aids and STDs)
South Africa: Sex Workers Demand Representation On District Aids Council
[Health-e]Sex workers are asking for representation on the Northern Cape's John Taolo Gaetsewe District AIDS Council as sex work soars in local mining community. (Source: AllAfrica News: Health and Medicine)
New partnership to improve access to essential pain medications for people living with HIV
(Elizabeth Glaser Pediatric AIDS Foundation) Today the Elizabeth Glaser Pediatric AIDS Foundation and the American Cancer Society announced a new partnership to improve access to essential pain medications for people living with HIV in Swaziland. As part of ACS' Treat the Pain initiative, this new partnership will help improve efforts to better integrate pain management into HIV/AIDS services throughout the country. (Source: EurekAlert! - Cancer)
Do Decision Aids Help Patients Make Difficult Choices? (CME/CE)
(MedPage Today) -- Decision aids designed to help patients make general healthcare choices, such as selecting a treatment location, provide some help, but condition-specific aids may provide the most useful information for patients and families. (Source: MedPage Today Cardiovascular)
Sticking to minimum standards: implementing antibiotic stewardship in intensive care
ConclusionA systematic approach to quality improvement combined with the implementation of a tailored, multi?faceted intervention can improve antimicrobial prescribing practices. (Source: Internal Medicine Journal)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Charakteristika und Koinfektionen mit Syphilis bei neu mit HIV diagnostizierten Patienten aus dem Universitätsklinikum Dresden von 1987?2012
Zusammenfassung HintergrundKoinfektionsraten von HIV und Syphilis sind über Meldedaten nicht erhältlich und es existiert in Ostdeutschland bisher kein Kollektiv, an dem dies repräsentativ für eine Region ermittelt wurde. Steigende Syphilis?Inzidenzraten 2010?2012 besonders bei Männern mit sexuellen Kontakten zu Männern (MSM) werden als Mitursache für die in dieser Gruppe aktuell wieder steigenden HIV?Neuinfektionsraten diskutiert. Patienten und MethodikDie Charakteristika von 355 konsekutiven, neu mit HIV diagnostizierten Patienten aus dem Universitätsklinikum Dresden von 1987?2012 wurden retrospektiv anhand der Meldedaten für den Dresdner Raum und im Vergleich zu bundesweiten Daten überprüft sowie Koinfektionen mit Syphilis analysiert. ErgebnisseIn unserem Kollektiv fan...
HCV RNA viral load is independent from CD4 cell count and plasma HIV RNA viral load in immunocompetent HIV-HCV co-infected patients: a 3-years follow-up study
Conclusions: The HCV RNA load, a known pretreatment predictor of response to antiviral therapy, was independent of the two main parameters of HIV disease, plasma HIV RNA and CD4 cell count, over an observation time of 3 years in patients with recovered or spontaneously maintained immunocompetence. (Source: AIDS Research and Therapy)
Decision Aids for Advance Care Planning: An Overview of the State of the Science.
Authors: Butler M, Ratner E, McCreedy E, Shippee N, Kane RL Abstract Advance care planning honors patients' goals and preferences for future care by creating a plan for when illness or injury impedes the ability to think or communicate about health decisions. Fewer than 50% of severely or terminally ill patients have an advance directive in their medical record, and physicians are accurate only about 65% of the time when predicting patient preferences for intensive care. Decision aids can support the advance care planning process by providing a structured approach to informing patients about care options and prompting them to document and communicate their preferences. This review, commissioned as a technical brief by the Agency for Healthcare Research and Quality Effective Health ...
Pain anxiety and negative outcome expectations for activity: Negative psychological profiles differ between the inactive and active
Conclusion: Identifying differences in negative psychological factors aids in the understanding of differential adherence between activity groups and highlights possible factors to change in future intervention research. © 2014 American College of Rheumatology. (Source: Arthritis Care and Research)
Breaking Open Public Places: UNFPA Launches Coolibah - 21 July 2014
MELBOURNE, Australia &ndash; At the International AIDS Conference 2014 today, UNFPA, the United Nations Population Fund, launched a youth networking zone called the coolibah, where, throughout the week, it will host a range of activities for and with young people, including a series of luncheons with leaders in the field of HIV and AIDS. (Source: UNFPA News)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
UNFPA engages young people in the fight against HIV - 21 July 2014
MELBOURNE, Australia &ndash; Every hour, about 80 young people are newly infected with HIV, according to the recently released Gap Report by UNAIDS. The participation and leadership of young people will therefore be critical in bringing the global HIV epidemic to an end. Today, at the 20th International AIDS Conference, UNFPA launched a youth networking zone called the &lsquo;coolibah&rsquo;, where young people will be able to speak with leaders in the field of HIV and AIDS. (Source: UNFPA News)
Cerebral microsporidiosis manifesting as progressive multifocal leukoencephalopathy in an HIV-infected individual - a case report.
This report underscores the need for physicians to consider microsporidiosis (potentially affecting the brain) when no other etiology is established both in HIV, non-HIV immunosuppressed patients and in immunocompetent individuals. PMID: 25057277 [PubMed] (Source: AIDS Research and Therapy)
Holla from Njeku!
Njeku, a small but beautiful village nestled in a valley at the base of Sakila Mountain. While our time here has been short, the past week has shown great promise for our impact to be anything but small. The village leaders have been helpful, and it seems that most of the people we come across now recognize us as more than just those new visitors in town. As always, Sunday is a great day for worship, and we used this to our advantage. Understanding our mission, the VEO (Village Executive Officer) kindly sent out letters to the various village churches so that they would mention our testing day during their announcements section of their service. The church we have attended for the past two weeks once again welcomed us with open arms. More than others, it seems they have truly accepted us i...
Mambo from the Sakila crew!
This week we finally started teaching in schools, which has been absolutely incredible. We finally feel like we?re doing what we set out to do. In Sakila, we have two primary schools and two secondary schools, and each teaching has been accompanied by unique challenges. We?ll cover a few of the most interesting occurrences here. Our first teaching was Wednesday (July 9th) afternoon at Sakila Secondary School. When we talked to the headmaster, we were told there would be between 50 and 70 students in each Form (grade), but when we showed up, many students had yet to pay their school fees and we ended up teaching classes of 15. This meant we taught our most important lesson to less than half of the student body, which was disappointing. Regardless, this worked as a good trial run to work...
Early Antiretrovirals Shrink HIV Reservoir in NewbornsEarly Antiretrovirals Shrink HIV Reservoir in Newborns
Evidence continues to support starting antiretrovirals immediately after birth to reduce HIV reservoir size and suppress the virus over the long term. Medscape Medical News (Source: Medscape Medical News Headlines)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Ghana: Rape Victim Demands HIV Test of Doctor
[Ghanaian Chronicle]The Tema Regional office of the Domestic Violence and Victim Support Unit (DOVVSU), is investigating a medical doctor for allegedly raping a 22-year-old student. (Source: AllAfrica News: HIV-Aids and STDs)
Breaking Open Public Places: UNFPA Launches Coolibah - 21 July 2014
MELBOURNE, Australia &ndash; At the International AIDS Conference 2014 today, UNFPA, the United Nations Population Fund, launched a youth networking zone called the coolibah, where, throughout the week, it will host a range of activities for and with young people, including a series of luncheons with leaders in the field of HIV and AIDS. (Source: UNFPA News)
UNFPA engages young people in the fight against HIV - 21 July 2014
MELBOURNE, Australia &ndash; Every hour, about 80 young people are newly infected with HIV, according to the recently released Gap Report by UNAIDS. The participation and leadership of young people will therefore be critical in bringing the global HIV epidemic to an end. Today, at the 20th International AIDS Conference, UNFPA launched a youth networking zone called the &lsquo;coolibah&rsquo;, where young people will be able to speak with leaders in the field of HIV and AIDS. (Source: UNFPA News)
Nigeria: Report Scores Nigeria Low on HIV/Aids Control
[Guardian]CHUKWUMA MUANYA writes on a new global report which points to slow progress in the fight against HIV/AIDS in Nigeria (Source: AllAfrica News: HIV-Aids and STDs)
Africa: Clinton Says Aids-Free Generation 'Within Reach'
[AlertNet]Melbourne -An AIDS-free generation is within reach if early treatment is provided to people infected with HIV and help scaled up for women and children, former U.S. president Bill Clinton said on Wednesday. (Source: AllAfrica News: Health and Medicine)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Kenya: Circumcised Men Not Using Condoms
[The Star]Most men are likely to engage in unprotected sex after being circumcised. A study presented at the 20th International Aids conference indicated that circumcised men don't use condoms owing to the perception that they are at a lower risk of getting HIV. (Source: AllAfrica News: HIV-Aids and STDs)
Routine HIV Screening in New York City and New OrleansRoutine HIV Screening in New York City and New Orleans
This report describes novel HIV screening programs at two urban health care settings, one in New York City and one in New Orleans. Might they serve as models that could be adapted by other facilities? Morbidity & Mortality Weekly Report (Source: Medscape Today Headlines)
Locomotor Functions Over Time in HIV-Infected PatientsLocomotor Functions Over Time in HIV-Infected Patients
How does motor function over time in HIV+ individuals compare with healthy individuals? AIDS (Source: Medscape Today Headlines)
Hoped-for 'AIDS cure' drug fails miserably in monkey experiments; HIV outwits Big Pharma yet again
(NaturalNews) A monkey version of the HIV virus can outwit anti-AIDS drugs just days after entering the body, according to researchers who were disappointed that Big Pharma still cannot produce a human cure for the disease.If the same thing is true for humans, treatment for HIV... (Source: NaturalNews.com)
Kenya: Organization Wants Prostitution Legalized.
[The Star]Sex workers want prostitution legalized so that the country benefits from donor funding. Activist Peninah Mwangi says the government can in turn use the money to carry out HIV/AIDS sensitization campaigns, purchase ARVs and carry out empowerment programmes for sex workers. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Featured in NEJM Journal Watch: Really Rapid Review ? AIDS 2014, Melbourne (FREE)
By the NEJM Journal Watch Editors In his blog HIV and ID Observations, ? (Source: Physician's First Watch current issue)
Breaking Open Public Places: UNFPA Launches Coolibah - 21 July 2014
MELBOURNE, Australia &ndash; At the International AIDS Conference 2014 today, UNFPA, the United Nations Population Fund, launched a youth networking zone called the coolibah, where, throughout the week, it will host a range of activities for and with young people, including a series of luncheons with leaders in the field of HIV and AIDS. (Source: UNFPA News)
UNFPA engages young people in the fight against HIV - 21 July 2014
MELBOURNE, Australia &ndash; Every hour, about 80 young people are newly infected with HIV, according to the recently released Gap Report by UNAIDS. The participation and leadership of young people will therefore be critical in bringing the global HIV epidemic to an end. Today, at the 20th International AIDS Conference, UNFPA launched a youth networking zone called the &lsquo;coolibah&rsquo;, where young people will be able to speak with leaders in the field of HIV and AIDS. (Source: UNFPA News)
Breaking Open Public Places: UNFPA Launches Coolibah - 21 July 2014
MELBOURNE, Australia &ndash; At the International AIDS Conference 2014 today, UNFPA, the United Nations Population Fund, launched a youth networking zone called the coolibah, where, throughout the week, it will host a range of activities for and with young people, including a series of luncheons with leaders in the field of HIV and AIDS. (Source: UNFPA News)
UNFPA engages young people in the fight against HIV - 21 July 2014
MELBOURNE, Australia &ndash; Every hour, about 80 young people are newly infected with HIV, according to the recently released Gap Report by UNAIDS. The participation and leadership of young people will therefore be critical in bringing the global HIV epidemic to an end. Today, at the 20th International AIDS Conference, UNFPA launched a youth networking zone called the &lsquo;coolibah&rsquo;, where young people will be able to speak with leaders in the field of HIV and AIDS. (Source: UNFPA News)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
This won't be the AIDS-free generation
He was just 18 years old when he got the news. It was the summer before his senior year in high school. Bryan Seth Johnson was diagnosed with the human immunodeficiency virus, better known as HIV. (Source: WDSU.com - Health)
Breaking Open Public Places: UNFPA Launches Coolibah - 21 July 2014
MELBOURNE, Australia &ndash; At the International AIDS Conference 2014 today, UNFPA, the United Nations Population Fund, launched a youth networking zone called the coolibah, where, throughout the week, it will host a range of activities for and with young people, including a series of luncheons with leaders in the field of HIV and AIDS. (Source: UNFPA News)
UNFPA engages young people in the fight against HIV - 21 July 2014
MELBOURNE, Australia &ndash; Every hour, about 80 young people are newly infected with HIV, according to the recently released Gap Report by UNAIDS. The participation and leadership of young people will therefore be critical in bringing the global HIV epidemic to an end. Today, at the 20th International AIDS Conference, UNFPA launched a youth networking zone called the &lsquo;coolibah&rsquo;, where young people will be able to speak with leaders in the field of HIV and AIDS. (Source: UNFPA News)
Mesenteric masses: Approach to differential diagnosis at MRI with histopathologic correlation
Magnetic resonance imaging (MRI) is an outstanding tool for the identification and characterization of mesenteric masses. Mesenteric masses may be solid or cystic. Most solid mesenteric masses are neoplastic, with sclerosing mesenteritis a notable exception. Entirely cystic mesenteric masses are typically benign. The excellent soft?tissue contrast afforded by MRI aids in narrowing the differential diagnosis of mesenteric masses. Accurately characterizing both solid and cystic mesenteric masses is important, as management ranges from active surveillance to medical management to surgical resection, depending on the tissue composition of the mass. An MRI?based approach to the differential diagnosis of mesenteric masses is presented.J. Magn. Reson. Imaging 2014. © 2014 Wiley Periodicals, ...
Oral Hepatitis C Drugs Helping Patients Coinfected With HIVOral Hepatitis C Drugs Helping Patients Coinfected With HIV
Results from TURQUOISE-1 and PHOTON-2 show that interferon-free regimens are achieving impressive response rates with few adverse events in patients coinfected with hep C and HIV. Medscape Medical News (Source: Medscape Gastroenterology Headlines)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Nigeria: Nigeria Doctors' Strike Threatens HIV/Aids Care
[VOA]Nearly a month into a nationwide doctor's strike, HIV/AIDS patients in some parts of northern Nigeria say health care is rapidly declining, and they have become largely dependent upon foreign aid organizations. Doctors say the strike is the only way they know to rescue Nigeria's flailing healthcare system, but nurses accuse strikers of abandoning public care in favor of more lucrative private practices. (Source: AllAfrica News: HIV-Aids and STDs)
Africa: Aids Conference Mourns the Dead, Debates Setbacks
[IPS]Melbourne -The 20th International AIDS Conference concluded today as the first in its history that remembered not just the 39 million people worldwide who have died of AIDS but also those who lost their lives in the crashed MH17 flight carrying six of its delegates, one of whom was the past president of the International AIDS Society (IAS). (Source: AllAfrica News: HIV-Aids and STDs)
[World Report] MH17 tragedy: HIV community mourns loss of colleagues
Organisers of this year's International AIDS Conference dedicated the meeting to the delegates who were killed on ill-fated flight MH17. Udani Samarasekera reports. (Source: LANCET)
Humanized PA14 (a monoclonal CCR5 antibody) for treatment of people with HIV infection.
CONCLUSIONS: Limited evidence from three small trials suggests that PRO 140 might demonstrate potent, short-term, dose-dependent, highly significant antiviral activity. However, as the evidence is insufficient, recommendations cannot yet be made. Larger, longer-term, double-blind RCTs are required to provide conclusive evidence. PMID: 25063928 [PubMed - as supplied by publisher] (Source: Cochrane Database of Systematic Reviews)
Breaking Open Public Places: UNFPA Launches Coolibah - 21 July 2014
MELBOURNE, Australia &ndash; At the International AIDS Conference 2014 today, UNFPA, the United Nations Population Fund, launched a youth networking zone called the coolibah, where, throughout the week, it will host a range of activities for and with young people, including a series of luncheons with leaders in the field of HIV and AIDS. (Source: UNFPA News)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
UNFPA engages young people in the fight against HIV - 21 July 2014
MELBOURNE, Australia &ndash; Every hour, about 80 young people are newly infected with HIV, according to the recently released Gap Report by UNAIDS. The participation and leadership of young people will therefore be critical in bringing the global HIV epidemic to an end. Today, at the 20th International AIDS Conference, UNFPA launched a youth networking zone called the &lsquo;coolibah&rsquo;, where young people will be able to speak with leaders in the field of HIV and AIDS. (Source: UNFPA News)
Suicidal ideation among attendees of a West African HIV clinic - Ogundipe OA, Olagunju AT, Adeyemi JD.
This study was set to determine the prevalence of suicidal ideation and the associated risk factors among PLWHA.... (Source: SafetyLit: All (Unduplicated))
Risk factors associated with mental health issues in adolescents: a integrative review
Conclusion: The integrative review allowed to point important questions to be addressed in preventive actions by the health professional, including the nurse, to create a space that works with risk conditioning factors in adolescents for mental health aggravation.?Identificar los factores de riesgo asociados a los problemas de salud mental en adolescentes. Método: Se realizó una revisión integradora de artículos publicados entre los años 2007 y 2013 en cuatro bases de datos. Para la búsqueda de artículos, se utilizaron los descriptores: Salud Mental y Adolescencia, conforme a las bases DeCS/MeSH. Resultados: Se encontraron publicaciones en diferentes revistas, en distintos campos de conocimiento, siendo más frecuentes las investigaciones cuantitativas. Los problemas en salud ment...
Errata
Conclusion: The integrative review allowed to point important questions to be addressed in preventive actions by the health professional, including the nurse, to create a space that works with risk conditioning factors in adolescents for mental health aggravation.?Identificar los factores de riesgo asociados a los problemas de salud mental en adolescentes. Método: Se realizó una revisión integradora de artículos publicados entre los años 2007 y 2013 en cuatro bases de datos. Para la búsqueda de artículos, se utilizaron los descriptores: Salud Mental y Adolescencia, conforme a las bases DeCS/MeSH. Resultados: Se encontraron publicaciones en diferentes revistas, en distintos campos de conocimiento, siendo más frecuentes las investigaciones cuantitativas. Los problemas en salud ment...
This Week: AIDS Progress, Vegan Diet
(MedPage Today) -- Delegates to the IAC step up the pace, a top doctor's decision to go vegan, and disappointing results for robotic surgery topped this week's news at MedPage Today. (Source: MedPage Today Pediatrics)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Staying Sane as Medicine Goes CrazyStaying Sane as Medicine Goes Crazy
Technological advances, greater demands from patients and insurers, and a host of other stressors are pushing doctors to the brink. Despairing as it may sound, there are ways to regain control. Medscape Business of Medicine (Source: Medscape Hiv-Aids Headlines)
HIV Cure Still Years Away (CME/CE)
(MedPage Today) -- MELBOURNE, Australia -- The word "cure" is back in the HIV/AIDS vocabulary but the research is just out of the starting gate. (Source: MedPage Today Infectious Disease)
Controversy over ban on gay men donating blood
A lot has changed since the U.S. banned gay men from donating blood at the height of the AIDS scare in the 1980s; why is the policy still in place? (Source: Health News: CBSNews.com)
This won't be the AIDS-free generation
In the United States, 26% of all new HIV infections are among young people ages 13 to 24. Yet only 1 in 5 high school students is tested for HIV. (Source: CNN.com - Health)
More Positive Stories Needed: HIV in Countries with Low ARV Therapy Coverage
  By Cecilia Ferreyra, MSF HIV & TB Technical Advisor More than 24 million people living with HIV; 9 million people on antiretroviral treatment (ART); 1.5 million new infections; 1.1 million deaths from AIDS-related causes. These are some of the data just released by UNAIDS on HIV/AIDS in sub-Saharan Africa in 2013, by far the area of ??the world hardest-hit by the virus. But, in this broad area covering nearly the entire continent, we see very different realities. (Source: MSF News)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Kenya: We Need a New Strategy to Fight HIV in Nyanza
[The Star]The Kenya HIV Prevention Revolution Road Map gives the glaring disparities in the number of HIV infections in all the 47 counties. Nairobi tops the list with close to 1.8 million HIV-positive people followed by all the counties in Nyanza except Nyamira. (Source: AllAfrica News: HIV-Aids and STDs)
Kenya: Group's Pledge to Fight HIV
[The Star]AN International HIV campaign programme has pledged to partner with the Homa Bay county government to reduce the spread of the disease. (Source: AllAfrica News: HIV-Aids and STDs)
Kenya: Young Men Report Having Several Sex Partners
[The Star]Young men between 15 and 24 years are sexually active and have multiple partners. A HIV report by the health ministry also reveals that a majority of women start having sex when they are 17 years. The report recommends behavioral change and condom use promotion. (Source: AllAfrica News: HIV-Aids and STDs)
Africa: HIV/Aids - More Positive Stories Needed
[MSF]As HIV & TB Technical Advisor for Médecins Sans Frontières (MSF), I have just returned from South Sudan, where I visited our project in Yambio, in Western Equatorial state. MSF supports the national HIV/AIDS programme there, with a special focus on pregnant women and children under five years of age. In general, the situation in South Sudan is the reality of many countries in West and Central Africa, where assistance to HIV-positive people is ineffective or nonexistent; and where conflict (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Lift U.S. Ban on Blood Donations by Gay Men, Experts Say
American Red Cross, other groups also urge easing restrictions due to better blood screening (Source: Fertility News - Doctors Lounge)
Kenya: More Funding Needed for TB-HIV Co-Infection
[Key Correspondents]HIV and tuberculosis advocates say failure by donors and governments to invest more in these diseases may thwart efforts to end both epidemics resulting in thousands of preventable deaths. (Source: AllAfrica News: HIV-Aids and STDs)
Africa: Young People Must Play Leading Role in HIV Advocacy
[Key Correspondents]Delegates at the AIDS 2014 conference (20-25 July) are recognising that young people are the future and it is vital to empower them to take a leading role in the response to HIV. (Source: AllAfrica News: HIV-Aids and STDs)
Africa: Post 2015 Development Agenda and HIV - the Epidemic's Way Forward
[Key Correspondents]The end of AIDS has to be at the centre of the post-2015 development agenda to ensure the holistic, socio-economic development of communities around the world. (Source: AllAfrica News: HIV-Aids and STDs)
Africa: Young People Speak Out Against Stigma of Youth Condom Use
[Key Correspondents]Young people around the world are not receiving clear messages or support to use condoms to prevent HIV infection, according to delegates at the AIDS 2014 conference in Melbourne, Australia (20-25 July). (Source: AllAfrica News: Health and Medicine)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Africa: HIV Eradication Remains Challenging Milestone for Scientists
[Key Correspondents]"How come we have been able to fit everything that life needs into one mobile phone device we can keep in our pockets, but cannot find the cure for HIV?" This was a question a young man asked Dr Francoise Barre-Sinnousi, the International AIDS Society chief executive, in a discussion at the AIDS 2014 conference in Melbourne, Australia. (Source: AllAfrica News: Health and Medicine)
Africa: At Aids Conference, Prevention Pill Stirs Excitement
[VOA]Participants in this year's International AIDS Conference welcomed progress on a new pill that may prevent transmission of the deadly HIV virus - one of the advances that have provoked celebrations as well as debates. (Source: AllAfrica News: Health and Medicine)
Number of new HIV infection has decreased by 57%: Harsh Vardhan
Govt's objective was to reduce new infections further by 50% and provide comprehensive care and support to all persons living with HIV and AIDS. (Source: The Economic Times)
Breaking Open Public Places: UNFPA Launches Coolibah - 21 July 2014
MELBOURNE, Australia &ndash; At the International AIDS Conference 2014 today, UNFPA, the United Nations Population Fund, launched a youth networking zone called the coolibah, where, throughout the week, it will host a range of activities for and with young people, including a series of luncheons with leaders in the field of HIV and AIDS. (Source: UNFPA News)
UNFPA engages young people in the fight against HIV - 21 July 2014
MELBOURNE, Australia &ndash; Every hour, about 80 young people are newly infected with HIV, according to the recently released Gap Report by UNAIDS. The participation and leadership of young people will therefore be critical in bringing the global HIV epidemic to an end. Today, at the 20th International AIDS Conference, UNFPA launched a youth networking zone called the &lsquo;coolibah&rsquo;, where young people will be able to speak with leaders in the field of HIV and AIDS. (Source: UNFPA News)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Africa: Police Must Play Role in Preventing HIV Among Criminalised Groups
[Key Correspondents]Delegates at the 20th International AIDS conference are tackling the issue of law enforcement policies and practices that often undermine the efforts of public health officials to reduce HIV transmission. (Source: AllAfrica News: HIV-Aids and STDs)
Kenya: HIV Related Complications Killed 58 Thousand Kenyans Last Year
[The Star]More than 58 thousand people died due to HIV related complications last year. A report by health ministry shows that the number of deaths of women were at 27,000, men at about 21,000 and children at 10,000. (Source: AllAfrica News: HIV-Aids and STDs)
Diagnostic role of ultrasound and elastosonography in nodular goiter.
Authors: Rago T, Vitti P Abstract Among several ultrasound patterns, thyroid nodule hypoechogenicity, spot microcalcifications, and an absent halo sign are used for predicting increased risk of thyroid malignancy. The predictive value of ultrasound, however, increases at the expense of its sensitivity, and malignancy is predicted with high specificity only when multiple ultrasound features are simultaneously present. Ultrasound features are important in determining the strength of the indication for carrying out fine needle aspiration. To this end, a system for standardization of ultrasound features (Thyroid Imaging Reporting and Data System) aids in establishing risk of malignancy. Ultrasound elastosonography is a technique that assesses hardness as an indicator of malignancy risk...
New licensing agreement could improve treatment options for children living with HIV
(Elizabeth Glaser Pediatric AIDS Foundation) The Elizabeth Glaser Pediatric AIDS Foundation applauds the new licensing agreement between the Medicines Patent Pool and Gilead Sciences, Inc. to improve access to tenofovir alafenamide fumarate, a promising new HIV medication. The agreement was announced during the 20th International AIDS Conference in Melbourne, Australia. While tenofovir alafenamide fumarate is still in Phase III clinical trials, early data suggests it could be a key ingredient in the next generation of first-line fixed-dose treatment options for children living with HIV. (Source: EurekAlert! - Infectious and Emerging Diseases)
Commissioning of hearing aids: response to Hearing Link?s campaign
The campaign, organised by Hearing Link, was called ?Stop the cuts to hearing aid services?. (Source: NHS Networks)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Maternal and health care workers' perceptions of the effects of exclusive breastfeeding by HIV positive mothers on maternal and infant health in Blantyre, Malawi
Conclusion: While most participants considered exclusive breastfeeding as an important component of the wellbeing of their infants' health, they did not share the worldwide acknowledged benefits of exclusive breastfeeding in the prevention of mother-to-child transmission (PMTCT) of HIV. These results suggest a need for more breastfeeding education for all mothers, communities and nurse-midwives involved in breastfeeding counseling in the context of HIV infection. Maternal wellbeing promotion activities such as nutrition supplementation need to be included in all PMTCT of HIV programs. (Source: BMC Pregnancy and Childbirth - Latest articles)
Progress toward prevention of transfusion-transmitted hepatitis B and hepatitis C infection - sub-saharan Africa, 2000-2011.
This report summarizes HBV- and HCV-related surveillance data reported by the blood transfusion services of WHO member states to WHO's Global Database on Blood Safety (GDBS) (4). It also evaluates the performance of blood safety programs in screening for HBV and HCV in 38 sub-Saharan Africa countries.* Selected GDBS indicators were compared for the years 2000 and 2004 (referred to as the 2000/2004 period) and 2010 and 2011 (referred to as the 2010/2011 period). From 2000/2004 to 2010/2011, the median of the annual number of units donated per country increased, the number of countries screening at least 95% of blood donations for HBV and HCV increased, and the median of the national prevalence of HBV and HCV marker-reactive blood donations decreased. These findings suggest that during the p...
Cancer Treatment Disparities in HIV-Infected Individuals in the United States [AIDS-Related Cancer]
Conclusion HIV-infected individuals are less likely to receive treatment for some cancers than uninfected people, which may affect survival rates. (Source: Journal of Clinical Oncology)
Glucose-6-phosphate dehydrogenase plays a critical role in hypoxia-induced CD133+ progenitor cells self-renewal...
Authors: Chettimada S, Joshi SR, Al Zoubi A, Gebb SA, McMurtry IF, Gupte RS, Gupte SA Abstract Although hypoxia is detrimental to most cell types, it aids survival of progenitor cells and is associated with diseases like cancer and pulmonary hypertension in humans. Here we demonstrate that the proliferation and growth of human CD133(+) progenitor cells, which contribute to tumorigenesis and the development of pulmonary hypertension, are increased when cultured under hypoxic conditions. Furthermore, glucose-6-phosphate dehydrogenase (G6PD) activity was increased 3-fold in hypoxic CD133(+) cells. The increased G6PD activity was required for CD133(+) cell proliferation, and their growth was arrested by G6PD inhibition or knockdown. G6PD activity upregulated expression of HIF1?, cycli...
Maternal and health care workers¿ perceptions of the effects of exclusive breastfeeding by HIV positive mothers on maternal and infant health in Blantyre, Malawi
Conclusion: While most participants considered exclusive breastfeeding as an important component of the wellbeing of their infants? health, they did not share the worldwide acknowledged benefits of exclusive breastfeeding in the prevention of mother-to-child transmission (PMTCT) of HIV. These results suggest a need for more breastfeeding education for all mothers, communities and nurse-midwives involved in breastfeeding counseling in the context of HIV infection. Maternal wellbeing promotion activities such as nutrition supplementation need to be included in all PMTCT of HIV programs. (Source: BMC Pregnancy and Childbirth - Latest articles)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Developing Fly-Inspired, Piezoelectric Hearing Aids
Using a fly as inspiration, researchers at the University of Texas at Austin (UT) have created a miniature device that they say could lead to the development of hypersensitive hearing aids.Theresearchteam focused on theOrmia ochraceafly, which has a highly sophisticated hearing system. Contrary to other animals, insects generally cannot pinpoint sound sources because sound waves essentially hit both of their ears at the same time. TheOrmia ochraceafly&rsquo;s hearing system is different, as it contains tiny, teeter-totter-like mechanisms within the ear system that enable the fly to pinpoint sound sources within two degrees. (Source: Medical Design Online News)
Breaking Open Public Places: UNFPA Launches Coolibah - 21 July 2014
MELBOURNE, Australia &ndash; At the International AIDS Conference 2014 today, UNFPA, the United Nations Population Fund, launched a youth networking zone called the coolibah, where, throughout the week, it will host a range of activities for and with young people, including a series of luncheons with leaders in the field of HIV and AIDS. (Source: UNFPA News)
UNFPA engages young people in the fight against HIV - 21 July 2014
MELBOURNE, Australia &ndash; Every hour, about 80 young people are newly infected with HIV, according to the recently released Gap Report by UNAIDS. The participation and leadership of young people will therefore be critical in bringing the global HIV epidemic to an end. Today, at the 20th International AIDS Conference, UNFPA launched a youth networking zone called the &lsquo;coolibah&rsquo;, where young people will be able to speak with leaders in the field of HIV and AIDS. (Source: UNFPA News)
Cancer Drug First to Wake Dormant HIVCancer Drug First to Wake Dormant HIV
An HDAC inhibitor used to treat cancer drives enough concealed HIV out of hiding for the virus to be detected on standard testing, report researchers. Medscape Medical News (Source: Medscape Medical News Headlines)
Integrated Guidance for Developing Epidemiologic Profiles
This guidance has been developed by the Centers for Disease Control and Prevention (CDC) and the Health Resources and Services Administration (HRSA) to assist persons who compile and interpret HIV prevention and care data for state, territorial, or local HIV epidemiologic profiles. (Source: CDC HIV/AIDS Prevention)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Bacteria in Semen May Affect HIV Transmission, Levels: Study
As natural bacterial 'diversity' lessened, HIV viral load increased in infected men, researchers say (Source: Fertility News - Doctors Lounge)
Africa: Geldof Says Australia Aid Cuts Could Have Helped HIV Battle
[AlertNet]Melbourne -Irish campaigner and musician Bob Geldof said on Thursday that achieving the end to poverty was just as possible as achieving the end to AIDS. (Source: AllAfrica News: HIV-Aids and STDs)
Kenya: About Half of HIV Infections Occur in Unions
[The Star]Close to half of HIV infections occur among people who have sex within a union. A HIV report also reveals that key populations including sex workers, men having sex with men, prisoners and injecting drug users account for a third of the new infections. (Source: AllAfrica News: HIV-Aids and STDs)
Latest HIV 'cure' claims prompt calls for more caution
Bone marrow grafts have helped both patients stay all but virus-free for three years. But the disease has come back before in others, and a simpler treatment is needed (Source: New Scientist - HIV and AIDS)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Zimbabwe: HIV/Aids Have Robbed Zimbabwe of a Healthy Workforce - Minister Bimha
[The Herald]THE Minister of Industry and Commerce Mike Bimha has lamented the damage HIV and AIDS have had on the Zimbabwe workforce and said this devastation has reversed development and retarded the economic growth of the country. (Source: AllAfrica News: HIV-Aids and STDs)
Zimbabwe: Parirenyatwa Courts Indian Firm On ARVs
[The Herald]Health and Child Care Minister Dr David Parirenyatwa yesterday met with representatives of an Indian drug manufacturer, Myland, which has shown interest in partnering Zimbabwean pharmaceutical companies to produce anti-retroviral drugs locally.In an interview with The Herald on the sidelines of the 20th International Aids Conference here soon after the meeting, Dr Parirenyatwa said they were still courting the manufacturer and if the deal sailed through, production of the drugs locally would have massive b (Source: AllAfrica News: HIV-Aids and STDs)
Zimbabwe: Remember the Youths in HIV Fight
[The Herald]AT least 12 000 delegates from 200 countries are meeting this week in Melbourne, Australia, for the 20th International AIDS Conference. This comes at a time the United Nations has set a new target of 2030 to eliminate AIDS, TB and malaria as major global killers. Initially all Millennium Development Goals (MDGs) were supposed to be achieved by 2015. That has not been possible. (Source: AllAfrica News: HIV-Aids and STDs)
South Africa: DA Welcomes Additional R1 Billion for ARVs
[DA]The DA welcomes the announcement made yesterday by Health Minister, Dr Aaron Motsoaledi, that an additional 2 million HIV-positive South Africans, with a CD4 count of 500, will be placed on Anti-Retroviral (ARV) treatment over the next 3 years. (Source: AllAfrica News: HIV-Aids and STDs)
Cochlear protests Medicare exclusion of Baha hearing implant
Hearing devices maker Cochlear Limited warns that Medicare's proposed rule change could limit access to certain cochlear implants. A proposed change to Medicare's reimbursement of hearing aids could leave patients on their own when they need the a specific type of bone-anchored hearing aid implant, according to device maker Cochlear Ltd. (ASX:COH). Centers for Medicare and Medicaid Services (CMS), Cochlear Ltd.News Well, Hearing, Implants, Medicare, Reimbursementread more (Source: Mass Device)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Who needs college? Pre-baccalaureate workers a growing percentage of health care workforce
More than half of America's health care workforce has an associate's degree or less, according to a new report from the Brookings Metropolitan Policy Program. The report showed 43 percent of all health care workers fall into the pre-baccalaureate category in the 10 largest pre-baccalaureate occupations. Those 10 occupations include home health aids, registered nurses, personal care aides, practical and vocational nurses, medical and dental assistants, diagnostic and laboratory technologists and? (Source: bizjournals.com Health Care:Physician Practices headlines)
Africa: Communities Must Remain At the Forefront of HIV Response
[Key Correspondents]Governments and policymakers are failing to involve communities in HIV and TB programmes, turning instead to researchers and experts to make key decisions. This issue has triggered debate at the AIDS 2014 conference in Melbourne, Australia (20-25 July) as representatives of some African communities claim they are being locked out of the HIV response. (Source: AllAfrica News: HIV-Aids and STDs)
Africa: We Must Step Up the Pace to End Aids
[Key Correspondents]Malaysian Airlines Flight MH17 was sadly at the centre of discussions as the AIDS 2014 Conference commenced in Melbourne on 20 July. (Source: AllAfrica News: HIV-Aids and STDs)
Africa: Children With HIV Left Behind in the Race Towards Treatment for All
[Key Correspondents]Ahead of this week's 20th International AIDS Conference, experts have warned that children are being left behind in the goal to reach universal access to HIV treatment. (Source: AllAfrica News: HIV-Aids and STDs)
Rwanda: Fight HIV/Aids Stigma in Schools
[New Times]This week's lead story on how schools are dealing with the challenge of HIV-infected students, while encouraging, illustrates just how far we still have to go in the fight against the killer pandemic in our midst. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Africa: U.S Ambassador Calls for LGBT Rights
[VOA]The U.S. ambassador to Australia said it should not be a crime to be a member of the LGBT community. Ambassador John Berry told the 20th international AIDS Conference that the fight against the disease cannot be won by relegating segments of the population to the shadows. (Source: AllAfrica News: HIV-Aids and STDs)
Nigeria: 2.6 Million Living With HIV/Aids to Access Services
[Guardian]Abuja -THE International Federation of Red Cross and Red Crescent Societies (IFRC) has said the 2.6 million people living with HIV in Benue and Cross River States are to benefit from improved access to qualitative treatment. (Source: AllAfrica News: HIV-Aids and STDs)
Nigeria: Nigerians Seek Own HIV/Aids Drugs, Test Kits
[Independent]A cross section of Nigerians has said the country could make remarkable progress in most aspects if the burden of HIV and AIDS is This is in view of reports by the Joint United Nations Programme on HIV/AIDS (UNAIDS) that, Nigeria has the second largest HIV epidemic globally. (Source: AllAfrica News: HIV-Aids and STDs)
Breaking Open Public Places: UNFPA Launches Coolibah - 21 July 2014
MELBOURNE, Australia &ndash; At the International AIDS Conference 2014 today, UNFPA, the United Nations Population Fund, launched a youth networking zone called the coolibah, where, throughout the week, it will host a range of activities for and with young people, including a series of luncheons with leaders in the field of HIV and AIDS. (Source: UNFPA News)
UNFPA engages young people in the fight against HIV - 21 July 2014
MELBOURNE, Australia &ndash; Every hour, about 80 young people are newly infected with HIV, according to the recently released Gap Report by UNAIDS. The participation and leadership of young people will therefore be critical in bringing the global HIV epidemic to an end. Today, at the 20th International AIDS Conference, UNFPA launched a youth networking zone called the &lsquo;coolibah&rsquo;, where young people will be able to speak with leaders in the field of HIV and AIDS. (Source: UNFPA News)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
The prevalence of transmitted HIV drug resistance among MSM in Anhui province, China.
CONCLUSIONS: In Anhui, CRF01_AE strains contributed to most of the HIV infections among MSM, and the prevalence of TDR was relatively low in this population. Further studies should be performed to evaluate the trend of TDR among MSM in Anhui and to inform first-line antiretroviral treatment. PMID: 25035709 [PubMed] (Source: AIDS Research and Therapy)
Virologic outcomes of second-line antiretroviral therapy in Eastern European country of Georgia.
CONCLUSIONS: The study demonstrated favourable virological outcomes of the second-line ART in Georgia. Majority of patients, including IDUs, achieved sustained virological response over 36 month period. The findings highlight the need of improving adherence. PMID: 25035708 [PubMed] (Source: AIDS Research and Therapy)
Nigeria: New Drug Flushes Out HIV... but
[Independent]Scientists say they have made an exciting step towards curing HIV by forcing the virus out of its reservoirs. But they have also warned that when the drug treatment stops, the virus can leap out of the reservoir and renew its assault. (Source: AllAfrica News: HIV-Aids and STDs)
Short Communication: HIV-1 Gag Genetic Variation in a Single Acutely Infected Participant Defined by High-Resolution Deep Sequencing
AIDS Research and Human Retroviruses , Vol. 0, No. 0. (Source: AIDS Research and Human Retroviruses)
Victoria A. Harden, AIDS at 30: A History
(Source: Social History of Medicine)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Rifamycin Analog Production by Combinatorial Biosynthesis [Gene Regulation]
Rifamycin B, a product of Amycolatopsis mediterranei S699, is the precursor of clinically used antibiotics that are effective against tuberculosis, leprosy, and AIDS-related mycobacterial infections. However, prolonged usage of these antibiotics has resulted in the emergence of rifamycin-resistant strains of Mycobacterium tuberculosis. As part of our effort to generate better analogs of rifamycin, we substituted the acyltransferase domain of module 6 of rifamycin polyketide synthase with that of module 2 of rapamycin polyketide synthase. The resulting mutants (rifAT6::rapAT2) of A. mediterranei S699 produced new rifamycin analogs, 24-desmethylrifamycin B and 24-desmethylrifamycin SV, which contained modification in the polyketide backbone. 24-Desmethylrifamycin B was then converted to 24-d...
Raltegravir Not Better Than NRTIs for Refractory HIVRaltegravir Not Better Than NRTIs for Refractory HIV
Raltegravir showed no benefits over nucleoside reverse-transcriptase inhibitors when used in combination with a protease inhibitor as second-line HIV therapy. Medscape Medical News (Source: Medscape Medical News Headlines)
'Kick' Study Excites AIDS Meeting
(MedPage Today) -- MELBOURNE, Australia -- A trial with only six patients and no dramatic clinical outcomes rarely creates much of a buzz, but delegates to the International AIDS Conference here are talking up just such a study. (Source: MedPage Today Infectious Disease)
HIV Meds May Also Help Control Hepatitis C, Study Finds
For people infected with both viruses, early treatment is critical, researchers report (Source: Fertility News - Doctors Lounge)
Clinton to AIDS Conference: Step It Up
(MedPage Today) -- MELBOURNE, Australia -- The destruction of a jet with six AIDS researchers and activists aboard is a "stark reflection" of the negative side of an interdependent world, former President Bill Clinton said here. (Source: MedPage Today Public Health)
The Use of Positive Psychology in Addiction Treatment
?Positive Psychology is the scientific study of the strengths and virtues that enable individuals and communities to thrive." Here is how positive psychology aids addiction treatment.read more (Source: Psychology Today Addiction Center)
Malawi: None Reporting of HIV Activities Affecting Progress in HIV Fight
[Malawi News Agency]Salima -The HIV review meeting for Salima district council has exposed under reporting of HIV activities by stake holders, as only 30 percent of organizations in this sector reported their 2013-2014 activities. (Source: AllAfrica News: HIV-Aids and STDs)
Kenya: Kenyans Having Sex Without Protection
[The Star]Kenyans are continuously having sex without a condom despite not knowing the HIV status of their partners. A HIV report by the health ministry shows that only 5% of women between 25-64 years and 11% of men in the same age group consistently use a condom with partners of unknown status. (Source: AllAfrica News: HIV-Aids and STDs)
South Africa: SA's Big HIV/Aids 2030 Plan
[SAnews.gov.za]Health Minister Dr Aaron Motsoaledi says government has big plans to turn the tide on HIV/Aids by 2030, in line with the target set by delegates at the International Aids Conference in Australia. (Source: AllAfrica News: Health and Medicine)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Africa: U.S. Awards Another $500 Million to Achieve AIDS-Free Generation
[State Department]Melbourne, Australia -More than $500 million in additional U.S. funding will support global HIV and AIDS response efforts with 19 partners. (Source: AllAfrica News: Health and Medicine)
Africa: UNDP Administrator Sees Stronger Role for Lawmakers in Eradicating AIDS
[UNDP]Melbourne, Australia -Tackling HIV requires courageous and committed policy-makers and law-makers said the UN's development chief at the 20th International AIDS Conference. (Source: AllAfrica News: HIV-Aids and STDs)
Kenya: 65 Percent of New HIV Infections in Only Nine Counties
[The Star]65% of new HIV infections occur in only nine of the 47 counties. The Kenya HIV prevention revolution road map shows that new infection rates are highest in Homa Bay, Kisumu, Siaya, Migori and Kisii counties respectively. (Source: AllAfrica News: HIV-Aids and STDs)
Zimbabwe: HIV Disclosure - Changing Ourselves, Changing Others
[New Zimbabwe]When will policy makers, politicians and academics start to think upstream, in order to change their own and their employees' attitudes towards HIV before seeking to change the attitudes of others? (Source: AllAfrica News: HIV-Aids and STDs)
Namibia: Group Fights HIV in Truck Drivers
[Namibian]ABOUT 148 truck drivers out of 1 104 who tested for HIV between 2012 and June 2014 were positive, according to statistics given by the Walvis Bay Corridor Group (WBCG). (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Africa: Sex Workers Seek HIV Prevention
[VOA]A new series in the medical journal The Lancet says achieving an AIDS-free generation will not be possible unless the human rights of sex workers are recognized. Researchers say sex workers face violence and discrimination and are not able to access the care, treatment and prevention measures they need. (Source: AllAfrica News: Health and Medicine)
South Africa: Aids Still Extracting a Deadly Price, but SA Is Making Progress
[Health-e]South Africa has more Aids-related deaths than any country in the world, but deaths of young children have decreased more than ten-fold in the past decade and tuberculosis (TB) deaths have decreased by 6 percent. (Source: AllAfrica News: HIV-Aids and STDs)
Uganda: At Lake Katwe Condoms Protect Men From Salt
[Observer]Around the salty Lake Katwe in western Uganda, condoms have taken on a unique usage, rather than preventing the spread of sexually-transmitted diseases such as HIV/Aids. (Source: AllAfrica News: HIV-Aids and STDs)
Zimbabwe: Sex-for-Food Scheme Expose Children to STIs
[CAJ News]Masvingo -HUNDREDS of people, among them monitors as young as 14, have contracted sexually transmitted diseases (STDs) since the beginning of the year as the situation at the Chingwizi transit camp turn dire by the day. (Source: AllAfrica News: HIV-Aids and STDs)
On the Evolution of AIDS/HIV Treatment: An Optimal Control Approach.
Authors: Biswas HA Abstract After more than 30 years of continuous research as well as unselfish efforts, tremendous and exciting developments have been achieved towards the evolution of HIV treatments both in the directions of antiretroviral therapy and effective vaccine for HIV positive patients. Recent research shows that triple-drug antiretroviral therapy can 'functionally cure' [1, 2] the HIV positive patients, which is a milestone in the therapeutic treatments of AIDS. Despite the significant progress on the evolution of AIDS/HIV treatments, it is still a curse for the humanity and until today the world's most serious epidemic as well as leading infectious killer disease. However, Millennium Development Goals (MDGs) Getting to Zero shows a hope to build up a new world without...<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Expression Profiles of Endogenous Retroviral Envelopes in Macaca Mulatta (Rhesus Monkey)
AIDS Research and Human Retroviruses , Vol. 0, No. 0. (Source: AIDS Research and Human Retroviruses)
Latest HIV purge claims prompt calls for more caution
Bone marrow grafts have helped both patients stay all but virus-free for three years. But the disease has come back before in others, and a simpler treatment is needed (Source: New Scientist - HIV and AIDS)
Problem-Focused Coping: Skipped-Generation Caregivers Affected by HIV/AIDS in Vietnam
In this article, we examine skipped-generation caregivers who foster their grandchildren orphaned by HIV/AIDS in Vietnam. We investigated the challenges facing this population and the ways in which grandparents handled their trials on behalf of their families. Specifically, how did caregivers make sense of their roles, and how did these meanings inform their coping strategies? We conducted in-depth qualitative interviews with 21 older caregivers and 7 key informants and selected 5 caregivers from the sample to complete participant observations. The participants understood coping as problem-focused coping; for example, by considering a set of caregiving-related activities that included providing childcare, making money, borrowing money, cooking, and doing other daily chores. The voices of o...
The Organelle-focused Proteomes and Interactomes in Rice.
Authors: Liu L, Jiang L, Chen M Abstract Protein subcellular localization has been a long-standing key problem in investigating proteins' function, which provides important clues for revealing their functions and aids in understanding their interactions with other biomolecules at the cellular level. Here, we systematically defined the organelle-focused proteome and interactome in Oryza sativa. A total of 83.42% of the whole rice proteome obtained their subcellular localizations based on manual annotation, manual adjustment and predictors' cross validation. The final organelle-focused interactome were located in nine organelles. Furthermore, we discussed the cross talk bias between different organelles and the function organization accounting for nine organelles. Motif analysis illu...
Celastrol ameliorates HIV-1 Tat-induced inflammatory responses via NF-kappaB and AP-1 inhibition and heme oxygenase-1 induction in astrocytes.
In this study, we investigated the modulatory effects of celastrol on HIV-1 Tat-induced inflammatory responses and the molecular mechanisms underlying its action in astrocytes. Pre-treatment of CRT-MG human astroglioma cells with celastrol significantly inhibited HIV-1 Tat-induced expression of ICAM-1/VCAM-1 and subsequent monocyte adhesiveness in CRT-MG cells. In addition, celastrol suppressed HIV-1 Tat-induced expression of pro-inflammatory chemokines, such as CXCL10, IL-8, and MCP-1. Celastrol decreased HIV-1 Tat-induced activation of JNK MAPK, AP-1, and NF-?B. Furthermore, celastrol induced mRNA and protein expression of HO-1 as well as Nrf2 activation. Blockage of HO-1 expression using siRNA reversed the inhibitory effect of celastrol on HIV-1 Tat-induced inflammatory responses. Thes...<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
eSNaPD: A Versatile, Web-Based Bioinformatics Platform for Surveying and Mining Natural Product Biosynthetic Diversity from Metagenomes.
Authors: Reddy BV, Milshteyn A, Charlop-Powers Z, Brady SF Abstract Environmental Surveyor of Natural Product Diversity (eSNaPD) is a web-based bioinformatics and data aggregation platform that aids in the discovery of gene clusters encoding both novel natural products and new congeners of medicinally relevant natural products using (meta)genomic sequence data. Using PCR-generated sequence tags, the eSNaPD data-analysis pipeline profiles biosynthetic diversity hidden within (meta)genomes by comparing sequence tags to a reference data set of characterized gene clusters. Sample mapping, molecule discovery, library mapping, and new clade visualization modules facilitate the interrogation of large (meta)genomic sequence data sets for diverse downstream analyses, including, but not limi...
Spatial Relationships Between Gay Stigma, Poverty, and HIV Infection Among Black and White Men Who Have Sex with Men in Atlanta
AIDS Research and Human Retroviruses , Vol. 0, No. 0. (Source: AIDS Research and Human Retroviruses)
Sexual behavior among Brazilian adolescents, National Adolescent School-based Health Survey (PeNSE 2012)
CONCLUSION: The information on preventing pregnancy and STD/AIDS need to be disseminated before the 9th grade. Social inequalities negatively affect risky sexual behavior. Substance use is strongly associated with unprotected sex. Information on the prevention of pregnancy and STD/AIDS need to be disseminated early. OBJETIVO: Este estudo descreve o comportamento sexual entre estudantes que participaram da Pesquisa Nacional sobre a Saúde do Escolar (PeNSE) 2012 e investiga se as desigualdades sociais, o uso de substâncias psicoativas e a presença de informações sobre a saúde sexual e reprodutiva na escola estão associados a diferenças nesse comportamento. METODOLOGIA: A variável resposta foi o comportamento sexual descrito em três categorias (nunca teve relação sexual, teve rel...
Sexual behavior of school-aged adolescents in the city of Goiânia, Goiás
CONCLUSION: Results showed a need for health education measures involving education and health professionals, as well as parents, to reduce the discrepancies found regarding sex and type of school. OBJETIVO: Investigar as características do comportamento sexual de adolescentes escolares e verificar se há diferenças em relação ao sexo dos estudantes e ao tipo de escola. MÉTODOS: Estudo transversal utilizando dados da Pesquisa Nacional de Saúde do Escolar (PeNSE) 2009, realizada pelo Ministério da Saúde em parceria com o IBGE. A amostra foi composta por 3.099 escolares do 9° ano residentes em Goiânia (GO), com predomínio das idades de 13 a 15 anos, que responderam um questionário sobre fatores de risco e proteção à saúde. Na análise estatística, foi utilizado o teste de R...
Credibility Among Gay Men Gives Leverage to New York City?s New Chief of H.I.V. Prevention
Dr. Demetre Daskalakis will soon be in charge of one of the health department?s largest bureaus at a critical moment in the history of the virus that causes AIDS. (Source: NYT Health)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Breaking Open Public Places: UNFPA Launches Coolibah - 21 July 2014
MELBOURNE, Australia &ndash; At the International AIDS Conference 2014 today, UNFPA, the United Nations Population Fund, launched a youth networking zone called the coolibah, where, throughout the week, it will host a range of activities for and with young people, including a series of luncheons with leaders in the field of HIV and AIDS. (Source: UNFPA News)
UNFPA engages young people in the fight against HIV - 21 July 2014
MELBOURNE, Australia &ndash; Every hour, about 80 young people are newly infected with HIV, according to the recently released Gap Report by UNAIDS. The participation and leadership of young people will therefore be critical in bringing the global HIV epidemic to an end. Today, at the 20th International AIDS Conference, UNFPA launched a youth networking zone called the &lsquo;coolibah&rsquo;, where young people will be able to speak with leaders in the field of HIV and AIDS. (Source: UNFPA News)
DHAP Annual Report
This document highlights programmatic activities of the CDC Division of HIV/AIDS Prevention in 2013. (Source: CDC HIV/AIDS Prevention)
New HIV Guidelines Released by WHONew HIV Guidelines Released by WHO
The recommendations target marginalized groups reportedly responsible for much of the global HIV epidemic. Medscape Medical News (Source: Medscape Medical News Headlines)
Scientists cut HIV directly out of infected human genome using molecular tools
Scientists have taken an ?important step? towards a permanent cure for AIDS by using specially designed enzymes to physically cut the HIV virus out of an infected human genome. (Source: The Independent - Science)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Scientists cut HIV directly out of the human genome using molecular tools
Scientists have taken an ?important step? towards a permanent cure for AIDS by using specially designed enzymes to physically cut the HIV virus out of the human genome. (Source: The Independent - Science)
Africa: Helen Clark - Speech On "Beyond the MDGs: HIV and the Post-2015 Agenda" At the 20th International Aids Conference
[UNDP]"Beyond the MDGs: HIV and the Post -"2015 Agenda" (Source: AllAfrica News: Pregnancy and Childbirth)
Africa: HIV/Aids Resource Adds Data From More Than 100 Countries
[State Department]Washington -The U.S. Census Bureau on July 21 released its annually updated interactive global resource on HIV prevalence, AIDS cases and AIDS deaths. The database is the most comprehensive resource of its kind in the world, according to the U.S. Commerce Department, which includes the Census Bureau. (Source: AllAfrica News: HIV-Aids and STDs)
Africa: USAID Announces +$500 Million for New Efforts to Reach an Aids-Free Generation At Conference in Melbourne, Australia
[USAID]Melbourne -Major awards with 19 partners to support global HIV and AIDS response (Source: AllAfrica News: HIV-Aids and STDs)
HIV: Viral Rebound After Bone Marrow TransplantHIV: Viral Rebound After Bone Marrow Transplant
Case reports of 2 men with HIV who were in transient remission after bone marrow transplant showed that their viral loads rebounded after stopping ART. Medscape Medical News (Source: Medscape Medical News Headlines)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
South Africa: Better, Shorter TB Treatment - Thanks to SA Scientists
[Health-e]South African scientists may be en route to developing shorter, better tuberculosis (TB) treatment, according to research released at the International AIDS Conference in Melbourne, Australia. (Source: AllAfrica News: Tuberculosis)
Africa: African Anti-Gay Laws Challenge Health Care
[VOA]African Anti -President Goodluck Jonathan of Nigeria and President Yoweri Museveni of Uganda are two African leaders who embrace legislation which targets the gay community. In Uganda, an anti-homosexuality law criminalizes same-sex relations, while in Nigeria, same sex couples that show affection in public risk ten years imprisonment. The laws in both countries are forcing communities vulnerable to HIV deeper into the shadows. (Source: AllAfrica News: HIV-Aids and STDs)
Nigeria: HIV/Aids Cure Suffers Setback With Demise of Joep Lange
[Leadership]Abuja -The United Nations Agency for HIV/AIDS (UNAIDS), has expressed deep sadness over the loss of life of the passengers and crew of flight MH17, which crashed over eastern Ukraine on Thursday, July 17, 2014, among them a staff of the World Health Organisation (WHO). (Source: AllAfrica News: HIV-Aids and STDs)
Africa: Does Anybody Remember Aids?
[GroundUp]This week thousands of activists, scientists and government officials will troop to Melbourne, Australia, to participate in the 20th International AIDS Conference. (Source: AllAfrica News: HIV-Aids and STDs)
Breaking Open Public Places: UNFPA Launches Coolibah - 21 July 2014
MELBOURNE, Australia &ndash; At the International AIDS Conference 2014 today, UNFPA, the United Nations Population Fund, launched a youth networking zone called the coolibah, where, throughout the week, it will host a range of activities for and with young people, including a series of luncheons with leaders in the field of HIV and AIDS. (Source: UNFPA News)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
UNFPA engages young people in the fight against HIV - 21 July 2014
MELBOURNE, Australia &ndash; Every hour, about 80 young people are newly infected with HIV, according to the recently released Gap Report by UNAIDS. The participation and leadership of young people will therefore be critical in bringing the global HIV epidemic to an end. Today, at the 20th International AIDS Conference, UNFPA launched a youth networking zone called the &lsquo;coolibah&rsquo;, where young people will be able to speak with leaders in the field of HIV and AIDS. (Source: UNFPA News)
Oral Pre-Exposure Prophylaxis (PrEP) for Prevention of HIV in Serodiscordant Heterosexual Couples in the United States: Opportunities and Challenges
AIDS Patient Care and STDs , Vol. 0, No. 0. (Source: AIDS Patient Care and STDs)
Exari Launches 'SmartDocs'; Aids ACLA Members in Complex Clause Creation, Negotiation
(Source: Medical News (via PRIMEZONE))
More bad news in fight against persistent HIV reservoirs
July has been a particularly trying month for HIV/AIDS researchers as they mourned the loss of colleagues killed in a militant attack and received new reports of the virus' remarkable tenacity. (Source: Los Angeles Times - Science)
Delegates mourn MH17 passengers
Authors: Katia Moskvitch & Edward Susman AIDS conference tries to draw inspiration from lost scientists. (Source: Nature)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Antiretroviral-Free HIV-1 Remission and Viral Rebound After Allogeneic Stem Cell Transplantation: Report of 2 Cases.
Conclusion: Allogeneic HSCT may lead to loss of detectable HIV-1 from blood and gut tissue and variable periods of antiretroviral-free HIV-1 remission, but viral rebound can occur despite a minimum 3-log10 reduction in reservoir size. Long-lived tissue reservoirs may have contributed to viral persistence. The definition of the nature and half-life of such reservoirs is essential to achieve durable antiretroviral-free HIV-1 remission. Primary Funding Source: Foundation for AIDS Research and National Institute of Allergy and Infectious Diseases. PMID: 25047577 [PubMed - as supplied by publisher] (Source: Annals of Internal Medicine)
AIDS Conference Organizers Honor Delegates Downed in PlaneAIDS Conference Organizers Honor Delegates Downed in Plane
AIDS 2014 opened with a moment of silence as participants paid tribute to at least 6 registered attendees who lost their lives on the Malaysia Airlines flight en route to the conference. Medscape Medical News (Source: Medscape Allergy Headlines)
Efficacy of an Evidence-Based ARV Adherence Intervention in China
AIDS Patient Care and STDs , Vol. 0, No. 0. (Source: AIDS Patient Care and STDs)
Scientists Snipped HIV Out of Human DNA
Molecular tool might lead to more definitive treatment, but current research didn't treat patients, just cells Source: HealthDay Related MedlinePlus Pages: Genes and Gene Therapy, HIV/AIDS (Source: MedlinePlus Health News)
Animal Experiments Shed Light on HIV's Ability to Hide
Viral 'reservoir' in body develops earlier than thought, thwarting attempts at cure, scientists saySource: HealthDay Related MedlinePlus Page: HIV/AIDS (Source: MedlinePlus Health News)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Updates from Team Nduruma
Mambo! VP3 here in the lovely village of Nduruma. We are rounding up our second week in the village and have enjoyed getting to know Nduruma and its inhabitants a little more everyday. Before we delve into the nitty gritty of our lives here, a brief introduction to the Nduruma SIC team is in order. &nbsp; Aaron: Aaron is from the University of Dodoma. He hates music and owns dirt-repelling white shoes. Poa! Keaton: Keaton is from the University of San Francisco. He is highly praised here in Nduruma. Everybody just loves him. Ben: Ben is from Stanford. He loves (LOVES) cats and has one dance move. Taylor: Taylor is from UCLA. She is well traveled and coming to Tanzania was NO big deal. She is open to trying all sorts of food. Hilal: Hilal is from the University of Dodoma. He doesn?t reall...
Hello from Team Marurani!
We wake up to the alarms of our smart phones, or more likely, to the domestic noises that have undoubtedly started with a punctuality and intensity I could not imagine for such an hour of the day. Tea and coffee is on the table with sweet smelling, oily tasting simple donuts, called mandazi. We bow our heads as our house father, or baba, mutters thanks in Swahili to God. We dress ourselves as the locals do, long traditional skirts and blouses for women, t-shirts, jeans, and sneakers for men. We try to fit into this foreign world. We lives in the same kind of houses, use the same blankets for showers, and walk the same dirty roads. We try, at least, to live the same kind of life as those who we are teaching. We dot it to create solidarity and empathy. By living in the field away form famili...
HIV diagnosis rate drops significantly
It's a sign that the AIDS epidemic may be slowing, but some exceptions raise concerns (Source: Health News: CBSNews.com)
Breaking Open Public Places: UNFPA Launches Coolibah - 21 July 2014
MELBOURNE, Australia&mdash; At the International AIDS Conference 2014 today, UNFPA launched a youth networking zone called the coolibah, where, throughout the week, it will host a range of activities for and with young people, including a series of luncheons with leaders in the field of HIV and AIDS. (Source: UNFPA News)
Kenya: Controlling HIV-Aids By 2030 Is Possible - UNAIDS
[The Star]HIV/Aids, one of Africa's biggest killer, may be no more or will be under control in the next 20 or so years if medication is availed to everyone infected and awareness spread, statistics show. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Africa: Controlling HIV-Aids By 2030 Is Possible - UNAIDS
[The Star]HIV/Aids, one of Africa's biggest killer, may be no more or will be under control in the next 20 or so years if medication is availed to everyone infected and awareness spread, statistics show. (Source: AllAfrica News: HIV-Aids and STDs)
'Bad' laws hurt sex workers, gays from Uganda to Nepal, AIDS meeting told
MELBOURNE (Thomson Reuters Foundation) - After Uganda passed a law that punished gay sex with long prison sentences, Daisy Nakato got a visit from the police. (Source: Reuters: Health)
Kenya: HIV Message Needs to Target Young People
[The Star]HIV Message Needs To Target Young People. Photo/Monica Mwangi (Source: AllAfrica News: HIV-Aids and STDs)
Africa: Circumcision Does Not Promote Risky Behaviour
[VOA]A new study that could boost HIV prevention efforts says African men do not engage in riskier sexual behaviour after being circumcised. Research has shown that circumcision can greatly reduce men's risk of being infected with the AIDS virus. The study's been released as the 20th International AIDS Conference opens in Melbourne, Australia. (Source: AllAfrica News: Health and Medicine)
Retention in HIV Care in Year 1: Who's In and Who's Out?Retention in HIV Care in Year 1: Who's In and Who's Out?
Which patients are less likely to be retained in HIV care? Journal of the International Association of Providers of AIDS Care (Source: Medscape Today Headlines)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Africa: Helen Clark - Keynote Address to the Meeting of the Parliamentarians At the 20th International Aids Conference
[UNDP]Helen Clark, UNDP Administrator (Source: AllAfrica News: HIV-Aids and STDs)
Nigeria: Nigeria Records 35 Percent Drop in HIV Infections-Report
[Daily Trust]A new global report by UNAIDS indicates that new HIV infections in Nigeria have declined by 35% in the past three years. (Source: AllAfrica News: HIV-Aids and STDs)
Nigeria: 2.6 Million Infected People to Access HIV/Aids Services
[Guardian]Abuja -THE International Federation of Red Cross and Red Crescent Societies (IFRC) has said the 2.6 million people living with HIV/AIDS in Benue and Cross River states are to benefit from improved access to quality treatment. (Source: AllAfrica News: HIV-Aids and STDs)
Tanzania: HIV/Aids Research Suffers Blow As Leading Don Dies
[Daily News]RESEARCH on HIV/ AIDS has suffered a setback following the death of a leading scientist, Dr Joep Lange (59) who was one of the passengers in the ill- fated Malaysia Airlines plane that crashed in eastern Ukraine on Thursday, claiming 298 lives. (Source: AllAfrica News: HIV-Aids and STDs)
Nigeria: Nigeria Achieves 35 Percent Drop in New HIV Infections
[Leadership]A new global report by the UNAIDS has revealed that new HIV infections have declined by 35% in the past three years in Nigeria. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Nigeria: 'Fight Against HIV Still Has a Long Way to Go'
[Leadership]Leading researchers have warned complacency about HIV and AIDS could derail the enormous progress achieved in the three-decade fight against the diseases. (Source: AllAfrica News: HIV-Aids and STDs)
Africa: New TERG Review Offers Window Into Challenges Inhibiting Impact in World's Most Fragile States
[GFO]Recommendations include wider collaboration, greater flexibility and easing of the co-financing requirements (Source: AllAfrica News: HIV-Aids and STDs)
Africa: Gaps Mark Several of the FM's First Concept Note Submissions
[GFO]CCMs given new guidance by Secretariat after Technical Review Panel asks for stronger submissions (Source: AllAfrica News: HIV-Aids and STDs)
South Africa: SA Clinicians Society Mourns Deaths On Flight 17
[Health-e]Dutch HIV expert Joep Lange, killed on Flight 17, was a 'friend of Africa' (Source: AllAfrica News: HIV-Aids and STDs)
Africa: At Conference, UNAIDS Chief Calls for End to 'Hypocrisy' in Fighting HIV/Aids
[UN News]The head of the United Nations agency dealing with HIV and AIDS today urged world leaders at an international conference in Australia to end the hypocrisy on sex and make treatment and reproductive health education universally available. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
South Africa: HIV Diagnosis Unites Young Family
[Health-e]For some women, an HIV-positive diagnosis during pregnancy can spark domestic violence and abandonment. For Nokuzola Tholeduna, her diagnosis brought her young family together. (Source: AllAfrica News: HIV-Aids and STDs)
Africa: Youth Taking Lead at Aids 2014
[UNAIDS]The passion, dedication and commitment that young people are bringing to the AIDS response, driving the agenda and taking a leadership role, were celebrated by UNAIDS Executive Director Michel Sidibé in closing remarks at the AIDS 2014 youth preconference event. (Source: AllAfrica News: HIV-Aids and STDs)
Africa: People Living With HIV Lead Response to Discrimination
[Key Correspondents]When Malawian Martha Dzuwa was diagnosed with HIV, people in her community labelled her "a dead fellow walking". (Source: AllAfrica News: HIV-Aids and STDs)
Nigeria: Kaduna Distributes N7.5 Million Food to People Living With HIV
[Independent]The Kaduna State Action Committee on AIDS on Friday distributed food items worth N7.5 million as assistance to people living with HIV/AIDS. (Source: AllAfrica News: Health and Medicine)
HIV Prevention and Treatment Guidelines Released (FREE)
By Kelly Young Edited by Susan Sadoughi, MD, and André Sofair, MD, MPH The International AIDS Society-USA has released two sets of clinical guidelines on preventing and treating HIV, in conjunction with the AIDS 2014 conference and ? (Source: Physician's First Watch current issue)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Featured in NEJM Journal Watch: Mood Solemn in Melbourne as AIDS 2014 Starts (FREE)
By the NEJM Journal Watch Editors There is unquestionably a shadow cast over this year's international AIDS meeting here in Melbourne, writes ? (Source: Physician's First Watch current issue)
The global burden of neurologic diseases
WHO categorizes causes of death and disability into (1) communicable diseases, maternal and perinatal conditions, and nutritional deficiencies; (2) non-communicable diseases (NCD); and (3) injuries. NCD are the leading cause of death and disability globally and are rising as a result of demographic and epidemiologic changes occurring in both developed and developing countries.1,2 Increasing life expectancies, unhealthy diet, physical inactivity, tobacco use, and harmful use of alcohol contribute to the growing incidence and prevalence of NCD, such as heart disease, stroke, diabetes, cancers, and chronic respiratory diseases. Deaths from communicable diseases, such as HIV/AIDS, tuberculosis, and malaria, are declining as a result of billions of dollars of annual international and domestic f...
Use of non?drug non?operative interventions by community?dwelling people with hip and knee osteoarthritis
Conclusion: Use of non?drug non?operative interventions was low amongst people with hip and knee OA. Our findings show evidence?practice gaps particularly with respect to the interventions most strongly recommended in clinical guidelines for hip and knee OA (weight loss and exercise). © 2014 American College of Rheumatology. (Source: Arthritis Care and Research)
The Week Ahead: Science Flows from AIDS Meeting
(MedPage Today) -- Science reports start to flow in earnest from the International AIDS Conference in Melbourne, Australia, although the tragedy of several delegates killed while en route to the meeting remains fresh. (Source: MedPage Today Public Health)
Joep Lange, The Physician-Scientist Before Medical Diplomat
The prominent Dutch HIV/AIDS figure made a significant global impact on treatment of the disease, especially in developing nations. But he was first a scientist at the front lines of a mysterious, just-discovered virus. (Source: Forbes.com Healthcare News)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
At conference, UNAIDS chief calls for end to &#39hypocrisy&#39 in fighting HIV/AIDS
The head of the United Nations agency dealing with HIV and AIDS today urged world leaders at an international conference in Australia to end the hypocrisy on sex and make treatment and reproductive health education universally available. (Source: UN News Centre - Women, Children, Population)
With Malaysia Airlines Crash, A Loss For AIDS Research
A number of scientists and others members of the AIDS research community died in the downing of Malaysia Airlines Flight 17 over Ukraine. NPR's Kelly McEvers speaks with journalist and editor in chief of HIV Plus magazine Diane Anderson-Minshall about the loss.&raquo; E-Mail This (Source: NPR Health and Science)
New HIV prevention recommendations combine biomedical, behavioral approaches
In an innovative approach to HIV prevention, an interdisciplinary group of experts has come together for the first time to lay out a framework of best practices to optimize the role of the clinician in achieving an AIDS-free generation. The recommendations are intended as guidelines for clinicians to implement a combined biomedical-behavioral approach to HIV care and prevention. They are based on a comprehensive review of data that was either published or presented at scientific conferences over the past 17 years. (Source: ScienceDaily Headlines)
HIV diagnosis rate falls by a third in U.S.: researchers
WASHINGTON (Reuters) - The annual rate of diagnosis with HIV, the virus that causes AIDS, fell by a third in the United States between 2002 and 2011, researchers reported on Saturday. (Source: Reuters: Health)
HIV Diagnoses Down in U.S., Except for Young Gay Males: CDC
Messages about safe sex may be falling on deaf ears, researcher notes Source: HealthDay Related MedlinePlus Pages: Gay, Lesbian, Bisexual and Transgender Health, HIV/AIDS, Health Disparities (Source: MedlinePlus Health News)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
AIDS Conference Mourning Six Lost in Crash
(MedPage Today) -- MELBOURNE, Australia -- Six AIDS researchers and activists were beginning their journey to the International AIDS Conference here when their airliner was shot down over Ukraine. (Source: MedPage Today Infectious Disease)
Malawi: Sex Initiation Puts Girls At Risk for HIV
[VOA]In Malawi, almost a third of new HIV cases occur in women under the age of 30, in part because of traditional coming-of-age ceremonies that introduce young girls to sex, according to AIDS activists. (Source: AllAfrica News: Health and Medicine)
Africa: Persecution of Homosexuals Hinders Fight Against Aids
[Deutsche Welle]Life is dangerous for Africa's gays and lesbians, despite a resolution from the African Commission for Human Rights. The UN warns that the persecution of homosexuals is hindering the fight against AIDS. (Source: AllAfrica News: Health and Medicine)
AIDS researchers, activists believed among Malaysia plane victims
Malaysia Airlines Flight 17 tragedy believed to have taken the lives of many influential people working in science and activism for HIV/AIDS (Source: Health News: CBSNews.com)
Top HIV/AIDS Researchers Killed on Malaysian JetTop HIV/AIDS Researchers Killed on Malaysian Jet
An unconfirmed number of the world's leading HIV/AIDS researchers were among the 298 people killed on a Malaysian passenger jet that was shot down in eastern Ukraine. Medscape Medical News (Source: Medscape Hiv-Aids Headlines)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Combination treatment for Hep C associated with favorable response among patients with HIV
(The JAMA Network Journals) HIV-infected patients also infected with hepatitis C virus who received a combination of the medications sofosbuvir plus ribavirin had high rates of sustained HCV virologic response 12 weeks after cessation of therapy, according to a study in the July 23/30 issue of JAMA, a theme issue on HIV/AIDS. (Source: EurekAlert! - Infectious and Emerging Diseases)
Growth hormone analog may reduce risk of fatty liver disease in HIV-infected patients
(The JAMA Network Journals) In a preliminary study, HIV-infected patients with excess abdominal fat who received the growth hormone-releasing hormone analog tesamorelin for 6 months experienced modest reductions in liver fat, according to a study in the July 23/30 issue of JAMA, a theme issue on HIV/AIDS. Patients infected with HIV demonstrate a high prevalence of nonalcoholic fatty liver disease, estimated at 30 percent to 40 percent. (Source: EurekAlert! - Medicine and Health)
Offering option of initial HIV care at home increases use of antiretroviral therapy
(The JAMA Network Journals) Among adults in the African country of Malawi offered HIV self-testing, optional home initiation of care compared with standard HIV care resulted in a significant increase in the proportion of adults initiating antiretroviral therapy, according to a study in the July 23/30 issue of JAMA, a theme issue on HIV/AIDS. (Source: EurekAlert! - Medicine and Health)
Study examines rate of HIV diagnosis in US
(The JAMA Network Journals) The annual HIV diagnosis rate in the U.S. decreased more than 30 percent from 2002-2011, with declines observed in several key populations, although increases were found among certain age groups of men who have sex with men, especially young men, according to a study in the July 23/30 issue of JAMA, a theme issue on HIV/AIDS. (Source: EurekAlert! - Medicine and Health)
New HIV prevention recommendations combine biomedical and behavioral approaches
(Emory Health Sciences) In an innovative approach to HIV prevention, an interdisciplinary group of experts has come together for the first time to lay out a framework of best practices to optimize the role of the clinician in achieving an AIDS-free generation. (Source: EurekAlert! - Medicine and Health)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
[Editorial] HIV: science and stigma
Today's issue of The Lancet is dedicated to HIV to coincide with the 20th International AIDS Conference ( AIDS 2014) in Melbourne, Australia (July 20?25, 2014). This year, the biennial meeting?the biggest global gathering of HIV scientists, health-care workers, and activists?has made stigma and discrimination one of its main concerns. Such an emphasis is sadly as necessary today as it was in the very early days of the disease. Worldwide, discriminatory environments that fuel HIV epidemics have remained entrenched in some countries and resurged in others. (Source: LANCET)
[Comment] Antiretroviral therapy: stubborn limitations persist
The development in the mid-1990s of combination antiretroviral treatment (ART) for the management of HIV infections is one of medicine's greatest success stories. For individuals who can access and adhere to treatment at early stages of the infection, the risk of developing an AIDS-defining complication is vanishingly small. Treatment, however, does not fully restore health. Treated adults have a higher than expected risk of developing many non-AIDS complications, including cardiovascular disease and cancer. (Source: LANCET)
[Articles] Trends in underlying causes of death in people with HIV from 1999 to 2011 (D:A:D): a multicohort collaboration
Recent reductions in rates of AIDS-related deaths are linked with continued improvement in CD4 cell count. We hypothesise that the substantially reduced rates of liver disease and cardiovascular disease deaths over time could be explained by improved use of non-HIV-specific preventive interventions. Non-AIDS cancer is now the leading non-AIDS cause and without any evidence of improvement. (Source: LANCET)
[Seminar] HIV infection: epidemiology, pathogenesis, treatment, and prevention
HIV prevalence is increasing worldwide because people on antiretroviral therapy are living longer, although new infections decreased from 3·3 million in 2002, to 2·3 million in 2012. Global AIDS-related deaths peaked at 2·3 million in 2005, and decreased to 1·6 million by 2012. An estimated 9·7 million people in low-income and middle-income countries had started antiretroviral therapy by 2012. New insights into the mechanisms of latent infection and the importance of reservoirs of infection might eventually lead to a cure. (Source: LANCET)
Aids deaths tumble but rising resistance to HIV drugs threatens gains
Warning over growing resistance to antiretrovirals dampens hopes that Aids can be eliminated by 2030 Continue reading... (Source: Guardian Unlimited Science)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Leading AIDS Researcher, ?Always Traveling,? Is Killed on His Way to a Conference
Joep Lange, a pioneer from the early years of the AIDS crisis, played a key role in making H.I.V. treatments available in the developing world. (Source: NYT Health)
This Week: Crash Devastates AIDS World, Pill Looks Matter
(MedPage Today) -- The deaths of HIV/AIDS researchers en route to an AIDS conference, a study highlighting the importance of a pill's appearance, and "assistant physicians" topped this week's news at MedPage Today. (Source: MedPage Today Cardiovascular)
A Pillar Of AIDS Research And Activism, Lost With Shot-Down Jet
Malaysia Airlines Flight 17 had been carrying several researchers and activists on their way to a global AIDS conference in Australia. Among them was Dr. Joep Lange, a leading researcher and former president of the International AIDS Society. He was a giant in the field and a mentor to many.&raquo; E-Mail This (Source: NPR Health and Science)
MH17 Malaysia Airlines crash: Tributes paid to world-renowned AIDS researcher on board stricken plane
Friends and colleagues of Professor Joep Lange, a world-renowned Aids researcher who was on board the stricken Malaysian flight, paid tribute yesterday to his ?tireless? efforts towards defeating HIV/Aids. (Source: The Independent - Science)
Remembrances of AIDS and HIV Workers Killed in Shot-Down Plane
HIV health workers, including one from the WHO, and at least one top AIDS researcher were among those killed when a Malaysia Airlines plane was shot down over Ukraine -- Read more on ScientificAmerican.com (Source: Scientific American - Official RSS Feed)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Interleukin-10 aids survival of cells transplanted to repair cardiac tissues after MI
Three groups of rats modeled with a myocardial infarction were treated with smooth muscle cell injections into the MI-damaged area of the heart in a new study. One group received unmodified autologous SMCs; another received unmodified allogenic SMCs; the last group received allogenic SMCs modified with interleukin 10 - a small, anti-inflammatory protein. The group receiving allogenic SMCs modified with IL-10 demonstrated cell survival, improved heart function, and protection against the host's rejection of the allogenic SMCs. (Source: ScienceDaily Headlines)
Leading AIDS Researcher Killed in Malaysia Airlines Flight 17 Crash
Dr. Joep Lange, a pioneer from the early years of the AIDS crisis, played a key role in making H.I.V. treatments available in the developing world. (Source: NYT Health)
HIV/AIDS Researchers, Officials En Route To AIDS 2014 Conference Lost In MH17 Crash
The international research community awaits confirmation of their worst fears that scores of colleagues enroute to the International AIDS Conference in Melbourne were among those who perished in the crash of Malaysian Airlines Flight 17. (Source: Forbes.com Healthcare News)
HIV/AIDS Researchers, Officials Perish In Malaysia Airlines MH17 Crash
The international research community awaits confirmation of their worst fears that scores of colleagues enroute to the International AIDS Conference in Melbourne were among those who perished in the crash of Malaysian Airlines Flight 17. (Source: Forbes.com Healthcare News)
100 Leading HIV/AIDS Researchers Killed on Malaysian Jet100 Leading HIV/AIDS Researchers Killed on Malaysian Jet
An estimated 100 of the world's leading HIV/AIDS researchers were among the 298 people killed on a Malaysian passenger jet that was shot down in eastern Ukraine. Medscape Medical News (Source: Medscape Hiv-Aids Headlines)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Changes in HIV Viral Load and CD4 in ART-Naive IndividualsChanges in HIV Viral Load and CD4 in ART-Naive Individuals
What causes short-term changes in HIV viral load and CD4 cell count in ART-naive individuals? AIDS (Source: Medscape Today Headlines)
Minutes silence held for MH17 victims headed to Melbourne AIDS conference
A candlelight vigil has been held in Melbourne in honour of the world's leading experts in the battle against HIV who were killed while travelling on Malaysia Airlines flight MH17 en route to an AIDS conference in the city. (Source: the Mail online | Health)
HIV Health Community Reels from Losses in Malaysia Airlines Tragedy
A top antiviral-therapy researcher, Joep Lange, was among the more than 100 researchers and advocates killed en route to the 20th International AIDS Conference in Australia -- Read more on ScientificAmerican.com (Source: Scientific American - Official RSS Feed)
Africa: Start Early, Start Now - Governments, Health Care Providers and NGOs Urged to Ramp Up Efforts to Meet the Needs of the Youngest Children in HIV-Affected Families
[PR Newswire]Melbourne, Australia -Statement from Kate Iorpenda, Chair of The Coalition for Children Affected by AIDS (Source: AllAfrica News: HIV-Aids and STDs)
IAC: Tragedy, Low Attendance Won't Stop Meeting
(MedPage Today) -- MELBOURNE, Australia -- The 2014 International AIDS Conference will go on as planned, despite the deaths of dozens of delegates aboard the airliner said to have been shot down over eastern Ukraine. (Source: MedPage Today Gastroenterology)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Africa: Get Tested, Get Treated - How Communities and Volunteers Can Play a Key Role in the Fight Against HIV
[IFRC]Millions of men and women around the world volunteer their time to help people living with HIV in their communities. But despite their valuable contribution, community health workers and volunteers often remain invisible, unacknowledged and under-utilised. As world leaders and HIV experts gather in Melbourne, Australia for the upcoming 2014 International AIDS Conference, the delegation from the International Federation of Red Cross and Red Crescent Societies (IFRC) is urging governments to ensure community (Source: AllAfrica News: HIV-Aids and STDs)
MH17 Malaysia Airlines crash: Tributes paid to world-renowned AIDs researcher on board stricken plane
Friends and colleagues of Professor Joep Lange, a world-renown AIDs researcher who was on board the stricken Malaysian flight, paid tribute yesterday to his ?tireless? efforts towards defeating HIV/Aids. (Source: The Independent - Science)
AIDS community mourns as top experts feared killed in downed plane
MELBOURNE/AMSTERDAM (Reuters) - The world of AIDS research was in shock on Friday after dozens of leading HIV experts were feared killed when a Malaysian plane was shot down over Ukraine, fuelling concerns that research on curing the disease could suffer. (Source: Reuters: Health)
Many Sexually Active U.S. Teens Not Tested for HIV: CDC
Only 22 percent of those at risk get screened, and researchers think complacency may be why (Source: Fertility News - Doctors Lounge)
AIDS Activists Stunned by Malaysian Air Crash
MELBOURNE (MedPage Today) -- Many HIV/AIDS researchers and activists were on board Malaysian Airways MH17, the passenger jet that was knocked out of the sky Thursday over Ukraine. (Source: MedPage Today Public Health)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Many Sexually Active U.S. Teens Not Tested for HIV: CDC
Only 22 percent of those at risk get screened, and researchers think complacency may be why Source: HealthDay Related MedlinePlus Pages: HIV/AIDS, Health Screening, Teen Sexual Health (Source: MedlinePlus Health News)
Zambia: National Aids Council Gets New DG
[Times of Zambia]RANKING Zambia as one of the top six countries globally in rapid reduction of new HIV infections is an indication that the nation is poised to win the fight within this generation, National AIDS Council (NAC) board chairperson Joshua Banda has said. (Source: AllAfrica News: HIV-Aids and STDs)
WHO Statement on Mr Glenn Thomas, WHO Media Officer who died in the MH17 plane
It is with deep sadness that we have to inform you that WHO lost one of our colleagues on the Malaysian Airlines crash yesterday. Glenn Thomas from the Department of Communications was travelling to the International AIDS Conference in Australia. His twin sister says he died doing what he loved. Glenn had been with WHO for more than a decade. He came here from the BBC and spent many years providing communications support to the TB Department. Since 2012 he had been working on the media team in DCO, regularly hosting press conferences and working with you at the Palais and with other journalists to promote the work of WHO. Glenn will be remembered for his ready laugh and his passion for public health. (Source: WHO news)
Liberia: In Liberia, One Aids Victim Fighting Through Trauma, Pain
[FrontPageAfrica]Monrovia -As Liberia emerges out of fourteen years of civil conflict, many people still have to live with their own wars, ranging from trauma to sexual gender based violence and from personal wars to family wars. While others are internal and external conflicts to land disputes, etc. But Sue Francis, not her real name, has to fight her own traumatic war that has left her pains and sad memories that is hard to forget but rather live with. "He was the first because he was the general, and in the presence of my father, (Source: AllAfrica News: HIV-Aids and STDs)
New Quality Measures Proposed for Medicare ACO ProgramNew Quality Measures Proposed for Medicare ACO Program
CMS would require organizations to report on 37 quality measures; outcomes and chronic conditions are emphasized. Medscape Medical News (Source: Medscape Hiv-Aids Headlines)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Aids researchers on crashed plane
Dozens of passengers on the Malaysia Airlines plane were thought to have been heading to a major international Aids conference in Australia. (Source: BBC News | Health | UK Edition)
Nigeria: Nigeria Records 35 Percent Reduction in New HIV Infections
[Vanguard]Abuja -United Nations Programme on HIV and AIDS Country Director in Nigeria, Dr. Bilali Camara, has said that a new global report by UNAIDS showed that new HIV infections in Nigeria had declined by 35 per cent in the past three years. (Source: AllAfrica News: HIV-Aids and STDs)
South Africa: 19,000 HIV/Aids Workers Trained for the Frontlines
[IFP]Today the Children with HIV Association (CHIVA) celebrates ten years of mentoring and training healthcare workers to treat HIV/Aids in children and adolescents. (Source: AllAfrica News: HIV-Aids and STDs)
HIV/AIDS field shocked by death of leading researcher in MH17 crash
Joep Lange and at least five others heading to Melbourne meeting were on board downed plane (Source: ScienceNOW)
Rwanda: Deaths From Aids-Related Causes Decline Drastically
[New Times]The United Nations announced Wednesday that Aids-related deaths and new HIV infections fell by over a third in a decade. (Source: AllAfrica News: Health and Medicine)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
MH17 conspiracy theories emerge: Fake passports, AIDS researchers, false flags and more
(NaturalNews) The shooting down of Malaysia Airlines MH17 over Ukraine is a catastrophic event resulting in the loss of 295 lives (280 passengers and 15 crew). Details are still emerging about what really happened, but Netizens are already fronting various theories of what may have... (Source: NaturalNews.com)
Nigeria: New UN Report Indicts Nigeria, Others Over HIV/Aids Increase Amid Global Decline
[This Day]In a new report by the United Nations AIDS (UNAIDS) Thursday in Geneva, Switzerland, Nigeria and two other African countries have been indicted over increasing cases of HIV/AIDS pandemic in their countries amid overall global decline of the disease. (Source: AllAfrica News: HIV-Aids and STDs)
Uganda: HIV Thrives in Fishing Villages
[Observer]A new survey by the Joint Clinical Centre in Kabarole district suggests the HIV/Aids prevalence rate in fishing communities on landing sites has risen. (Source: AllAfrica News: Health and Medicine)
Rwanda: Global Fund Lauds MoH Financial Control System
[New Times]The global Fund to fight Aids, Tuberculosis and Malaria, commonly known as Global Fund, has hailed government for putting in place effective control measures to ensure maximum utilisation of donor funds allocated to the health sector. (Source: AllAfrica News: Health and Medicine)
Causes of death shifting in people with HIV
HIV-positive adults in high income countries face a substantially reduced risk of death from AIDS-related causes, cardiovascular disease, and liver disease compared with a decade ago, according to a large international study. Although deaths from most causes declined over the study period, there was no reduction in death rates from non-AIDS cancers which remained stable over time (1.6 deaths per 1000 years 1999-2000 to 2.1 in 2009-2011). Non-AIDS cancers are now the leading cause of non-AIDS deaths in people with HIV, accounting for 23% of all deaths. (Source: ScienceDaily Headlines)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Prioritizing children and families at AIDS 2014
(Elizabeth Glaser Pediatric AIDS Foundation) Experts from the Elizabeth Glaser Pediatric AIDS Foundation will give oral presentations, moderate conference events, and exhibit a variety of educational posters and abstracts related to ending AIDS in children. (Source: EurekAlert! - Medicine and Health)
Interleukin-10 aids survival of cells transplanted to repair cardiac tissues after MI
(Cell Transplantation Center of Excellence for Aging and Brain Repair) Three groups of rats modeled with a myocardial infarction were treated with smooth muscle cell injections into the MI-damaged area of the heart. One group received unmodified autologous SMCs; another received unmodified allogenic SMCs; the last group received allogenic SMCs modified with interleukin 10 - a small, anti-inflammatory protein. The group receiving allogenic SMCs modified with IL-10 demonstrated cell survival, improved heart function, and protection against the host's rejection of the allogenic SMCs. (Source: EurekAlert! - Medicine and Health)
AIDS Researchers Among Those Feared Dead in Malaysia Flight Crash
Several researchers and participants traveling to a major AIDS conference in Melbourne, Australia were believed to be among the victims of the downing of a Malaysia Airlines flight in Ukraine. (Source: WSJ.com: Health)
Those With HIV Living Longer, International Study Finds
Deaths from AIDS-related causes, heart disease and liver disease have all dropped (Source: WebMD Health)
Non-AIDS Cancers Cause as Many Deaths as AIDS in HIV-Infected Patients (FREE)
By Amy Orciari Herman Edited by André Sofair, MD, MPH, and William E. Chavey, MD, MS Non-AIDS-related cancers are now responsible for as many deaths as AIDS among HIV-infected patients, according to a Lancet study.Researchers followed nearly 50,000 HIV-infected patients receiving ? (Source: Physician's First Watch current issue)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
"Mississippi Baby" Now Has Detectable HIV, Researchers Find
&quot;The child known as the 'Mississippi baby'&mdash;an infant seemingly cured of HIV that was reported as a case study of a prolonged remission of HIV infection in The&nbsp;New England Journal of Medicine last fall&mdash;now has detectable levels of HIV after more than two years of not taking antiretroviral therapy without evidence of virus, according to the pediatric HIV specialist and researchers involved in the case. &quot;'Certainly, this is a disappointing turn of events for this young child, the medical staff involved in the child&rsquo;s care, and the HIV/AIDS research community,' said NIAID Director Anthony S. Fauci, M.D. 'Scientifically, this development reminds us that we still have much more to learn about the intricacies of HIV infection and where the virus hides in the body...
Study Suggests That Low Levels of HIV-1 RNA Detected in the Cerebrospinal Fluid After Up to 10 Years of Suppressive Therapy Are Associated With Local Immune Activation
We examined the frequency and magnitude of persistent low-level HIV-1 RNA in CSF and its relation to the central nervous system (CNS) immune activation. &hellip; &quot;CSF and plasma HIV-1 RNA were measured using the single-copy assay with a detection limit of 0.3 copies/ml in 70 CSF and 68 plasma samples from 45 treated HIV-1-infected patients with less than 40 copies/ml of HIV-1 RNA in both fluids by standard clinical assays. &hellip; &quot;CSF HIV-1 RNA was detected in 12 of the 70 CSF samples (17%) taken after up to 10 years of suppressive therapy, compared to 39 of the 68 plasma samples (57%) with a median concentration of less than 0.3 copies/ml in CSF compared to 0.3 copies/ml in plasma (P&lt;0.0001). &hellip; &quot;Low-level CSF HIV-1 RNA and its association with elevated CSF ne...
Electronic cigarettes are at least as effective as nicotine patches for smoking cessation
Commentary on: Bullen C, Howe C, Laugesen M, et al.. Electronic cigarettes for smoking cessation: a randomised controlled trial. Lancet 2013;382:1629&ndash;37. Context Electronic cigarettes (e-cigarettes) contain refined nicotine dissolved in propylene glycol, glycerine or other humectants, which is vaporised with a battery-powered heating element, activated by suction or manually, and delivered into the airways.1 E-cigarettes have been shown to reduce craving and withdrawal symptoms in abstinent smokers and, as nicotine is delivered without tobacco combustion, are thought to be substantially safer than cigarettes.2 While e-cigarette use is rapidly increasing, relatively little is known about their efficacy for smoking cessation, particularly compared with established nicotine-containing p...
Brief, patient-centred risk-reduction counselling at the time of a rapid HIV test does not affect subsequent acquisition of sexually transmitted infections
Commentary on: Metsch LR, Feaster DJ, Gooden L, et al. Effect of risk-reduction counseling with rapid HIV testing on risk of acquiring sexually transmitted infections: the AWARE randomised clinical trial. JAMA 2013;310:1701&ndash;10. Context HIV testing and counselling (HTC) is a key entry point to care and treatment services for those who test HIV positive, and to prevention services for those who test HIV negative. Over the past few decades, HTC has been scaled up globally through client-initiated and provider-initiated testing services. The WHO recommends counselling as an integral part of all HIV testing strategies: &lsquo;Testing services must be accompanied by appropriate and high-quality pretest information or pretest counselling and post-test counselling&rsquo;.1 However, the natur...
Women with HIV infection on antiretroviral therapy with low viral loads can safely opt for vaginal delivery in the absence of obstetrical risk factors
Commentary on: Briand N, Jasseron C, Sibiude J, et al.. Cesarean section for HIV-infected women in the combination antiretroviral therapies era, 2000&ndash;2010. Am J Obstet Gynecol 2013;209:335e1&ndash;12. Context The risk of mother-to-child HIV transmission (MTCT) is related to the infant's exposure to HIV-infected maternal blood during birth. Studies published in 1999 have shown a protective effect from elective caesarean section (ECS) in reducing the risk of MTCT.1 2 However, these studies were conducted prior to use of combination antiretroviral therapy (cART) in pregnancy becoming widespread. Antiretroviral therapy through maximum suppression of maternal viral load is the most effective means of preventing MTCT.3 Whether there is any additional benefit from ECS for mothers with low v...<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Toward Minimum Standards for Certifying Patient Decision Aids: A Modified Delphi Consensus Process
Conclusions. This study provides preliminary certification criteria for PDAs. Scoring and rating processes need to be tested and finalized. However, the process of appraising the quality of the clinical evidence reported by the PDA should be used to complement these criteria; the proposed standards are designed to rate the quality of the development process and shared decision-making design elements, not the quality of the PDA&rsquo;s clinical content. (Source: Medical Decision Making)
Sample Size and Power When Designing a Randomized Trial for the Estimation of Treatment, Selection, and Preference Effects
Conclusions. With the growing interest in understanding treatment choices and with the use of decision aids, well-designed and adequately powered 2-stage randomized trial designs offer the opportunity to determine the effects of participants&rsquo; preferences. Our sample size formulas will help future studies ensure that they have adequate power to detect selection and preference effects. (Source: Medical Decision Making)
Addressing patients' psychosocial concerns regarding hearing aids within audiology appointments for older adults.
Conclusions: Older adults' psychosocial concerns regarding hearing aids may not always be sufficiently addressed within audiology appointments. A greater emphasis on emotionally-focused communication within audiology could result in improved outcomes from hearing health care services. PMID: 25036799 [PubMed - as supplied by publisher] (Source: American Journal of Audiology)
Active surveillance of adverse events following childhood immunization in Singapore.
CONCLUSIONS: Hospital-based active surveillance can enhance signal detection and follow-up investigations of AEFI. Subsequently, public health bodies are better equipped to maintain public confidence in vaccination programmes and physicians are able to provide relevant advice to parents. It also allows for a better understanding of risk-benefit ratios of specific vaccines and aids the generation of public health vaccination policy. PMID: 25045811 [PubMed - as supplied by publisher] (Source: Vaccine)
Those with HIV Living Longer, International Study Finds
Deaths from AIDS-related causes, heart disease and liver disease have all dropped Source: HealthDay Related MedlinePlus Pages: HIV/AIDS, International Health, Living with HIV/AIDS (Source: MedlinePlus Health News)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Concept Clearance » Monitoring Antiretroviral Adherence to Improve HIV Treatment and Prevention
The aims of this initiative are to improve treatment for HIV/AIDS and HIV prevention by advancing: (i) Methods for real-time or prospective monitoring of oral ARV adherence (antiretroviral therapy [ART], pre-exposure prophylaxis [PrEP]); (ii) Timely and targeted delivery of interventions when adherence monitoring reveals deficits; and, (iii) Predictive models that estimate current risk of viral breakthrough or HIV infection for a given individual based on ART adherence monitoring and related data. (Source: National Institute of Mental Health)
Brown fat found to be at the root of cancer-related wasting syndrome
Many patients with advanced stages of cancer, AIDS, tuberculosis, and other diseases die from a condition called cachexia, which is characterized as a 'wasting' syndrome that causes extreme thinness with muscle weakness. Cachexia is the direct cause of roughly 20 percent of deaths in cancer patients. While boosting food intake doesn't help, and no effective therapies are available, new research points to a promising strategy that may stimulate weight gain and muscle strength. (Source: ScienceDaily Headlines)
AIDS epidemic could be 'wiped out by 2030'
AIDS-related deaths worldwide dropped to 1.5 million last year, from 1.7 million the year before - the sharpest annual decline since the epidemic's peak, the UN says. (Source: the Mail online | Health)
Research on persons with HIV/AIDS not taking medication, not engaged in care
A new study describes factors believed to contribute to the critical public health issues of persons with HIV/AIDS not complying with treatment or care. The study has a particular focus on African American and Latino/Hispanic people with HIV/AIDS, the racial/ethnic groups most affected by HIV/AIDS. (Source: ScienceDaily Headlines)
Community Resistance and Transmitted HIV Drug ResistanceCommunity Resistance and Transmitted HIV Drug Resistance
Could HIV-1 community drug resistance predict the prevalence of transmitted drug resistance? HIV Medicine (Source: Medscape Today Headlines)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Dolutegravir: Clinical Efficacy and Role in HIV TherapyDolutegravir: Clinical Efficacy and Role in HIV Therapy
A comprehensive overview of the integrase-inhibitor dolutegravir, which shows some novel and intriguing characteristics. What's its place in the HIV drug armamentarium? Therapeutic Advances in Chronic Disease (Source: Medscape Today Headlines)
Africa: Factbox - New HIV Infections Fall As Aids Epidemic Stabilises
[AlertNet]London -If the world could rally to end the AIDS epidemic by 2030, 18 million new HIV infections and 11.2 million AIDS-related deaths would be averted, the United Nations said on Wednesday. (Source: AllAfrica News: Health and Medicine)
Africa: Aids Deaths Fall, but Millions Unaware of HIV-Positive Status - UN
[UN News]While showing a downward trend in AIDS-related deaths, a new United Nations report out today warns that19 million of the 35 million people living with the virus globally do not know their HIV-positive status and therefore, ending the AIDS epidemic by 2030 will require smart scale-up to close the gap. (Source: AllAfrica News: Health and Medicine)
Namibia: 73 000 Face ARV Resistance
[Namibian]MORE than 73 000 people on antiretroviral (ARV) therapy in some parts of the country run the risk of becoming drug resistant after they were taken off their prescribed medication because of shortages. (Source: AllAfrica News: HIV-Aids and STDs)
Zimbabwe: Zimbabwe Accounts for Three Per Cent of New Global HIV Infections
[New Zimbabwe]ZIMBABWE is one of 15 countries in the world accounting for 75 percent of new HIV infections worldwide, according to a new report by the United Nations Programme on HIV and AIDS. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Nigeria: Nigeria, S'Africa, Uganda Account for 48 Per Cent New HIV Infections
[Guardian]THE Federal Government's efforts through the National Agency for the Control of AIDS (NACA) notwithstanding, Nigeria is one of the 15 countries accounting for over 75 per cent of the 2.1 million new Human Immuno-deficiency Virus (HIV) infections that occurred in 2013. (Source: AllAfrica News: HIV-Aids and STDs)
AIDS Epidemic May Be Subsiding: Report
Title: AIDS Epidemic May Be Subsiding: ReportCategory: Health NewsCreated: 7/16/2014 1:35:00 PMLast Editorial Review: 7/17/2014 12:00:00 AM (Source: MedicineNet HIV General)
Nigeria: Red Cross, UNAIDS Seek Support to Improve Access to HIV Care
[Guardian]THE International Federation of Red Cross and Red Crescent Societies (IFRC), in collaboration with Joint United Nation Programme on AIDS (UNAIDS), has called on stakeholders in the health sector and partners to join them in the implementation of an intensive Human Immuno-deficiency Virus (HIV)/Acquired Immune Deficiency Syndrome (AIDS) campaign to improve access to service for 2.6 million people in Benue and Cross Rivers states. (Source: AllAfrica News: HIV-Aids and STDs)
NYU research on persons w/ HIV/AIDS not taking medication and not engaged in care
(New York University) The study describes factors believed to contribute to these critical public health issues, with a focus on African American and Latino/Hispanic PLHAs, the racial/ethnic groups most affected by HIV/AIDS. (Source: EurekAlert! - Medicine and Health)
Brown fat found to be at the root of cancer-related wasting syndrome
(Cell Press) Many patients with advanced stages of cancer, AIDS, tuberculosis, and other diseases die from a condition called cachexia, which is characterized as a 'wasting' syndrome that causes extreme thinness with muscle weakness. Cachexia is the direct cause of roughly 20 percent of deaths in cancer patients. While boosting food intake doesn't help, and no effective therapies are available, new research points to a promising strategy that may stimulate weight gain and muscle strength. (Source: EurekAlert! - Cancer)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Biomarker discovery may lead to new HIV treatment
(WHITECOAT STRATEGIES, LLC) Further analysis of a Phase II study of therapeutic HIV vaccine candidate Vacc-4x revealed a potential biomarker associated with participants who experienced a more profound viral load reduction after receiving the vaccine. The results of this exploratory, ad hoc, subset analysis by St George's, University of London and Bionor Pharma were announced today at the AIDS 2014 Conference in Melbourne, Australia. (Source: EurekAlert! - Infectious and Emerging Diseases)
High rates of violence suffered by unstably housed women in San Francisco
(University of California - San Francisco) 'We looked at all types of violence -- physical, sexual and emotional. We expected to find higher rates than those reported in the general population, but we were surprised at the amount of harm inflicted upon this incredibly vulnerable population of women and the multitude of perpetrators,' said study principal investigator, Elise D. Riley, PhD, associate professor of medicine at the UCSF HIV/AIDS Division at San Francisco General Hospital and Trauma Center. (Source: EurekAlert! - Infectious and Emerging Diseases)
Kidney Dysfunction Among HIV-Infected Children in Latin America and the Caribbean
AIDS Research and Human Retroviruses , Vol. 0, No. 0. (Source: AIDS Research and Human Retroviruses)
AIDS Epidemic May Be Subsiding: Report
Number of new infections, deaths declining, while more with HIV getting lifesaving medications (Source: Fertility News - Doctors Lounge)
Sensory hair cell regeneration in the zebrafish lateral line
Abstract Damage or destruction of sensory hair cells in the inner ear leads to hearing or balance deficits that can be debilitating, especially in older adults. Unfortunately, the damage is permanent, as regeneration of the inner ear sensory epithelia does not occur in mammals. Zebrafish and other non?mammalian vertebrates have the remarkable ability to regenerate sensory hair cells and understanding the molecular and cellular basis for this regenerative ability will hopefully aid us in designing therapies to induce regeneration in mammals. Zebrafish not only possess hair cells in the ear but also in the sensory lateral line system. Hair cells in both organs are functionally analogous to hair cells in the inner ear of mammals. The lateral line is a mechanosensory system found in most aqu...<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Sepsis severe or septic shock: outcome according to the immune status and immunodeficiency profile.
Conclusion:immunodeficiency is common in patients with severe sepsis or septic shock. Despite a similar crude mortality, immunodeficiency was associated with an increased risk of short-term mortality after multivariate analysis. Neutropenia and specific, but not all, profiles of immunodeficiency were independently associated with an increased risk of death. Objective: to evaluate the influence of the immune profile on the outcome at day 28 (D28) of patients admitted in ICU for septic shock or severe sepsis. Materials and Methods: we conducted an observational study using a prospective multicenter database, and included all patients admitted in 11 ICUs for severe sepsis or septic shock, from January 1997 to August 2011. Seven profiles of immunodeficiency were defined. The prognostic...
Falls and Use of Assistive Devices in Stroke Patients with Hemiparesis: Association with Balance Ability and Fall Efficacy.
CONCLUSIONS: Stroke patients with fall experience and walking aids might be considered at increased risk of falling. CLINICAL RELEVANCE: Preventive measures for individuals using walking aids may be beneficial in reducing the fall rate of community-dwelling stroke patients. PMID: 25042606 [PubMed - as supplied by publisher] (Source: Rehabilitation Nursing)
Rehabilitation versus Nursing Home Nurses' Low Back and Neck-Shoulder Complaints.
CONCLUSIONS: Differences between the nurse groups as to work tasks might be a reason for differences in musculoskeletal complaints. Further comparisons between nurses working in different fields might reveal more accurate potential risk factors for work-related musculoskeletal complaints. CLINICAL RELEVANCE: Instruction for static/awkward posture avoidance, by using mechanical aids and designing a friendlier environment, should be part of a nursing staff injury prevention strategy. PMID: 25042522 [PubMed - as supplied by publisher] (Source: Rehabilitation Nursing)
Update from Team Himiti!
We moved into the village on the June 28th ready to educate the villagers of Himiti about HIV/AIDS. On the very first day we met our host families and spent the day getting used to our environment. On the second day in the village we were able to introduce ourselves to a church of more than 150 members and we had our first teaching at another church. Throughout the week, while doing the community surveys, we got to explore the landscape of Himiti as we hiked mountains to get to all the sub-villages. The view from high up included the whole village and the hippo lake (Lake Babati). Unfortunately, Grant and Enoch got sick on the third day for two days and became all too acquainted with the well-known Traveler?s Disease. The next day Emily followed suit. This was not a good start for the gr...
Hello from Bonga Village!
Greetings from the SIC volunteers in Bonga Village! Our team, self-proclaimed the Bonga Blue, includes Kimmi, Emily W., Nicko, Zach, Emmy and Hannah Mac. We have been hard at work the past two weeks, as we?ve been reaching out to the many different community and student groups Bonga has to offer. There are two primary and two secondary schools in addition to the three churches, two mosques, and the clinic. Bonga is a busy village where all sorts of people from around the area come to go to market, to seek treatment at the clinic, and to attend school &#8211; as it is where the only two secondary schools are located in the ward. So far, the people have been incredibly receptive to our teachings. We already have two testing days planned for the village, with the first coming up this week a...<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
VP2 Update: Greetings from Haraa!
We get to Haraa by driving up. Not up some and then down some. Just up. We arrived at the top of a mountain that would be our new home for the summer. At first we could not speak while we walked around the village &#8211; the seemingly monstrous hills took our breath while leaving us with only a grunt here and there. The &#8220;shortcuts&#8221; were even worse. Perhaps the translation is off because we thought shortcut meant short and easy! However, in just two weeks we&#8217;ve fallen in love with this place, and everything about it, including our epic hikes to get just about anywhere! What&#8217;s more, each of us has found something of our own in Haraa. Rashidi&#8217;s found his spot as a hot shot on the football (soccer) team &#8211; the guys are probably already trying to recruit him ...
AIDS deaths decline, but not HIV cases
The United Nations has set targets to reduce deaths and new cases of AIDS by 90 percent by 2030, but some health officials say goal is unrealistic (Source: Health News: CBSNews.com)
Vaccination in HIV-Infected Adults
AIDS Patient Care and STDs , Vol. 0, No. 0. (Source: AIDS Patient Care and STDs)
Identification of a Novel HIV-1 Second-Generation Recombinant Form (CRF01_AE/CRF07_BC) in Jilin, China
AIDS Research and Human Retroviruses , Vol. 0, No. 0. (Source: AIDS Research and Human Retroviruses)
Habitual Nutrient Intake in HIV-Infected Youth and Associations with HIV-Related Factors
AIDS Research and Human Retroviruses , Vol. 0, No. 0. (Source: AIDS Research and Human Retroviruses)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
HIV-1 Nef Protein Carries Multiple Epitopes Suitable for Induction of Cellular Immunity for an HIV Vaccine in Africa
AIDS Research and Human Retroviruses , Vol. 0, No. 0. (Source: AIDS Research and Human Retroviruses)
AIDS deaths fall, but millions unaware of HIV-positive status, warns UN report
While showing a downward trend in AIDS-related deaths, a new United Nations report out today warns that19 million of the 35 million people living with the virus globally do not know their HIV-positive status and therefore, ending the AIDS epidemic by 2030 will require smart scale-up to close the gap. (Source: UN News Centre - Health, Poverty, Food Security)
AIDS Epidemic May Be Subsiding: Report
Number of new infections, deaths declining, while more with HIV getting lifesaving medications (Source: WebMD Health)
Tactile Interface Technology for People with Vision Disabilities
Imagine feeling a slimy jellyfish, a prickly cactus or map directions on your iPad mini Retina display, because that?s where tactile technology is headed. But you?ll need more than just an index finger to feel your way around. (Source: Disabled World)
AIDS Epidemic May Be Subsiding
Number of new infections, deaths declining, while more with HIV getting lifesaving medications Source: HealthDay Related MedlinePlus Pages: HIV/AIDS, HIV/AIDS Medicines, International Health (Source: MedlinePlus Health News)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Aids can be 'under control by 2030'
The Aids epidemic can be brought under control by 2030, according to a report by the United Nations Aids agency. (Source: BBC News | Health | UK Edition)
Malawi: Trying to Reach Deaf and Blind Community With HIV Messaging
[GFO]Tailoring outreach to people with disabilities a goal for advocates under NFM (Source: AllAfrica News: HIV-Aids and STDs)
Cote d'Ivoire: Sexual Violence Fuels HIV Epidemic
[Key Correspondents]Three years after the Ivory Coast post-election crisis of 2010 ended, rape is still a major problem and the security situation for Ivorian women remains bleak. (Source: AllAfrica News: HIV-Aids and STDs)
South Africa: Fight Against HIV, TB to Be Intensified in Prisons
[SAnews.gov.za]Pretoria -The Department of Justice and Correctional Services will intensify the fight against HIV and Tuberculosis in prisons, says Minister Michael Masutha. (Source: AllAfrica News: HIV-Aids and STDs)
Zambia: Disabled Needing HIV Services Face Discrimination - Report
[AlertNet]In Zambia, where disability is often considered a punishment inflicted by evil spirits, nearly one million people with disabilities are struggling to access HIV prevention or testing services or treatment, a rights group said. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Global AIDS epidemic can be controlled by 2030, U.N. says
LONDON (Reuters) - New HIV infections and deaths from AIDS are decreasing, the United Nations said on Wednesday, making it possible to control the epidemic by 2030 and eventually end it "in every region, in every country". (Source: Reuters: Health)
Zambia: People With Disabilities Left Behind in HIV Response
[HRW]The nearly two million people with disabilities in Zambia face significant barriers to HIV prevention, testing, and treatment, Human Rights Watch said in a report released today. While the Zambian government has made considerable progress scaling up its response to HIV generally, few programs are accessible to people with disabilities and social stigma prevents their access to HIV services on an equal basis with others. (Source: AllAfrica News: HIV-Aids and STDs)
Zambia: Deaf, and Shut Out from HIV Information
[HRW]Faith learned she was HIV positive two years ago, after giving birth to her daughter. The Zambian government prides itself on its HIV prevention outreach, and every pregnant woman is supposed to be tested for the virus, to prevent passing it on to their babies. But Faith, now 25, is deaf, and was never tested before the baby was born. Nor did she receive even basic information about HIV. (Source: AllAfrica News: HIV-Aids and STDs)
Zimbabwe: Boy, 10, Accidentally Killed Over HIV Meds
[New Zimbabwe]A MATABELELAND South man slapped his HIV positive ten year-old brother after the boy refused to take his medication. The boy however, fell headlong onto a pile of bricks and died, the High Court heard in Bulawayo this week. (Source: AllAfrica News: HIV-Aids and STDs)
Zimbabwe: Ex-Convict Sets Girlfriend Ablaze for 'Infecting' Him With HIV
[New Zimbabwe]AN ex-convict who was released from prison in February this year under the presidential amnesty programme set his girlfriend on fire for allegedly 'infecting' him with HIV. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Uganda: Mississipi Baby 'Cured'of HIV Turns Positive
[Observer]A US toddler who was thought to have been cured from HIV has been found to still harbour the virus. (Source: AllAfrica News: HIV-Aids and STDs)
Uganda: Ugandan Doctor Re-Elected to Global HIV Body
[Observer]Dr Alex Muganzi, a doctor for HIV/Aids patients and head of the Infectious Diseases Institute (IDI) outreach department, has been re-elected to the International Aids Society (IAS) governing council as the Africa representative. (Source: AllAfrica News: Health and Medicine)
Nigeria: Stakeholders Task C'river Govt On Anti-HIV/Aids Campaign
[Independent]Calabar Stakeholders in the fight against the spread of HIV/AIDS in Cross River State want the state government to evolve new ways of funding the campaign against the scourge in the state. (Source: AllAfrica News: HIV-Aids and STDs)
'UK teens unaware of HIV or Aids'
There's a call for better education for 12 to 17-year-olds about how they can catch HIV and Aids. (Source: BBC News | Health | UK Edition)
HIV-2 viral tropism influences CD4+ T cell count regardless of viral load
Conclusions The presence of X4-tropic viruses in HIV-2 infection is associated with low CD4+ cell counts, regardless of antiretroviral treatment. Along with CD4+ cell counts, viral tropism testing may assist decisions about when to initiate antiretroviral therapy in HIV-2-infected individuals. (Source: Journal of Antimicrobial Chemotherapy)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Temporal trends in the discontinuation of first-line antiretroviral therapy
Conclusions Discontinuation rates of first-line therapy have decreased over time, but are still quite high even for the latest drug combinations. In the most recent era, younger women on a PI regimen and those not achieving optimal adherence had the highest risk of discontinuing first-line antiretroviral therapy. (Source: Journal of Antimicrobial Chemotherapy)
This is My Story: participatory performance for HIV and AIDS education at the University of Malawi
Discussion (PACED) method engages artists and people living with HIV and AIDS (PLWHA) to create a performance that encourages community dialog about HIV and AIDS and empowers PLWHA. &lsquo;This is My Story&rsquo; was a program at the University of Malawi, Chancellor College, which adapted the PACED approach for university students. A qualitative evaluation conducted 1 year later among students and PLWHA participants and audience members demonstrated retention of the following themes: (i) trust in a relationship and how it affects women,(ii) equality for PLWHA and (iii) life after HIV and AIDS. All of the PLWHA and 90.9% of student participants reported a greater sense of empowerment. Of the audience members, 82.1% discussed the performance with friends and family. We thus present the PACED...
The effectiveness of HIV/AIDS school-based sexual health education programmes in Nigeria: a systematic review
HIV/AIDS is one of the most important public health challenges facing Nigeria today. Recent evidence has revealed that the adolescent population make up a large proportion of the 3.7% reported prevalence rate among Nigerians aged 15&ndash;49 years. School-based sexual health education has therefore become an important tool towards fighting this problem. This systematic review assesses the efficacy of these educational programmes and examines how future programmes and their evaluations can improve. Primary literature published between January 2002 and May 2012, which measured sexual health outcomes among school-based Nigerians before and after a sexual health education programme was delivered, was identified. All seven studies that met the inclusion and exclusion criteria showed there had b...
Health information technology interventions enhance care completion, engagement in HIV care and treatment, and viral suppression among HIV-infected patients in publicly funded settings.
We examined the effect of six health information technology (HIT) interventions in a Ryan White-funded Special Projects of National Significance (SPNS) on care completion services, engagement in HIV care, and viral suppression. METHODS: Interventions included use of surveillance data to identify out-of-care individuals, extending access to electronic health records to support service providers, use of electronic laboratory ordering and prescribing, and development of a patient portal. Data from a sample of electronic patient records from each site were analyzed to assess changes in utilization of comprehensive care (prevention screening, support service utilization), engagement in primary HIV medical care (receipt of services and use of antiretroviral therapy), and viral suppression. W...
The usefulness of a diagnostic method combining high-resolution CT findings and serum markers for cytomegalovirus pneumonia and pneumocystis pneumonia in non-AIDS patients.
CONCLUSION: The combined use of HRCT findings and serum markers is useful for the diagnosis of CMVP and PCP in non-AIDS patients. The typical HRCT findings for the differential diagnosis included extensive GGA with mosaic pattern in PCP and nodules, nodules with or without the tree-in-bud pattern, and the halo sign in CMVP. PMID: 25031277 [PubMed - as supplied by publisher] (Source: Acta Radiologica)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Microdevices for examining immunological responses of single cells to HIV.
Authors: Choi J, Jeong Y, Lee KH Abstract More than 60 million people in the world have been diagnosed with human immunodeficiency virus (HIV) infections since the virus was recognized as the causative agent of acquired immunodeficiency syndrome (AIDS) in the 1980s. Even though more than half of the infected patients have died, effective disease treatment and prevention measures have not been established. Antiretroviral therapy is the only proven HIV treatment which sustains suppression of patient viremia. Current routine approaches to treat HIV infections are targeted at developing vaccines that will induce humoral or cell memory immune responses. However, developing an effective vaccine has been challenging because the HIV mutates rapidly, which allows the virus to evade immune s...
Sierra Leone: Treating Children with Malaria
Pediatrician Leo Ho worked in the intensive care unit of the MSF-run Gondama Hospital in the Bo region of Sierra Leone in 2007. During his assignment, Dr. Ho was continually treating the most severe malaria cases: children brought to the hospital who had already fallen into a coma; those who were severely malnourished; or also suffering from tuberculosis or HIV/AIDS. ?We were just trying to keep them alive,? says Dr. Ho. (Source: MSF News)
Americans With AIDS Should Be Screened for CryptococcusAmericans With AIDS Should Be Screened for Cryptococcus
A CDC study has suggested that 2.9% of Americans with advanced AIDS were positive for cryptococcal antigen between 1986 and 2012; screening could decrease mortality and costs. Medscape Medical News (Source: Medscape Medical News Headlines)
Sexual Orientation and Health Among U.S. Adults: National Health Interview Survey, 2013
NHIS is an annual multipurpose health survey conducted continuously throughout the year. Analyses were based on data collected in 2013 from 34,557 adults aged 18 and over. Sampling weights were used to produce national estimates that are representative of the civilian non-institutionalized U.S. adult population. Differences in health-related behaviors, health status, health care service utilization, and health care access by sexual orientation were examined for adults aged 18?64, and separately for men and women. (Source: CDC HIV/AIDS Prevention)
DRC: Renewed Violence in Baraka, South Kivu
Renewed fighting erupted in the beginning of November in Baraka, South Kivu Province, in northeastern Democratic Republic of Congo. In Baraka, MSF is supporting a general hospital and treating tuberculosis, HIV/AIDS, and cholera, as well as running a nutrition project and providing reproductive health care. As MSF head of mission for South Kivu, Goedele Van Bavel, explains in this audio slide show, MSF is currently balancing whether to evacuate its operations in light of the recent developments. (Source: MSF News)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Africa: Investment Needed for Health and Human Rights of People Who Inject Drugs
[Key Correspondents]People who inject drugs remain one of the highest-risk groups for contracting HIV, but infringements of their human rights around the world threatens to derail progress on ending AIDS. (Source: AllAfrica News: Health and Medicine)
Social Determinants of Health among Adults with Diagnosed HIV Infection in 20 States, the District of Columbia, and Puerto Rico, 2010
The report will focus on census tract-level social determinants of health (SDH) among adults with HIV infection diagnosed in 2010 in 20 U.S. states, the District of Columbia, and Puerto Rico. The report will present national HIV surveillance data and SDH in various stratifications by race/ethnicity, sex, age, and transmission category. The SDH variables examined are: % of the population living below federal poverty, % of population with less than high school diploma, median household income, and % of population unemployed. (Source: CDC HIV/AIDS Prevention)
HIV/AIDS Data through December 2011: Provided for the Ryan White HIV/AIDS Treatment Extension Act of 2009, for Fiscal Year 2013
The report describes how HIV surveillance data are used for funding Ryan White HIV/AIDS programs. (Source: CDC HIV/AIDS Prevention)
Africa: Could HIV Self-Testing Be a Game Changer in Africa?
[AlertNet]London -In Africa, where fewer than half the people know their HIV status, HIV self-testing is being explored as a way of encouraging more individuals, particularly in high risk groups, to know their status as a first step to seeking treatment, an AIDS charity said on Monday. (Source: AllAfrica News: Health and Medicine)
Kenya: Govt, NGOs Partnership Supports Fight Against HIV, Disease
[CAJ News]Nairobi -GOVERNMENT welcomed its partnership with the Global Fund to Fight AIDS, Tuberculosis and Malaria and Kenya Red Cross. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Uganda: Ruling Against LGBT Activists Sets Dangerous Precedent
[HRW]Nairobi -The decision of the Ugandan High Court published on July 9, 2014, endorsing the government closure of a lesbian, gay, bisexual and transgender (LGBT) rights workshop violates the right to freedom of assembly, Human Rights Watch said today. (Source: AllAfrica News: HIV-Aids and STDs)
Namibia: Ministry Scales Up Circumcision Drive
[New Era]The Zambezi Region has the highest HIV prevalence rate in the country, compounded by male residents' reluctance to get circumcised. (Source: AllAfrica News: HIV-Aids and STDs)
HIV: 'the WHO is perpetuating gay stereotypes'
The World Health Organisation has recommended that all gay men take antiretroviral drugs to stop the spread of HIV, but surely education - not more drugs - is the answer (Source: Telegraph Health)
Zambia: Sex Industry Demand for Unsafe Sex Hampers Fight Against HIV
[Key Correspondents]A Zambian sex worker living with HIV says efforts to reduce new HIV infections are being hampered by demand for unprotected sex, which comes at a higher price. (Source: AllAfrica News: HIV-Aids and STDs)
Kenya: Community and Clergy Urged to Support Needle Exchange Services
[AlertNet]Community and religious groups are failing to support needle exchange services for drug users in Kenya, despite government efforts to provide clean needles and reduce the spread of HIV. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Serum-Based Assay Accurately Detects Single Nucleotide Polymorphisms of IL28B and SOCS3 in HIV/Hepatitis C Virus-Coinfected Subjects
AIDS Research and Human Retroviruses , Vol. 0, No. 0. (Source: AIDS Research and Human Retroviruses)
Highlights from this issue
Having just returned from the Centers for Disease Control and American Sexually Transmitted Diseases Association (ASTDA) conference in Atlanta, I&rsquo;m struck by the speed of technological change in how we collect, handle and use data. Many presentations addressed novel means of surveillance, and indeed addressed a wider variety of potential influences on sexual health than we usually consider&mdash;for example, housing, and local crime rates. Secret diaries are no longer in the form of a the handwritten scrawl of Adrian Mole aged 13&mdash;we now ask research subjects and to entrust us with online records of their sexual life. In this issue Stalgaitis and Glick1 report a systematic review of the use of web-based diaries in sexual risk behaviour research, reflecting on their use, methodol...
How important is confidentiality in sexual health clinics? A survey of patients across 51 clinics in England
Introduction Confidentiality has been the bedrock of sexually transmitted infection (STI) clinics in the UK since the Venereal Diseases Act 1917,1 which has been updated with each reorganisation of the NHS within England.2 Anyone attending a STI clinic is ensured confidentiality and anonymity beyond that routinely provided within the NHS by having separate registration systems, and separate case notes or electronic patient records, from other health service records. Investigations are ordered using a clinic number, not the person's name, and there is no routine communication with general practitioners (GP). Patients are also under no obligation to provide their real name. This additional confidentiality is very important to some. Of school attendees aged 13&ndash;14&nbsp;years, 56.3% rated...
HPTN 035 phase II/IIb randomised safety and effectiveness study of the vaginal microbicides BufferGel and 0.5% PRO 2000 for the prevention of sexually transmitted infections in women
Conclusions The incidence of STIs was high during HIV Prevention Trials Network 035 despite provision of free condoms and comprehensive risk-reduction counselling, highlighting the need for effective STI prevention programmes in this population. Unfortunately, candidate microbicides BufferGel and PRO2000 had no protective effect against gonorrhoea, chlamydia or trichomoniasis. Trial registration number NCT00074425. (Source: Sexually Transmitted Infections)
The use of web-based diaries in sexual risk behaviour research: a systematic review
Conclusions Web-based diaries are an effective means of studying sexual risk behaviour. More uniform reporting and further research on the extent of reactivity are needed. (Source: Sexually Transmitted Infections)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Systematic review and meta-analysis of HIV prevalence among men in militaries in low income and middle income countries
Conclusions Our data reveals that across the different settings, the burden of HIV among militaries may be higher or lower than the civilian male populations. In this study, male military populations in sub-Saharan Africa, low-income countries and longer-serving men have significantly higher HIV prevalence. Given the national security implications of the increased burden of HIV, interventions targeting military personnel in these populations should be scaled up where appropriate. (Source: Sexually Transmitted Infections)
A peer-led, community-based rapid HIV testing intervention among untested men who have sex with men in China: an operational model for expansion of HIV testing and linkage to care
Conclusions Trained peers providing rapid HIV testing with social support and case management through the early period following diagnosis can efficiently expand HIV testing and improve linkage to care among MSM in China. (Source: Sexually Transmitted Infections)
Reliance on condoms for contraceptive protection among HIV care and treatment clients: a mixed methods study on contraceptive choice and motivation within a generalised epidemic
Conclusions Fears of reinfection prevailed over consideration of pregnancy risk. Given current evidence on reinfection, HCTx services must move beyond a narrow focus on condom promotion, particularly for those in seroconcordant relationships, and consider diverse strategies to meet reproductive needs. (Source: Sexually Transmitted Infections)
Men seeking sex online practise riskier sexual behaviours than men frequenting brothels: survey findings from Singapore
Conclusions Men seeking sex online should receive sexually transmitted infection (STI)/HIV prevention interventions that deal with the factors associated with condom use. (Source: Sexually Transmitted Infections)
Decisions, decisions: the importance of condom use decision making among HIV sero-discordant couples in a prospective cohort study in Uganda
Conclusions Couples who disagreed on decision making, or agreed that one partner decides alone, had significantly lower odds of reporting condom use compared with couples who decided together. HIV counselling interventions that encourage joint sexual decision making may improve condom use within this population. (Source: Sexually Transmitted Infections)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Identifying recently acquired HIV infections among newly diagnosed men who have sex with men attending STI clinics in The Netherlands
Conclusions The proportion of RIs was comparable to studies in similar settings in Europe. Implementation of the RITA for routine surveillance in The Netherlands to assess trends in RIs over time, to study the infections in other groups and to inform public health actions, is being planned. (Source: Sexually Transmitted Infections)
Suboptimal plasma HIV-1 RNA suppression and adherence among sex workers who use illicit drugs in a Canadian setting: an observational cohort study
Conclusions Evidence-based interventions to improve adherence to ART among SW-DU are urgently needed to help produce the maximum HIV treatment and prevention benefit of ART among this highly vulnerable population. (Source: Sexually Transmitted Infections)
The dual impact of antiretroviral therapy and sexual behaviour changes on HIV epidemiologic trends in Uganda: a modelling study
Conclusions HIV prevalence will rise. Even small increases in partner turnover rates will lead to an additional substantial increase in HIV prevalence. Policy makers are urged to continue HIV prevention activities, including promoting sex education, and to be prepared for a higher than previously suggested number of HIV infected people in need of treatment. (Source: Sexually Transmitted Infections)
HIV treatment cascade among transgender women in a San Francisco respondent driven sampling study
Conclusions We observed a high prevalence of HIV in our population-based estimates of transwomen in San Francisco, coupled with modest ART use and low virological suppression rates, indicating high potential for forward transmission. Poor HIV treatment outcomes were consistently associated with housing instability. These data suggest that multi-level efforts, including efforts to address housing insecurity, are urgently needed to ameliorate disparities in HIV clinical outcomes among transwomen and reduce secondary HIV transmission to their partners. (Source: Sexually Transmitted Infections)
Cerebral microsporidiosis manifesting as progressive multifocal leukoencephalopathy in an HIV-infected individual - a case report
This report underscores the need for physicians to consider microsporidiosis (potentially affecting the brain) when no other etiology is established both in HIV, non-HIV immunosuppressed patients and in immunocompetent individuals. (Source: AIDS Research and Therapy)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Preparation of ?-D glucan nanoparticles and its antifungal activity.
Authors: Anusuya S, Sathiyabama M Abstract This work demonstrates the preparation of ?-D-glucan (isolated from the cell wall of Pythium aphanidermatum) nanoparticles through the addition of 2% (w/v) sodium hydroxide to ?-D glucan solution with constant stirring at 90° C. Addition of sodium tripolyphosphate (TPP) aids the stable formation of nanoparticles. Fourier transform infrared (FTIR) spectroscopy confirmed phosphoric groups of TPP linked with OH group of ?-D-glucan in the nanoparticles. The formation of nanoparticles was observed by the peak at 386nm using UV- visible spectroscopy. The average size of nanoparticle as determined by Zetasizer was about 60nm, while the zeta potential was negative. Scanning electron microscope image showed spherical, smooth and almost homogeno...
Contributions of cell growth and biochemical reactions to nongenetic variability of cells.
This article offers a widely-applicable theory on the influence of biochemical reactions and cellular growth on the phenotypic variability of growing, isogenic cells. The theory aids the design and interpretation of experiments involving single-molecule counting or real-time imaging of fluorescent reporter constructs. PMID: 25028872 [PubMed - in process] (Source: Biophysical Journal)
Reactions: AIDS 'Cures,' Sharing Therapy Notes, Examining the Physical Exam
Letters to the editor and online comments. (Source: NYT Health)
Prevalence of HIV-1 Transmitted Drug Resistance in Liberia
AIDS Research and Human Retroviruses , Vol. 0, No. 0. (Source: AIDS Research and Human Retroviruses)
Nigeria: Nigeria Has Largest Aids Project in the World - USAID Director
[Daily Trust]Mission Director, of the United States Agency for International Development (USAID), Michael Harvey has said that Nigeria has the largest AIDs project of the agency, in the world. He said so today at the End of Project Dissemination of the Community Based Support (CUBS) for Orphans and Vulnerable Children which took place at the Yar'Adua Centre, Abuja. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Yerkes team receives HIV grant
AmfAR, the Foundation for AIDS Research gave $180,000 to a research team at Yerkes National Primate Research Center. The group, led by Dr. Guido Silvestri on the campus of Emory University, will study non-human primates infected with simian immunodeficiency virus (SIV), which closely mimics HIV in humans. They are analyzing SIV-infected non-human primates in hopes of learning how ?the Berlin patient,? an HIV-positive man with leukemia, was cured of HIV six years ago by receiving a stem cell? (Source: bizjournals.com Health Care:Biotechnology headlines)
Discharge, TSS, and E.coli Response to Rainfall Events in Urban, Suburban, and Rural Watersheds
Environ. Sci.: Processes Impacts, 2014, Accepted ManuscriptDOI: 10.1039/C4EM00327F, PaperHuajin Chen, Heejun ChangUnderstanding dominant processes influencing microorganism responses to storm events aids in the development of effective management controls on pathogen contamination in surface water so that they are suitable for water...The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - J. Environ. Monit. latest articles)
Traumatic revictimization of men who have sex with men living with HIV/AIDS - Pantalone DW, Horvath KJ, Hart TA, Valentine SE, Kaysen DL.
Abuse in childhood has been established as a predictor of adult abuse, with the strongest associations found between childhood sexual abuse (CSA) and adult sexual victimization. Revictimization has been demonstrated among women, and there is a growing lite... (Source: SafetyLit: All (Unduplicated))
Nigeria: BSN Joins War Against HIV/Aids
[Independent]Lagos -The General Secretary, Bible Society of Nigeria, Rev. Dare Ajiboye, has said that part of the primary duties of the organisation are Bible translation and distribution to Nigerians in an affordable manner. (Source: AllAfrica News: HIV-Aids and STDs)
Kenya: Can the HIV Prevention Pill Work in Kenya?
[The Star]In the 30 years since Aids was identified as a disease, nearly 30 million people have died and another 35 million are currently infected with HIV worldwide. (Source: AllAfrica News: Health and Medicine)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Malawi: Only 30 000 Children Living With HIV Receive Care and Treatment
[Malawi News Agency]Salima -Only 30 000 out of the 180 000 children living with HIV in the country are receiving care and treatment, head of Baylor College of Medicine HIV program Dr. Saeed Ahmed has disclosed. (Source: AllAfrica News: HIV-Aids and STDs)
Kenya: Sex Workers At High Risk of HIV Due to Poor Funding.
[The Star]The government is being urged to put more funding on HIV projects especially those targeting sex workers. Activist Peninah Mwangi says donor funding on these projects has reduced significantly and the government should allocate money to buy condoms, testing kits and create awareness. (Source: AllAfrica News: HIV-Aids and STDs)
HRSA: Clarifications Regarding the Ryan White HIV/AIDS Program and Reconciliation of Advanced Premium Tax Credits Under the Affordable Care Act; Request for Comment
HRSA's HIV/AIDS Bureau is seeking comments on a recently released clarification to a policy which requires Ryan White HIV/AIDS Program grantees and subgrantees that use program funds to purchase health insurance through the Marketplace to pursue any excess premium tax credit a client receives from the IRS upon submission of the client's tax return. (Source: Federal Register updates via the Rural Assistance Center)
Nanoparticle-Spiked Drink Aids Intestinal Imaging In Mice
Micellar naphthalocyanine dye particles let researchers use photoacoustic imaging to spy on tough-to-see sections of the gut (Source: NanoFocus)
Kenya: Over 200 New Cases of HIV Victims
[The Star]There are 214, 000 new cases for sex workers who are HIV positive. Sex workers rights activist Peninah Mwangi says both the national and county governments must both come up with specific programmes for supporting sex workers especially in creating awareness and provision of free condoms (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Multiple Macroenzymes in a Patient With AIDS: Diagnosis Using Ultrafiltration.
CONCLUSIONS: A previous report shows that in cases of excess immunoglobulin, PEG coprecipitates monomeric enzymes along with serum globulins, causing false-positive reporting of macroenzymes. This may explain the discrepancy between PEG and UF results in the presence of hypergammaglobulinemia, making UF a better method of detection in these circumstances. PMID: 25015871 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Cuomo's Plan for HIV Drug Draws Critics
Truvada, a medication that can help prevent HIV in healthy individuals, is gaining favor with government officials, including New York Gov. Andrew Cuomo, but some AIDS activists are opposed to its use. (Source: WSJ.com: Health)
Cross-sectional study of the characteristics, healthcare usage, morbidity and mortality of injecting drug users attending an inner city emergency department
Conclusions Our study characterises the emergency presentations of active IDUs. We describe considerable acute and chronic medical consequences and high healthcare utilisation associated with IDU. This study is of particular relevance to any institution that provides acute medical care to this group of patients. (Source: Emergency Medicine Journal)
Elevated Intraindividual Variability in methamphetamine dependence is associated With poorer everyday functioning
(Source: Psychiatry Research)
Associated changes in the transcription levels of IL-17A and tight junction-associated genes in the duodenal mucosa of rhesus macaques repeatedly exposed to simian/human immunodeficiency virus.
CONCLUSIONS: Acute SHIV, and by extension HIV infection could affect the expression of TJ-associated genes, probably through IL-17A and other immune alterations. PMID: 25034324 [PubMed - as supplied by publisher] (Source: Experimental and Molecular Pathology)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
A Universal Decision Support System: Addressing the Decision Making Needs of Patients, Families, and Clinicians in the Setting of Critical Illness.
Authors: Cox CE, White DB, Abernethy AP Abstract In the setting of a complex critical illness, preference-sensitive decision making-choosing between two or more reasonable treatment options-can be difficult for patients, families, and clinicians alike. A common challenge to making high-quality decisions in this setting is a lack of critical information access and sharing among participants. Decision aids-brochures, web applications, and videos-are a major focus of current research because mounting evidence suggests they can improve decision making quality and enhance collaborative shared decision making. However, many decision aids have important limitations including a relatively narrow capacity for personalization, an inability to gather and generate clinical data, a focus on onl...
Methodology Review: Using Dual-Energy X-ray Absorptiometry (DXA) for the Assessment of Body Composition in Athletes and Active People.
Authors: Nana A, Slater GJ, Stewart AD, Burke LM Abstract Dual energy X-ray absorptiometry (DXA) is rapidly becoming more accessible and popular as a technique to monitor body composition, especially in athletic populations. Although studies in sedentary populations have investigated the validity of DXA assessment of body composition, few studies have examined the issues of reliability in athletic populations and most studies which involve DXA measurements of body composition provide little information on their scanning protocols. This review presents a summary of the sources of error and variability in the measurement of body composition by DXA, and develops a theoretical model of best practice to standardise the conduct and analysis of a DXA scan. Components of this protocol incl...
Signaling of Chloroquine-induced stress in the yeast Saccharomyces cerevisiae requires the Hog1 and Slt2 MAPK Pathways.
Authors: Baranwal S, Azad GK, Singh V, Tomar RS Abstract Chloroquine (CQ) is under clinical use for several decades yet, little is known about CQ sensing and signaling mechanisms or about their impact on various biological pathways. We employed budding yeast Saccharomyces cerevisiae as a model organism to study the pathways targeted by CQ. Our screening with yeast mutants revealed that it targets histone proteins and histone deacetylases (HDACs). Here, we also describe the novel role of mitogen-activated protein kinase Hog1 and Slt2 that aids in survival in the presence of CQ. Cells deficient in Hog1 or Slt2 are found to be CQ hypersensitive and both proteins were phosphorylated in response to CQ exposure. CQ-activated Hog1p is translocated to nucleus and facilitates the expression...
The Prevalence and Incidence of Epiretinal Membranes in Eyes With Inactive Extramacular CMV Retinitis [Retina]
Conclusions. A history of extramacular CMV retinitis is associated with increased prevalence and incidence of ERM formation compared to what is seen in eyes without ocular opportunistic infections in AIDS patients. (Source: Investigative Ophthalmology)
Relationships between familial HIV/AIDS and symptoms of anxiety and depression: the mediating effect of bullying victimization in a prospective sample of South African children and adolescents - Boyes ME, Cluver LD.
South African children and adolescents living in HIV/AIDS-affected families are at elevated risk of both symptoms of anxiety and depressive symptoms. Poverty and HIV/AIDS-related stigma are additional risk factors for these negative mental health outcomes.... (Source: SafetyLit: All (Unduplicated))<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Traumatic revictimization of men who have sex with men living with HIV/AIDS - Pantalone DW, Horvath KJ, Hart TA, Valentine SE, Kaysen DL.
Abuse in childhood has been established as a predictor of adult abuse, with the strongest associations found between childhood sexual abuse (CSA) and adult sexual victimization. Revictimization has been demonstrated among women, and there is a growing lite... (Source: SafetyLit: All (Unduplicated))
Malawi: Empower Women Economically to Eradicate Gender Based Violence and HIV/Aids
[Malawi News Agency]Blantyre -The World University Service of Canada (WUSC) said empowering women economically can help to reduce gender based violence and minimize further spread of HIV and Aids as women would meet their daily needs to reduce their vulnerability. (Source: AllAfrica News: Health and Medicine)
The effects of opioids on HIV reactivation in latently-infected T-lymphoblasts.
CONCLUSIONS: Opioids reactivate HIV in vitro but at concentrations that are far above the plasma levels of analgesic regimes or drug concentrations found in IDUs. HIV reactivation was mediated by effects unrelated to opioid-receptor activation and was tightly linked to the cytotoxic activity of the substances at millimolar concentrations, suggesting that opioid-mediated reactivation of HIV was due to accompanying effects of cellular necrosis such as activation of reactive oxygen species and NF-?B. PMID: 25013451 [PubMed] (Source: AIDS Research and Therapy)
German cohort of HCV mono-infected and HCV/HIV co-infected patients reveals relative under-treatment of co-infected patients.
CONCLUSION: Overall, treatment was only initiated in half of the patients of the entire cohort and in an even smaller proportion of HCV/HIV co-infected patients despite comparable outcome (SVR) and similar baseline characteristics. In the light of newer treatment options, greater efforts to remove the barriers to treatment that still exist for a great proportion of patients especially with HIV/HCV co-infection have to be undertaken. PMID: 25006340 [PubMed] (Source: AIDS Research and Therapy)
Mononuclear Phagocyte Accumulation in Visceral Tissue in HIV Encephalitis: Evidence for Increased Monocyte/Macrophage Trafficking and Altered Differentiation.
Authors: Fischer T, Wyatt CM, D'Agati VD, Croul S, McCourt L, Morgello S, Rappaport J Abstract The invasion of circulating monocytes/macrophages (M?)s from the peripheral blood into the central nervous system (CNS) appears to play an important role in the pathogenesis of HIV dementia (HIV-D), the most severe form of HIV-associated neurocognitive disorders (HAND), often confirmed histologically as HIV encephalitis (HIVE). In order to determine if trafficking of monocytes/M?s is exclusive to the CNS or if it also occurs in organs outside of the brain, we have focused our investigation on visceral tissues of patients with HIVE. Liver, lymph node, spleen, and kidney autopsy tissues from the same HIVE cases investigated in earlier studies were examined by immunohistochemistry for the ...<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
The Antiretroviral Therapy Cohort Collaboration (ART-CC). Durability of first ART regimen and risk factors for modification, interruption or death in HIV-positive patients starting ART in Europe and North America 2002?2009: Erratum
No abstract available (Source: AIDS)
Genome-wide analysis of histone modifications in latently HIV-1 infected T cells
Conclusion:The transcriptional regulation by epigenetic memory should play a key role in the evolution and maintenance of HIV-1 latency accompanied by modulation of signalling molecules in the host cells. (Source: AIDS)
HIV 'cure' won't work until virus eliminated from body
A baby in Mississippi reported free of HIV has relapsed &ndash; showing that even traces of the virus can rebound (Source: New Scientist - HIV and AIDS)
Interventions to improve hearing aid use in adult auditory rehabilitation.
CONCLUSIONS: There is some low to very low quality evidence to support the use of self management support and complex interventions combining self management support and delivery system design in adult auditory rehabilitation. However, effect sizes are small and the range of interventions that have been tested is relatively limited. Priorities for future research should be assessment of long-term outcome a year or more after the intervention, development of a core outcome set for adult auditory rehabilitation and development of study designs and outcome measures that are powered to detect incremental effects of rehabilitative healthcare system changes over and above the provision of a hearing aid. PMID: 25019297 [PubMed - as supplied by publisher] (Source: Cochrane Database of Systemat...
WHO says 'Gay men should take AIDS drugs - even if they're not infected'
This approach is known as pre-exposure prophylaxis or PrEP and is way for at-risk groups protect themselves by taking a single pill, claims the Geneva-based organisation. (Source: the Mail online | Health)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Global Progress on HIV Threatened: WHOGlobal Progress on HIV Threatened: WHO
People most at risk for HIV infection are not getting the health services they need, the World Health Organization (WHO) warns. Medscape Medical News (Source: Medscape Medical News Headlines)
Latest HIV Cure Data Expected at AIDS 2014, More Hep C NewsLatest HIV Cure Data Expected at AIDS 2014, More Hep C News
Scientists and policy makers will gather next week at the largest global HIV meeting, where trial results for TURQUOISE-1 and PHOTO-2 will be presented. Medscape Medical News (Source: Medscape Medical News Headlines)
No end yet in sight for scourge: Setback to Aids battle as child tests positive again
A four-year-old child who was said last year to have been cured of Aids after radical treatment with anti-viral drugs within hours of its birth has been found to be HIV positive ? shattering the hopes that the virus could be vanquished. (Source: The Independent - Science)
Doctors' hopes for radical cure are 'shattered' as a child treated for AIDS is now found to be HIV positive
A four-year-old child who was said last year to have been cured of AIDs after radical treatment with anti-viral drugs within hours of its birth has been found to be HIV positive ? shattering the hopes that the virus could be vanquished. (Source: The Independent - Science)
No end yet in sight for scourge: Setback to Aids battle as child tests positive again
A four-year-old child who was said last year to have been cured of AIDs after radical treatment with anti-viral drugs within hours of its birth has been found to be HIV positive ? shattering the hopes that the virus could be vanquished. (Source: The Independent - Science)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
HIV Signs in Child Hoped to Be Cured
A Mississippi child born with the AIDS virus who scientists thought might have been cured following drug treatment has shown signs of infection again. (Source: WSJ.com: Health)
20th International AIDS Conference20th International AIDS Conference
Read clinically focused news coverage of key developments from AIDS 2014. Medscape HIV/AIDS (Source: Medscape Hiv-Aids Headlines)
If Big Pharma Ignores Antibacterial R&D, Where Will We Get The Drugs To Treat Superbugs?
What is needed is more basic research on bacterial drug resistance. This is where the NIH can play a big role. The total 2014 NIH budget for infectious diseases is $5 billion. However, this is spread across all infectious diseases like HIV/AIDS, as well as biodefense work. Perhaps the time has come for the NIH to make understanding the mechanisms of bacterial resistance a national health priority and invest accordingly. (Source: Forbes.com Healthcare News)
Africa: TB Drug Resistance Signifies Failure
[IRIN]London -Tuberculosis control programmes are among the oldest public health campaigns (dating back 125 years) but are not nearly as successful as they should be. Despite effective drugs having been available for over 50 years, TB still kills a million people a year, making it the world's single deadliest infectious disease after AIDS. (Source: AllAfrica News: Health and Medicine)
Sex differences in benzodiazepine use in the HIV-infected population
(Source: AIDS Care)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
An assessment of health-care students' attitudes toward patients with or at high risk for HIV: implications for education and cultural competency
(Source: AIDS Care)
Perceptions of barriers and facilitators to cervical cancer screening among low-income, HIV-infected women from an integrated HIV clinic
(Source: AIDS Care)
Health care students' reactions towards HIV patients: examining prejudice, emotions, attribution of blame and willingness to interact with HIV/AIDS patients
(Source: AIDS Care)
Motivational barriers to retention of at-risk young adults in HIV-prevention interventions: perceived pressure and efficacy
(Source: AIDS Care)
Lost-to-care and engaged-in-care HIV patients in Leningrad Oblast, Russian Federation: barriers and facilitators to medical visit retention
(Source: AIDS Care)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Sex differentials in the uptake of antiretroviral treatment in Zambia
(Source: AIDS Care)
Covariates of condom use in South Africa: findings from a national population-based survey in 2008
(Source: AIDS Care)
An examination of the HIV serostatus disclosure process among Haitian immigrants in New York City
(Source: AIDS Care)
Dynamic social support networks of younger black men who have sex with men with new HIV infection
(Source: AIDS Care)
My intention was a child but I was very afraid: fertility intentions and HIV risk perceptions among HIV-serodiscordant couples experiencing pregnancy in Kenya
(Source: AIDS Care)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Alcohol use and its association with HIV risk behaviors among a cohort of patients attending HIV clinical care in Tanzania, Kenya, and Namibia
(Source: AIDS Care)
Attitudes toward, and interest in, the test-and-treat strategy for HIV prevention among Thai men who have sex with men
(Source: AIDS Care)
Associations of unprotected anal intercourse with Grindr-met partners among Grindr-using young men who have sex with men in Los Angeles
(Source: AIDS Care)
Community-based electronic data collections for HIV prevention research with black/African-American men in the rural, Southern USA
(Source: AIDS Care)
Development of an electronic medical record-based algorithm to identify patients with unknown HIV status
(Source: AIDS Care)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Tanzania: Quality ARVs Available Nationwide, Aids Body Assures
[Daily News]TANZANIA Commission for AIDS (TACAIDS) yesterday assured availability of anti-retroviral drugs (ARVs), maintaining that quality ARVs are available across the country. (Source: AllAfrica News: HIV-Aids and STDs)
WHO: People most at risk of HIV are not getting the health services they need
Failure to provide adequate HIV services for key groups ? men who have sex with men, people in prison, people who inject drugs, sex workers and transgender people ? threatens global progress on the HIV response, warns WHO. These people are most at risk of HIV infection yet are least likely to have access to HIV prevention, testing and treatment services. In many countries they are left out of national HIV plans, and discriminatory laws and policies are major barriers to access. (Source: WHO news)
Doctors devastated after HIV virus reappears in toddler believed to have been cured
As recently as March, doctors had said that the 4-year-old Mississippi girl seemed free of HIV despite not having been on AIDS drugs for about two years, which was a medical first. (Source: the Mail online | Health)
Key high-risk HIV groups threaten AIDS progress, warns the WHO
GENEVA/LONDON - Five key groups, including gay men, prostitutes and prisoners, have stubbornly high rates of HIV that are threatening progress in the global AIDS battle, the World Health Organisation (WHO) said on Friday. (Source: Reuters: Health)
Prevalence and Correlates of Cryptococcal Antigen Positivity Among AIDS Patients ? United States, 1986?2012
(Source: CDC Morbidity and Mortality Weekly Report)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Migrant children used as human pawns to spread infectious disease across America, warn netizens
(NaturalNews) America is in a de facto state of invasion, and it's an invasion that was deliberately engineered to "occupy" America with a flood of illegal immigrants known to be carriers of tuberculosis, scabies, lice, AIDS, Swine Flu and other infectious diseases, warn netizens... (Source: NaturalNews.com)
Malawi: Discrimination Makes Women Vulnerable to HIV
[Malawi News Agency]Lack of economic opportunities, low educational levels, social and political discrimination influences the vulnerability of women to HIV. (Source: AllAfrica News: HIV-Aids and STDs)
Phylogenetic Analysis of HIV Type 1 CRF02_AG in Multiple Genes in Italian and African Patients Living in Italy
AIDS Research and Human Retroviruses , Vol. 0, No. 0. (Source: AIDS Research and Human Retroviruses)
HIV 'cure' girl still has virus
Mississippi child was previously thought to have been cleared of infection by powerful doses of medication after birth Continue reading... (Source: Guardian Unlimited Science)
[Perspective] A fitness bottleneck in HIV-1 transmission
A successful infection is determined in part by how close a viral genome is to an ideal sequence. [Also see Research Article by Carlson et al.] Authors: Sarah B. Joseph, Ronald Swanstrom (Source: Science: Current Issue)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
[Perspective] Persistence by proliferation?
Latently HIV-infected cells driven to proliferate may raise a further challenge for eradication strategies. [Also see Research Article by Maldarelli et al.] Authors: David Margolis, Frederic Bushman (Source: Science: Current Issue)
[Editorial] End of AIDS?Hype versus hope
Since 2001, HIV incidence has declined by 33% worldwide, and more than 9.7 million people with HIV have gained access to treatment.* The Joint United Nations Programme on HIV/AIDS launched the Getting to Zero strategy (2011?2015) that includes zero new infections, zero deaths from HIV, and zero discrimination. Aspirational statements such as ?the end of AIDS? have also prevailed. However, do such pronouncements help or hurt? Do they motivate action, or do they risk incredulity, leading to inaction? Do such aspirations epitomize hype or hope? Authors: Wafaa M. El-Sadr, Katherine Harripersaud, Ronald Bayer (Source: Science: Current Issue)
[Special Issue News] Prevention, Papua New Guinea style
In the mountainous, remote Eastern Highlands of Papua New Guinea, people gather in makeshift cinema houses to watch videos that feature people from their communities who became infected by HIV. The stars of the videos come to viewings, too, speaking with the audience about their experiences, as well as about measures they can take to protect themselves and the effective antiretroviral treatment available if they do become infected. Made by students at the University of Goroka, the videos are in the local pidgin and attract people who are not often reached by mass media campaigns that attempt to educate the public about HIV/AIDS. (Source: Science: This Week)
[Special Issue News] Malaysia: Malaysia tries to follow Australia's path
Adeeba Kamarulzaman, a leading HIV/AIDS researcher who is the dean of the faculty of medicine at the University of Malaya, studied in Australia from the time she was in high school, and, when she returned home to Malaysia, successfully lobbied the government to import harm reduction strategies that had worked there. Although many Malaysians are afraid to confront their government, Kamarulzaman has repeatedly pushed for evidence-based reforms, regardless of the political sensitivities. As transmission has shifted primarily from drug users sharing equipment to sexual transmission, she is now advocating for prevention and treatment efforts that target some of the most highly stigmatized groups in the country, including men who have sex with men, transgenders, and sex workers. (Source: Scienc...
Perceptions of health care services and HIV-related health-seeking behavior among Uganda adolescents
(Source: AIDS Care)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Urban adolescent sexual and reproductive health in low-income and middle-income countries
One of the most important aspects of adolescent health is sexual and reproductive health (SRH). Currently, sexually transmitted infections (STIs) threaten the health of adolescents more than any other age group, and as many as 2.2 million adolescents are living with HIV. Understanding adolescents&rsquo; SRH needs and how to invest in improving their health can be best addressed by knowing more about the contexts that increase their vulnerability to poor sexual health outcomes. Recent evidence has highlighted an increasingly marginalised segment of the adolescent population&mdash;and that is the urban poor adolescent population in low and middle income countries (LMIC). Using an urban health framework, this paper examines the contextual factors within an urban community that influence the S...
Tuning transcription of nutrient utilization genes to catabolic rate promotes growth in a gut bacterium
We report that the regulator controlling utilization of chondroitin sulfate (CS) in the mammalian gut symbiont Bacteroides thetaiotaomicron is activated by an intermediate in CS breakdown rather than CS itself. We determine that the rate?determining enzyme in CS breakdown is responsible for degrading this intermediate, and establish that the levels of the enzyme increase 100 fold whereas those of the regulator remain constant upon exposure to CS. Because enzyme and regulator compete for the intermediate, B. thetaiotaomicron tunes transcription of CS utilization genes to CS catabolic rate. This tuning results in a transient increase in CS utilization transcripts upon exposure to excess CS. Constitutive expression of the rate?determining enzyme hindered activation of CS utilization genes...
Physicochemical property-driven optimization of diarylaniline compounds as potent HIV-1 non-nucleoside reverse transcriptase inhibitors.
Authors: Liu N, Qin B, Sun LQ, Yu F, Lu L, Jiang S, Lee KH, Xie L Abstract Using physicochemical property-driven optimization, twelve new diarylaniline compounds (DAANs) (7a-h, 11a-b and 12a-b) were designed and synthesized. Among them, compounds 12a-b not only showed high potency (EC50 0.96-4.92nM) against both wild-type and drug-resistant viral strains with the lowest fold change (FC 0.91 and 5.13), but also displayed acceptable drug-like properties based on aqueous solubility and lipophilicity (LE&gt;0.3, LLE&gt;5, LELP&lt;10). The correlations between potency and physicochemical properties of these DAAN analogues are also described. Compounds 12a-b merit further development as potent clinical trial candidates against AIDS. PMID: 25042339 [PubMed - as supplied by publisher] ...
Girl who was declared 'functionally cured' of HIV now has active virus
A girl who was seemingly cured of HIV following aggressive drug therapy just hours after her birth was recently discovered to be infected with the virus that causes AIDS after all, doctors announced Thursday. (Source: Los Angeles Times - Science)
Child Hoped to Be Cured of HIV Shows Signs of Virus
A Mississippi child born with the AIDS virus who scientists thought might have been cured following drug treatment has shown signs of infection again. (Source: WSJ.com: Health)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
HIV detected in ?cured? Mississippi Baby, Creating Huge AIDS Therapy Setback
The infant was placed back on medication but the clinical trial to replicate virus suppression is still expected to proceed -- Read more on ScientificAmerican.com (Source: Scientific American - Official RSS Feed)
Mississippi Girl Thought Cured of HIV Shows Signs of Infection
After more than two years of no drug therapy, she's back on medication; development disappoints doctors, researchers Source: HealthDay Related MedlinePlus Pages: HIV/AIDS Medicines, HIV/AIDS and Pregnancy (Source: MedlinePlus Health News)
'Mississippi Baby' Thought 'Cured' of HIV Relapses'Mississippi Baby' Thought 'Cured' of HIV Relapses
An infant who was seemingly cured of HIV now has detectable levels of the virus after 2 years without any evidence of the virus. Medscape Medical News (Source: Medscape Medical News Headlines)
OPINION: Unleashing African Young People?s Potential
Girls attend school in South Africa. Healthy, educated young people can help break the cycle of poverty. Credit: UNFPABy Adebayo FayoyinJOHANNESBURG, Jul 10 2014 (IPS) An African proverb says ?a child that we refuse to build today will end up selling the house that we may build tomorrow.? The moral of this is clear. Unless we invest in our children and young people today, they might become a threat or a burden in the future.As the international community commemorates World Population Day on July 11, Africa?s growing youth population should be recognised as a ?powerful force for change? that requires greater investment today. Judging by the current challenges confronting young people, the extent to which African countries are investing in the youth is unclear. More young people Ac...
Phylogenetic Analysis of Human Immunodeficiency Virus Type 2 Isolated from Cuban Individuals
AIDS Research and Human Retroviruses , Vol. 0, No. 0. (Source: AIDS Research and Human Retroviruses)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Helping Seniors with Low Vision Maintain Independence
Each day, approximately 10,000 Americans turn 65, and one in six adults this age and older has a vision impairment that cannot be corrected with glasses or contact lenses.[1] As part of its support for Senior Independence Month this July, the American Academy of Ophthalmology is providing older adults with low vision guidance on how to make the most of their remaining sight and keep their independence. (Source: Disabled World)
Caring for Persons with Early Childhood Trauma, PTSD, and HIV: a Curriculum for Clinicians.
Authors: Tavakkoli M, Cohen MA, Alfonso CA, Batista SM, Tiamson-Kassab ML, Meyer P Abstract Access and adherence to medical care enable persons with HIV to live longer and healthier lives. Adherence to care improves quality of life, prevents progression to AIDS, and also has significant public health implications. Early childhood trauma-induced posttraumatic stress disorder (PTSD) is one factor that has been identified as an obstacle to adherence to both risk reduction and HIV care. The authors developed a 4-h curriculum to provide clinicians with more confidence in their ability to elicit a trauma history, diagnose PTSD, and address trauma and its sequelae in persons with HIV to improve adherence to medical care, antiretroviral medications, and risk reduction. The curriculum was d...
Prevalence and Correlates of Cryptococcal Antigen Positivity Among AIDS Patients - United States, 1986-2012.
This report describes the results of that analysis, which indicated the overall prevalence of CrAg positivity in this population to be 2.9% (95% confidence interval [CI] = 2.2%-3.7%). PMID: 25006824 [PubMed - as supplied by publisher] (Source: MMWR Morb Mortal Wkl...)
HIV Resurfaces in "Mississippi Baby" Many Presumed Cured
The AIDS virus persists even when undetected by ultrasensitive tests for more than 2 years (Source: ScienceNOW)
Fast Voltammetry of Metals at Carbon-Fiber Microelectrodes: Copper Adsorption onto Activated Carbon aids Rapid Electrochemical Analysis
Analyst, 2014, Accepted ManuscriptDOI: 10.1039/C4AN00937A, PaperPavithra Pathirathna, Srimal Samaranayake, Christopher W. Atcherley, Kate L Parent, Michael L. Heien, Shawn P McElmurry, Parastoo HashemiRapid, in situ trace metal analysis is essential for understanding many biological and environmental processes. For example, trace metals are thought to act as chemical messengers in the brain. In...The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Analyst latest articles)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Tanzania: People Living With HIV/Aids Urged to Form Economic Groups
[Daily News]CONTRACTING HIV/AIDS is never condemnation to begging and living a worthless life, as some HIV-positive individuals have proved to be highly productive people, leading lives as any other person, Tanzania Commission for AIDS (TACAIDS) Chairperson, Dr Fatma Mrisho, said. (Source: AllAfrica News: Health and Medicine)
Tanzania: Aids Law Now Appears Redundant
[Daily News]IN 2005, a national report on the prevalence of HIV/AIDS showed that by the end of 2004 it was estimated that 1.3 million Tanzanians had fallen victim to the virus, with the infection rate standing at seven per cent among the sexually active age groups. (Source: AllAfrica News: HIV-Aids and STDs)
Kenya: Urgently Set Up HIV Fund
[The Star]Civil society groups want the government to set aside money so that there are no stock outs of ARV's and testing kits in public hospitals. They say more donors continue to pull out of funding, thus posing a serious challenge in the fight against HIV. (Source: AllAfrica News: HIV-Aids and STDs)
Special Issue: The fight against HIV/AIDS
Experts weigh in on the state of the global epidemic (Source: ScienceNOW)
Despite setback, 'Mississippi Baby' represents significant breakthrough in effort to end AIDS
(Elizabeth Glaser Pediatric AIDS Foundation) In response to today's announcement that the 'Mississippi Baby,' believed to have been functionally cured of HIV, has now been found to have detectable levels of the virus, the Elizabeth Glaser Pediatric AIDS Foundation expresses disappointment in this setback but remains hopeful that the scientific breakthrough that allowed the child's HIV levels to remain undetectable for more than two years will continue to help researchers understand how to control HIV and ultimately develop a cure. (Source: EurekAlert! - Medicine and Health)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Gender Role Behaviors of High Affiliation and Low Self-Silencing Predict Better Adherence to Antiretroviral Therapy in Women with HIV
AIDS Patient Care and STDs , Vol. 0, No. 0. (Source: AIDS Patient Care and STDs)
Molecular Epidemiology and Clinical Features of Human T Cell Lymphotropic Virus Type 1 Infection in Spain
AIDS Research and Human Retroviruses , Vol. 0, No. 0. (Source: AIDS Research and Human Retroviruses)
When do vertical programmes strengthen health systems? A comparative assessment of disease-specific interventions in India
Conclusions Disease-specific programmes in India are widely regarded as having made a substantial contribution in disease control. They can have both positive and negative effects on health systems. Certain conditions are necessary for them to have a positive influence on health systems&mdash;the programme needs to have an explicit policy to strengthen local health systems, and should also be embedded within the health system administration. (Source: Health Policy and Planning)
[Special Issue News] Australia: First, do harm reduction
Shortly after the AIDS epidemic surfaced in Australia, an aggressive effort began to prevent the spread of HIV in people who inject drugs. The harm reduction movement that evolved provided clean needles and syringes to users, as well as opiate substitutes like methadone that are not injected. A medically supervised injecting center also opened in Sydney?the first of its kind in the Southern Hemisphere?where people receive clean needles and syringes and legally use their drugs. HIV never got a serious foothold in this extremely vulnerable population, and Australia's harm reduction strategies eventually spread to nearby Indonesia and Malaysia, which initially had epidemics driven mainly by injecting drug use. (Source: Science: This Week)
Novel Agent Volasertib Doubles Responses in AMLNovel Agent Volasertib Doubles Responses in AML
Older patients with acute myeloid leukemia (AML) are not good candidates for intensive induction therapy, but an experimental agent might bolster the effectiveness of a standard treatment. Medscape Medical News (Source: Medscape Medical News Headlines)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
HIV/TB Access Intern
Reports to: HIV/AIDS Policy Advisor for the Access CampaignType of position: Intern, paidTime Commitment: 20 hrs/weekDuration: 3 monthsLocation: New York City Language English (Source: MSF News)
Namibia: Eenhana VTC Trainees Promise to Deliver
[New Era]Trainees of the Eenhana Vocational Training Centre (EVTC) are not only promising to successfully complete their training but to deliver in their trade when they go into practicing their trades. (Source: AllAfrica News: HIV-Aids and STDs)
Namibia: Eenhana VTC Trainee Values HIV, Aids Awareness Session
[New Era]Trainees at the Eenhana Vocational Training Centre (EVTC) here seem to appreciate the HIV and AIDS awareness presentation that the Namibia Planned Parenthood Association (NAPPA) held at the Centre. (Source: AllAfrica News: HIV-Aids and STDs)
Zambia: Angolans Seek HIV, TB Treatment in Chavuma
[Times of Zambia]AN INFLUX of Angolans has been recorded in Chavuma in North-Western Province seeking HIV/AIDS and Tuberculosis treatment among others, Chavuma District Commissioner Lawrence Kayumba has said. (Source: AllAfrica News: HIV-Aids and STDs)
Kenya: Why Reproductive Health Care Bill Would Help Manage Population
[The Star]The Reproductive Health Care Bill has elicited mixed reactions. While some have supported it saying it would help reduce the rate of HIV infections and deal with the rising cases of teenage pregnancies, others have castigated it on grounds that it would erode children's moral behavior. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Uganda: Uganda Making Strong Strides in HIV Response - Rugunda
[Observer]The increment of HIV prevalence rate from 6.4 per cent in 2004/5 to 7.3 per cent in 2011 must have woken Uganda out of her slumber. (Source: AllAfrica News: HIV-Aids and STDs)
Nigeria: Fayemi Writes Ekiti Assembly Over More Lgas
[Independent]Governor Kayode Fayemi of Ekiti State has written to Ekiti State House of Assembly over plans by his administration to create 18 additional council areas, to be called local council development areas (LCDAs). (Source: AllAfrica News: HIV-Aids and STDs)
Expectation of Volunteers Towards the Vaccine Efficacy of the Prime-Boost HIV Vaccine Phase III Trial During Unblinding
AIDS Research and Human Retroviruses , Vol. 0, No. 0. (Source: AIDS Research and Human Retroviruses)
Living with a symptomatic rotator cuff tear 'bad days, bad nights': a qualitative study
Conclusions: Clinicians need to appreciate and understand the intensity and shocking nature of pain that may be experienced by participants with known rotator cuff tears and understand the detrimental impact tears can have upon all areas of patient's lives. Clinicians also need to be aware of the potential emotional impact caused by cuff tears and to ensure that patients needing help for conditions such as depression are speedily identified and provided with support, explanation and appropriate treatment (Source: BMC Musculoskeletal Disorders)
Type I interferon responses in rhesus macaques prevent SIV infection and slow disease progression
Nature advance online publication 09 July 2014. doi:10.1038/nature13554 Authors: Netanya G. Sandler, Steven E. Bosinger, Jacob D. Estes, Richard T. R. Zhu, Gregory K. Tharp, Eli Boritz, Doron Levin, Sathi Wijeyesinghe, Krystelle Nganou Makamdop, Gregory Q. del Prete, Brenna J. Hill, J. Katherina Timmer, Emma Reiss, Ganit Yarden, Samuel Darko, Eduardo Contijoch, John Paul Todd, Guido Silvestri, Martha Nason, Robert B. Norgren, Brandon F. Keele, Srinivas Rao, Jerome A. Langer, Jeffrey D. Lifson, Gideon Schreiber & Daniel C. Douek Inflammation in HIV infection is predictive of non-AIDS morbidity and death, higher set point plasma virus load and virus acquisition; thus, therapeutic agents are in development to reduce its causes and consequences. However, inflammation may simultaneously co...<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Two-port laparoscopic management of a giant pseudocyst complicating ventriculoperitoneal shunt
Sandesh V Parelkar, Beejal V Sanghvi, Devdas S Samala, Bhupesh A Paradkar, Shalil H Patil, Sanjay N OakJournal of Indian Association of Pediatric Surgeons 2014 19(3):181-183Insertion of a ventriculo-peritoneal (VP) shunt is the most common operative procedure for the treatment of hydrocephalus in children. Of the several causes of shunt malfunction, cerebrospinal fluid (CSF) pseudocyst is relatively uncommon. There are several modalities to treat a CSF pseudocyst. Laparotomy is required, at times, more than once. We managed a patient of CSF pseudocyst with two-port laparoscopy, by deroofing the psuedocyst and repositioning of the shunt. This minimally invasive technique avoids morbidity associated with laparotomy and aids in early recovery. (Source: Journal of Indian Association of Pediatr...
The AIDS Pandemic in Historic Perspective
Potent antiretroviral drugs (ART) have changed the nature of AIDS, a once deadly disease, into a manageable illness and offer the promise of reducing the spread of HIV. But the pandemic continues to expand and cause significant morbidity and devastation to families and nations as ART cannot be distributed worldwide to all who need the drugs to treat their infections, prevent HIV transmission, or serve as prophylaxis. Furthermore, conventional behavioral prevention efforts based on theories that individuals can be taught to modify risky behaviors if they have the knowledge to do so have been ineffective. Noting behavioral strategies targeting individuals fail to address broader social and political structures that create environments vulnerable to HIV spread, social scientists and public he...
Validation of a Histoplasma ELISA antigenuria test in Colombian patients with AIDS for diagnosis and follow-up during therapy.
Authors: Caceres DH, Scheel CM, Tobón AM, Ahlquist Cleveland A, Restrepo A, Brandt ME, Chiller T, Gómez BL Abstract We validated an antigen capture ELISA test in Colombian persons with AIDS and proven histoplasmosis, and evaluated the correlation between antigenuria and clinical improvement during follow up. The sensitivity of the H. capsulatum ELISA was 86% and the overall specificity was 94%. The antigen test successfully monitored response to therapy. PMID: 25008902 [PubMed - as supplied by publisher] (Source: Clinical and Vaccine Immunology)
Interactions between HIV-1 and the Cell-Autonomous Innate Immune System.
Authors: Towers GJ, Noursadeghi M Abstract HIV-1 was recognized as the cause of AIDS in humans in 1984. Despite 30 years of intensive research, we are still unraveling the molecular details of the host-pathogen interactions that enable this virus to escape immune clearance and cause immunodeficiency. Here we explore a series of recent studies that consider how HIV-1 interacts with the cell-autonomous innate immune system as it navigates its way in and out of host cells. We discuss how these studies improve our knowledge of HIV-1 and host biology as well as increase our understanding of transmission, persistence, and immunodeficiency and the potential for therapeutic or prophylactic interventions. PMID: 25011104 [PubMed - as supplied by publisher] (Source: Cell Host and Microbe)
Type I interferon responses in rhesus macaques prevent SIV infection and slow disease progression
Authors: Netanya G. Sandler, Steven E. Bosinger, Jacob D. Estes, Richard T. R. Zhu, Gregory K. Tharp, Eli Boritz, Doron Levin, Sathi Wijeyesinghe, Krystelle Nganou Makamdop, Gregory Q. del Prete, Brenna J. Hill, J. Katherina Timmer, Emma Reiss, Ganit Yarden, Samuel Darko, Eduardo Contijoch, John Paul Todd, Guido Silvestri, Martha Nason, Robert B. Norgren Jr, Brandon F. Keele, Srinivas Rao, Jerome A. Langer, Jeffrey D. Lifson, Gideon Schreiber & Daniel C. Douek Inflammation in HIV infection is predictive of non-AIDS morbidity and death, higher set point plasma virus load and virus acquisition; thus, therapeutic agents are in development to reduce its causes and consequences. However, inflammation may simultaneously confer both detrimental and beneficial effects. This dichotomy is p...<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Burden of Nonnucleoside Reverse Transcriptase Inhibitor Resistance in HIV-1-Infected Patients: A Systematic Review and Meta-Analysis
AIDS Research and Human Retroviruses , Vol. 0, No. 0. (Source: AIDS Research and Human Retroviruses)
The Effects of Chronic Binge Alcohol on the Genital Microenvironment of Simian Immunodeficiency Virus-Infected Female Rhesus Macaques
AIDS Research and Human Retroviruses , Vol. 0, No. 0. (Source: AIDS Research and Human Retroviruses)
Zambia: 'Let's Fight Early Marriages'
[Times of Zambia]AN INTERNATIONAL non-governmental organisation (NGO) working to lessen the devastating psychosocial impact of poverty, conflict, HIV/AIDS among children and youths has called for concerted efforts in addressing the challenges fueling early marriages and child sexual abuse in Zambia. (Source: AllAfrica News: HIV-Aids and STDs)
Liberia: Liberians Lead Immigrant With Highest HIV Diagnoses in Minnesota
[FrontPageAfrica]Minnesota -Some 301 people were newly infected with HIV in Minnesota in 2013, a 4 percent drop compared to 314 a year earlier, but a worrying trend persists among the Liberian immigrant community, according to a recent report released by Minnesota Department of Health (MDH). (Source: AllAfrica News: HIV-Aids and STDs)
Birth in bigger hospitals aids survival for pre-term babies
Premature babies born in bigger hospitals are more likely to survive than those born in smaller ones, a new UK study suggests. (Source: Nursing Times Breaking News)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Kenya: Go for ARVs, Infected Couples Told
[The Star]COUPLES living with HIV should go for Anti Retro Viral drugs, a clergyman has said. Tukiko Jakech, a pastor at Ogeng'o Seventh Day Adventist Church, said HIV-Aids is a reality that needs proper medical attention. (Source: AllAfrica News: HIV-Aids and STDs)
Kenya: The Week - Health & Fitness
[The Star]HIV rises among couples and cohabiting partners (Source: AllAfrica News: HIV-Aids and STDs)
Kenya: Why HIV Does Not Kill Anymore
[The Star]When it comes to HIV, it is not the virus that kills you, it is everything else. Your body's immunity is weakened and a simple curable disease is what often gets you. (Source: AllAfrica News: HIV-Aids and STDs)
Decisional Capacity Among Youth with HIV: Results from the MacArthur Competence Tool for Treatment
AIDS Patient Care and STDs , Vol. 0, No. 0. (Source: AIDS Patient Care and STDs)
The prevalence of transmitted HIV drug resistance among MSM in Anhui province, China
Conclusions: In Anhui, CRF01_AE strains contributed to most of the HIV infections among MSM, and the prevalence of TDR was relatively low in this population. Further studies should be performed to evaluate the trend of TDR among MSM in Anhui and to inform first-line antiretroviral treatment. (Source: AIDS Research and Therapy)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Counting Down: HIV Prison-Based Peer Education Programs and Their Connection to Reduced Disciplinary Infractions
This study analyzed rates of disciplinary infractions among 49 female prisoners that worked in two HIV prison-based peer programs (AIDS, Counseling, and Education [ACE] and CARE [Counseling, AIDS, Resource, and Education]) as peer educators during their incarceration. These women were unlikely to jeopardize their position by engaging in unlawful or deviant behaviors. Results showed that working in programs like ACE/CARE prevented periods of maladjustment and subsequent disciplinary infractions during incarceration. (Source: International Journal of Offender Therapy and Comparative Criminology)
Comparing the effect of a decision aid plus patient navigation with usual care on colorectal cancer screening completion in vulnerable populations: study protocol for a randomized controlled trial
This study will test a combined decision aid and patient navigator intervention on screening completion in diverse populations of vulnerable primary care patients. Methods: We will conduct a multisite, randomized controlled trial with patient-level randomization. Planned enrollment is 300 patients aged 50 to 75 years at average CRC risk presenting for appointments at two primary clinics in North Carolina and New Mexico. Intervention participants will view a video decision aid immediately before the clinic visit. The 14 to 16 minute video presents information about fecal occult blood tests and colonoscopy and will be viewed on a portable computer tablet in English or Spanish. Clinic-based patient navigators are bilingual and bicultural and will provide both face-to-face and telephone-based ...
Adult hearing loss services: Monitor launches review into choices available for patients
Around 500,000 patients over the age of 55 use these services every year. They may be able to choose between alternative providers of hearing tests, hearing aids and aftercare. This is because their local commissioners have taken out contracts with multiple providers, including some independent sector organisations as well as NHS bodies. These arrangements cover half of England and cost the NHS about £200 million a year. As a result of concerns about some adult hearing services, Monitor is now working with Action on Hearing Loss and other relevant charities to understand whether the interests of patients are well served. More ..... (Source: NHS Networks)
Decision Aids Help Patients but Still Are Not Widely Used
(Source: JNCI)
From rhetoric to reality? Putting HIV and AIDS rights talk into practice in a South African rural community.
We present a case study of the Entabeni Project in South Africa - in which a foreign-funded NGO sought to work with female health volunteers in a deep rural community to increase their access to two HIV-relevant rights: women's rights (especially gender equality) and rights to health (especially access to HIV- and AIDS-related services). Whilst the project had short-term health-related successes, it was less successful in implementing a gender empowerment agenda. The concept of women's rights had no purchase with women who had little interest in directly challenging male power, foregrounding the fight against poverty as their main preoccupation. The area's traditional chief and gatekeeper insisted the project should remain 'apolitical'. Project funders prioritised 'numbers reached' over a ...<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Racial/ethnic disparities in HIV medical studies examined by researchers
Social/behavioral intervention vastly increased the number of African American and Latino individuals living with HIV/AIDS who enrolled in HIV/AIDS medical studies, a study has found. Nine out of 10 participants who were found eligible for studies decided to enroll, compared to zero participants among a control group. (Source: ScienceDaily Headlines)
Zimbabwe: Lessons for Climate Sector From HIV/Aids
[The Herald]Climate change experts will meet in Kariba on July 15 for a final review of Zimbabwe's climate change strategy before possible endorsement and adoption, as the country seeks to deliver greater efficiency in climate response.Two years since the process of compiling the National Climate Change Response Strategy (NCCRS) began; the crucial document may now be eventually released at a later date this year, hoping to straighten the existing budgetary and planning discord on adaptive and mitigatory action. (Source: AllAfrica News: Health and Medicine)
Adverse Events According to CD4 Count at the Start of ARTAdverse Events According to CD4 Count at the Start of ART
Are HIV patients who start ART with a higher CD4 count at greater risk of ART-related adverse events? AIDS (Source: Medscape Today Headlines)
Nigeria: Nigeria Is Largest Recipient of U.S Aid On HIV and Aids Prevention - Entwistle
[Vanguard]Nigeria is the largest recipient of the U.S President's Emergency Plan for Aids Relief (PEPFAR) in the world, U.S Ambassador to Nigeria, Mr James Entwistle, has said. (Source: AllAfrica News: HIV-Aids and STDs)
Southern Africa: Arasa and Partners to Host Workshop On HIV-Aids Reporting
[MISA]The AIDS and Rights Alliance for Southern Africa (ARASA) is a partnership of 73 non-governmental organisations (NGOs) working together to promote a rights-based response to HIV and TB in southern and eastern Africa through capacity strengthening and advocacy. It is the only regional organisation that is structured in the form of a partnership of country-based civil society organisations working together to promote human rights and health in the context of HIV, tuberculosis (TB) and sexual and reproductive (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Nigeria: U.S. Boosts HIV/Aids Treatment With U.S.$458 Million Aid
[Independent]Abuja -The United States (US) has reiterated its support to Nigeria in the face of wanton killings by the Boko Haram insurgency, saying, "we want Nigeria to win the war against terrorism." (Source: AllAfrica News: HIV-Aids and STDs)
Tanzania: Let Us Do Away With Outdated Traditions
[Daily News]Last week there was shocking news from Kajiado, a town located not very far from the Kenya's capital, Nairobi. (Source: AllAfrica News: HIV-Aids and STDs)
Nigeria: Nigeria, Largest Recipient of U.S. Aid On HIV Prevention - Entwistle
[Premium Times]Mr. Entwistle made this known at a reception to celebrate the 238th anniversary of U.S. Independence in Abuja on Friday night. (Source: AllAfrica News: HIV-Aids and STDs)
NYU researchers tackle racial/ethnic disparities in HIV medical studies
(New York University) Study finds social/behavioral intervention vastly increased the number of African American and Latino individuals living with HIV/AIDS who enrolled in HIV/AIDS medical studies. Nine out of 10 participants who were found eligible for studies decided to enroll, compared to zero participants among a control group. (Source: EurekAlert! - Social and Behavioral Science)
Virologic outcomes of second-line antiretroviral therapy in Eastern European country of Georgia
Conclusions: The study demonstrated favourable virological outcomes of the second-line ART in Georgia. Majority of patients, including IDUs, achieved sustained virological response over 36 month period. The findings highlight the need of improving adherence. (Source: AIDS Research and Therapy)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Antiretroviral penetration into the CNS and incidence of AIDS-defining neurologic conditions
Conclusions: We estimated that initiation of a combined antiretroviral therapy regimen with a high CPE score increases the risk of HIV dementia, but not of other neuroAIDS conditions. (Source: Neurology)
DEFB1 5'UTR Polymorphisms Modulate the Risk of HIV-1 Infection in Mexican Women.
Authors: Estrada-Aguirre JA, Osuna-Ramirez I, de Prado-Montes EO, Ochoa-Ramirez LA, Ramirez M, Magallon-Zazueta LG, Gonzalez-Beltran MS, Cazarez-Salazar SG, Rangel-Villalobos H, Velarde-Felix JS Abstract Immunologic and genetic factors are involved in HIV-1/AIDS pathogenesis. Defensins are key molecules in innate immunity that participate in the control and/or development of infection and disease. Using PCR-RFLPs, we determined the association between HIV-1/AIDS and human ?-defensin 1 (DEFB1) 5'UTR -52 G/A (rs1799946), -44 C/G (rs1800972), and -20 G/A (rs11362) polymorphisms in three groups of women from the state of Sinaloa, located in the Northwest region of Mexico: i) sex-workers; ii) healthy blood donors; and iii) HIV-1 patients. The -52GG genotype was more frequent in blood d...
Elevated postinjury thrombospondin 1-CD47 triggering aids differentiation of patients' defective inflammatory CD1a+dendritic cells.
Authors: Bandyopadhyay G, Bandyopadhyay S, Bankey PE, Miller-Graziano CL Abstract A subset of Pts develops dysfunctional MO to inflammatory DC differentiation and immunosuppression. MDDC, a newly described DC subset, is pivotal in initiating antibacterial responses. Endogenous proteins are known to alter MO to MDDC differentiation. In particular, trauma-elevated TSP-1, a protein that is known to affect MO functions, could trigger MDDC differentiation defects. We hypothesized that TSP-1-deranged differentiation of inflammatory CD1a(+)MDDC would negatively alter activation of immune functions, thereby increasing the risk of postinjury infections. Post-trauma increased TSP-1 levels in patients' plasma and MO correlated with two distinct MDDC differentiation dysfunctions: the previousl...
Viral pathogenesis: Macaque model for AIDS
This study now shows that HIV-1 adapts to replicate efficiently and cause AIDS in pig-tailed macaques. The animals were inoculated with HIV-1 and treated (Source: Nature Reviews Microbiology)
The Uncertain Future of Male Masturbation
In the not too distant past, male masturbatory aids were limited, but technological advancements are dramatically changing the masturbation experience. However, we don't know if these will prove ultimately harmful to romantic relationships.read more (Source: Psychology Today Sex Center)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Malawi: Unsafe Sex Irks HIV/Aids Fighters
[Malawi News Agency]Lilongwe -The Principal Secretary in the Department of Nutrition and HIV/Aids in the Office of the President and Cabinet, Edith Mkawa has faulted the mechanisms utilized to dispatch messages of HIV/Aids in early 1990s saying it contributed to the increased transmission of the virus. (Source: AllAfrica News: Health and Medicine)
Measuring HIV/AIDS-Related Stigma Across South Africa: A Versatile and Multidimensional Scale
Reducing HIV/AIDS-related stigma is critical in the fight against HIV/AIDS. Although national campaigns and prevention programs have been implemented across South Africa to address this critical concern, assessing the impact of these initiatives is difficult as it requires that measurement of HIV/AIDS-related stigma is uniform and comparable nationwide. The appropriateness of existing stigma measures for this task is unclear as measurement of HIV/AIDS-related stigma may be qualitatively different across South Africa&rsquo;s diverse population. The current study assesses a theoretically and culturally informed multidimensional, HIV/AIDS-related stigma scale for measurement invariance across a sample drawn from two culturally distinct South African provinces: Limpopo (n = 597) and Western Ca...
Comprehensive Characterization of Commercially Available Canine Training Aids
(Source: Forensic Science International)
Representations of vulnerability and empowerment of nurses in the context of HIV/AIDS
The aim of this study was to analyze the social representations of vulnerability and empowerment of nurses, in the context of their relationships with the work environment, in which they care for people with HIV/AIDS. A qualitative and descriptive study was carried out with 30 nurses in a public hospital that is a reference for HIV/AIDS care. The theoretical framework of the procedural approach from the Social Representations Theory was adopted. The interviews were transcribed and submitted to thematic content analysis using the software Nvivo 9.0. Vulnerability was expressed as embarrassment, dissatisfaction, distress, frustration, insecurity, overload and stress. In turn, empowerment was expressed in the form of positive interpersonal relationships, moral and operational support from the...
Zambia: Zambia Focuses On Young People for a More Prosperous and Aids-Free Generation
[Key Correspondents]As people with HIV in Zambia are now living longer and healthier lives, the focus is shifting to young people and the opportunity to work towards an AIDS-free generation. (Source: AllAfrica News: Health and Medicine)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Nigeria: Lagos HIV Agency Joins Regional Fight Against Scourge
[CAJ News]Lagos -THE Lagos State AIDS Control Agency (LSACA) is partnering with other West African countries to reduce HIV/AIDS prevalence in the region. (Source: AllAfrica News: HIV-Aids and STDs)
Liberia: GOL, Partners Discuss HIV Strategic Plan
[Heritage]The Government of Liberia (GoL) through the National AIDS Commission (NAC) and the National AIDS/STIs Control Program (NACP) in collaboration with the United Nations System and civil society organizations in Liberia have commenced a three day technical review and validation retreat of the newly developed National Strategy Plan (NSP) 2015-2020 in Carreysburg City-Montserrado County. (Source: AllAfrica News: HIV-Aids and STDs)
Namibia: Condom Users Face Stigmatisation
[New Era]Windhoek -Although condom usage is believed to have increased in Namibia compared to previous years, there is still a stigma attached to people who buy condoms from shops or pubs, who are generally seen as promiscous. (Source: AllAfrica News: HIV-Aids and STDs)
Micronucleated erythrocytes in newborn rats exposed to raltegravir placental transfer.
The objective of this study is to evaluate the transplacental genotoxic effect of raltegravir in newborn rats. We evaluated the number of micronucleated erythrocytes (MNE), micronucleated polychromatic erythrocytes (MNPCE), and polychromatic erythrocytes (PCE) in the peripheral blood samples of the offspring of Wistar rats treated 6 days before birth with oral administration of raltegravir. The animals were randomly assigned to five groups as follows: raltegravir at doses of 15, 30, or 60?mg/day, cyclophosphamide 10?mg/kg (positive control), or 0.5?ml of sterile water (negative control). In addition, the effect of these drugs on the weight and height of newborns was assessed. There were no differences in the number of MNE, MNPCE, and PCE, and a slight decrease in the weight and heigh...
Discovery and full genome characterization of a new SIV lineage infecting red-tailed guenons (Cercopithecus ascanius schmidti) in Kibale National Park, Uganda
Conclusions: Our results show that the genetic diversity of SIVs infecting red-tailed guenons is greater than previously appreciated. This diversity could be the result of cross-species transmission between different guenon species or limited gene flow due to geographic separation among guenon populations. (Source: Retrovirology)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
HIV Infection and Risk, Prevention, and Testing Behaviors Among Injecting Drug Users - National HIV Behavioral Surveillance System, 20 U.S. Cities, 2009.
This report summarizes two separate analyses using unweighted data from 10,200 eligible IDUs in 20 MSAs from the second collection cycle of NHBS in 2009. Both an HIV infection analysis and a behavioral analysis were conducted. Different denominators were used in each analysis because of the order and type of exclusion criteria applied. For the HIV infection analysis, of the 10,200 eligible participants, 10,090 had a valid HIV test result, of whom 906 (9%) tested positive for HIV (range: 2%-19% by MSA). When 509 participants who reported receiving a previous positive HIV test result were excluded from this analysis, 4% (397 of 9,581 participants) tested HIV-positive. For the behavioral analysis, because knowledge of HIV status might influence risk behaviors, 548 participants who reported a ...
HIV Infection and Risk, Prevention, and Testing Behaviors Among Injecting Drug Users ? National HIV Behavioral Surveillance System, 20 U.S. Cities, 2009
This report summarizes data from the second collection cycle of NHBS in 2009. (Source: CDC HIV/AIDS Prevention)
MMWR: HIV Infection and Risk, Prevention, and Testing Behaviors Among Injecting Drug Users ? National HIV Behavioral Surveillance System, 20 U.S. Cities, 2009
This report summarizes data from the second collection cycle of NHBS in 2009. (Source: CDC HIV/AIDS Prevention)
MMWR: Drowsy Driving and Risk Behaviors ? 10 States and Puerto Rico, 2011?2012
This report summarizes the results of that analysis. (Source: CDC HIV/AIDS Prevention)
HOT TOPICS 2014: AIDS Revisited
(MedPage Today) -- Early this year, MedPage Today asked top experts in HIV/AIDS for their ideas of what would happen in 2014. How have their predictions panned out so far? (Source: MedPage Today Infectious Disease)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Nicotine replacement product to go on general sale
Move likely to drive down cost of anti-smoking aids (Source: The Irish Times - Health)
Some Docs, Nurses Fear Fallout From Hobby Lobby RulingSome Docs, Nurses Fear Fallout From Hobby Lobby Ruling
Several professional societies said the Supreme Court ruling may lead to employers stripping other services besides contraceptives from insurance coverage because of their religious beliefs. Medscape Medical News (Source: Medscape Hiv-Aids Headlines)
Malawi: Manet+ Bemoans the Scarcity of ARVs in Phalombe
[Malawi News Agency]Lilongwe -The Malawi Network of people living with HIV/AIDS (MANET+) on Wednesday bemoaned the scarcity of AntiRetroViral (ARV) drugs in some health centres of Phalombe, saying this is putting lives of many people living with the HIV virus at risk. (Source: AllAfrica News: HIV-Aids and STDs)
Malawi: New HIV Prevention Strategic Plan Aims At Zero Infections
[Malawi News Agency]Lilongwe -The re-invigorating HIV prevention symposium which took place in Lilongwe has high lightened the need to accommodate the discriminated sex workers and men having sex with fellow men in order to reduce prevalence rate in the country. (Source: AllAfrica News: HIV-Aids and STDs)
Kenya: HIV-Aids Tests for Nanyuki
[The Star]About 7,000 residents living with people with HIV-Aids will be tested in the next three months. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
South Africa: Inheriting HIV - a Bitter Pill to Swallow
[Health-e]Ten years after South Africa began providing free HIV treatment, a generation of children born with HIV continues to come of age with the virus. One young Mpumalanga man shares his story. (Source: AllAfrica News: HIV-Aids and STDs)
Zambia: Swedish Envoy's Support to Aids Fight in Prison Welcome
[Times of Zambia]THE call by Swedish Ambassador to Zambia Lena Nordstrom on all stakeholders to reach out to the prison population as part of the efforts to lower incidences of HIV/AIDS in Zambia should be taken seriously in the country's efforts to fight the pandemic. (Source: AllAfrica News: HIV-Aids and STDs)
Updated Recommendations for Laboratory Testing for the Diagnosis of HIV Infection
CDC and the Association of Public Health Laboratories (APHL) recently issued Updated Recommendations for Laboratory Testing for the Diagnosis of HIV Infection. This document also offers approaches for reporting test results to people ordering HIV tests and to public health authorities. The recommended algorithm is a sequence of tests used in combination to improve the accuracy of the laboratory diagnosis of HIV based on testing of serum or plasma specimens. More information is available: CDC: Quick Reference Guide - Laboratory Testing for the Diagnosis of HIV Infection: Updated Recommendations&nbsp; CDC: Suggested Reporting Language for the HIV Laboratory Diagnostic Testing Algorithm (Source: AIDSinfo At-a-Glance: Offering Information on HIV/AIDS Treatment, Prevention, and Research, ...
AIDSinfo Offers an Easy Way to Find HIV/AIDS-Related Clinical Trials
The AIDSinfo and infoSIDA clinical trial search tools make it easy to find HIV/AIDS-related clinical trials. Whether you are searching for trials accepting volunteers, looking for trials in a specific area of interest, or checking for clinical trial results, the search tool makes the job easy. Use the &quot;Search by Category&quot; menu to browse more than 180 preconfigured searches on a variety of topics. Categories include opportunistic infections, side effects, HIV-related drugs, prevention research, and much more.&nbsp;Once you select your search, you can click the &quot;Refine Search&quot; button on the results page to further tailor your search by attributes such as keyword, recruitment status, study site location, gender, and age. Our Advanced Search feature allows you to customiz...
Clinical, immunological, and virological outcomes of pediatric antiretroviral therapy in central China
Conclusions: Despite the limited small sample size, ART is an effective strategy for inhibiting HIV replication and reconstructing the immunological response in children with AIDS. (Source: BioMed Central)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Quality of life in individuals living with HIV/AIDS attending a public sector antiretroviral service in Cape Town, South Africa
We examined and compared the HRQoL in relation to ART status among HIV-infected patients in a public sector service in Cape Town, South Africa. In addition, we aimed to examine the relationship between ART status and HRQoL according to CD4 count strata. Methods: A cross sectional study sample of 903 HIV-infected patients who were categorized as not receiving ART (ART-naive) or receiving first-line ART for > 6 months (ART). HRQoL outcomes were compared in the two groups. HRQoL was assessed using the EQ-5D (five domains) and Visual Analogue Scale (EQ-5D VAS). Results: Of the total sample, 435 were categorised as ART naive (76% women) and 468 were on ART (78% women). There were no significant associations between groups for most of the EQ-5D domains, however ART-naive experienced a significan...
HIV and syphilis prevalence trends among men who have sex with men in Guangxi, China: yearly cross-sectional surveys, 2008-2012
Conclusions: HIV and the syphilis prevalence expansion among MSM suggest an urgent public health prevention challenge for Guangxi provincial health officials. Risk factors for each infection differed such that all MSM, each of whom might be at risk of HIV, syphilis or both, should be targets for heavy intervention. (Source: BMC Infectious Diseases)
VP1: Thoughts on Week 1 in Kikatiti Village
Written by volunteers Yoshi, Lisa, Kate, Even, Hellen and Hamida Last Thursday, June 19th, we had scheduled a meeting with a support group for people in Kikatiti who are living with HIV. During the day before the meeting, we started discussing how to approach the meeting. This was unlike the average teaching, one which includes the definition of HIV, its effects on the body after contraction, and how to protect oneself and the community from the disease. Their experience has clearly taught them more than anything we were supposed to tell them. We thus decided to treat it as a learning experience for ourselves about the state of HIV in Kikatiti. With regards to our conception of the problem of public health in the village and the areas of focus in our teachings, we found that the meeting wa...
VP1 Orientation and Village Move-in
The volunteer turned back, looking toward us through the rows of overgrown sunflowers and maize, as if to simultaneously assure us that she would be okay and also beg us to not leave her alone just yet. We piled back into the SIC truck, sides painted blue and red with a scene of the Boston Red Sox 2004 World Series championship, a last reminder of American life as the volunteers embark on their six weeks of village life in rural Tanzania. As we drive off, waving a temporary goodbye to the volunteer and accompanying Tanzanian teaching partner, as well as the hordes of young children who had gathered to welcome us, we breath of sigh of both relief and confidence, knowing that all 9 volunteers (3 from Harvard, 3 from the University of Arizona, 2 from UC Berkeley, and 1 from Harvey Mudd) and t...
?Haraka, Haraka Haina Baraka? ? ?Quickly, Quickly Brings No Blessings?- VP1
When I last sat cross-legged, clutching my battered notebook and half lost in the swirling dust kicked up along the sidelines of a Tanzanian soccer field, I knew two distinct truths: If the opportunity to return with SIC were presented, I would not hesitate in accepting? that, and the work which VP1 had started during the summer of 2013 was unfinished. Looking up, I remember seeing the shapes of my fellow volunteers moving among the crowd and between the tents which SIC had erected, leading rural farmers, soccer players and village elders by the hand to receive free HIV/AIDS tests. ?This is how change is brought about? I remember thinking to myself; each volunteer flying halfway around the world from institutions of higher learning, in order to engage and teach among the underserve...<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Aspirations and sex: Coming of age in the eye of the HIV storm
How do you shape your hopes, ambitions and expectations when growing up in an environment devastated by HIV/AIDS? One researcher found that young people between 16 and 25 in rural Kenya take a pragmatic approach to sexual risks because sexuality plays an important role in their quest for a better future. Anthropologists have an important role to play in prevention projects that take expectations of youngsters better into account. (Source: ScienceDaily Headlines)
Uganda: Musicians 'Reach a Hand Out' to Fight Aids
[Observer]When I first watched the video your ways on a local television station, the first thing that came to mind was how did all these artistes come together to record a song about getting the youth to change their ways to avoid the deadly scourge-HIV. The song features, Jamaican singer Nyan'da, who rocked Kampala recently, GNL Zamba, Big Trill, Irene Ntale, Maurice Hassa and Ray Signature. The vocals from each artiste were perfectly blended with each artiste being tasked to pen their verse. All the recording was (Source: AllAfrica News: HIV-Aids and STDs)
Risk Reduction Among HIV-Seroconcordant and -Discordant Couples: The Zambia NOW2 Intervention
AIDS Patient Care and STDs , Vol. 0, No. 0. (Source: AIDS Patient Care and STDs)
The effects of opioids on HIV reactivation in latently-infected T-lymphoblasts
Conclusions: Opioids reactivate HIV in vitro but at concentrations that are far above the plasma levels of analgesic regimes or drug concentrations found in IDUs. HIV reactivation was mediated by effects unrelated to opioid-receptor activation and was tightly linked to the cytotoxic activity of the substances at millimolar concentrations, suggesting that opioid-mediated reactivation of HIV was due to accompanying effects of cellular necrosis such as activation of reactive oxygen species and NF-kappaB. (Source: AIDS Research and Therapy)
PIQMIe: a web server for semi-quantitative proteomics data management and analysis
We present the Proteomics Identifications and Quantitations Data Management and Integration Service or PIQMIe that aids in reliable and scalable data management, analysis and visualization of semi-quantitative mass spectrometry based proteomics experiments. PIQMIe readily integrates peptide and (non-redundant) protein identifications and quantitations from multiple experiments with additional biological information on the protein entries, and makes the linked data available in the form of a light-weight relational database, which enables dedicated data analyses (e.g. in R) and user-driven queries. Using the web interface, users are presented with a concise summary of their proteomics experiments in numerical and graphical forms, as well as with a searchable protein grid and interactive vis...<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Enhancement of Tumor-Specific T Cell-Mediated Immunity in Dendritic Cell-Based Vaccines by Mycobacterium tuberculosis Heat Shock Protein X.
In conclusion, the high therapeutic response rates with tumor-targeted Th1-type T cell immunity as a result of HspX-stimulated DCs in two models suggest that HspX harnesses the exquisite immunological power and specificity of DCs for the treatment of tumors. PMID: 24990079 [PubMed - as supplied by publisher] (Source: Journal of Immunology)
Noninfectious Pulmonary Complications of Human Immunodeficiency Virus Infection.
Authors: Staitieh B, Guidot DM Abstract : Human immunodeficiency virus type 1 (HIV-1) is the retrovirus responsible for the development of AIDS. Its profound impact on the immune system leaves the host vulnerable to a wide range of opportunistic infections not seen in individuals with a competent immune system. Pulmonary infections dominated the presentations in the early years of the epidemic, and infectious and noninfectious lung diseases remain the leading causes of morbidity and mortality in persons living with HIV despite the development of effective antiretroviral therapy. In addition to the long known immunosuppression and infection risks, it is becoming increasingly recognized that HIV promotes the risk of noninfectious pulmonary diseases through a number of different mecha...
Gluten-free diet aids cognitive as well as physical wellbeing in coeliac disease.
Authors: Abstract People with coeliac disease often experience 'brain fog' in addition to intestinal problems, but a study suggests adhering to a gluten-free diet can lead to improvements in cognition as well as intestinal healing. PMID: 24985274 [PubMed - in process] (Source: Nursing Standard)
Perceptions of Speech-Language Pathologists Linked to Evidence-Based Practice Use in Skilled Nursing Facilities.
Conclusions: Part of evidence-based practice implementation may be influenced by clinician perceptions. Efforts to increase implementation of external memory aids in SNFs should address these clinician perceptions. PMID: 24989317 [PubMed - as supplied by publisher] (Source: American Journal of Speech-Language Pathology)
Short Communication: Genital Tumor Growth Factor-?1 Levels in HIV-Infected Indian Women Are Associated with Reduced Levels of Innate Antimicrobial Products and Increased HIV Shedding
AIDS Research and Human Retroviruses Jul 2014, Vol. 30, No. 7: 648-653. (Source: AIDS Research and Human Retroviruses)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
The Viral Make-Up Makes a World of Difference
AIDS Research and Human Retroviruses Jul 2014, Vol. 30, No. 7: 642-643. (Source: AIDS Research and Human Retroviruses)
Short Communication: Spectrum of Non-Hodgkin Lymphoma in an Urban Ryan White-Funded Clinic in the Established Antiretroviral Era
AIDS Research and Human Retroviruses Jul 2014, Vol. 30, No. 7: 665-669. (Source: AIDS Research and Human Retroviruses)
Short Communication: Circulating Plasma HIV-1 Viral Protein R in Dual HIV-1/Tuberculosis Infection
AIDS Research and Human Retroviruses Jul 2014, Vol. 30, No. 7: 644-647. (Source: AIDS Research and Human Retroviruses)
Risk Factors for Fatty Liver in AIDS Cohort StudyRisk Factors for Fatty Liver in AIDS Cohort Study
Are HIV positive men at a greater risk for developing fatty liver disease than men who are negative? This new study explains. The American Journal of Gastroenterology (Source: Medscape Today Headlines)
HIV Stigma Among Substance Abusing People Living with HIV/AIDS: Implications for HIV Treatment
AIDS Patient Care and STDs , Vol. 0, No. 0. (Source: AIDS Patient Care and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Pain Treatment and Antiretroviral Medication Adherence Among Vulnerable HIV-Positive Patients
AIDS Patient Care and STDs , Vol. 0, No. 0. (Source: AIDS Patient Care and STDs)
Cost-Effectiveness of Antiretroviral Therapy Expansion Strategies in Vietnam
AIDS Patient Care and STDs Jul 2014, Vol. 28, No. 7: 365-371. (Source: AIDS Patient Care and STDs)
HIV/AIDS and STD Updates
AIDS Patient Care and STDs Jul 2014, Vol. 28, No. 7: 394-395. (Source: AIDS Patient Care and STDs)
Malawi: Mulanje Drills Sports Youths in HIV Prevention and Sports Club Management
[Malawi News Agency]Mulanje -Training sports men in HIV prevention and sports club management is one of the ways of improving sporting activities among youths, Mulanje District sports office has said. (Source: AllAfrica News: HIV-Aids and STDs)
HIV Patients Less Likely to Get Cancer Treatment: Study
Challenges in managing side effects may prompt some doctors to treat tumors less aggressively, researchers suggest (Source: The Doctors Lounge - Oncology)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Zimbabwe: 'Women Fear Pregnancy More Than HIV Infection'
[The Herald]HIV and Aids researchers are looking into possibilities of developing prevention products that can also be used to prevent pregnancies, a local researcher has revealed. (Source: AllAfrica News: HIV-Aids and STDs)
Kenya: Teenagers With HIV Rebel Against Drug Regimen
[Key Correspondents]The defaulter's club in Kenya is not like any other club - it is a growing movement of teenagers born with HIV who deliberately take 'holidays' from their life-saving medication. (Source: AllAfrica News: HIV-Aids and STDs)
Inteleukin-23 Promotes Interferon-? Responsiveness in Hepatitis C Virus/HIV-Coinfected Patients
AIDS Research and Human Retroviruses , Vol. 0, No. 0. (Source: AIDS Research and Human Retroviruses)
HIV Patients Less Likely to Get Cancer Treatment
Challenges in managing side effects may prompt some doctors to treat tumors less aggressively, researchers suggest Source: HealthDay Related MedlinePlus Pages: Cancer, HIV/AIDS (Source: MedlinePlus Health News)
Kenya: Garissa Women Urged to Step Up Fight Against HIV
[The Star]Garissa Governor Nathif Jama's wife, Amina Abdullahi, has urged women in the county to step up the fight against HIV-Aids. HIV contributes to 20 per cent of maternal health, Abdullahi said during the county first lady consultative forum on HIV and Aids on Sunday. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Babies CURED of HIV after being given revolutionary vaccine
The Melbourne AIDS conference, to be held in late July, will look into the success story of the four Canadian newborns who received a high doses of three different antiretroviral drugs as treatment for the virus. (Source: the Mail online | Health)
Kenya: Women Leaders in African Churches Reflect On HIV and Aids
[ACNS]Early struggles in developing a response to the HIV and AIDS pandemic were remembered by African women church leaders who gathered in Nairobi, Kenya to celebrate more than 30 years of their Christian ministry in the churches of their region. (Source: AllAfrica News: HIV-Aids and STDs)
Nigeria: No Cure for HIV Infection Yet - Don
[Leadership]There is neither a cure for an established HIV infection nor a vaccine to prevent people from acquiring the infection, a professor of Medicine, Salami Alakija Kazeem has said. (Source: AllAfrica News: HIV-Aids and STDs)
Children born into families affected by HIV
No abstract available (Source: AIDS)
From patient to person: the need for an ?HIV trajectories? perspective in the delivery of prevention of mother-to-child-transmission services
Accelerated efforts to end vertical HIV transmission have resulted in a 52% decrease in new infections among children since 2001. However, current approaches to prevent mother-to-child-transmission (PMTCT) assume a linearity and universality. These insufficiently guide clinicians and programmes toward interventions that comprehensively address the varying and changing needs of clients. This results in high levels of loss-to-follow-up at each step of the PMTCT cascade. Current PMTCT approaches must be adapted to respond to the different and complex realities of women, children and families affected by HIV.Drawing on the concept of an ?HIV trajectories,? we screened peer-reviewed literature for promising PMTCT approaches and selected 13 articles for qualitative review when the described ...<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Implementation of a safer conception service for HIV-affected couples in South Africa
Conclusions:Lessons learned from early implementation demonstrate feasibility of safer conception services; however, reaching discordant couples, cART-naïve infected partners, and men remain challenges. Creating demand for safer conception services among those at highest risk for HIV transmission is necessary. (Source: AIDS)
Predicting long-term outcomes for children affected by HIV and AIDS: perspectives from the scientific study of children's development
The immediate and short-term consequences of adult HIV for affected children are well documented. Little research has examined the long-term implications of childhood adversity stemming from caregiver HIV infection. Through overviews provided by experts in the field, together with an iterative process of consultation and refinement, we have extracted insights from the broader field of child development of relevance to predicting the long-term consequences to children affected by HIV and AIDS. We focus on what is known about the impact of adversities similar to those experienced by HIV-affected children, and for which there is longitudinal evidence. Cautioning that findings are not directly transferable across children or contexts, we examine findings from the study of parental death, divor...
Cash plus care: social protection cumulatively mitigates HIV-risk behaviour among adolescents in South Africa
This study investigated whether parental AIDS and other environmental adversities increase adolescent HIV-risk behaviour and whether social protection provision of ?cash? or integrated ?cash plus care? reduces HIV-risk behaviour. Design:A prospective observational study with random sampling ( (Source: AIDS)
Early childhood development: promoting the potential of all children
No abstract available (Source: AIDS)
Individualizing the WHO HIV and infant feeding guidelines: optimal breastfeeding duration to maximize infant HIV-free survival
Conclusion:Tailoring breastfeeding duration to maternal CD4+, antiretroviral drug availability, and local replacement feeding safety can optimize HFS among HIV-exposed infants. An individualized approach leads to moderate gains in HFS, but only when mortality risks from replacement feeding are very low or very high, or antiretroviral drug availability is limited. The WHO public health approach is beneficial in most resource-limited settings. (Source: AIDS)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Improving early childhood development outcomes for children affected by HIV and AIDS
No abstract available (Source: AIDS)
If you text them, they will come: using the HIV infant tracking system to improve early infant diagnosis quality and retention in Kenya
Conclusion:The HITSystem maximizes the use of easily accessible technology to improve the quality and efficiency of EID services in resource-limited settings. (Source: AIDS)
Evidence of impact: health, psychological and social effects of adult HIV on children
This study is the first in a series of three commissioned by President's Emergency Plan for AIDS Relief (PEPFAR)/United States Agency for International Development (USAID), the summary provided here was used to inform a second study which seeks to identify insights from the broader child development field which will help us predict what long-term negative consequences children affected by HIV and AIDS are likely to experience. The third study discusses the design of a model to estimate these consequences. Although comprehensive, the review is often hampered by poor-quality research, inadequate design, small sample sizes and single studies in some areas. (Source: AIDS)
PEPFAR: bringing research and practice together for children by predicting long-term outcomes for children affected by AIDS
No abstract available (Source: AIDS)
Modelling the long-term impacts on affected children of adult HIV: benefits, challenges and a possible approach
We outline the benefits, challenges and possible approaches to developing mathematical models that could be used to estimate the magnitude of negative consequences of adult HIV infection for children. Adult HIV infection can lead to numerous negative consequences for dependent children, including depression, anxiety, withdrawal from school and early sexual debut, among others. For advocacy and planning purposes, it is important to highlight and consider as many of these as possible. A focus solely on orphan numbers, which is the typical summary measure for children affected by HIV and AIDS, can be misleading. The complexity of child development that is characterized by the interaction of a multitude of proximal and distal factors, coupled with a significant lack of data on child developmen...<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
The contribution of schools to supporting the well being of children affected by HIV in eastern Zimbabwe
Conclusions:General and HIV-specific school quality may enhance the well being of primary school-age children in eastern Zimbabwe. Local community context also plays an important role in child well being. (Source: AIDS)
Cognitive and language outcomes in HIV-uninfected infants exposed to combined antiretroviral therapy in utero and through extended breast-feeding
Objective:To determine whether there is a higher risk for cognitive or language delay among HIV-exposed uninfected (HEU) children exposed to cART (zidovudine/lamivudine/lopinavir/ritonavir) in utero and through 1 year of breast-feeding (World health Organization Option B+), compared with the control children born to HIV-uninfected mothers. Design:This is a double cohort study from Lusaka, Zambia. Methods:HEU (n?=?97) and control (n?=?103) children aged 15?36 months were assessed on their early nonverbal problem-solving and language skills using the standardized Capute Scales. A score of less than 85 on the Capute Full-Scale Developmental Quotient (FSDQ) was considered indicative of developmental delay and was the primary outcome of interest. Results:An FSDQ of less than 85 was fo...
A randomized clinical trial of an intervention to promote resilience in young children of HIV-positive mothers in South Africa
Conclusion:This is the first study demonstrating benefits of an intervention designed to promote resilience among young children of HIV-positive mothers. The intervention was specifically designed for an African context and has the potential to benefit large numbers of children, if it can be widely implemented. (Source: AIDS)
The role of perceived social support in loneliness and self-esteem among children affected by HIV/AIDS: a longitudinal multilevel analysis in rural China
Conclusions:The positive effect of PSS on psychological adjustment may imply a promising approach for future intervention among children affected by HIV/AIDS, in which efforts to promote psychosocial well being could focus on children and families with lower social support. We also call for a greater understanding of children's psychological adjustment process in various contexts of social support and appropriate adaptations of evidence-based interventions to meet their diverse needs. (Source: AIDS)
Maternal HIV disclosure to young HIV-uninfected children: an evaluation of a family-centred intervention in South Africa
Conclusions:This intervention is acceptable in resource-limited settings and shows promise. Further research using a controlled design is needed to test this intervention. (Source: AIDS)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
German cohort of HCV mono-infected and HCV/HIV co-infected patients reveals relative under-treatment of co-infected patients
Conclusion: Overall, treatment was only initiated in half of the patients of the entire cohort and in an even smaller proportion of HCV/HIV co-infected patients despite comparable outcome (SVR) and similar baseline characteristics. In the light of newer treatment options, greater efforts to remove the barriers to treatment that still exist for a great proportion of patients especially with HIV/HCV co-infection have to be undertaken. (Source: AIDS Research and Therapy)
Review: Hippocampal sclerosis in epilepsy: a neuropathology review
Hippocampal sclerosis (HS) is a common pathology encountered in mesial temporal lobe epilepsy (MTLE) as well as other epilepsy syndromes and in both surgical and post?mortem practice. The 2013 International League Against Epilepsy (ILAE) classification segregates HS into typical (type 1) and atypical (type 2 and 3) groups, based on the histological patterns of subfield neuronal loss and gliosis. In addition, granule cell reorganization and alterations of interneuronal populations, neuropeptide fibre networks and mossy fibre sprouting are distinctive features of HS associated with epilepsies; they can be useful diagnostic aids to discriminate from other causes of HS, as well as highlighting potential mechanisms of hippocampal epileptogenesis. The cause of HS remains elusive and may be mul...
The politics of agenda setting at the global level: key informant interviews regarding the International Labour Organization Decent Work Agenda
Conclusions: Our evidence aids our understanding of how an issue like decent work enters and stays on the policy agendas of global institutions, using the Decent Work Agenda as an illustrative example. Catalytic events and policy precedents were found to contribute positively to agenda setting. Questions remain, however, across key informants about the robustness of the underlying evidence base for this Agenda and what meaningful impacts have been realized on the ground as a result. (Source: Globalization and Health)
Task shifting from doctors to non-doctors for initiation and maintenance of antiretroviral therapy.
CONCLUSIONS: Our review found moderate quality evidence that shifting responsibility from doctors to adequately trained and supported nurses or community health workers for managing HIV patients probably does not decrease the quality of care and, in the case of nurse initiated care, may decrease the numbers of patients lost to follow-up. PMID: 24980859 [PubMed - as supplied by publisher] (Source: Cochrane Database of Systematic Reviews)
Symptoms, coping, and quality of life in pediatric brain tumor survivors: a qualitative study.
Conclusions: Survivors experienced multiple symptoms that had an effect on their life, but overall, they described good QOL.Interpretation: Caregivers need to understand the complexity of their patient's symptom experience and its impact on his or her daily life. Coping strategies can be identified to help mitigate potentially negative QOL outcomes. PMID: 24969249 [PubMed - in process] (Source: Oncology Nursing Forum)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Addressing sexual health behaviour during emerging adulthood: a critical review of the literature
ConclusionsGrowing evidence demonstrates sexual health interventions may be more effective if augmented to attend to contextual and affective influences on relationship risks and decision?making. Modifying currently accepted strategies may enhance sustainability of sexual health?promoting behaviours. Relevance to clinical practiceThis study provides nurses and public health educators with recommendations for broadening the content of sexual health promotion intervention programming. (Source: Journal of Clinical Nursing)
Shoulder Instability in Older Patients.
Authors: Paxton ES, Dodson CC, Lazarus MD Abstract Glenohumeral instability has a bimodal age distribution, with most affected patients younger than 40 years, but with a second peak in older patients. Glenohumeral dislocations in older patients often present with complex injury patterns, including rotator cuff tears, fractures, and neurovascular injuries. Glenohumeral instability in patients older than 40 years requires a different approach to treatment. An algorithmic approach aids the surgeon in the stepwise decision-making process necessary to treat this injury pattern. PMID: 24975764 [PubMed - as supplied by publisher] (Source: The Orthopedic Clinics of North America)
Association Between Efavirenz as Initial Therapy for HIV-1 Infection and Increased Risk for Suicidal Ideation or Attempted or Completed Suicide: An Analysis of Trial Data.
CONCLUSION: Initial treatment with an efavirenz-containing antiretroviral regimen was associated with a 2-fold increased hazard of suicidality compared with a regimen without efavirenz. PRIMARY FUNDING SOURCE: National Institutes of Health. PMID: 24979445 [PubMed - in process] (Source: Annals of Internal Medicine)
Aging with hiv infection: a journey to the center of inflammaids, immunosenescence and neurohiv.
AGING WITH HIV INFECTION: A JOURNEY TO THE CENTER OF INFLAMMAIDS, IMMUNOSENESCENCE AND NEUROHIV. Immunol Lett. 2014 Jul 1; Authors: Nasi M, Pinti M, De Biasi S, Gibellini L, Ferraro D, Mussini C, Cossarizza A Abstract In the last years, a significant improvement in life expectancy of HIV+ patients has been observed in Western countries. The parallel increase in the mean age of these patients causes a parallel increase in the frequency of non-AIDS related complications (i.e., neurocognitive, cardiovascular, liver and kidney diseases, metabolic syndrome, osteoporosis, and non-HIV associated cancers, among others), even when antiviral treatment is successful. Immune activation and persistent inflammation characterizes both HIV infection and physiological aging, and both c...
Management of Right Heart Failure in the Critically Ill
Right ventricular failure complicates several commonly encountered conditions in the intensive care unit. Right ventricular dilation and paradoxic movement of the interventricular septum on echocardiography establishes the diagnosis. Right heart catheterization is useful in establishing the specific cause and aids clinicians in management. Principles of treatment focus on reversal of the underlying cause, optimization of right ventricular preload and contractility, and reduction of right ventricular afterload. Mechanical support with right ventricular assist device or veno-arterial extracorporeal membrane oxygenation can be used in select patients who fail to improve with optimal medical therapy. (Source: Critical Care Clinics)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Luc's abscess as an unlucky complication of mastoiditis.
We present the case of a patient with a Luc's abscess with mastoid involvement and discuss its successful management. We believe that patients presenting with a subperiosteal collection beneath the temporal muscle and mastoiditis may represent a different group of patients to those described originally by Luc. These individuals can be differentiated using computed tomography (CT) of the temporal bones. We advocate CT in patients with Luc's abscess and AOM; this aids preoperative surgical planning. PMID: 24992410 [PubMed - in process] (Source: Annals of the Royal College of Surgeons of England)
Ototoxicity in Nigeria: Why it persists.
Authors: Kokong DD, Bakari A, Ahmad BM Abstract No therapy is currently available to reverse the serious damage that can be caused by ototoxic drugs, such as permanent hearing loss and balance disorders. Otolaryngologists in various regions of the world have developed strategies aimed at curtailing drug-induced ototoxicity, but similar efforts in most developing nations have yet to be well established. We conducted a study to document our experience in Nigeria. Our study population was made up of 156 patients-66 males and 90 females, aged 5 to 85 years (mean: 32.1 ± 30.7)-who were diagnosed with drug-induced ototoxicity over a 3-year period. Tinnitus was the first and the predominant symptom in 140 patients (89.7%). The most common cause of drug-induced ototoxicity among the 156 p...
Effect of domestic violence training: Systematic review of randomized controlled trials.
CONCLUSION: It was difficult to determine the most effective educational strategy, as the educational interventions and the outcome measures varied among the selected studies. Brief interventions for postgraduate trainee physicians improved knowledge but did not seem to affect behaviour. Online education using a problem-based learning format improved practising physicians' perceptions, knowledge, and skills in managing domestic violence. Physician training combined with system support interventions seemed to benefit domestic violence victims and increase referrals to domestic violence support resources. PMID: 25022633 [PubMed - as supplied by publisher] (Source: Canadian Family Physician Medecin de Famille Canadien)
Masthead
(Source: Journal of the Association of Nurses in AIDS Care)
Board of Directors
(Source: Journal of the Association of Nurses in AIDS Care)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Table of Contents
(Source: Journal of the Association of Nurses in AIDS Care)
Editorial Board
(Source: Journal of the Association of Nurses in AIDS Care)
Cover 1
(Source: Journal of the Association of Nurses in AIDS Care)
Simplified Submission
(Source: Journal of the Association of Nurses in AIDS Care)
Pursuing Meaning and Purpose in Life Among Thai Adolescents Living With HIV: A Grounded Theory Study
(Source: Journal of the Association of Nurses in AIDS Care)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Side effects and tolerability of post-exposure prophylaxis with zidovudine, lamivudine, and lopinavir/ritonavir: a comparative study with HIV/AIDS patients.
CONCLUSION: HCPs who received occupational PEP with triple-drug regimen, AZT+3TC+Lpv/r, experienced different side effects, and the tolerability and safety of PEP regimen were good in this cohort. PMID: 25043080 [PubMed - in process] (Source: Chinese Medical Journal)
Is an Appropriate Wheelchair Becoming out of Reach?
Never before has the world been more replete with technological aids for people with disabilities: high-performing prosthetics; accessible computer devices; environmental control units; wheelchairs that can recline, stand, and climb curbs; and laptop-sized ventilators to name just a few devices. Such tools can make the difference between people with physical disabilities living in their own homes, participating in their communities, and being engaged in the workforce versus being confined to an institution, or an inaccessible home and even to bed. Yet, just as Tantalus in Homer's Odyssey stood immersed chest high in water beneath a tree laden with ripe fruit, he could neither quench his hunger nor thirst. As he would reach up to grasp, or bend down to drink, the fruit and water would move ...
Using an Emergency Department Syndromic Surveillance System to investigate the impact of extreme cold weather events
This report describes the development of novel syndromic cold weather public health surveillance indicators for use in monitoring the impact of extreme cold weather on attendances at EDs, using data from the 2010?11 and 2011?12 winters.A number of new surveillance indicators were created specifically for the identification and monitoring of cold weather related ED attendances, using the diagnosis codes provided for each attendance in the Emergency Department Syndromic Surveillance System (EDSSS), the first national syndromic surveillance system of its kind in the UK. Using daily weather data for the local area, a time series analysis to test the sensitivity of each indicator to cold weather was undertaken.Diagnosis codes relating to a health outcome with a potential direct link to cold...
Common HIV Drug May Boost Suicide Risk
Patients taking efavirenz should be assessed for depression, researchers saySource: HealthDay Related MedlinePlus Pages: Depression, HIV/AIDS Medicines, Suicide (Source: MedlinePlus Health News)
HIV Prevention Drug Truvada Might Lower Genital Herpes Risk, Too
But effect isn't strong enough to make it a stand-alone preventive treatment for herpes, expert saysSource: HealthDay Related MedlinePlus Pages: Genital Herpes, HIV/AIDS Medicines (Source: MedlinePlus Health News)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Shoulder Instability in Older Patients
Glenohumeral instability has a bimodal age distribution, with most affected patients younger than 40 years, but with a second peak in older patients. Glenohumeral dislocations in older patients often present with complex injury patterns, including rotator cuff tears, fractures, and neurovascular injuries. Glenohumeral instability in patients older than 40 years requires a different approach to treatment. An algorithmic approach aids the surgeon in the stepwise decision-making process necessary to treat this injury pattern. (Source: Orthopedic Clinics of North America)
Egypt: Armed Forces Postpone Virus C, Aids Treatment for 6 Months
[Egypt Online]Head of the medical department in the Armed Forces Major General Gamal el-Sirafi said that the treatment for virus C and AIDS diseases by newly-invented devices of the Armed Forces will be postponed for six months. (Source: AllAfrica News: HIV-Aids and STDs)
Nigeria: '300 Babies Born HIV-Free By Infected Mothers'
[Daily Trust]Ilorin -Over 300 HIV infected expectant mothers have so far delivered their babies free of the virus with the assistance of the HIV/AIDS management centre of the University of Ilorin Teaching Hospital (UITH). (Source: AllAfrica News: HIV-Aids and STDs)
Nigeria: HIV/Aids - Benue Translates Anti-Stigma Law
[Daily Trust]Makurdi -The Benue State AIDS Control Agency (BENSACA) has translated the HIV/AIDS anti-stigma law which came into existence early this year into three major languages for wider dissemination. (Source: AllAfrica News: HIV-Aids and STDs)
Booze, the Brain and Sleep
Alcohol is often used by many people to help them sleep. Because it initially helps to relax and feel sleepy, it seems to work. This is because alcohol promotes reduced tension, shortens the time to fall asleep and increases deep sleep. Unfortunately, later in the night the effects are different and sleep is disrupted and lighter, resulting in overall poor quality sleep.read more (Source: Psychology Today Addiction Center)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Nigeria: Govt, Labour Partner to Tackle HIV, Aids Pandemic
[Independent]The Nigeria Labour Congress (NLC) in collaboration with the Canadian Labour Congress and International Confederation of Trade Union/Africa, as well as the Federal Government and employer representatives in Nigeria to reduce the HIV/AIDS pandemic in the workplace. (Source: AllAfrica News: HIV-Aids and STDs)
Namibia: A Decade of Living Positively With HIV
[New Era]Ongwediva -A woman from Oshikoto Region, Helena Hatutale, has lived positively with HIV for the past ten years and is still going strong. (Source: AllAfrica News: HIV-Aids and STDs)
Kenya: Ojaamong's Wife Fights Busia HIV
[The Star]THE Busia county assembly Budget and Appropriation Committee has reduced personnel costs in the 2014-15 financial year. (Source: AllAfrica News: HIV-Aids and STDs)
Tanzania: Moshi Grapples With HIV As Donors Call It Quits
[Daily News]Moshi -MOSHI Rural District is not excluded from the list of areas in the country where the rate of HIV infection is rising. Currently, the HIV infection rate in the district stands at 2.1 per cent, up from 1.3 per cent recorded in 2012 from voluntary testing. (Source: AllAfrica News: HIV-Aids and STDs)
Centers Provide Model for HIV Testing in Community SettingCenters Provide Model for HIV Testing in Community Setting
Centers in New York and New Orleans provide model approaches to increasing HIV testing and linkage to care. Medscape Medical News (Source: Medscape Medical News Headlines)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Nigeria: Agency Battles Aids With N69 Million
[Independent]Katsina -Katsina State Agency for the Control of AIDS (SACA) has disbursed over N69 million to 25 non-governmental organizations for the fight against AIDS. (Source: AllAfrica News: Health and Medicine)
Nigeria: 3.5 Million Nigerians Still Living With HIV - Don
[Independent]Ilorin -Kazeem, has said that the Acquired Immune Deficiency Syndrome (AIDS) related death has increased in the country in recent time owing to inability of the nation to attain expected target in the treatment of the health crisis. (Source: AllAfrica News: Health and Medicine)
HIV Prevention Drug Truvada Might Lower Genital Herpes Risk, Too
But effect isn't strong enough to make it a stand-alone preventive treatment for herpes, expert says (Source: Fertility News - Doctors Lounge)
Evaluating protocol lifecycle time intervals in HIV/AIDS clinical trials.
CONCLUSION: Delays not only increase the time and cost to complete clinical trials but they also diminish their usefulness by failing to answer research questions in time. We believe that research analyzing the time spent traversing defined intervals across the clinical trial protocol development and implementation continuum can stimulate business process analyses and re-engineering efforts that could lead to reductions in the time from clinical trial concept to results, thereby accelerating progress in clinical research. PMID: 24980279 [PubMed - as supplied by publisher] (Source: Clinical Trials)
Protein-protein interactions and human cellular cofactors as new targets for HIV therapy.
Authors: Tintori C, Brai A, Fallacara AL, Fazi R, Schenone S, Botta M Abstract Two novel approaches for the development of new drugs against AIDS are summarized each leading to the achievement of important discoveries in anti-HIV therapy. Despite the success of HAART in reducing mortality, resistant strains continue to emerge in the clinic, underscoring the importance of developing next-generation drugs. Protein-protein interactions and human cellular cofactors represent the new targets of tomorrow in HIV research. The most relevant results obtained in the last few years by the two new strategies are described herein. PMID: 24993074 [PubMed - as supplied by publisher] (Source: Current Opinion in Pharmacology)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
HIV vaccine inventor indicted for felony fraud, bringing AIDS research and drug experimentation into question
(NaturalNews) Since the discovery of lymphadenopathy-associated virus (later called human immunodeficiency virus [HIV]) in 1983 by Luc Montagnier at the Pasteur Institute in France, scientists have attempted to understand how HIV leads to full-blown AIDS. An entire industry surrounding... (Source: NaturalNews.com)
Cuomo Plan Seeks to End New York?s AIDS Epidemic
Gov. Andrew M. Cuomo said he would announce on Sunday a plan for more-aggressive testing and treatment, a result of months of negotiations with AIDS activists. (Source: NYT Health)
Risk prediction tools in surgical oncology
This article discusses decision aids for surgical oncology patients. Topics include: short?term risk prediction following surgery, long?term risk prediction of survival and recurrence, the combination of short? and long?term risk prediction to help guide treatment choice, and decision aid usability, transparency, and accessibility. J. Surg. Oncol. © 2014 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology)
Zinc finger nuclease: a new approach for excising HIV-1 proviral DNA from infected human T cells.
Authors: Qu X, Wang P, Ding D, Wang X, Zhang G, Zhou X, Liu L, Zhu X, Zeng H, Zhu H Abstract A major reason that Acquired Immune Deficiency Syndrome (AIDS) cannot be completely cured is the human immunodeficiency virus 1 (HIV-1) provirus integrated into the human genome. Though existing therapies can inhibit replication of HIV-1, they cannot eradicate it. A molecular therapy gains popularity due to its specifically targeting to HIV-1 infected cells and effectively removing the HIV-1, regardless of viral genes being active or dormant. Now, we propose a new method which can excellently delete the HIV provirus from the infected human T cell genome. First, we designed zinc-finger nucleases (ZFNs) that target a sequence within the long terminal repeat (LTR) U3 region that is highly cons...
Cuomo Plan Seeks to End New York?s AIDS Epidemic
Gov. Andrew M. Cuomo said he would announce on Sunday a plan for more-aggressive testing and treatment, a result of months of negotiations with AIDS activists. (Source: NYT)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Fetal aortic valvuloplasty: investigating institutional bias in surgical decision making.
CONCLUSIONS: This method may improve interpretation of outcomes in multicentre studies by identifying and investigating outliers identified in funnel plots. PMID: 24975801 [PubMed - as supplied by publisher] (Source: The Ultrasound Review of Obstetrics and Gynecology)
Enhanced oral bioavailability of nevirapine within micellar nanocarriers compared with Viramune(®)
Authors: Moretton MA, Cohen L, Lepera L, Bernabeu E, Taira C, Höcht C, Chiappetta DA Abstract In this work, Nevirapine (NVP) was encapsulated within three derivatives of poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) (PEO-PPO-PEO) block copolymers (Tetronic(®) 904, 1107 and Pluronic(®) F127) with and without the addition of three pharmaceutical cosolvents (glycerin, propylene glycol and polyethylene glycol 400) over a wider range of concentrations (0-40% v/v). Also, we evaluated the effect of addition of the cosolvents on the micellar size as determined by dynamic light scattering (DLS) measurements and transmission electron microscopy (TEM). The solubilization capacity of the systems was investigated by UV-spectrophotometry (282nm) and the systems stability was...
[Clinical validity of the quantitative gait variables in patients with multiple sclerosis. A comparison of the Timed 25-foot Walk Test and the GAITRite ® Electronic Walkway system].
CONCLUSIONS. GEW system has the same clinical validity in gait evaluation in multiple sclerosis patients than the T25FW. PMID: 24965925 [PubMed - in process] (Source: Revista de Neurologia)
EU Panel Gives Nod to Triple Combo Pill for HIV (Triumeq) EU Panel Gives Nod to Triple Combo Pill for HIV (Triumeq)
The EU?s Committee for Medicinal Products for Human Use has given a positive opinion for marketing of Triumeq, a once-daily combination of the antivirals dolutegravir, abacavir, and lamivudine. International Approvals (Source: Medscape Medical News Headlines)
Emory group creates Atlanta AIDS map by ZIP code
A project developed in part by Emory University?s Rollins School of Public Health has released interactive online maps that show the prevalence of HIV in 22 U.S. cities, including Atlanta. AIDSVu aggregates data by ZIP code, as well as age, race and sex, which shows the data alongside various social determinants of health, including poverty, median household income and education. It also offers HIV testing and care services locator maps. The project?s nationwide map shows higher rates of people? (Source: bizjournals.com Health Care:Biotechnology headlines)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Men at High Risk for HIV May Misjudge Their VulnerabilityMen at High Risk for HIV May Misjudge Their Vulnerability
Many gay, bisexual and queer men who are good candidates for pre-exposure prophylaxis of HIV don't believe their risk of infection is high enough to warrant using it, suggests a new study. Reuters Health Information (Source: Medscape Hiv-Aids Headlines)
Nucleic acid testing of hepatitis B virus, hepatitis C virus, and human immunodeficiency virus 1, 2 in blood donors in the General University Hospital, Prague.
Authors: Du?ková D, Darební?ek L Abstract The Roche Cobas TaqScreen MPX Test v1 - multiplex reverse transcription-real time (MPX RT-Real Time) PCR, performed on Cobas s201 for HCV RNA, HBV DNA, HIV-1 RNA /group M and O/, and HIV-2 RNA was introduced as a supplement to the currently used imunoanalysis method for blood donor´s testing (Abbott CMIA - chemiluminescent microparticle imunoassay, performed on Architect i2000 for anti-HCV, hepatitis B surface antigen (HBsAg)), anti-HIV-1 /group M and O/, anti-HIV-2 and p24 HIV). The results of study could provide valuable arguments to support the discussion about the NAT implementation into the standards of blood donor´s testing in the Czech Republic. Two groups of samples were tested. In the first one, 5074 samples from consecuti...
Ed Goldman: How one executive beat a chronic illness and joined a marathon bike ride
?I didn?t know the trip was going to be 545 miles,? Scott Thiede is telling me, the implicit add-on being that he must have been crazy to undertake it. What he undertook early this month was a weeklong, 545-mile bike ride from San Francisco to Los Angeles to raise money and visibility for HIV/AIDS. As of mid-month, Bank of America?s team of 45-40 riders and five ?roadies? to help with equipment and such ? had raised nearly $233,000 for the San Francisco AIDS Foundation and Los Angeles? (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Cerebrospinal fluid metabolomics reveals altered waste clearance and accelerated aging in HIV patients with neurocognitive impairment
Conclusions:Alterations in the CSF metabolome of HIV patients on ART suggest that persistent inflammation, glial responses, glutamate neurotoxicity, and altered brain waste disposal systems contribute to mechanisms involved in HAND that may be augmented with aging. (Source: AIDS)
Africa: Maternal Deaths Due to HIV a Grim Reality
[IPS]Nairobi -An African proverb says that every woman who gives birth has one foot on her grave. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Kenya: Study Reveals Kenyan Men Are Ignorant of HIV-Aids Risk
[The Star]RESULTS from the Kenya Aids Indicator Survey that was released on Wednesday show more men than women perceiving themselves to be at low risk of contracting HIV-Aids, despite the prevailing high risk. (Source: AllAfrica News: HIV-Aids and STDs)
Kenya: Concern Over Infected Babies
[The Star]FEAR of more HIV-Aids infections have increased in Embu due to failure by about half of the infected pregnant women to deliver in hospitals (Source: AllAfrica News: Pregnancy and Childbirth)
Kenya: Agency Fights HIV-Aids in Northern Kenya
[The Star]RESIDENTS of Garissa have been encouraged to participate in implementation of HIV-Aids activities. (Source: AllAfrica News: HIV-Aids and STDs)
Kenya: NACC Asks for More Funds
[The Star]THE county government should allocate more funds to the health sector to help fight HIV/Aids, the National Aids Control Council has said. (Source: AllAfrica News: HIV-Aids and STDs)
Sierra Leone: Aids Secretariat Sensitizes Women On Reproductive Health
[Concord]The National HIV/AIDS Secretariat has engaged women living with HIV in a two-day awareness raising programme held at the conference hall of the Council of Churches in Sierra Leone, Kingharman Road in Freetown. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Kenya: Kenya Sex Worker Study Looks for Answers to the HIV Menace
[GFO]The Global Fund is supporting an investigation into behavior and attitudes towards HIV in this at-risk population (Source: AllAfrica News: HIV-Aids and STDs)
Kenya: In Western Kenya, Modest Inroads Being Made Against Fear and Ignorance About HIV and Sex Work
[GFO]The red-light district in Kisii, on the shores of Lake Victoria in western Kenya, isn't much of a tourist destination; its narrow roads are lined with shacks and shops and maybe a gathering spot or two where the offerings are locally brewed beer and roasted goat meat, with a football match blaring from a TV mounted in the corner. (Source: AllAfrica News: HIV-Aids and STDs)
Maternal Deaths Due to HIV a Grim Reality
According to an African proverb, ?every woman who gives birth has one foot on her grave.? It is time to make this proverb a historical fact and not a present reality. Credit: Mercedes Sayagues/IPSBy Miriam GathigahNAIROBI, Jun 27 2014 (IPS) An African proverb says that every woman who gives birth has one foot on her grave. Sadly, this is still true today, especially within the context of the AIDS epidemic. In spite of the huge advances in the prevention of mother to child transmission of HIV (PMTCT) in Africa, experts are concerned that these have not matched other pillars needed to eliminate maternal mortality caused by HIV and AIDS. Preventing unintended pregnancies among women living HIV, as well as providing contraceptives for women who need them are some of the missing pillars. A...
Pill to Prevent AIDS?
What can you tell me about Truvada, the pill recommended to prevent AIDS? Who should take it? I thought abstinence or using condoms were the only ways to prevent AIDS. Is that no longer the case? (Source: Dr. Weil Q and A)
Deferred ART Could Improve Survival in HIV Meningitis Deferred ART Could Improve Survival in HIV Meningitis
Patients with HIV and cryptococcal meningitis have better survival when they receive deferred ART compared with earlier ART. Medscape Medical News (Source: Medscape Medical News Headlines)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Namibia: Namibia Has Impressive ARV Coverage
[New Era]Windhoek -Namibia is one of the African countries enjoying remarkable coverage of life-saving antiretroviral (ARV) treatment, with about 90 percent of Namibians living with HIV and AIDS receiving ARVs from the state. (Source: AllAfrica News: HIV-Aids and STDs)
Prevalence and Risk Factors for Human T Cell Lymphotropic Virus Infection in Southern Brazilian HIV-Positive Patients
AIDS Research and Human Retroviruses , Vol. 0, No. 0. (Source: AIDS Research and Human Retroviruses)
Using verbal and social autopsies to explore health-seeking behaviour among HIV-positive women in Kenya: a retrospective study
Conclusions: The findings highlight important issues that have implications for addressing challenges faced by women living with HIV, including non-adherence to treatment regimen and late diagnosis of HIV. Provision of transportation subsidies as part of the national social safety-net strategy can help in addressing financial constraints associated with transportation costs among poor women living with HIV. (Source: BMC Women's Health - Latest articles)
Genetic analysis of an allergic rhinitis cohort reveals an intercellular epistasis between FAM134B and CD39
Conclusions: The interplay between promoter SNPs of CD39 and FAM134B results in an intercellular epistasis which influences the risk of a complex inflammatory disease. (Source: BMC Medical Genetics - Latest articles)
Nail psoriasis: The journey so far
Alka Dogra, Amanjot Kaur AroraIndian Journal of Dermatology 2014 59(4):319-333Nail involvement is an extremely common feature of psoriasis and affects approximately 10-78&#x0025; of psoriasis patients with 5-10&#x0025; of patients having isolated nail psoriasis. However, it is often an overlooked feature in the management of nail psoriasis, despite the significant burden it places on the patients as a result of functional impairment of manual dexterity, pain, and psychological stress. Affected nail plates often thicken and crumble, and because they are very visible, patients tend to avoid normal day-to-day activities and social interactions. Importantly, 70-80&#x0025; of patients with psoriatic arthritis have nail psoriasis. In this overview, we review the clinical manifestations of psoria...<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
New CDC HIV Testing Recommendations Offer Faster DiagnosisNew CDC HIV Testing Recommendations Offer Faster Diagnosis
Adopting the new recommendations will lead to HIV diagnosis as much as 3 to 4 weeks sooner than the previous testing approach, the CDC says. Medscape Medical News (Source: Medscape Medical News Headlines)
Laboratory Testing for the Diagnosis of HIV Infection: Updated Recommendations
This document updates recommendations for HIV testing by laboratories in the United States and offers approaches for reporting test results to persons ordering HIV tests and to public health authorities. In brief, testing begins with a combination immunoassay that detects HIV-1 and HIV-2 antibodies and HIV-1 p24 antigen. All specimens reactive on this initial assay undergo supplemental testing with an immunoassay that differentiates HIV-1 from HIV-2 antibodies. Specimens that are reactive on the initial immunoassay and nonreactive or indeterminate on the antibody differentiation assay proceed to HIV-1 nucleic acid testing for resolution. (Source: CDC HIV/AIDS Prevention)
Quick Reference: Recommended Laboratory HIV Testing Algorithm for Serum or Plasma Specimens
This document provides a snap shot of the updated recommendations for laboratory testing for the diagnosis of HIV infection. (Source: CDC HIV/AIDS Prevention)
MMWR: Routine HIV Screening in Two Health-Care Settings ? New York City and New Orleans, 2011?2013
Approximately 16% of the estimated 1.1 million persons living with HIV in the United States are unaware of their infection and thus unable to benefit from effective treatment. Since 2006, CDC has recommended health-care providers screen all patients aged 13?64 years for HIV, unless prevalence of undiagnosed HIV infection has been documented to be (Source: CDC HIV/AIDS Prevention)
CDC recommends combo HIV test for faster detection of virus
(Reuters) - The U.S. Centers for Disease Control and Prevention (CDC) said on Thursday it has recommended a new type of HIV testing that utilizes diagnostics that can detect infection up to three to four weeks faster, potentially preventing the spread of the virus that causes AIDS. (Source: Reuters: Health)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
[Does routine outcome monitoring have a promising future? An investigation into the use of shared decision-making combined with ROM for patients with a combination of physical and psychiatric symptoms].
CONCLUSION: ROM combined with sdm can be used successfully with patients who have a combination of physical and psychiatric symptoms and the technique can be applied by the professional in charge. Very few patients dropped out of the follow-up measurements and somatic as well as depressive or psychiatric symptoms diminished significantly. These findings indicate that a Randomised Clinical Trial is warranted in order to test the effectiveness of sdm combined with ROM as a decision-making instrument. PMID: 24953511 [PubMed - in process] (Source: Tijdschrift voor Psychiatrie)
Many Unaware of Their HIV Status Until It's Advanced
ER study also finds high proportion without health insurance Source: HealthDay Related MedlinePlus Pages: Emergency Medical Services, HIV/AIDS (Source: MedlinePlus Health News)
The Immune Space: A Concept and Template for Rationalizing Vaccine Development
AIDS Research and Human Retroviruses , Vol. 0, No. 0. (Source: AIDS Research and Human Retroviruses)
High-Fat Meals Do Not Impair Postprandial Endothelial Function in HIV-Infected and Uninfected Men
AIDS Research and Human Retroviruses , Vol. 0, No. 0. (Source: AIDS Research and Human Retroviruses)
Africa: For Mercy Amba Oduyoye, HIV and Aids Are Crucial to Ministry
[WCC]A Methodist theologian from Ghana and former World Council of Churches (WCC) deputy general secretary known for promoting and elevating African women's theological work on gender, ecumenism and social justice was honoured at a recent conference on African women church leaders in Limuru, Kenya. (Source: AllAfrica News: Health and Medicine)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Zimbabwe: Boss Rapes Subordinate, Infects Her With HIV
[The Herald]A 25-YEAR-OLD woman is now jobless and without a husband following a rape attack that robbed her of virginity and left her HIV positive. (Source: AllAfrica News: HIV-Aids and STDs)
Kenya: HIV-Aids Infection Rate Down, Says Macharia
[The Star]THE national HIV-Aids prevalence has dropped from 7.2 in 2007-08 to 5.6 in 2012-13, according to the Kenya Aids Indicator Survey. (Source: AllAfrica News: HIV-Aids and STDs)
A pregnancy hormone molecule can fight cancer (Nature World News, 25 June 2014)
Canadian researchers have presented a study at ICE/ENDO 2014 describing a compound that aids human chorionic gonadotropin (hCG) in fighting cancer, including the incurable Kaposi&rsquo;s sarcoma. Full article (Source: Society for Endocrinology)
Zimbabwe: STIs, 'Mujuru Flies' Rock Tk Mukosi Camp
[New Zimbabwe]THE Chingwizi Transit Camp, temporary home to 3,000 families displaced by Tokwe Mukosi floods, has been hit by an outbreak of sexually transmitted infections (STI) with living conditions reportedly getting ever more desperate. (Source: AllAfrica News: HIV-Aids and STDs)
Kenya: Thousands of Young People Have HIV
[The Star]More than 200 thousand children below 14 years are infected with HIV. UNESCO's Jane Kamau also says nearly 200 thousand of those aged between 15 and 24 years have the virus. She says the country needs to address HIV, especially among the youth. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Eritrea: Eritrean National Association of Citizens Living With HIV/Aids Holds 4th Conference
[Shabait]Asmara -The Eritrean National Association of citizens living with HIV/AIDS held 4th conference on the 24th and 25th of this month at Orotta Hospital hall here in the capital. (Source: AllAfrica News: HIV-Aids and STDs)
Aging with HIV and AIDS: A growing social issue
(Source: St. Michael's Hospital News and Media)
School leaders, staff, students step out in support of AIDS Walk San Francisco
The entire UCSF enterprise&mdash;including the School of Pharmacy&mdash;is gearing up for AIDS Walk San Francisco. This year&rsquo;s walk will take place on Sunday, July 20 in Golden Gate Park. Michael Nordberg, associate dean for finance and administration, is the leader of the 2014 School of Pharmacy Team. Nordberg encourages everyone in the School to join in&mdash;administrators, leaders, faculty, staff, and students. (Source: UCSF School of Pharmacy News)
Does Your State Mandate Hearing Aid Coverage? Laws vary by state?some mandate insurance coverage for hearing aids, some require it only for children, and some require no coverage at all.
Sixteen states require health benefit plans to pay for children?s hearing aids. Only three states?Arkansas, New Hampshire and Rhode Island?require coverage for children and adults. And Wisconsin requires coverage for both hearing aids and cochlear implants for children. (Source: The ASHA Leader Online)
Getting Back to Life Clients retreat from the world when hearing aids stay in the drawer. Moving them forward to adoption and social connection often takes ongoing audiologic follow-up, or rehab. But how does an audiologist do this when clients resist and clocks tick?
(Source: The ASHA Leader Online)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Incontinence?associated dermatitis: a cross?sectional prevalence study in the Australian acute care hospital setting
Abstract The purpose of this cross?sectional study was to identify the prevalence of incontinence and incontinence?associated dermatitis (IAD) in Australian acute care patients and to describe the products worn to manage incontinence, and those provided at the bedside for perineal skin care. Data on 376 inpatients were collected over 2?days at a major Australian teaching hospital. The mean age of the sample group was 62?years and 52% of the patients were male. The prevalence rate of incontinence was 24% (91/376). Urinary incontinence was significantly more prevalent in females (10%) than males (6%) (?2?=?4·458, df?=?1, P?=?0·035). IAD occurred in 10% (38/376) of the sample group, with 42% (38/91) of incontinent patients having IAD. Semi?formed and liquid stool were...
A Process Evaluation of an HIV/STI Intervention for Rural African American Youth
We evaluated the fidelity and implementation of an HIV/AIDS and sexually transmitted infections intervention for rural African American youth. Using a community-based evaluation approach, community partners and researchers monitored four core process-evaluation components: reach, fidelity, dose delivered, and dose received. Researchers collected evaluation data through session observations, facilitator debriefing interviews, a youth focus group, and a satisfaction survey. For reach, more than half of the participants attended the 13 sessions. Participation varied between 62% and 100%. For fidelity, not all sessions were implemented as intended; multiple modifications occurred across sessions. For dose delivered, some lessons were missing materials and content was omitted; facilitators omit...
Do Adolescent Smokers Use E-Cigarettes to Help Them Quit? The Sociodemographic Correlates and Cessation Motivations of U.S. Adolescent E-Cigarette Use.
Conclusions . E-cigarette use is more common among certain adolescent subgroups than others and does not appear to be part of a cessation regimen among conventional cigarette smokers wishing to quit. More regulatory and prevention efforts are needed, especially for certain adolescent subpopulations. PMID: 24968185 [PubMed - as supplied by publisher] (Source: American Journal of Health Promotion : AJHP)
Section: bioprocessing and biological engineering gene fragment polymerization for increased yield of recombinant HIV fusion inhibitor enfuvirtide.
Authors: Gudipudi A, Bajji C, Kosana RR, Panati K, Lomada D, Arva Tatireddigari VR, Narala VR Abstract Fuzeon (Enfuvirtide, T20) is the first fusion inhibitor approved by the FDA of the USA for the treatment of HIV/AIDS in combination with other anti-retroviral drugs. Enfuvirtide is a synthetic peptide that blocks the entry of HIV into healthy host CD4 cells, which requires very high (90 mg twice daily) therapeutic doses. To increase the yield of Enfuvirtide, a gene polymerization strategy was introduced and recombinant T20 (rT20) was expressed in Escherichia coli as a five copy repeat polypeptide with a histidine-tag. The five copy rT20 was purified by Ni-affinity chromatography and cleaved to single rT20 units by cyanogen bromide. Finally, single rT20 units were purified by reve...
The Evolving Scenario of Non-AIDS-Defining Cancers: Challenges and Opportunities of Care.
CONCLUSION: Recent clinical studies have suggested that equivalent antineoplastic treatment is feasible and outcome can be similar in HIV-infected patients on HAART compared with uninfected patients for the treatment of HL and anal and lung cancers. However, patients with advanced HIV disease and/or aging-related comorbidities are likely to experience worse outcomes and have poorer tolerance of therapy compared with those with less advanced HIV disease. PMID: 24969164 [PubMed - as supplied by publisher] (Source: The Oncologist)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
HIV Did Not Stop Me From Having a Biological Child
On Monday, April 15, 2013, at 8:00 a.m., my life changed forever. My wife, Kasiah, and I welcomed our first child, a healthy girl named Finley Elizabeth Banks, into this world. She was perfect. But the journey to have a healthy, HIV-free biological child began many years before Finley&#8217;s birth. MoreFederal Appeals Court Strikes Down Utah's Gay Marriage Ban NBC NewsJessica N. Turner: Moms, Put on That Swimsuit Huffington PostShould the Cops Get to Look at Your Cellphone? NBC NewsParty's Over? GOP's Insurgents Take More Punches NBC NewsUruguay eliminates Italy; Did Suarez bite again? Sports IllustratedIn 1981, when I was two years old, I was diagnosed with Bilateral Wilms? tumors, a cancer of the kidneys, which had also spread to both of my lungs. The prognosis was grim; treatment was...
Fraud charges for AIDS researcher over fake data
Federal charges filed against scientist who admitted using false data to get millions in grant money (Source: Health News: CBSNews.com)
Kenya: 100,000 People Get Infected With HIV-Aids Yearly
[The Star]Close to 100 thousand people get infected yearly with HIV/AIDS. William Maina from the Health Ministry says even though there has been a decline in HIV/AIDS prevalence which is at 5.6%, some regions continue to record no changes in the fight against the disease, accounting for 30% of deaths in the country. (Source: AllAfrica News: HIV-Aids and STDs)
Africa: Civil Society Urges 'Full Expression of Demand' in Global Fund Concept Notes
[GFO]Three delegations from the Global Fund Board joined 11 international non-government organizations to encourage countries that are eligible to receive Global Fund support to develop concept notes that include the 'full expression of demand' for resources. (Source: AllAfrica News: HIV-Aids and STDs)
Kenya: Policy and Attitudes Hampering Fight Against HIV and Aids Amongst Sex Workers
[IPS]Nairobi -New HIV infections remain high among sex workers in Kenya. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
East Africa: East African Community to Tackle Transport Corridors in Second HIV Strategic Plan
[GFO]A broad cross-section of stakeholders from government and civil society met in Nairobi from 9-11 June as part of a country-level consultation to inform the development of regional priorities across the East African Community for its second strategic plan (2015-2020). (Source: AllAfrica News: HIV-Aids and STDs)
Africa: Aidspan Launches New Grant Performance Analysis Tool
[GFO]Users may now compare individual performance by country, region, disease or recipient -- over time or at a moment in time (Source: AllAfrica News: HIV-Aids and STDs)
Uganda: Flat Funding, Harsh Laws Could Hurt Uganda's Battle Against HIV
[IRIN]Kampala -Inadequate funding coupled with harsh laws targeting same sex unions could erode the gains so far made in the fight against HIV in Uganda, activists warn. (Source: AllAfrica News: HIV-Aids and STDs)
Steep drop in projected attendance at International AIDS Conference
Australian locale could cut participation in half (Source: ScienceNOW)
Angola: HIV Mother-to-Child Transmission Prevention Service Available in Caála
[ANGOP]Caála -Mother-to-child HIV transmission prevention service is available since early this month in the health centres of the communes of Calenga, Cuima and Catata, in the municipality Caála, central Huambo province. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Vaccine researcher charged with felony crimes for research fraud; may spend 20 years in prison over faked AIDS vaccine
(NaturalNews) Scientific fraud is so common in the vaccine industry, it's practically the default business model. The truth is that most vaccines don't work, so in order to make them appear to work, researchers routinely spike blood samples of vaccinated test subjects with antibodies... (Source: NaturalNews.com)
Aging with HIV and AIDS: A growing social issue
(St. Michael's Hospital) As the first people with HIV grow old, a new study from St. Michael's Hospital questions whether the health care system and other government policies are prepared to meet their complex medical and social needs. (Source: EurekAlert! - Social and Behavioral Science)
New technology to treat sepsis, a global killer
(Oregon State University) Engineers are developing a new technology that they believe could revolutionize the treatment and prevention of sepsis. This 'hidden killer' in the United States actually kills more people every year than AIDS, prostate cancer and breast cancer combined. (Source: EurekAlert! - Medicine and Health)
Avanti lipid tools: Connecting lipids, technology, and cell biology.
This article is part of a Special Issue entitled Tools to study lipid functions. PMID: 24954118 [PubMed - as supplied by publisher] (Source: Biochimica et Biophysica Acta)
Kaposi's sarcoma: a population?based cancer registry descriptive study of 57 consecutive cases diagnosed between 1977 and 2009
ConclusionKS, which used to be a rare illness, as it existed only in the classic form, has become more common since the appearance of HIV and, to a lesser extent, of immunosuppressive treatment. (Source: International Journal of Dermatology)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Host-directed therapy of tuberculosis based on interleukin-1 and type I interferon crosstalk
Nature advance online publication 25 June 2014. doi:10.1038/nature13489 Authors: Katrin D. Mayer-Barber, Bruno B. Andrade, Sandra D. Oland, Eduardo P. Amaral, Daniel L. Barber, Jacqueline Gonzales, Steven C. Derrick, Ruiru Shi, Nathella Pavan Kumar, Wang Wei, Xing Yuan, Guolong Zhang, Ying Cai, Subash Babu, Marta Catalfamo, Andres M. Salazar, Laura E. Via, Clifton E. Barry III & Alan Sher Tuberculosis remains second only to HIV/AIDS as the leading cause of mortality worldwide due to a single infectious agent. Despite chemotherapy, the global tuberculosis epidemic has intensified because of HIV co-infection, the lack of an effective vaccine and the emergence of multi-drug-resistant bacteria. Alternative host-directed strategies could be exploited to improve treatment efficacy and outco...
Tunisia: 'Tunisia to Host in 2015 Most Important Congress On Evolution Registered in Matters of Fight Against Aids' (sidibé)
[Tunis Afrique Presse]"For the first time, Tunisia will host in 2015 the most important congress on the evolution registered in matters of fight against AIDS", said, Friday, Michel Sidibé Under-Secretary-General of the United Nations and UNAIDS Executive Director, at the end of a talk with Caretaker President Moncef Marzouki. (Source: AllAfrica News: Health and Medicine)
Africa: African Women Celebrate Their Christian Ministry in a Time of HIV and Aids
[WCC]Women from churches across Africa have gathered in Kenya to focus on the achievements, challenges and opportunities of women's ministry in African churches over the past 30 years, as well as their responses to the HIV and AIDS pandemic. These women church leaders from the region are participating in an ecumenical conference from 19 to 24 June in Limuru. (Source: AllAfrica News: Health and Medicine)
Cure for HIV is a 'major scientific priority'
Huge advancements have taken place in HIV treatment and prevention over the past 10 years, but there is still no cure or vaccine. A new review shows that because of advancements in treatment, people with the virus are living longer. Overall, new infections have decreased from 3.3 million in 2002 to 2.3 million in 2012. Global AIDS-related deaths peaked at 2.3 million in 2005, decreasing to 1.6 million by 2012. (Source: ScienceDaily Headlines)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Kenya: TB and HIV Coinfection Rates Reduce By 39 Percent
[The Star]TB and HIV/AIDS co-infection rates have reduced by 39% since 2005. Health PS Fred Segor says the drop is as a result of funds allocated to TB that has seen over 1.2 million people diagnosed with TB access the drugs for free as well as get tested for HIV/AIDS. (Source: AllAfrica News: Health and Medicine)
Kenya: Elgeyo Hosts Forum On HIV
[The Star]The wife of Elgeyo Marakwet Governor Alex Tolgos, Joyce, has launched plans to ensure zero transmission of HIV/Aids. (Source: AllAfrica News: HIV-Aids and STDs)
Menthol cigs 'encourage teens to smoke more'
Conclusion This large Canadian survey has worryingly found that despite the dangers of smoking, 16% of teenagers aged between 14 and 18 are smoking, and 89% of them intend to continue. The number of cigarettes smoked was higher in teenagers who smoked menthol cigarettes. This included those who reported at least one menthol cigarette smoked in the past 30 days, so they may not have been exclusive smokers of menthol cigarettes. These findings reflect the widespread belief that menthol cigarettes are deemed to be a more attractive option for teenagers. However, the survey is reliant on self-reporting and is likely to be an underestimate of the number of cigarettes smoked. It is unclear why 27% of the students did not participate in the survey, or why the researchers only included 4,736 of ...
Liberia: Nurse Discloses Patient's HIV Status
[NEWS]The Lutheran Church in Liberia (LCL) HIV and AIDS Program has conducted an investigation into a reported stigma and discrimination against a woman living with HIV in Bong County. (Source: AllAfrica News: HIV-Aids and STDs)
Zimbabwe: HIV+ Vapostori Shun ARVs for Holy Water
[New Zimbabwe]AN official with a civil society group involved in HIV and Aids has hit out at religious organisations that are promoting "faith healing" at the expense of anti-retroviral medication. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Many ER patients test positive for HIV while in most infectious stage
Human immunodeficiency virus (HIV) screening for emergency patients at an institution with a large number of ethnic minority, underinsured and uninsured people reveals few are HIV positive, but of those who are, nearly one-quarter are in the acute phase and more than one-quarter have infections that have already advanced to acquired immune deficiency syndrome (AIDS). (Source: ScienceDaily Headlines)
Simulation Model for Transcervical Laryngeal Injection Providing Real-time Feedback.
CONCLUSION: This is the first study to describe a simulator for developing transcervical vocal fold injection skills. The model provides real-time tactile and auditory feedback that aids in skill acquisition. Otolaryngologists reported increased confidence with transcervical injection after using the simulator. PMID: 24963092 [PubMed - as supplied by publisher] (Source: The Annals of Otology, Rhinology, and Laryngology)
CT aids treatment decisions for stroke
Intravenous tissue plasminogen activator works better and is harmful to fewer (more) (Source: AuntMinnie.com Headlines)
Coca-Cola, partners boost ?Project Last Mile? (SLIDESHOW)
The Coca-Cola Co., the U.S. Agency for International Development, the Global Fund to Fight AIDS, Tuberculosis and Malaria, and the Bill & Melinda Gates Foundation will expand their ?Project Last Mile? program to include 10 African countries over the next five years. The public-private partnership -- currently focused on Tanzania and Ghana -- applies Atlanta-based Coca-Cola?s (NYSE: KO) logistic, supply chain, distribution and marketing expertise to help African governments maximize the ability? (Source: bizjournals.com Health Care:Hospitals headlines)
Zimbabwe: HIV Tests: Remember the Children
[The Herald]THE increase in HIV counselling and testing bodes well for Zimbabwe's commendable fight against HIV and Aids, but what about the children? (Source: AllAfrica News: Health and Medicine)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Nigeria: Day of African Child 2014 in Retrospect
[Independent]June 16th of every year is earmarked and dedicated to celebrate every African Child. In the midst of huge burden of preventable disease, disability and death, African child especially Nigerian needs more to desire in the area of good and affordable health delivery service. (Source: AllAfrica News: HIV-Aids and STDs)
Uganda: HIV+ Christian Couples Cheating
[Observer]If Uganda is losing ground in the campaign against HIV/Aids, it could be because priests and pastors are failing to impact on their flock. (Source: AllAfrica News: Health and Medicine)
Zimbabwe: Tertiary Institutions Top New HIV Infections
[The Herald]HIGHER and tertiary education institutions have the highest rate of new HIV infections, the National AIDS Council (NAC) has said. In an interview on the sidelines of a workshop to train HIV and Aids focal persons in tertiary institutions in Kwekwe last week, NAC youth co-ordinator Mrs Beauty Nyamwanza said most HIV infections started in tertiary institutions. (Source: AllAfrica News: Health and Medicine)
Tanzania: Foreign-Funded Aids Project Earmarked to Wind Up This Year
[Daily News]THE United States Agency for International Development (USAID)-funded programme under the Development Alternative Inc's project is set to wind up its operations in the country next December, after four years of efforts to improve the economic status of households affected by AIDS. (Source: AllAfrica News: Health and Medicine)
Advanced CT protocol aids treatment decisions for stroke
Intravenous tissue plasminogen activator works better and is harmful to fewer (more) (Source: AuntMinnie.com Headlines)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Zimbabwe: More People Taking HIV Tests
[The Herald]The number of Zimbabweans going for voluntary HIV testing and counselling has increased two-fold from about one million to over two million between 2012 and 2013, the National Aids Council has said. (Source: AllAfrica News: HIV-Aids and STDs)
Sexual Risk and Viral Suppression in HIV+ US Adults on ARTSexual Risk and Viral Suppression in HIV+ US Adults on ART
Is viral suppression among HIV-infected adults in the United States associated with decreased sexual risk behaviors? AIDS (Source: Medscape Today Headlines)
Four foods rich in essential magnesium
(NaturalNews) Magnesium is a vital macromineral that is needed for more than 300 biochemical reactions in the body. It regulates enzyme reactions, aids the production of ATP, helps the body transport ions across the cell membranes and much more. Indeed, all of the body's organs require... (Source: NaturalNews.com)
Cayenne pepper makes herbs up to 75% more effective, aids weight loss, offers pain relief, improves circulation and heals ulcers
(NaturalNews) Cayenne pepper, also known as capsicum, adds flavor to your food and has some impressive health benefits. Cayenne stimulates blood flow and can help burn body fat. It also fights inflammation and stimulates digestion, which helps break down food for better nutrient absorption... (Source: NaturalNews.com)
Tanzania: Shortage of TB, HIV Machines Hamper Treatment
[Daily News]UNAVAILABILITY and irregular supply of essential medicines and diagnostic facilities are impeding people suffering from tuberculosis, malaria and HIV/Aids from accessing and adhering to treatment. (Source: AllAfrica News: Health and Medicine)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
[Review] HIV and schistosomiasis co-infection in African children
HIV/AIDS and schistosomiasis both cause a substantial disease burden in sub-Saharan Africa and the two diseases often overlap in their epidemiological characteristics. Although disease-specific control interventions are continuing, potential synergies in the control efforts for these two diseases have not been investigated. With a focus on children with schistosomiasis, we assess the risk for increased HIV transmission, HIV progression, and impaired response to drugs when given alongside HIV interventions. (Source: The Lancet Infectious Diseases)
[Media Watch] Taking steps to end HIV
4 years ago, 21-year-old Joseph Kibler decided that he wanted to show people and especially teenagers that HIV/AIDS is still an issue in the USA, despite people with the disease living longer than ever before. Kibler's film-school thesis began life as a public service announcement about why people take part in the Los Angeles AIDS Walk, but ended up as a documentary film about Joseph, who was born with HIV, taking part in the 6 mile walk. (Source: The Lancet Infectious Diseases)
[Media Watch] Universal access to HIV care including antiretrovirals
The past decade has seen a momentous and unprecedented revolution in access to HIV care including effective combination antiretroviral treatment. 10 years ago the market for this expensive treatment was almost completely confined to people living with HIV in high-income countries. Since then, a transformation has happened, which has provided access to care to more than 10 million people living with HIV worldwide, most of whom live in middle-income and low-income countries. In AIDS Drugs for All: Social Movements and Market Transformations, Kapstein and Busby ask how this change happened, what were the mechanisms, was it inevitable, does it contain any negative consequences, and will it last? (Source: The Lancet Infectious Diseases)
[Newsdesk] Research brief
The ability of HIV to enter a latent state is a major barrier to finding a cure for HIV/AIDS. Researchers now report that compounds that induce the stochastic fluctuations (?noise?) in gene expression around the mean expression level that often drives cell-fate decisions could help to reactivate latent HIV. In a screen of bioactive small molecules, the researchers identified more than 80 compounds that modulated HIV gene-expression noise without changing mean expression. Notably, these noise-modulating compounds synergised with known transcriptional activators to reactivate HIV in latently infected human cells. (Source: The Lancet Infectious Diseases)
[Corrections] Corrections
Mfinanga SG, Kirenga BJ, Chanda DM, et al. Early versus delayed initiation of highly active antiretroviral therapy for HIV-positive adults with newly diagnosed pulmonary tuberculosis (TB-HAART): a prospective, international, randomized, placebo-controlled trial. Lancet Infect Dis 2014; 14: 563?71?In table 5 of this Article, for the CAMELIA trial, the median follow-up should have been 25 months, and the number of deaths or cases of AIDS per 100 person-years should have been 8·3 for the early ART group and 13·8 for the late ART group. (Source: The Lancet Infectious Diseases)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
[Editorial] A new chapter in HIV
In this issue of The Lancet Infectious Diseases, you will notice a large amount of HIV content in the journal. We have pooled this content from the many HIV/AIDS-related submissions that the journal received to mark the occasion of the 20th International AIDS Conference, AIDS 2014, in Melbourne this year, July 20?25. This content also heralds an exciting development in the Lancet journals' engagement with the HIV community, the launch of a new title: The Lancet HIV. (Source: The Lancet Infectious Diseases)
[Comment] HIV treatment strategies that can weather future challenges
Early initiation of antiretroviral therapy not only prevents AIDS and extends survival of people with HIV, but also significantly reduces new HIV infections. At the core of the treatment-as-prevention strategy is the goal of using safer, simpler, and better tolerated antiretroviral regimens to sustain suppression of viral replication and maintain an undetectable plasma viral load. The goal of treatment as prevention is to achieve immune reconstitution and disease-free survival; as the viral load becomes undetectable in biological fluids (eg, semen, vaginal fluids, blood) the risk of HIV transmission decreases by more than 95%. (Source: The Lancet Infectious Diseases)
Malawi: Journalists Urged to Contribute Towards the National Response to PLHIV
[Malawi News Agency]Lilongwe -Network of Journalists Living with HIV/AIDS (JONEHA) has urged the media houses in the country to share experiences in the implementation of HIV programme as a contribution towards the national response by People Living with HIV (PLHIV). (Source: AllAfrica News: HIV-Aids and STDs)
Diagnoses, prevalence, and state-based federal spending for HIV prevention and treatment in the United States, 2006-2009.
CONCLUSIONS: Our findings suggest that state-based federal resource allocation for HIV prevention and treatment may be better aligned with HIV diagnosis and prevalence rates than previously reported; however resource allocation for HIV prevention is less aligned than funding for HIV treatment signaling the need to reexamine state-based federal funding for HIV prevention. PMID: 24944562 [PubMed] (Source: AIDS Research and Therapy)
Receptor Conformation and Constitutive Activity in CCR5 Chemokine Receptor Function and HIV Infection.
Authors: Flanagan CA Abstract The CCR5 chemokine receptor mediates the effects of proinflammatory ?-chemokines that stimulate chemotaxis, activation, and proliferation of macrophages and T cells. CCR5 is also the major coreceptor that mediates HIV infection in combination with CD4. Chemokine agonists of CCR5 stimulate the activation of cellular calcium and protein kinase signaling pathways that depend on the activation of G?i and probably also G?q in some cells. Chemokines also stimulate the recruitment of ?-arrestin, which is required for clathrin-dependent receptor internalization and acts as a scaffold protein for the chemotaxis signaling complex that mobilizes the actin cytoskeleton. CCR5 is partially constitutively active for the activation of G?i, but the physiological s...<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Sexual risk behavior among people living with HIV and AIDS on antiretroviral therapy at the regional hospital of Sokode, Togo
Conclusion: There was a high prevalence of unsafe sex among PLWHA receiving ART at the hospital of Sokode. Factors associated with sexual risk behaviors were: low education level, non-adherence to ART, alcohol consumption before sex and the duration of ART. It is important to strengthen the implementation of secondary prevention strategies among this population group. (Source: BMC Public Health - Latest articles)
A web-based intervention trial for depressive symptoms and subjective well-being in patients with chronic HIV infection
(Source: AIDS Care)
Youth, violence and non-injection drug use: nexus of vulnerabilities among lesbian and bisexual sex workers
(Source: AIDS Care)
HIV seroprevalence and high-risk sexual behavior among female sex workers in Central Brazil
(Source: AIDS Care)
Sexual safety practices of massage parlor-based sex workers and their clients
(Source: AIDS Care)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
HIV testing in US emergency departments, outpatient ambulatory medical departments, and physician offices, 1992&#8211;2010
(Source: AIDS Care)
Impacts of four communication programs on HIV testing behavior in South Africa
(Source: AIDS Care)
Attrition of MSM with HIV/AIDS along the continuum of care from screening to CD4 testing in China
(Source: AIDS Care)
HCV, HBV, and HIV seroprevalence, coinfections, and related behaviors among male injection drug users in Arak, Iran
(Source: AIDS Care)
Incidence and associated factors of pulmonary tuberculosis in HIV-infected children after highly active antiretroviral therapy (HAART) in China: a retrospective study
(Source: AIDS Care)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
The impact of HIV on children's education in eastern Zimbabwe
(Source: AIDS Care)
HIV disclosure and its effect on treatment outcomes in perinatal HIV-infected Thai children
(Source: AIDS Care)
Patient satisfaction with HIV/AIDS care at private clinics in Dar es Salaam, Tanzania
(Source: AIDS Care)
The HIV basic care package: where is it available and who receives it? Findings from a mixed methods evaluation in Kenya and Uganda
(Source: AIDS Care)
Aspects of gay male couples' sexual agreements vary by their relationship length
(Source: AIDS Care)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Oregon patients with HIV infection who experience delayed diagnosis
(Source: AIDS Care)
Hepatitis C treatment eligibility among HIV&#8211;hepatitis C virus coinfected patients in Oregon: a population-based sample
(Source: AIDS Care)
Improving cervical cancer screening rates in an urban HIV clinic
(Source: AIDS Care)
If you build it will they come? Addressing social isolation within a technology-based HIV intervention for young black men who have sex with men
(Source: AIDS Care)
Healthcare provider intervention on smoking and quit attempts among HIV-positive versus HIV-negative MSM smokers in Chengdu, China
(Source: AIDS Care)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Blog Post » AIDS: A Cautionary Tale
There are many obstacles to controlling illnesses such as HIV/AIDS, even when effective treatment is available; Dr. Insel talks about what is needed to ensure that effective health care is delivered to those who need it. (Source: National Institute of Mental Health)
Joint modeling of longitudinal and survival data with missing and left?censored time?varying covariates
AbstractWe propose a joint model for longitudinal and survival data with time?varying covariates subject to detection limits and intermittent missingness at random. The model is motivated by data from the Multicenter AIDS Cohort Study (MACS), in which HIV+ subjects have viral load and CD4 cell count measured at repeated visits along with survival data. We model the longitudinal component using a normal linear mixed model, modeling the trajectory of CD4 cell count by regressing on viral load, and other covariates. The viral load data are subject to both left censoring because of detection limits (17%) and intermittent missingness (27%). The survival component of the joint model is a Cox model with time?dependent covariates for death because of AIDS. The longitudinal and survival models ...
HIV/AIDS status disclosure increases support, behavioural change and, HIV prevention in the long term: a case for an Urban Clinic, Kampala, Uganda
Conclusions: There is overwhelming support to individuals that disclose their HIV status, especially in the long term. Besides, gender appears to influence responses to HIV disclosure, highlighting the need for gender specific disclosure support strategies. (Source: BMC Health Services Research)
In vivo evaluation of self emulsifying drug delivery system for oral delivery of nevirapine
A. S. Chudasama, V. V. Patel, M. Nivsarkar, Kamala K. Vasu, C. J. ShishooIndian Journal of Pharmaceutical Sciences 2014 76(3):218-224Nevirapine is a highly lipophilic and water insoluble non-nucleoside reverse transcriptase inhibitor used for the treatment of HIV-1 infection. Lymphoid tissue constitutes the major reservoir of HIV virus and infected cells in HIV-infected patients. Self-emulsifying drug delivery system, using long chain triglycerides, is a popular carrier of drugs due to their ability to transport lipophilic drugs into the lymphatic circulation. However, HIV/AIDS patients experience a variety of functional and anatomical abnormalities in gastrointestinal tract that result in diarrhoea and nutrient malabsorption. Medium chain triglycerides are readily absorbed from the small ...
Reducing risky relationships: a multisite randomized trial of a prison-based intervention for reducing HIV sexual risk behaviors among women with a history of drug use
(Source: AIDS Care)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Role of individual's T-cell immunome in controlling HIV-1 progression.
In conclusion, in absence of bias due to viral strain diversity, it is the overall fitting of the HLA molecules capable of better binding HIV-1 proteins in determining the major role in the control of HIV-1 replication and progression to AIDS. This article is protected by copyright. All rights reserved. PMID: 24954875 [PubMed - as supplied by publisher] (Source: Immunology)
MMWR: Behavioral and Clinical Characteristics of Persons Receiving Medical Care for HIV Infection ? Medical Monitoring Project, United States, 2009
The Medical Monitoring Project (MMP) is an ongoing surveillance system that assesses behaviors and clinical characteristics of HIV-infected persons aged ?18 years who have received outpatient medical care. The findings in this report indicate that most adults living with HIV who received medical care in 2009 were taking antiretroviral therapy, had CD4+ T-lymphocyte and HIV viral load testing at regular intervals, and had health insurance or other coverage. However, some patients did not receive clinical services and treatment in accordance with guidelines. Some patients engaged in behaviors, such as unprotected sex, that increase the risk for transmitting HIV to sex partners, and some used noninjection or injection drugs or both. Local and state health departments and federal agencies ca...
Addressing the Growing Cancer Burden in the Wake of the AIDS Epidemic in Botswana: The BOTSOGO Collaborative Partnership.
Authors: Efstathiou JA, Bvochora-Nsingo M, Gierga DP, Alphonse Kayembe MK, Mmalane M, Russell AH, Paly JJ, Brown C, Musimar Z, Abramson JS, Bruce KA, Karumekayi T, Clayman R, Hodgeman R, Kasese J, Makufa R, Bigger E, Suneja G, Busse PM, Randall TC, Chabner BA, Dryden-Peterson S Abstract Botswana has experienced a dramatic increase in HIV-related malignancies over the past decade. The BOTSOGO collaboration sought to establish a sustainable partnership with the Botswana oncology community to improve cancer care. This collaboration is anchored by regular tumor boards and on-site visits that have resulted in the introduction of new approaches to treatment and perceived improvements in care, providing a model for partnership between academic oncology centers and high-burden countries wi...
Uptake of PrEP Can Be High, Demo Project ShowsUptake of PrEP Can Be High, Demo Project Shows
Gay and bisexual men who were offered HIV pre-exposure prophylaxis (PrEP) as part of a comprehensive prevention program had high levels of adherence to the regimen. Medscape Medical News (Source: Medscape Medical News Headlines)
Next-generation hearing aids get some iPhone cool
The first iPhone-compatible hearing aids allow music streaming and boast location-aware fine-tuning &ndash; one day everyone will want one (Source: New Scientist - Health)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Zimbabwe: HIV+ Zim Prisoners Take Botswana to Court
[Zimbabwe Independent]GABORONE High Court judge Justice Bengbame Sechele last week reserved judgement in a case in which two HIV-infected Zimbabwean prisoners took the government of Botswana to court challenging its policy of refusing anti-retroviral treatment to foreign inmates. (Source: AllAfrica News: HIV-Aids and STDs)
Mozambique: ARV Shortages Hit Mozambique's HIV Treatment Programme
[IPS]Maputo -Chronic shortages of antiretrovirals across Mozambique are endangering the health and the lives of tens of thousands of HIV positive people on treatment. (Source: AllAfrica News: HIV-Aids and STDs)
Kenya: Fight HIV, Says Obado's Wife
[The Star]Migori Governor Okoth Obado's wife Hellen has called on women to fight HIV-Aids. Hellen was speaking yesterday during the launch of a sensitisation programme on HIV-Aids prevention in Migori county. (Source: AllAfrica News: Health and Medicine)
Uganda: Uganda to Be HIV-Free By 2020 - Rugunda
[Observer]As regional campaigns for elimination of mother-to-child HIV/Aids transmission (EMTCT) peaked in West Nile last weekend, government said it would not settle for anything less than an HIV-free generation. (Source: AllAfrica News: Health and Medicine)
Nigeria: HIV/Aids - Ogun House Passes Anti-Stigmatisation Bill
[Leadership]The Ogun Assembly on Thursday passed a bill for an Act prohibiting all forms of stigmatisation and discrimination against persons living with HIV/AIDS in the state. (Source: AllAfrica News: Health and Medicine)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
[Report] HIV-1?induced AIDS in monkeys
Development of an AIDS-like animal disease model after serial passage of HIV-1 in pigtailed macaques is shown. Authors: Theodora Hatziioannou, Gregory Q. Del Prete, Brandon F. Keele, Jacob D. Estes, Matthew W. McNatt, Julia Bitzegeio, Alice Raymond, Anthony Rodriguez, Fabian Schmidt, C. Mac Trubey, Jeremy Smedley, Michael Piatak, Vineet N. KewalRamani, Jeffrey D. Lifson, Paul D. Bieniasz (Source: Science: Current Issue)
[HIV Pathogenesis] Adapting HIV-1 to infect monkeys, too
HIV-1 replicates well in humans but not in monkeys or mice. On the up side, this reduces the risk of cross-species transmissions, but it makes the study of HIV-1 and AIDS more difficult. ? [Read More] (Source: This Week in Science)
Behavioral and Clinical Characteristics of Persons Receiving Medical Care for HIV Infection - Medical Monitoring Project, United States, 2009.
Authors: Blair JM, Fagan JL, Frazier EL, Do A, Bradley H, Valverde EE, McNaghten A, Beer L, Zhang S, Huang P, Mattson CL, Freedman MS, Johnson CH, Sanders CC, Spruit-McGoff KE, Heffelfinger JD, Skarbinski J, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, CDC Abstract Problem: As of December 31, 2009, an estimated 864,748 persons were living with human immunodeficiency virus (HIV) infection in the 50 U.S. states, the District of Columbia, and six U.S.-dependent areas. Whereas HIV surveillance programs in the United States collect information about persons with a diagnosis of HIV infection, supplemental surveillance systems collect in-depth information about the behavioral and clinical characteristics of persons receiving outpatient medical care for HIV infect...
June 27 is National HIV Testing Day
According to the Centers for Disease Control and Prevention (CDC), about 50,000 people get infected with HIV each year in the United States. However, 1 in 6 people living with HIV don&rsquo;t know that they are infected. National HIV Testing Day is observed each year on June 27 to highlight the importance of HIV testing. CDC recommends that everyone between the ages of 13 and 64 get tested for HIV at least once as part of their routine health care. Regardless of age, people at high risk of HIV should get tested more often. Visit the AIDSinfo National HIV Testing Day webpage [en espa&ntilde;ol] to learn more about HIV testing and to find a testing center near you. (Source: AIDSinfo At-a-Glance: Offering Information on HIV/AIDS Treatment, Prevention, and Research, A Service of the U.S. Dep...
Changes to the Complera (Emtricitabine/Rilpivirine/Tenofovir Disoproxil Fumarate) Labeling
&quot;On June 5, 2014, FDA approved changes to the Complera (emtricitabine/rilpivirine/tenofovir disoproxil fumarate) fixed-dose combination tablet labeling to include rilpivirine dose adjustment information when Complera is coadministered with rifabutin.&quot; The updated labeling for Complera is&nbsp;available at the&nbsp;FDA website. More information is available: FDA: Press release AIDSinfo: Patient fact sheet on Complera (Source: AIDSinfo At-a-Glance: Offering Information on HIV/AIDS Treatment, Prevention, and Research, A Service of the U.S. Department of Health and Human Services (DHHS))<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
New Pediatric Dosage Form and Label Changes for Reyataz (Atazanavir)
&quot;On June 2, 2014, FDA approved a new dosage form, Reyataz (atazanavir) oral powder for use in combination with other antiretroviral agents for the treatment of HIV-1, in patients over 3 months of age and between 10 kg to &lt; 25 kg. The first part of this announcement summarizes the changes relevant to the oral formulation and use in pediatric patients. The second part summarizes other general changes to the label.&quot; The updated labeling for atazanavir is&nbsp;available at the&nbsp;FDA website. More information is available: FDA: Press release AIDSinfo: Patient fact sheet on atazanavir (Source: AIDSinfo At-a-Glance: Offering Information on HIV/AIDS Treatment, Prevention, and Research, A Service of the U.S. Department of Health and Human Services (DHHS))
Community-based implementation and effectiveness in a randomized trial of a risk reduction intervention for HIV-serodiscordant couples: study protocol
This study will produce important information regarding the value of the Eban II program and a theory-guided implementation process and tools designed for use in implementing Eban II and other evidence-based programs in demographically diverse, resource-constrained treatment settings.Trial registration: NCT00644163 (Source: BioMed Central)
Health and social support services to HIV/AIDS infected individuals in Tanzania: employees and employers perceptions
Conclusions: HIV/AIDS infected employees named treatment and nutritional support, and soft loans and reduced workload respectively, as the most important health and social supports they needed from their employers. This study provides baseline information for further studies on provision of health and social support services by employers to HIV/AIDS infected employees in the context of a developing economy like Tanzania. (Source: BMC Public Health - Latest articles)
Angola: Health Ministry Boosts Operational Strategies to Reducing STDs/HIV
[ANGOP]Luanda -The reinforcement of sensitizing actions aimed to reduce Sexual Transmitted Diseases (STDs) and HIV are some strategies of the Ministry of Health in order to reduce these illnesses, said on Thursday, in Luanda the deputy general director of National Institute of Fighting against Aids (Inls), Maria Lúcia Furtado. (Source: AllAfrica News: HIV-Aids and STDs)
Molecular Epidemiology of HIV Type 1 Infection in Kazakhstan: CRF02_AG Prevalence Is Increasing in the Southeastern Provinces
AIDS Research and Human Retroviruses , Vol. 0, No. 0. (Source: AIDS Research and Human Retroviruses)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
VIDEO: Meet the author: Norman Fowler
Health campaigner Norman Fowler talks to Nick Higham about his new book, Aids: Don't Die of Prejudice. (Source: BBC News | Health | UK Edition)
New monkey model for AIDS offers promise for medical research
HIV-1, the virus responsible for most cases of AIDS, is a very selective virus and does not readily infect species other than its usual hosts ? humans and chimpanzees ? making the search for effective treatments and vaccines for AIDS that much more difficult. In new scientific work, researchers have coaxed a slightly modified form of the HIV-1 virus to not only infect pigtailed macaques, a species of monkey, but to cause full blown AIDS in the primates, a first. (Source: ScienceDaily Headlines)
Mechanism discovered for attaching an 'on' switch that helps cells accessorize proteins
Scientists have discovered how an important ?on? switch is attached to the machinery that cells rely on to adapt thousands of proteins to meet changing conditions. The switch is a small protein called NEDD8. Problems with NEDD8 have been associated with several cancers, developmental disorders and infectivity of the human immunodeficiency virus (HIV), which causes AIDS. (Source: ScienceDaily Headlines)
New monkey model for AIDS offers promise for medical research
Rockefeller University researchers announce that they have coaxed a slightly modified form of the HIV-1 virus to not only infect pigtailed macaques but to cause full blown AIDS in the primates, an accomplishment that could accelerate the search for new AIDS treatments or vaccines. More &#187; (Source: The Rockefeller University Newswire)
Nicotine replacement products: poisoning in children -
Nicotine is widely used in smoking cessation aids. They are marketed in many forms, including: chewing gum, sublingual tablets, lozenges, transdermal patches, cartridges for oral inhalation, and mouth spray. French poison control and toxico-vigilance centr... (Source: SafetyLit: All (Unduplicated))<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Malawi: Stakeholders Asked to Include Gender Perspectives in HIV and Aids Programs
[Malawi News Agency]Mwanza -There is need to integrate gender issues in all HIV and AIDS programs so that women who are more susceptible to contracting HIV are protected and prevented just like their male counterparts. (Source: AllAfrica News: Health and Medicine)
Zimbabwe: Stepping Up the HIV Response
[The Herald]The failure of various interventions to tackle the HIV/Aids pandemic may have left some people despairing. (Source: AllAfrica News: HIV-Aids and STDs)
ARV Shortages Hit Mozambique?s HIV Treatment Programme
Chronic shortages of antiretroviral drugs endanger the lives of hundreds of thousands of HIV positive Mozambicans. Courtesy: Amos ZacariasBy Amos ZacariasMAPUTO, Jun 19 2014 (IPS) Chronic shortages of antiretrovirals across Mozambique are endangering the health and the lives of tens of thousands of HIV positive people on treatment. Some 454,000 people are on antiretroviral (ARV) treatment, or just under one-third of the 1.6 million Mozambicans living with HIV in 2013, according to government figures. ?Our patients complain they are not receiving the complete dosage of medicines,? says Judite de Jesus Mutote, president of Hi Xikanwe (?we are together,? in the local Shangaan language), a group that assists people on ARV treatment in Maputo. For ARVs to be effective, the pills must be...
Kenya: Tunai's Wife Steps Up Fight Against HIV-Aids
[The Star]Health practitioners and other stakeholders have been asked to step up the fight against HIV-Aids. (Source: AllAfrica News: HIV-Aids and STDs)
South Africa: Opinion - the Silver Bullet of Indicators?
[Health-e]The Treatment Action Campaign's Marcus Low writes why HIV viral load testing may be the most important HIV indicator. Now, if we could only monitor it. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Risk of cancer among HIV-infected individuals compared to the background population: impact of smoking and HIV
Conclusion:The risk of cancer is increased in HIV patients compared to the background population. In absence of smoking, the increase in risk is confined to cancers related to viral infections, whereas the risk of other cancers is not elevated and does not seem to be associated with immune deficiency. (Source: AIDS)
New monkey model for AIDS offers promise for medical research
(Rockefeller University) Rockefeller University researchers announce that they have coaxed a slightly modified form of the HIV-1 virus to not only infect pigtailed macaques but to cause full blown AIDS in the primates, an accomplishment that could accelerate the search for new AIDS treatments or vaccines. (Source: EurekAlert! - Biology)
Creating an advance-care-planning decision aid for high-risk surgery: a qualitative study
Conclusions: Stakeholders supported incorporating advance care planning in high-risk surgical settings and endorsed the appropriateness of using decision aids to do so. Findings will inform the next stages of developing the first advance care planning decision aid for high-risk surgery patients. (Source: BMC Palliative Care - Latest articles)
Entry and re?entry into informal care?giving over a 3?year prospective study among older people in Nairobi slums, Kenya
Abstract This paper analyses data from a 3?year prospective study to understand the factors associated with becoming a caregiver to a person with a chronic illness and examines the dynamics among caregivers over time. A total of 1485 participants were drawn from a study conducted in the slums of Nairobi, Kenya. Two waves of data collected in 2006 for the baseline and a follow?up in 2009 were used. Information on the demographic, self?reported health and socioeconomic characteristics such as education, sources of livelihood and employment status was used. Age was a significant factor in becoming a caregiver, but there were no significant differences by gender or marital status. New caregivers and those with more than one care?giving episode had a higher socioeconomic position than n...
An HIV Epidemic Model Based on Viral Load Dynamics: Value in Assessing Empirical Trends in HIV Virulence and Community Viral Load
by Joshua T. Herbeck, John E. Mittler, Geoffrey S. Gottlieb, James I. Mullins Trends in HIV virulence have been monitored since the start of the AIDS pandemic, as studying HIV virulence informs our understanding of HIV epidemiology and pathogenesis. Here, we model changes in HIV virulence as a strictly evolutionary process, using set point viral load (SPVL) as a proxy, to make inferences about empirical SPVL trends from longitudinal HIV cohorts. We develop an agent-based epidemic model based on HIV viral load dynamics. The model contains functions for viral load and transmission, SPVL and disease progression, viral load trajectories in multiple stages of infection, and the heritability of SPVL across transmissions. We find that HIV virulence evolves to an intermediate level that balances ...<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
A role of arachidonic acid in the regulation of nitric oxide synthase isoforms by HIV gp120 protein in astroglial cells.
Authors: Persichini T, Mastrantonio R, Matto SD, Palomba L, Cantoni O, Colasanti M Abstract HIV-associated neurocognitive disorders (HAND) is a common cognitive impairment in AIDS which affects 15 to 50% of adults infected with human immunodeficiency virus (HIV). Excessive amount of nitric oxide (NO), as produced by inducible NO synthase (iNOS) upon exposure of activated microglia and astrocytes to cytokines and/or viral proteins (e.g., HIV tat and gp120), is assumed to contribute to neuronal abnormalities in HAND. Evidence exists supporting the notion that iNOS induction takes place after an early decline in physiological NO levels (i.e., NO released by constitutive NOS, cNOS). Here, we demonstrate that HIV-1 gp120 is able to inhibit nNOS through a cytosolic phospholipase A2 (cPLA...
The Challenges of Implementing HIV Preexposure ProphylaxisThe Challenges of Implementing HIV Preexposure Prophylaxis
Dr. Paul Sax considers the challenges facing physicians charged with implementing the CDC's recent guidelines on HIV pre-exposure prophylaxis. Medscape HIV/AIDS (Source: Medscape Pharmacist Headlines)
Malawi: Community Radios Form HIV and Aids Workplace Policy
[Malawi News Agency]Mzuzu -The Community Radios in the Northern Region have formed an HIV and AIDS workplace policy aiming at reducing the negative impact on its social and economic activities. (Source: AllAfrica News: Health and Medicine)
Kenya: HIV Project Launched
[The Star]The National Network of Persons Living with HIV (NEPHAK) in collaboration with the Machakos County Government has rolled out a campaign to fight transmission of HIV/AIDs from Mother to Child. (Source: AllAfrica News: Health and Medicine)
Kenya: Nyandarua Seeks to Pass HIV Fund Law
[The Star]PEOPLE living with HIV in Nyandarua county will access a revolving fund to enable them pay for their medical care if the county assembly passes a bill into law. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Tanzania: Dar HIV Transmission Drops By 2.4 Percent
[Daily News]HIV/AIDS transmission has decreased by 2.4 per cent in Dar es Salaam Region, according to the National Bureau of Statistics. (Source: AllAfrica News: Health and Medicine)
Kenya: 5,000 Targeted in Tharaka HIV Drive
[The Star]MORE than 5,000 people are targeted in a HIV-Aids testing and treatment campaign in Tharaka Nithi county. (Source: AllAfrica News: HIV-Aids and STDs)
Nigeria: Military Records Declining HIV/Aids Prevalence - Obanikoro
[Independent]The Minister of State for Defence, Sen. Musliu Obanikoro, on Tuesday said the military recorded a decline in HIV and AIDS prevalence because of the efforts of the Federal Government. (Source: AllAfrica News: Health and Medicine)
Abscess resulting from Mycobacterium kansasii in the left thigh of AIDS patient
A case of abscess resulting from Mycobacterium kansasii, in the left thigh of a 53-year-old woman infected with the Human Immunodeficiency virus, is reported. Curiously, there was no pulmonary or systemic involvement as is usual with these Mycobacterium infections. The patient had CD4 T lymphocyte count of 257 cells/µL and a viral load of 60,154 copies. Despite presenting a relatively preserved immunity, the patient also presented Criptococcic meningoencephalitis and Esophageal candidiasis. The patient responded satisfactorily to treatment for infections and after 51 days was discharged. (Source: Anais Brasileiros de Dermatologia)
Children's psychosocial wellbeing in the context of HIV/AIDS and poverty: a comparative investigation of orphaned and non-orphaned children living in South Africa
Conclusions: The results muster additional evidence for moving beyond narrow definitions of vulnerability associated exclusively with orphanhood to consider the multitude of material, social and relational factors affecting the psycho-social well-being of children in general who are living in circumstances of poverty and HIV and AIDS. (Source: BMC Public Health - Latest articles)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Characteristics and coinfection with syphilis in newly HIV?infected patients at the University Hospital Dresden 1987?2012
ConclusionsOur findings suggest a causative relationship between recently rising incidences of syphilis and HIV infection in MSM. Early diagnosis of syphilis may promote earlier diagnosis of HIV infection; therefore, HIV prevention measures should also include other sexually transmitted infections. (Source: JDDG)
Antiretroviral-Related Alopecia in HIV-Infected Patients: A Review of the Literature.
CONCLUSIONS: In antiretroviral-induced alopecia, discontinuation of the suspected agent is the optimal management, and hair regrowth should occur within 1 to 3 months. Management may also include replacing the offending medication with an antiretroviral less likely to cause hair loss. It is essential to rule out other causes of alopecia with a complete patient history, including characterization of the hair loss and assessment of the patient's medical history, medication use, and family history of alopecia. PMID: 24944240 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy)
Thrombolysis Aids PE Survival, but Ups Bleeding Risk (CME/CE)
(MedPage Today) -- Thrombolytic therapy nearly halved mortality in patients with pulmonary embolism (PE), but at the cost of a higher risk of major bleeding, especially in the elderly, a meta-analysis found. (Source: MedPage Today Cardiovascular)
Arcadia Biosciences safflower oil product boosts omega-6 fatty acid
Davis-based Arcadia Biosciences Inc. is launching its product Sonova Ultra GLA Safflower Oil, which contains 55 percent of the omega-6 fatty acid that benefits skin health, weight management and women?s hormonal balance. Arcadia doesn?t sell it retail; rather it supplies the makers of supplements, energy bars and dietary aids. The primary traditional sources of omega-6 fatty acid are evening primrose or borage (starflower), both of which are difficult to cultivate. Arcadia genetically modified? (Source: bizjournals.com Health Care:Hospitals headlines)
An Integrative Review of Guidelines for Anal Cancer Screening in HIV-Infected Persons
AIDS Patient Care and STDs , Vol. 0, No. 0. (Source: AIDS Patient Care and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Mid-ATR-FTIR Spectroscopic Profiling of HIV/AIDS Sera for Novel Systems Diagnostics in Global Health
OMICS: A Journal of Integrative Biology , Vol. 0, No. 0. (Source: OMICS: A Journal of Integrative Biology)
Working to Break the Chain: Fighting HIV/AIDS in Arua, Uganda
Doctors Without Borders/Médecins Sans Frontières (MSF) began an HIV/AIDS clinic at Arua Hospital in the West Nile region of northern Uganda in 2001. Today, MSF provides antiretroviral (ARV) treatment to more than 3,000 people living with HIV/AIDS here. (Source: MSF News)
LGBT people's knowledge of and preparedness to discuss end?of?life care planning options
Abstract Despite the devastating impact of HIV/AIDS, end?of?life care planning among lesbian, gay, bisexual and transgender (LGBT) communities is relatively under?researched, especially in Australia. This paper reports findings of a survey of 305 LGBT people living in New South Wales, which examined their knowledge of and attitudes towards end?of?life care. The focus of this paper is their preparedness to discuss with healthcare providers any end?of?life care plans. The results highlight that while the majority of respondents were aware of three of the four key end?of?life care planning options available in New South Wales ? enduring powers of attorney, enduring guardians and person responsible (only a minority had heard of advance healthcare directives) ? a much smal...
Botswana: HIV Still Nation's Biggest Challenge
[Government of Botswana]HIV infection is still the biggest challenge facing the country, says coordinator of the National AIDS Coordinating Agency (NACA), Ms Grace Muzila. Briefing the media yesterday, June 16, about the recent Botswana AIDS Impact Survey (BAIS) IV, she said the national HIV prevalence rate was estimated at 18.5% among people aged 18 months and above. (Source: AllAfrica News: HIV-Aids and STDs)
Taking It One Day at a Time: African American Women Aging with HIV and Co-Morbidities
AIDS Patient Care and STDs , Vol. 0, No. 0. (Source: AIDS Patient Care and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Zambia: HIV/Aids Testing 'Scaring Away' Pregnant Women
[Times of Zambia]LIVINGSTONE District medical officer Cliff Hara has observed that most pregnant women in the district have been avoiding antenatal services because of compulsory HIV/AIDS testing for the women and their spouses. (Source: AllAfrica News: HIV-Aids and STDs)
Guava aids the body and the brain
(NaturalNews) Guavas are native to South America, Mexico and other parts of North America. They are cultivated in the tropics and subtropics of Africa, the Caribbean and parts of Asia, Hawaii, New Zealand, Australia and Spain. There are different species of guava, but the most commonly... (Source: NaturalNews.com)
Zimbabwe: HIV+ Ex-Employee Sues Hospital
[The Herald]AN HIV positive woman is suing her former employer, St Anne's Hospital, for $30 000 after she was allegedly forced to disclose her status before being arbitrarily fired. (Source: AllAfrica News: HIV-Aids and STDs)
Uganda: Opposition Against Uganda HIV Bill
[EA Business]Kampala -Uganda, The Uganda AIDS Commission has asked President Yoweri Museveni not to assent the recently passed HIV/AIDS Control Bill 2010 in its current form. (Source: AllAfrica News: Health and Medicine)
Thinking Outside the Heart: Use of Engineered Cardiac Tissue for the Treatment of Chronic Deep Venous Insufficiency
This article considers the use of autologous stem cell-derived cardiomyocytes as a novel means to aid venous return. The approach consists of creating external cuffs of engineered heart tissue around vein segments with incompetent or poorly competent valves. The engineered heart tissue cuff prevents distention of the impaired vein segments and aids unidirectional flow by its rhythmic contractions. There appear to be no fundamental limitations to this approach as feasibility of all of the individual components has already been shown. Here, we underline the clinical need for novel ways to treat chronic deep venous insufficiency, review previous research that enabled this approach, consider potential designs of engineered heart tissue cuffs, and outline its advantages and future challenges. (...<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Source apportionment of PAHs [Physical Sciences]
We thank Ahad et al. (1) for expanding on our recent study (2) by providing additional information that aids in explaining the missing emissions of polycyclic aromatic hydrocarbons (PAHs) in the Athabasca oil sands region (AOSR). They argue that evaporative releases from tailings ponds are likely not a major source... (Source: Proceedings of the National Academy of Sciences)
Does temporal preparation facilitate visual processing in a selective manner? Evidence from attentional capture.
Authors: Seibold VC, Rolke B Abstract The present study addressed the question of whether temporal preparation influences perceptual stimulus processing in a selective manner. In three visual search experiments, we examined whether temporal preparation aids spatial selection and thus reduces distraction caused by the onset of a task-irrelevant item. In each trial, participants had to detect a target amongst five non-targets and report a basic feature of the target. In some trials, an additional task-irrelevant singleton item (abrupt onset) appeared on the screen which distracted attention away from the target. To manipulate the degree of distraction, we varied the spatial distance and the stimulus-onset asynchrony between target and singleton. Temporal preparation for the target va...
Malawi: Empower Sex Workers to Demand Safe Sex - Badilika Foundation
[Malawi News Agency]Blantyre -Malawi will not win the fight against HIV and AIDS unless sex workers are empowered to demand safe sex as one way of HIV reducing transmission, says the Badilika Foundation. (Source: AllAfrica News: Health and Medicine)
Kenya: 3000 Living With HIV in Baringo
[The Star]About 3,000 people are living with HIV-Aids in Baringo county, according to a survey by Baringo County AIDS Control Council. (Source: AllAfrica News: HIV-Aids and STDs)
Tanzania: Minister Calls for Use of Local Resources to Fight HIV/Aids
[Daily News]Arusha -THE Minister for Tourism and Natural Resources, Mr Lazaro Nyalandu, has called for use of local resources to effectively fight against HIV/AIDS instead of depending on foreign funding. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Zambia: South Records 40 Percent New HIV Infections
[Times of Zambia]GOVERNMENT has attributed the major challenge to the HIV/AIDS response in Southern Province to the high rates of new infections among the young population aged between 15 and 24 years. (Source: AllAfrica News: HIV-Aids and STDs)
Malawi: Tilipo Reduces Teachers' Mortality Rate in Mangochi
[Malawi News Agency]Mangochi -School and HIV/Aids Coordinator for Mangochi District Education Office, Noel Nzunga has said since Teachers Living Positively with the virus (Tilipo) was introduced in 2007 annual mortality rate among teachers has been reduced drastically. (Source: AllAfrica News: HIV-Aids and STDs)
Malawi: Migration to South Africa Fueling HIV/Aids Spread in Mzimba
[Malawi News Agency]Mzimba -Every Child, a non-governmental organisation has asked Malawi Government to devise measures of controlling migration of its citizens to South Africa (SA) in search for jobs, saying the practice has become a major catalyst for spread of HIV/AIDS in Mzimba District. (Source: AllAfrica News: HIV-Aids and STDs)
Advancing the application of systems thinking in health: why cure crowds out prevention
Conclusions: We have created an artificial system as a laboratory to gain insights about the trade-offs between curative and preventive health allocations, and the effect of indicative policy interventions. The underlying dynamics of this artificial system resemble features of modern health systems where a self-perpetuating industry has grown up around disease-specific curative programs like HIV/AIDS or malaria. The model shows how the growth of curative care services can crowd both fiscal and policy space for the practice of population level prevention work, requiring dramatic interventions to overcome these trends. (Source: Health Research Policy and Systems)
A Comprehensive Approach to Risk Reduction for Asian and Pacific Islander American Women With HIV/AIDS
As HIV incidence rises globally, Asian and Pacific Islander communities are increasingly affected. While often overlooked, Asian and Pacific Islander American women have shown the greatest percentage increase in HIV diagnosis rates. The development of a multilevel and multistrategy approach to HIV/AIDS education, prevention, and treatment among Asian and Pacific Islander females requires health care providers to identify personal and cultural barriers to prevention and treatment and implement culturally sensitive and specific measures. The purpose of this article is to illuminate barriers to HIV-related prevention, treatment, and care among Asian and Pacific Islander American females and provide practical application-based suggestions for providers, which may enhance Asian and Pacific Isla...<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Central Nervous System Penetration and Effectiveness of Darunavir/Ritonavir Monotherapy.
Authors: Pérez Valero I, Gonzalez-Baeza A, Montes Ramirez ML Abstract Darunavir/ritonavir monotherapy is an experimental switching strategy for virologically suppressed patients without protease inhibitor resistance to avoid nucleos(t)ide-related toxicities. This therapy maintains virological suppression in most patients, but at slightly lower rates than standard therapy that includes two nucleos(t)ides. Patients experiencing virological failure are generally re-suppressed without emergence of resistance with the resumption of two nucleos(t)ides. Reports of cerebrospinal fluid viral escape has been observed in patients receiving protease inhibitor monotherapy, and concerns exist regarding the capacity of protease inhibitor monotherapy to control HIV infection in the brain and to p...
A rapid RT-PCR assay for the detection of HIV-1 in human plasma specimens.
CONCLUSIONS: We developed a comprehensive, easy to use assay for the detection of HIV-1 in human plasma. Our assay combines a rapid and cost-effective method for molecular diagnostics with the versatility necessary for widespread laboratory use. These performance characteristics make this HIV-1 detection assay highly suitable for use in a clinical laboratory. PMID: 24945443 [PubMed - as supplied by publisher] (Source: Experimental and Molecular Pathology)
Spatial design of hearing AIDS incorporating multiple vents.
Authors: Stevenson D, Searchfield G, Xu X Abstract The main aim of this study was to investigate the shape variation in the human ear canal and the effects of venting on the spatial design of hearing aids. The second aim was to determine the design feasibility of a multiple venting hearing aid and assess the flexibility of design provided. A statistical shape model based on principal component analysis was created from a dataset of 60 left and 49 right ears. The modal variations of these models were then examined to determine the narrowest portion of the ear canal likely to limit effective venting. Finally, 3D models of two hearing aid shells, one with multiple 0.4-mm vents and the other with a single large 3-mm vent were created. Results showed that more than 50% of the shape vari...
Quitgate Offers Quit Support and Huge Discounts on Stop Smoking Aids...
As a one-stop smoking cessation platform, Quitgate.com offers quit smoking help, stop smoking aids and social support treatments that increase the chances of smoking cessation as cited by the Centers...(PRWeb June 14, 2014)Read the full story at http://www.prweb.com/releases/quit-smoking/help/prweb11937287.htm (Source: PRWeb: Medical Pharmaceuticals)
Validation of the self-reported hearing questions in the Irish Longitudinal Study on Ageing against the Whispered Voice Test
Conclusions: We showed that this validity check was useful to select the questions that most effectively assess hearing deficits and provided crucial information for the subsequent waves. We argue that longitudinal studies using self-reports of sensory efficacy would benefit from a similar check. (Source: BMC Research Notes)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Dynamic analysis of oral Candida carriage, distribution, and antifungal susceptibility in HIV?infected patients during the first year of highly active antiretroviral therapy in Guangxi, China
ConclusionsThe Candida load decreased with increased CD4+ T cell counts, and C. albicans was still the prevailing species. Further, a trend toward more frequent in vitro resistance to fluconazole and itraconazole was observed. Our results provide reference for treatment and prevention of oral candidiasis among this population. (Source: Journal of Oral Pathology and Medicine)
In Developing World, Pollution Kills More Than Disease
Air and chemical pollution are growing rapidly in the developing world with dire consequences for health, says Richard Fuller, president of the Pure Earth/Blacksmith Institute. Credit: BigstockBy Stephen LeahyUXBRIDGE, Canada, Jun 13 2014 (IPS) Pollution, not disease, is the biggest killer in the developing world, taking the lives of more than 8.4 million people each year, a new analysis shows. That?s almost three times the deaths caused by malaria and fourteen times those caused by HIV/AIDs. However, pollution receives a fraction of the interest from the global community. ?Toxic sites along with air and water pollution impose a tremendous burden on the health systems of developing countries,? said Richard Fuller, president of the Pure Earth/Blacksmith Institute, which prepared the a...
HIV-Positive Men's Experiences with Integrated Family Planning and HIV Services in Western Kenya: Integration Fosters Male Involvement
AIDS Patient Care and STDs , Vol. 0, No. 0. (Source: AIDS Patient Care and STDs)
J&J Links Up With GSK-Led Group on 2-Drug HIV TabletJ&J Links Up With GSK-Led Group on 2-Drug HIV Tablet
Johnson & Johnson has linked up with ViiV Healthcare - a specialist HIV company majority-owned by GlaxoSmithKline - to develop a new AIDS medicine combining two drugs in a single tablet. Reuters Health Information (Source: Medscape Medical News Headlines)
The teaching of writing and the development of people with intellectual disabilities
This article proposes a theoretical reflection on the development of children with intellectual disabilities, regarding the importance and necessity of the process of learning the written language, from a historical-cultural point of view. For this approach, the course of development of a child disabled or not will occur according to cultural and social conditions experimented by him or her. Therefore, concerning the child with intellectual disabilities, his cultural condition, in dynamic relationship with the obstacles placed in its special condition, will be the source of his development. If the development of higher psychological functions is realized through the use of tools and if the people with intellectual disabilities present an inability to use these tools, there will be the need...<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
A relação orientadora-orientanda no primeiro encontro com a pesquisa
This article proposes a theoretical reflection on the development of children with intellectual disabilities, regarding the importance and necessity of the process of learning the written language, from a historical-cultural point of view. For this approach, the course of development of a child disabled or not will occur according to cultural and social conditions experimented by him or her. Therefore, concerning the child with intellectual disabilities, his cultural condition, in dynamic relationship with the obstacles placed in its special condition, will be the source of his development. If the development of higher psychological functions is realized through the use of tools and if the people with intellectual disabilities present an inability to use these tools, there will be the need...
A psicologia positiva como fomentadora do bem-estar e da felicidade
This article proposes a theoretical reflection on the development of children with intellectual disabilities, regarding the importance and necessity of the process of learning the written language, from a historical-cultural point of view. For this approach, the course of development of a child disabled or not will occur according to cultural and social conditions experimented by him or her. Therefore, concerning the child with intellectual disabilities, his cultural condition, in dynamic relationship with the obstacles placed in its special condition, will be the source of his development. If the development of higher psychological functions is realized through the use of tools and if the people with intellectual disabilities present an inability to use these tools, there will be the need...
"Saúde para Doença" ou patologização da saúde?
This article proposes a theoretical reflection on the development of children with intellectual disabilities, regarding the importance and necessity of the process of learning the written language, from a historical-cultural point of view. For this approach, the course of development of a child disabled or not will occur according to cultural and social conditions experimented by him or her. Therefore, concerning the child with intellectual disabilities, his cultural condition, in dynamic relationship with the obstacles placed in its special condition, will be the source of his development. If the development of higher psychological functions is realized through the use of tools and if the people with intellectual disabilities present an inability to use these tools, there will be the need...
Entre o labor acadêmico e a candura do engajamento: o higienismo por Boarini
This article proposes a theoretical reflection on the development of children with intellectual disabilities, regarding the importance and necessity of the process of learning the written language, from a historical-cultural point of view. For this approach, the course of development of a child disabled or not will occur according to cultural and social conditions experimented by him or her. Therefore, concerning the child with intellectual disabilities, his cultural condition, in dynamic relationship with the obstacles placed in its special condition, will be the source of his development. If the development of higher psychological functions is realized through the use of tools and if the people with intellectual disabilities present an inability to use these tools, there will be the need...
Virtual Guide On Ocular Self-Examination To Support The Self-Care Practice For People With HIV/AIDS
Objetivou-se descrever processo de desenvolvimento da cartilha virtual sobre autoexame ocular para pessoas com HIV/aids. A proposta metodológica seguiu as cinco etapas preconizadas por Falkembach: análise e planejamento, modelagem, implementação, avaliação e distribuição. A adequação da versão impressa para virtual requereu a construção de um vídeo tutorial, agregação de fotos ilustrativas para visualização de possíveis alterações oculares e ferramenta de interatividade com demonstração do resultado do exame ao usuário. Na avaliação inicial do material, foram diagnosticadas falhas no layout. Assim, comandos foram recolocados, unificados, dispostos em local de fácil visualização e foi feita a adequação da linguagem. Considera-se possível promover aproximaçã...<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Africa: New Aidspan Paper Explores the Role of the Local Fund Agent (lFA)
[GFO]Evolving responsibilities include risk management, accountability and effective oversight of grant implementation at country level (Source: AllAfrica News: HIV-Aids and STDs)
South Africa: Opinion - Helping to Fix the System
[Health-e]Antiretrovirals continue to be the most reported medicine out of stock as the civil society Stop Stock Out Project continues, write Project Coordination Monique Lines and Medicines Sans Frontieres pharmacist Tinne Gils. (Source: AllAfrica News: HIV-Aids and STDs)
Africa: Channel 4 Wrong to Claim Cancer Is Bigger Than Aids
[Africa Check]Does cancer kill more people in Africa than malaria, tuberculosis and HIV/Aids combined? No. Editors of a Channel 4 programme in the UK tell Africa Check they were wrong and are withdrawing the claim. (Source: AllAfrica News: Health and Medicine)
Africa: A Flurry of Interest Greets Closure of First Window for Regional Proposals Under NFM
[GFO]Forty-three entities, seeking funds exceeding $689 million, have signaled interest (Source: AllAfrica News: HIV-Aids and STDs)
Kenya: HIV-Aids Cases On the Rise in Kisii
[The Star]Kisii Governor James Ongwae's wife yesterday expressed concern over increased cases of HIV-Aids infections in the county. Elizabeth Ongwae said statistics from Aids Indicator Survey, 2012 and National Demographic and Health Survey show the county recorded 5,480 new infections. "The county is listed along Kisumu, Homa Bay, Siaya, Mombasa and Nairobi as most hit by the virus," Elizabeth said. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Namibia: Strong Link Between GBV, Alcohol and HIV
[New Era]Windhoek -Many countries have HIV and gender-based violence (GBV) policy frameworks on how to overcome the burden of the two epidemics, but they do not interweave alcohol abuse into their policies though the latter could lead to HIV. (Source: AllAfrica News: HIV-Aids and STDs)
MMWR Surveillance Summary: Youth Risk Behavior Surveillance - United States, 2013
The Youth Risk Behavior Surveillance?United States, 2013 (YRBS) collected data from state and large urban school districts related to health-risk behaviors that contribute to the leading causes of death, disability, and social problems among youth and adults. (Source: CDC HIV/AIDS Prevention)
Updated: Infographics and Posters for 2014 National HIV Testing Day
New National HIV Testing Day Resources for print and social media. (Source: CDC HIV/AIDS Prevention)
Zimbabwe: Young Zimbabweans Miss Out On HIV Testing
[IRIN]Harare -Young people with HIV are dying in increasing numbers in Zimbabwe at a time when HIV-related deaths are declining for all other age groups. (Source: AllAfrica News: HIV-Aids and STDs)
Tanzania: Having Bike in-Hand Is Enough for World Tour
[Daily News]EXACTLY ten years after Somen Debnath started his bicycle tour in his Indian homeland, he arrived in Dar es Salaam. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Rwanda: First Lady Reaffirms Resolve to End HIV Stigma
[New Times]First Lady Jeannette Kagame has urged all Rwandans, irrespective of status in society, to join the fight against HIV/Aids, saying it is crucial to ensure that HIV-positive persons are not stigmatised. (Source: AllAfrica News: HIV-Aids and STDs)
Nigeria: HIV/Aids Prevalence Drops to 1.3 Percent in Kano
[Vanguard]Kano-- HIV and AIDS prevalence has dropped from 2.8 per cent to 1.3 per cent in Kano State, according to a survey conducted by the National AIDS and Reproductive Health Survey Plus, NARHS-Plus. (Source: AllAfrica News: HIV-Aids and STDs)
Economic evaluation of surgical insertion of ventilation tubes for the management of persistent bilateral otitis media with effusion in children
Conclusions: The VTs strategy is a cost-effective option when compared with the HAs alone and HAs plus VTs strategies, but the need for additional information from future study is evident to inform this surgical treatment choice. Future studies of surgical and non-surgical treatment of OME in childhood should evaluate the economic impact of pertinent interventions to provide greater context. (Source: BMC Health Services Research)
Youth risk behavior surveillance - United States, 2013.
This report summarizes results for 104 health-risk behaviors plus obesity, overweight, and asthma from the 2013 national survey, 42 state surveys, and 21 large urban school district surveys conducted among students in grades 9-12. Results: Results from the 2013 national YRBS indicated that many high school students are engaged in priority health-risk behaviors associated with the leading causes of death among persons aged 10-24 years in the United States. During the 30 days before the survey, 41.4% of high school students nationwide among the 64.7% who drove a car or other vehicle during the 30 days before the survey had texted or e-mailed while driving, 34.9% had drunk alcohol, and 23.4% had used marijuana. During the 12 months before the survey, 14.8% had been electronically bullied, 19....
Myasthenia Gravis: Paradox versus paradigm in autoimmunity.
Authors: Berrih-Aknin S Abstract Myasthenia Gravis (MG) is a paradigm of organ-specific autoimmune disease (AID). It is mediated by antibodies that target the neuromuscular junction. The purpose of this review is to place MG in the general context of autoimmunity, to summarize the common mechanisms between MG and other AIDs, and to describe the specific mechanisms of MG. We have chosen the most common organ-specific AIDs to compare with MG: type 1 diabetes mellitus (T1DM), autoimmune thyroid diseases (AITD), multiple sclerosis (MS), some systemic AIDs (systemic lupus erythematous (SLE), rheumatoid arthritis (RA), Sjogren's syndrome (SS)), as well as inflammatory diseases of the gut and liver (celiac disease (CeD), Crohn's disease (CD), and primary biliary cirrhosis (PBC)). Several ...<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
The cascade of care in the Eastern European country of Georgia
ConclusionsThe findings of our analysis demonstrate that the majority of patients diagnosed with HIV infection are retained in care. Loss of patients occurs at each step of the HIV care continuum, but the major gap is at the stage of HIV diagnosis. Reducing the number of persons living with undiagnosed HIV infection and simultaneously enhancing engagement in continuous care will be critical to achieve maximum individual and public health benefits of ART. (Source: HIV Medicine)
Switching from Efavirenz to Nevirapine in Children: 1-Week Dose Escalation Strategy
AIDS Research and Human Retroviruses , Vol. 0, No. 0. (Source: AIDS Research and Human Retroviruses)
Expression and Localization of P-Glycoprotein, Multidrug Resistance Protein 4, and Breast Cancer Resistance Protein in the Female Lower Genital Tract of Human and Pigtailed Macaque
AIDS Research and Human Retroviruses , Vol. 0, No. 0. (Source: AIDS Research and Human Retroviruses)
Namibia: GBV, HIV Hand in Glove
[New Era]Women who experience violence in volatile abusive relationships face four times higher the risk of contracting HIV, an international study on the linkages between gender-based violence (GBV) and HIV has revealed. (Source: AllAfrica News: HIV-Aids and STDs)
Nigeria: Kano HIV/Aids Rate Drops to 1.3 Percent
[Daily Trust]Kano -Prevalence rate for HIV/AIDS in Kano State has dropped from 2.8 per cent to 1.3 per cent, according to a survey conducted by the National AIDS and Reproductive Health Survey Plus (NARHS-Plus), an organization saddled with the respon-sibility of monitoring the disease. (Source: AllAfrica News: Health and Medicine)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Kenya: NACC, Counties in Joint HIV-Aids Fight
[The Star]THE National Aids Control Council will incorporate the county governments in the new National HIV Strategic Framework to fight the spread of HIV-Aids. (Source: AllAfrica News: Health and Medicine)
Zimbabwe: Condom Uptake Must Cascade to Use
[The Herald]The HIV story should remain topical and the media has a role to have it remain visible, this was said by the Deputy Minister of Media, Information and Publicity Honourable Supa Mandiwanzira at an editor's briefing on the current HIV national response by the National Aids Council in conjuction with the Ministry of Health and Child Care in Chinhoyi recently. (Source: AllAfrica News: Health and Medicine)
Rwanda: Rights of People Living With HIV/Aids Are Guaranteed
[New Times]TODAY, the Rwanda Network of People living with HIV-better known as RRP+ (Réseau Rwandais des Personnes vivant avec le VIH) - marks its 10-year anniversary. This is an opportunity to acknowledge their achievements and valuable contribution towards the AIDS response in Rwanda. (Source: AllAfrica News: HIV-Aids and STDs)
Kenya: 15,000 Teachers Infected With HIV-Aids, Says NACC
[The Star]WE'LL FIGHT IT: Senior deputy director of education Margaret Murage and National Aids Control Council director Nduku Kilonzo at the Panafric Hotel, Nairobi during the launch of the TSC Kenepote best practices yesterday.Photo/Monicah Mwangi (Source: AllAfrica News: HIV-Aids and STDs)
Methods and protocol of a mixed method quasi-experiment to evaluate the effects of a structural economic and food security intervention on HIV vulnerability in rural Malawi: the SAGE4Health Study
DiscussionIn addition to examining pathways linking structural factors to HIV vulnerability, this research will yield important information for understanding the impact of a multilevel environmental/structural intervention on HIV, with the potential for other sustainable long-term public health benefits. (Source: BioMed Central)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Hepatitis B virus infection in a cohort of HIV infected blood donors and AIDS patients in Sichuan, China
Conclusions: High prevalence of HBV in HIV infected individuals was found in this study. Hence, we recommend routine testing of HBV for patients newly diagnosed with HIV/AIDS in China. Some HIV-HBV co-infected patients remain undiagnosed if only conventional serological markers for HBV are used and it's important to detect HBV DNA for HIV infected patients. HBV DNA levels were relatively low in HBeAg negative patients, thus this serologic marker may be useful in prioritizing patients on their need for HBV treatment in settings in which HBV DNA is not available. (Source: Journal of Translational Medicine)
Cell activation and HIV-1 replication in unstimulated CD4+ T lymphocytes ingesting exosomes from cells expressing defective HIV-1
Conclusions: Exosomes from cells expressing a functionally defective mutant can induce cell activation and HIV-1 susceptibility in unstimulated CD4+ T lymphocytes. This evidence highlights the relevance for AIDS pathogenesis of the expression of viral products from defective HIV-1 genomes. (Source: Retrovirology)
Acceptability of self-collection sampling for HPV-DNA testing in low-resource settings: a mixed methods approach
Conclusion: Self-and vaginal-sampling are widely acceptable among women in low-resource settings. Providers have a unique opportunity to educate and prepare women for self-sampling and be flexible in accommodating women's preference for self-sampling. (Source: BMC Public Health - Latest articles)
Structure?Based Studies on the Metal?Binding of Two?Metal?Dependent Sugar Isomerases
This article is protected by copyright. All rights reserved. Structured digital abstract BHRI and BHRI bind by x-ray crystallography (View interaction) (Source: FEBS Journal)
"It's Valid and Reliable" Is Not Enough: Critical Appraisal of Reporting of Measures in Trials Evaluating Patient Decision Aids
Conclusions. Very little is reported about the development or performance of measures used to evaluate the effectiveness of PtDAs in published trials. Minimum reporting standards are proposed to enable authors to prepare study reports, editors and reviewers to evaluate submitted papers, and readers to appraise published studies. (Source: Medical Decision Making)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Contributions of Second Opinions, Outcome Forecasts, and Testimonials to Patient Decisions about Knee Replacement Surgery
Conclusions. Information provided in a decision aid, including person-specific outcome forecasts and testimonials, can affect patient choices. The strong effect of testimonials and respondents&rsquo; interest in reviewing them reinforces concerns about unwanted influence when testimonials are biased. (Source: Medical Decision Making)
Why are we still, 20 years later, depriving human immunodeficiency virus-serodiscordant couples of equal access to fertility care?
Since acquired immunodeficiency syndrome (AIDS) was first described by the U.S. Centers for Disease Control and Prevention (CDC) in a group of five young gay men in 1981, more than 75 million people have contracted the human immunodeficiency virus (HIV) worldwide. There are currently more than 35 million people living with HIV/AIDS, with 2.3 million new infections reported in 2012. Over 80% of people infected with HIV are of reproductive age (15?44 years old), and heterosexual transmission accounts for up to 80% of all new infections in women. (Source: Fertility and Sterility)
Text Reminders Improve Adherence to Antiretroviral TherapyText Reminders Improve Adherence to Antiretroviral Therapy
When a text reminder is sent to patients who do not open their pill container within 30 minutes of a scheduled dose, adherence to antiretroviral therapy improves significantly, new research shows. Medscape Medical News (Source: Medscape Medical News Headlines)
Editorial Board
(Source: Journal of the Association of Nurses in AIDS Care)
Masthead
(Source: Journal of the Association of Nurses in AIDS Care)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Table of Contents
(Source: Journal of the Association of Nurses in AIDS Care)
Board of Directors
(Source: Journal of the Association of Nurses in AIDS Care)
Simplified Submission
Never throw up on an editor.Ellen Datlow (as cited in ) I'm a nurse. No one thought to teach me about business or publishing or the business of publishing. It was hard enough to teach me the skills and the theories of nursing. Who knew I'd grow up to edit a journal? I learned how to write and edit somewhere along the way; after all, nursing is a career of many challenges and opportunities. And now I am faced with the realization that being an editor (a perfectly good opportunity) has brought with it the challenge of the business of publishing. For those of you who have not been struggling with this as I have (and why would you?), the business of publishing is to get new information, new data, and new ideas out as quickly as possible in order to support the development of even more new inf...
Cover 1
(Source: Journal of the Association of Nurses in AIDS Care)
NIH Awards Scripps Research $13M Grant To Develop AIDS Vaccine
A research team from the The Scripps Research Institute (TSRI) has been awarded a grant of over $13 million from the National Institute of Allergy and Infectious Disease of the National Institutes of Health to research antibodies that could lead to the development of a vaccine against human immunodeficiency virus (HIV). (Source: Pharmaceutical Online News)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Africa: Civil Society Priorities Charter Drives Inclusive Country Dialogue in Southern Africa
[GFO]Concept note development for Global Fund grants advances using participatory approach, group says (Source: AllAfrica News: HIV-Aids and STDs)
Africa: Global Health Will Remain Top Priority for Development Funding in a Post-MDG World - Benn
[GFO]'Getting to Zero' with high-impact, high value-for-money programs at core of Global Fund's agenda now and post-2015 (Source: AllAfrica News: HIV-Aids and STDs)
Malawi: Henry's Story - 'HIV Has Made Me Fearless'
[Key Correspondents]At the age of 18 Henry, from Blantyre in Malawi, was shocked to discover he had been living with HIV all his life. Henry (not his real name) talks about how he has come to terms with his status. (Source: AllAfrica News: HIV-Aids and STDs)
Nigeria: Agency to Distribute Three Million Mosquito Nets in Bauchi
[Leadership]The Bauchi Agency for the Control of HIV/AIDs,Tuberculosis, Leprosy and Malaria (BACATMA) says it has concluded arrangements for the distribution of 3.2 million Long Lasting Mosquito Nets (LLMN) in the state. (Source: AllAfrica News: Malaria)
Cognitive aids: time for a change?
(Source: Anaesthesia)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
The effects of a displayed cognitive aid on non?technical skills in a simulated ?can't intubate, can't oxygenate? crisis
In this study, 64 participants were randomly assigned into control (no cognitive aid) and intervention (cognitive aid provided) groups before a simulated ?can't intubate, can't oxygenate? scenario. Video analysis was undertaken of the non?technical skills and technical performance during the scenarios. All categories had higher Anaesthetists? Non?Technical Skills (ANTS) scores when a cognitive aid was supplied (mean (SD) total ANTS score 10.4 (3.1) vs 13.2 (2.4), p &lt; 0.001). The number of times the cognitive aid was used was associated with higher ANTS scores (? = 0.383, p = 0.002). A trend towards the establishment of an infraglottic airway within 3 min was also noted (control group 55.3% vs intervention 76.9%, p = 0.076). Non?technical skills are improved when a ...
Physical Therapy as an Adjunct Treatment for People Living with HIV/AIDS An Allied Health Perspective
This article is currently available as a free download on ingentaconnect (Source: Journal of Allied Health)
Vulnerabilities, impacts and responses to HIV/AIDS in sub-Saharan Africa.
Authors: Wamoyi J PMID: 24917515 [PubMed - as supplied by publisher] (Source: Culture, Health and Sexuality)
Prevalence of Metabolic Syndrome Among Antiretroviral-Naive and Antiretroviral-Experienced HIV-1 Infected Thai Adults
AIDS Patient Care and STDs , Vol. 0, No. 0. (Source: AIDS Patient Care and STDs)
Ghana: Ghana Marks International Protect the Goal Day
[Ghanaian Chronicle]GHANA JOINS the world and the UNAIDS to mark the International Protect the Goal Day, just days away from the start of the 2014 Brazil World Cup. June 09, 2014 has been declared by the UNAIDS as the International Protect the Goal Day, and Executive Director Michel Sidibe will perform the global launch of the Day in in Salvador da Bahia in Brazil. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Circulating Plasma HIV-1 Viral Protein R in Dual HIV-1/Tuberculosis Infection
AIDS Research and Human Retroviruses , Vol. 0, No. 0. (Source: AIDS Research and Human Retroviruses)
Liberia: UN Agencies, Gov't Brainstorm
[NEWS]The United Nations Joint Program on HIV and AIDS (UNAIDS) and the United Nations Children's Fund (UNICEF) in collaboration with the Ministry of Health have concluded a weeklong Bottleneck Analysis on the current national Prevention from Mother to Child Transmission (PMTCT) plan in Buchanan, Grand Bassa County. (Source: AllAfrica News: Pregnancy and Childbirth)
Unboosted ATV vs Ritonavir-Boosted PI Maintenance TherapyUnboosted ATV vs Ritonavir-Boosted PI Maintenance Therapy
This meta-analysis compares unboosted atazanavir with ritonavir-boosted PI for long-term antiretroviral therapy in adults with virological suppression. HIV Medicine (Source: Medscape Today Headlines)
Kenya: Launch of HIV and Aids Documentary
[The Star]A documentary on the best practices on HIV/AIDS will be launched today by the education ministry. The documentary focuses on teachers living with HIV and their efforts towards zero new infections, stigma and discrimination, and HIV related deaths. (Source: AllAfrica News: HIV-Aids and STDs)
Liberia: UN, Govt Develop Scale-Up Plan
[New Dawn]The United Nations Joint Program on HIV and AIDS (UNAIDS) and the United Nations Children's Fund (UNICEF) in collaboration with the government of Liberia have concluded a weeklong Bottleneck Analysis on the current National Prevention from Mother to Child Transmission (PMTCT) plan in Buchanan, Grand Bassa. (Source: AllAfrica News: Health and Medicine)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Liberia: UNAIDS, UNICEF, Gov't Collaborate to Develop EMTCT Scale-Up Plan for Liberia
[Heritage]The United Nations Joint Program on AIDS (UNAIDS) and the United Nations Children's Fund (UNICEF) in collaboration with the Government of Liberia through the Ministry of Health and Social Welfare have concluded a weeklong Bottleneck Analysis on the current national Prevention from Mother to Child Transmission (PMTCT) plan in Buchanan, Grand Bassa County. (Source: AllAfrica News: Pregnancy and Childbirth)
Namibia: HIV/Aids Down On Priority List
[New Era]The Head of the HIV/AIDS Management Unit (HAMU) in the Ministry of Education says HIV/AIDS issues are being "pushed under the carpet and nobody wants to talk about it," unlike in the past when HIV/AIDS dominated public discussions. (Source: AllAfrica News: HIV-Aids and STDs)
Kenya: 13,000 Babies Born With HIV Each Year
[The Star]THE Ministry of Health yesterday released worrying statistic indicating that about 13,000 newborns are born with HIV annually in the country. (Source: AllAfrica News: HIV-Aids and STDs)
Angola: HIV/Aids Cases Increase in Bengo
[ANGOP]Caxito -At least 28 new cases of HIV/Aids were diagnosed, in the first quarter of this year in Caxito, northern Bengo Province by the Voluntary Testing Centre (CATV), announced on Monday to Angop, the provincial coordinator of Fight against Aids, Gabriela Abreu. (Source: AllAfrica News: HIV-Aids and STDs)
Gene editing tool can write HIV out of the picture
The latest form of genetic engineering can give human cells a rare mutation that keeps them HIV-free (Source: New Scientist - HIV and AIDS)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Influence of professional preparation and class structure on HIV, STD, and pregnancy prevention education
Conclusion: Findings from the current study support the need for professionally prepared educators and stand-alone class structure in terms of providing the most effective sexual health education. (Source: Health Education Journal)
African American Race and HIV Virological Suppression: Beyond Disparities in Clinic Attendance
Racial disparities in clinic attendance may contribute to racial disparities in plasma human immunodeficiency virus type 1 (HIV-1) RNA levels among HIV-positive patients in care. Data from 946 African American and 535 Caucasian patients receiving HIV care at the University of North Carolina Center for AIDS Research HIV clinic between January 1, 1999, and August 1, 2012, were used to estimate the association between African American race and HIV virological suppression (i.e., undetectable HIV-1 RNA) when racial disparities in clinic attendance were lessened. Clinic attendance was measured as the proportion of scheduled clinic appointments attended (i.e., visit adherence) or the proportion of six 4-month intervals with at least 1 attended scheduled clinic appointment (i.e., visit constancy)....
Cohort Profile: Antiretroviral Therapy Cohort Collaboration (ART-CC)
The advent of effective combination antiretroviral therapy (ART) in 1996 resulted in fewer patients experiencing clinical events, so that some prognostic analyses of individual cohort studies of human immunodeficiency virus-infected individuals had low statistical power. Because of this, the Antiretroviral Therapy Cohort Collaboration (ART-CC) of HIV cohort studies in Europe and North America was established in 2000, with the aim of studying the prognosis for clinical events in acquired immune deficiency syndrome (AIDS) and the mortality of adult patients treated for HIV-1 infection. In 2002, the ART-CC collected data on more than 12,000 patients in 13 cohorts who had begun combination ART between 1995 and 2001. Subsequent updates took place in 2004, 2006, 2008, and 2010. The ART-CC data b...
Occurrence of intestinal microsporidia in immunodeficient patients in Poland.
This article presents the results of the first epidemiological study on the ccurrence and prevalence of microsporidia in patients with primary and secondary immunodeficiency in Poland. PMID: 24959769 [PubMed - in process] (Source: Annals of Agricultural and Environmental Medicine : AAEM)
HIV/AIDS in Rural America: Disproportionate Impact on minority and Multicultural Populations
Overview of the impact of AIDS and HIV in rural areas. Summarizes the epidemiology of AIDS/HIV, including its impact on rural minority groups. Discusses the challenges rural areas face in preventing AIDS. Includes policy recommendations. -- National Rural Health Association (Source: Rural publications via the Rural Assistance Center)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Sleep may help memories form by promoting new synapses
Research in mice suggests that sleep aids memory by promoting the formation of new nerve cell connections Continue reading... (Source: Guardian Unlimited Science)
Zimbabwe: Children Battle to Access HIV Testing
[IRIN]Harare -Young people with HIV are increasingly dying at a time when HIV-related deaths are declining for all other age groups. They are also less likely to get tested for the virus, as concerns about guardianship and privacy can discourage clinics from testing children, according to a recent study. (Source: AllAfrica News: HIV-Aids and STDs)
9th International Conference on HIV Treatment and Prevention Adherence9th International Conference on HIV Treatment and Prevention Adherence
Read clinically focused news coverage of key developments from IAPAC 2014. Medscape HIV/AIDS (Source: Medscape Today Headlines)
Video game technology aids horse rider assessment
Horse riders? balance, symmetry and poor posture could be improved thanks to an innovative body suit that works with motion sensors, commonly used by movie makers and the video games industry. New research uses inertial motion sensors worn in the XsensTM MVN body suit, and is now showing promising results as a method of assessing rider asymmetry and lower back pain and injury risk. (Source: ScienceDaily Headlines)
Liberia: Liberia Works With Partners Towards EMTCT Deadline
[Analyst]Monrovia -The United Nations Joint Program on HIV and AIDS (UNAIDS) and the United Nations Children's Fund (UNICEF) in collaboration with the Government of Liberia through the Ministry of Health and Social Welfare have concluded in Buchanan a weeklong Bottleneck Analysis on the current national Prevention of the deadly disease from Mother to Child Transmission (PMTCT) Plan. (Source: AllAfrica News: Health and Medicine)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Nigeria: HIV Response - Experts Call for More Focus On Youths
[Vanguard]VOluntary HIV screening has never been a strong issue with the younger generation. Since most young people with HIV do not know their status, it is vital that youth at risk for HIV be tested and know where to get a confidential HIV test. (Source: AllAfrica News: HIV-Aids and STDs)
South Sudan: HIV Infection Rates Rising in Central Equatoria, Officials Say
[Sudan Tribune]Morobo -The rate of HIV infections in Central Equatoria state's Morobo county significantly increased this year compared to last year's statistics, a health official said. (Source: AllAfrica News: HIV-Aids and STDs)
Rwanda: HIV Prevalence Rate Worries MPs
[New Times]Even as the country registered a big reduction in the HIV/Aids infection rates, legislators have expressed worry over the current prevalence rates, saying more should be done to fight the global pandemic. (Source: AllAfrica News: Health and Medicine)
Africa: UN Officials Urge Greater Commitment, Investment, Innovation to End HIV/Aids Epidemic
[UN News]Despite significant gains, the HIV/AIDS epidemic is far from over, United Nations officials said today, calling for greater political commitment, investment and innovation to end the global scourge. (Source: AllAfrica News: Health and Medicine)
Zimbabwe: Blind, Inspirational Taffy Needs Your Votes
[New Zimbabwe]A ZIMBABWEAN man who grew up in an orphanage and lost his sight some five years ago but now runs an organisation that provides HIV education to the blind and helps them use computers is up for a top international award and needs the votes of fellow Zimbabweans. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Impact of ART Response on Life Expectancy in HIV+ AdultsImpact of ART Response on Life Expectancy in HIV+ Adults
This study estimates life expectancies of HIV-positive patients according to response to antiretroviral therapy. AIDS (Source: Medscape Today Headlines)
Kenya: Man Wrongly Diagnosed With HIV and TB Sues KNH
[The Star]A man is suing Kenyatta National Hospital and five doctors for allegedly misdiagnosing him with HIV in 2006. Peter Mungai Njoroge received Tubercolusis and HIV treatment for several months before he was told that he never actually had the virus that causes AIDS. (Source: AllAfrica News: HIV-Aids and STDs)
Activity aids breast cancer survival
Exercise can aid recovery after breast cancer but many women are not active enough, a study suggests. (Source: BBC News | Health | UK Edition)
Malawi: COWLHA Malawi Shifting Perceptions of Masculinity, Feminity in Dowa
[Malawi News Agency]The coalition of Women Living with HIV and AIDS (COWLHA) Malawi has said gender based violence makes women more vulnerable to HIV and AIDS which is fuelled by negative societal perceptions. (Source: AllAfrica News: HIV-Aids and STDs)
Innate DNA sensing is impaired in HIV patients and IFI16 expression correlates with chronic immune activation
Summary The innate immune system has been recognized to play a role in the pathogenesis of HIV infection, both by stimulating protective activities and through a contribution to chronic immune activation, the development of immunodeficiency and progression to AIDS. A role for DNA sensors in HIV recognition has been suggested recently, and the aim of the present study was to describe the influence of HIV infection on expression and function of intracellular DNA sensing. Here we demonstrate impaired expression of interferon?stimulated genes in responses to DNA in peripheral blood monuclear cells from HIV?positive individuals, irrespective of whether patients receive anti?retroviral treatment. Furthermore, we show that expression levels of the DNA sensors interferon?inducible protein ...<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
A theoretical model to describe progressions and regressions for exercise rehabilitation
This article aims to describe a new theoretical model to simplify and aid visualisation of the clinical reasoning process involved in progressing a single exercise. Exercise prescription is a core skill for physiotherapists but is an area that is lacking in theoretical models to assist clinicians when designing exercise programs to aid rehabilitation from injury. Historical models of periodization and motor learning theories lack any visual aids to assist clinicians.The concept of the proposed model is that new stimuli can be added or exchanged with other stimuli, either intrinsic or extrinsic to the participant, in order to gradually progress an exercise whilst remaining safe and effective. The proposed model maintains the core skills of physiotherapists by assisting clinical reasoning sk...
Stat
"Sound Medicine's" Eric Metcalf takes a look at medicine by the numbers in the new series, Stat. This week Metcalf explores the ways HIV/AIDS is portrayed by actors and actresses on screen..... (Source: Sound Medicine)
A genotypic HIV-1 proviral DNA coreceptor tropism assay: characterization in viremic subjects.
CONCLUSIONS: Our findings demonstrate that proviral DNA tropism determinations from whole blood or peripheral blood mononuclear cells were highly concordant with plasma HIV-1 RNA tropism determinations. This assay may be useful for screening virologically suppressed patients for CCR5-antagonist eligibility and for research purposes. PMID: 24904682 [PubMed] (Source: AIDS Research and Therapy)
Viral and cellular factors underlying neuropathogenesis in HIV associated neurocognitive disorders (HAND).
Authors: Rao VR, Ruiz AP, Prasad VR Abstract As the HIV-1 epidemic enters its fourth decade, HIV-1 associated neurological disorders (HAND) continue to be a major concern in the infected population, despite the widespread use of anti-retroviral therapy. Advancing age and increased life expectancy of the HIV-1 infected population have been shown to increase the risk of cognitive dysfunction. Over the past 10 years, there has been a significant progress in our understanding of the mechanisms and the risk factors involved in the development of HAND. Key events that lead up to neuronal damage in HIV-1 infected individuals can be categorized based on the interaction of HIV-1 with the various cell types, including but not limited to macrophages, brain endothelial cells, microglia, astro...
A single aspergillus fumigatus intracranial abscess in an immunocompetent patient with parietal lobe tumorectomy
We report here a rare case of intracranial aspergillosis in a patient who had previously undergone a parietal lobe tumorectomy. Aspergillus fumigatus was confirmed by histopathology, and susceptibility tests reported that this infection should respond to voriconazole. We believe the immunosuppression resulting from surgical trauma and glucocorticosteroid treatment may be contributing to the infection, and therefore management of these two factors may improve the prognosis. (Source: BioMed Central)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Investigating active ingredients in a complex intervention: a nested study within the Patient and Decision Aids (PANDAs) randomised controlled trial for people with type 2 diabetes
Conclusion: The intervention was acceptable, flexible and readily implemented in primary care consultations. The decision aid was effective in facilitating cognitive processing. The intervention also facilitated rehearsal in preparation for active roles in a shared decision process.Trial registration: Trials Register Number: ISRCTN14842077. Date registered: 24.06.2010. (Source: BMC Research Notes)
Evaluation of Osteotomy Accuracy and Rotational and Angular Alignment for Cranial Closing Wedge Ostectomy Performed With and Without Alignment Aids
ConclusionsK?wires can be used successfully as alignment aids during CCWO and help to create a significantly more orthogonal osteotomy. This allows a significant reduction in the difference between the preoperative and postoperative angles of valgus or varus, which may reduce the risk of developing a clinically important iatrogenically introduced valgus/varus deformity postoperatively. (Source: Veterinary Surgery)
International Cooperation on Key Issues Fell in 2013
By Jim LobeWASHINGTON, Jun 6 2014 (IPS) International cooperation on key global challenges declined in 2013, according to a new ?report card? released here Friday by the influential Council on Foreign Relations (CFR). Particularly disappointing were international efforts in dealing with terrorism, nuclear non-proliferation and global finance, according to the report which, however, found some gains in two areas ? dealing with or preventing armed conflict and improving global health. The report also found that cooperation on climate change, which last year?s report card found to be worth the lowest grade ? a ?D? &#8211; of all the major issues on which the report card focused, was neither better nor worse than the previous four years assessed by the 50-some experts who constit...
Second Generation Imaging of Nuclear/Cytoplasmic HIV-1 Complexes
AIDS Research and Human Retroviruses , Vol. 0, No. 0. (Source: AIDS Research and Human Retroviruses)
East Meets West: A Description of HIV-1 Drug Resistance Mutation Patterns of Patients Failing First Line Therapy in PEPFAR Clinics from Uganda and Nigeria
AIDS Research and Human Retroviruses , Vol. 0, No. 0. (Source: AIDS Research and Human Retroviruses)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
UN officials urge greater commitment, investment, innovation to end HIV/AIDS epidemic
Despite significant gains, the HIV/AIDS epidemic is far from over, United Nations officials said today, calling for greater political commitment, investment and innovation to end the global scourge. (Source: UN News Centre - Health, Poverty, Food Security)
The Health Behaviors of South Dakotans, 2012: A Report of the South Dakota Behavioral Risk Factor Surveillance System
Measures health risks of South Dakotans. Compares data from this survey to the Healthy People 2020 National Health Objectives as well as to the rest of the nation. Identifies populations at risk for poor health in the future. Topics include oral health, diabetes, health insurance, and HIV/AIDS among others. -- South Dakota Department of Health (Source: Rural publications via the Rural Assistance Center)
More Natural Artificial Vision for Retinal Prosthetic Devices
In laboratory tests, researchers have used electrical stimulation of retinal cells to produce the same patterns of activity that occur when the retina sees a moving object. Although more work remains, this is a step toward restoring natural, high-fidelity vision to blind people, the researchers say. The work was funded in part by the National Institutes of Health. (Source: Disabled World)
Malawi: Global Fund Close to Nearly Full Recovery of Malawi Refund
[GFO]Malawi has a $938,000 balance remaining on some $3.3 million it has been asked to return to the Global Fund following a 2010 audit (see GFO article). (Source: AllAfrica News: HIV-Aids and STDs)
Swaziland: Marriage a Barrier to ARVs for Women
[IPS]Mbabane -For months, Nonkululeko Msibi could not find her voice each time she wanted to share the news to her husband. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Bill Gates funding 'next generation' of skin-like super thin condoms to fight AIDS
Bill Gates, the world's richest man, has awarded an Australian university $100,000 in funding to develop skin-like condoms that can make men "want to wear one". (Source: The Independent - Science)
[World Report] Uganda takes ?another step backward? with HIV bill
Uganda recently passed a highly controversial HIV Prevention and Control Act that experts say will set back efforts to control HIV/AIDS in the country. Sharmila Devi reports. (Source: LANCET)
Diagnoses, prevalence, and state-based federal spending for HIV prevention and treatment in the United States, 2006-2009
Conclusions: Our findings suggest that state-based federal resource allocation for HIV prevention and treatment may be better aligned with HIV diagnosis and prevalence rates than previously reported; however resource allocation for HIV prevention is less aligned than funding for HIV treatment signaling the need to reexamine state-based federal funding for HIV prevention. (Source: AIDS Research and Therapy)
National Library of Medicine Announces Solicitation of Quotations for the 2014 HIV/AIDS Community Information Outreach Projects
The National Library of Medicine (NLM) is pleased to announce the solicitation of quotations from organizations and libraries to design and conduct projects that will improve access to HIV/AIDS-related health information for patients, the affected community, and their caregivers. Projects must involve one or more of the following information access categories: Information retrieval;&nbsp; Skills development;&nbsp; Resource development; and/or&nbsp; Equipment acquisition. Emphasis is placed upon the following types of organizations or arrangements for developing these programs: Community-based organizations (CBOs) or patient advocacy groups currently providing HIV/AIDS-related services to the affected community;&nbsp; Public libraries serving communities in the provision o...
June 8 is Caribbean-American HIV/AIDS Awareness Day
On June 8, AIDSinfo joins the nation in observing Caribbean-American HIV/AIDS Awareness Day. This day serves to raise awareness of HIV/AIDS in the Caribbean, a region disproportionately affected by this disease. According to the U.S Agency for International Development (USAID), outside of sub-Saharan Africa, the Caribbean region has the highest HIV prevalence in the world. In addition to raising awareness, the purpose of this day is to provide information and resources about HIV/AIDS to Caribbean Americans. Explore our Caribbean-American HIV/AIDS Awareness Day webpage [en espa&ntilde;ol] to learn more about the observance and to find information about HIV/AIDS in this region of the world. (Source: AIDSinfo At-a-Glance: Offering Information on HIV/AIDS Treatment, Prevention, and Research, ...<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Recent HIV/AIDS News from NIAID and FDA
News from NIAID June 2, 2014: Scientists Uncover Features of Antibody-Producing Cells in People Infected with HIV &quot;By analyzing the blood of almost 100 treated and untreated HIV-infected volunteers, a team of scientists has identified previously unknown characteristics of B cells in the context of HIV infection. B cells are the immune system cells that make antibodies to HIV and other pathogens. The findings augment the current understanding of how HIV disease develops and have implications for the timing of treatment.&quot; &nbsp; News from FDA &nbsp; &nbsp; &nbsp; May 30, 2014: June 17, Workshop on HIV Cure Research - Forum for Collaborative HIV Research &nbsp; &quot;On June 17, 2014, The Forum for Collaborative HIV Research will host an all-day workshop in Washington, DC at the K...
The Immunology Quality Assessment Proficiency Testing Program for CD3(+)4(+) and CD3(+)8(+) Lymphocyte Subsets: A ten year review via longitudinal mixed effects modeling.
Authors: Bainbridge J, Wilkening CL, Rountree W, Louzao R, Wong J, Perza N, Garcia A, Denny TN Abstract Since 1999, the National Institute of Allergy and Infectious Diseases Division of AIDS (NIAID DAIDS) has funded the Immunology Quality Assessment (IQA) Program with the goal of assessing proficiency in basic lymphocyte subset immunophenotyping for each North American laboratory supporting the NIAID DAIDS HIV clinical trials networks. Further, the purpose of this program is to facilitate an increase in the consistency of interlaboratory T-cell subset measurement (CD3(+)4pt+/CD3(+)8(+) percentages and absolute counts) and likewise, a decrease in intralaboratory variability. IQA T-cell subset measurement proficiency testing was performed over a ten-year period (January 2003 - July 2...
Hyperreactive malarious splenomegaly and aids: a case report.
Authors: Tano ZN, Filho CE, Breganó RM, Pavanelli WR, Ruzon UG PMID: 24911828 [PubMed - as supplied by publisher] (Source: Braz J Infect Dis)
Will There Be a Cure for HIV/AIDS?
The recent announcements of possible "cures" in two HIV-infected babies may herald a hopeful new phase for HIV research and treatment. (Source: WebMD Health)
Long-Term Control of Viral Replication in a Group O, Human Immunodeficiency Virus Type 1-Infected Individual
AIDS Research and Human Retroviruses Jun 2014, Vol. 30, No. 6: 511-513. (Source: AIDS Research and Human Retroviruses)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Short Communication: Lower Baseline CD4 Count Is Associated with a Greater Propensity Toward Virological Failure in a Cohort of South African HIV Patients
AIDS Research and Human Retroviruses Jun 2014, Vol. 30, No. 6: 531-534. (Source: AIDS Research and Human Retroviruses)
Comparison of Adherence Monitoring Tools and Correlation to Virologic Failure in a Pediatric HIV Clinical Trial
AIDS Patient Care and STDs Jun 2014, Vol. 28, No. 6: 296-302. (Source: AIDS Patient Care and STDs)
HIV/AIDS and STD Updates
AIDS Patient Care and STDs Jun 2014, Vol. 28, No. 6: 327-329. (Source: AIDS Patient Care and STDs)
Total Daily Pill Burden in HIV-Infected Patients in the Southern United States
AIDS Patient Care and STDs Jun 2014, Vol. 28, No. 6: 311-317. (Source: AIDS Patient Care and STDs)
Cumulative Effects of HIV Illness and Caring for Children Orphaned by AIDS on Anxiety Symptoms Among Adults Caring for Children in HIV-Endemic South Africa
AIDS Patient Care and STDs Jun 2014, Vol. 28, No. 6: 318-326. (Source: AIDS Patient Care and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Namibia: Decrease in New HIV Cases
[New Era]Windhoek -With new HIV infections on the decline the Ministry of Health and Social Services has attributed the positive trend to its efforts of increasing condom distribution across the country. For the 2013/2014 financial year, government spent close to N$20 million to procure 33 million condoms. Some 27.3 million of the procured condoms have already been distributed countrywide. The popular Smile condoms and femidoms (female condom) are distributed free of charge by government. "The HIV new infection rate is going (Source: AllAfrica News: HIV-Aids and STDs)
South Africa: Report - an Activist's Guide to Tuberculosis Drugs
[Health-e]Developed by the independent AIDS research and policy US-based think tank, the Treatment Action Group (TAG), the 32-page guide outlines tuberculosis (TB) drugs currently in use around the world. (Source: AllAfrica News: Tuberculosis)
Kenya: Fake Tinder Profile Promotes Sexual Health Awareness for June
[Capital FM]Men turning to Tinder recently may have found themselves talking to Nurse Nicole, a fake profile that turns flirty conversation into a serious talk about men's health for the month of June, which is Men's Health Month in the US. (Source: AllAfrica News: HIV-Aids and STDs)
Marriage a Barrier to ARV treatment for Swazi Women
This study has helped us understand why women are either dropping out or initiating ART late,? said Okello. The 2013 Global Report of the Joint United Nations Programme on HIV/AIDS (UNAIDS) shows that nine out of ten Swazis remain on ART after a year. But Okello said one dropout is one too many. ?We need to understand the barriers they encounter at social level so that we help them stay on treatment,? said Okello. Dlamini recommends empowering married women with skills to negotiate access to ART, and researching how some women successfully navigate this tricky situation. One such woman is Msibi, now 24, who is on treatment together with her husband. ?When my firstborn fell seriously ill, I realised I had to disclose,? she said. Counselling from health workers helped her find the ...
Malawi: Church and Society to Distribute New Female Condoms in Nkhata-Bay
[Malawi News Agency]Nkhata-Bay -Church and Society Programme of the Synod of Livingstonia will embark on a free distribution of new female condoms in Nkhata-Bay District, to empower the females in sexuality matters. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Addressing the Growing Cancer Burden in the Wake of the AIDS Epidemic in Botswana: The BOTSOGO Collaborative Partnership
Botswana has experienced a dramatic increase in HIV-related malignancies over the past decade. The BOTSOGO collaboration sought to establish a sustainable partnership with the Botswana oncology community to improve cancer care. This collaboration is anchored by regular tumor boards and on-site visits that have resulted in the introduction of new approaches to treatment and perceived improvements in care, providing a model for partnership between academic oncology centers and high-burden countries with limited resources. (Source: International Journal of Radiation Oncology * Biology * Physics)
Spatial analysis of factors associated with HIV infection among young people in Uganda, 2011
Conclusions: The study revealed associations between high-risk sexual behaviour and HIV infection. Behavioural change interventions should therefore be pertinent to the prevention of HIV. Spatial analysis further revealed a significant HIV cluster towards the Central and Eastern areas of Uganda. We propose that interventions targeting young people should initially focus on these regions and subsequently spread out across Uganda. (Source: BMC Public Health - Latest articles)
Reproductive desire in women with HIV infection in Spain, associated factors and motivations: a mixed-method study
Conclusions: The HIV-infected women interviewed in CoRIS have a high desire for children, and the factors associated with this desire are not fundamentally different from those of women in the general population. Maternity may even help them face a situation they still consider stigmatized and prefer not to disclose. Health-care protocols for handling HIV-positive women should incorporate specific interventions on sexual and reproductive health to help them fulfill their procreation desire and experience safe pregnancies. (Source: BMC Pregnancy and Childbirth - Latest articles)
Nutrition and Gaelic Football: Review, Recommendations and Future Considerations.
Authors: Beasley KJ Abstract Gaelic football is the second most popular team sport in Ireland in terms of participation. However, very little research exists on the nutritional considerations for elite male Gaelic footballers. Gaelic football is an intermittent type field game played by two teams of fifteen players. Although amateurs, elite players may train and compete 4-5 times per week and may play for several teams. Research suggests that elite footballers are similar anthropometrically and in fitness to professional soccer players. Work-rate analysis shows that footballers experience longer durations of high-intensity (HI) activity (5-7s) and shorter rest durations than soccer players. Recent data suggests that half-forwards/backs perform a greater amount of HI work during gam...
The Center for HIV/AIDS Vaccine Immunology (CHAVI) Multi-site Quality Assurance Program for Cryopreserved Human Peripheral Blood Mononuclear Cells.
Authors: Sarzotti-Kelsoe M, Needham LK, Rountree W, Bainbridge J, Gray CM, Fiscus SA, Ferrari G, Stevens WS, Stager SL, Binz W, Louzao R, Long KO, Mokgotho P, Moodley N, Mackay M, Kerkau M, McMillion T, Kirchherr J, Soderberg KA, Haynes BF, Denny TN Abstract The Center for HIV/AIDS Vaccine Immunology (CHAVI) consortium was established to determine the host and virus factors associated with HIV transmission, infection and containment of virus replication, with the goal of advancing the development of an HIV protective vaccine. Studies to meet this goal required the use of cryopreserved Peripheral Blood Mononuclear Cell (PBMC) specimens, and therefore it was imperative that a quality assurance (QA) oversight program be developed to monitor PBMC samples obtained from study participant...<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Introduction for JIM Special Issue: Building Global Resource Programs to Support HIV/AIDS Clinical Trial Studies.
Authors: Sanchez AM, Denny TN, O'Gorman M PMID: 24910413 [PubMed - as supplied by publisher] (Source: Journal of Immunological Methods)
MSF Frontline Reports
In this edition, reports on how a neglected disease continues to cause blindness in people living with HIV/AIDS in Southeast Asia, on India's hidden war in Chhattisgarh state, and on the evolution of MSF's response to post-election violence in Kenya. (Source: MSF News)
NLM Request for Quotations: HIV/AIDS Community Information Outreach Projects 2014
The National Library of Medicine (NLM) is pleased to announce the solicitation of quotations from organizations and libraries to design and conduct projects that will improve access to HIV/AIDS related health information for patients, the affected community, and their caregivers. Projects must involve one or more of the following information access categories: Information retrieval; Skills [&#8230;] (Source: NN/LM Middle Atlantic Region Blog)
Africa: Female Condoms, Cows that Smell Like Humans, and Touch-Screen Patient Feedback Tools Among New Gates-Funded Projects
[Gates Foundation] The Gates Foundation's Grand Challenges Explorations initiative rewards bold ideas to tackle global health and development challenges (Source: AllAfrica News: HIV-Aids and STDs)
Namibia: Youth Invited to Give Proposals On HIV, Aids Prevention Promotion
[New Era]Windhoek -The United States (US) Embassy in Namibia through the President's Emergency Plan for AIDS Relief, also known as PEPFAR is inviting any young person from school goers to non school goers to submit proposals for the promotion of Human Immunodeficiency Virus Infection / Acquired Immunodeficiency Syndrome (HIV/AIDS) prevention among the youth between the ages of 10 to 19 years. (Source: AllAfrica News: Health and Medicine)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Malawi: Phalombe Earmarked for Mobile Clinics
[Malawi News Agency]Phalombe -Phalombe District will soon have mobile clinics as one way of improving health services courtesy of Global Aids Interfaith Alliance (GAIA). Speaking at a recent District Executive Committee (DEC) Meeting that was held at the Boma, GAIA project officer, Alice Bvumbwe said the aim of the mobile clinic project is to prevent the spread of HIV and improve the quality of life of thousands of people living with HIV mostly in rural areas. (Source: AllAfrica News: HIV-Aids and STDs)
Uganda: Fewer Ugandans Dying of Aids - UAC
[Observer]Pallisa district leaders have reported a 0.2 per cent increase in the rate of new infections, bringing the rate of infection to 3.4 per cent from 3.2 in 2012. (Source: AllAfrica News: Health and Medicine)
Uganda: More Men Free With Sex Workers
[Observer]Some men find it easier to express themselves freely with sex workers than with their wives, a survey has found. (Source: AllAfrica News: HIV-Aids and STDs)
Tanzania: PLWAS in Katavi, Rukwa Find ARVs Uncomfortable
[Daily News]Sumbawanga -ABOUT 5,013 people living with HIV/Aids in Rukwa and Katavi regions have stopped taking anti-retroviral drugs (ARVs) for several reasons, one of them being that they feel uncomfortable taking them daily. (Source: AllAfrica News: Health and Medicine)
Starting out - Advocating for our friend drew on knowledge from my nurse training.
Authors: Price H Abstract During university training, we learned about the promotion of continence and the use of continence aids for patients who are unable to maintain their own elimination needs. PMID: 24894240 [PubMed - in process] (Source: Nursing Standard)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Informed Decision-Making Regarding Amputation for Complex Regional Pain Syndrome Type I.
CONCLUSIONS: Informed decision-making regarding amputation for CRPS-I remains a complex process for which little evidence is available to support patient choices; patient-specific outcomes are not predictable. However, amputation should not be ignored as a treatment option for long-standing therapy-resistant CRPS-I.LEVEL OF EVIDENCE: Therapeutic Level IV. See Instructions for Authors for a complete description of levels of evidence. PMID: 24897741 [PubMed - as supplied by publisher] (Source: The Journal of Bone and Joint Surgery. American volume)
Retrospective On The All-In-One Retroviral Nucleocapsid Protein.
Authors: Darlix JL, de Rocquigny H, Mauffret O, Mély Y Abstract This review aims at briefly presenting a retrospect on the retroviral nucleocapsid protein (NC), from an unspecific nucleic acid binding protein (NABP) to an all-in-one viral protein with multiple key functions in the early and late phases of the retrovirus replication cycle, notably reverse transcription of the genomic RNA and viral DNA integration into the host genome, and selection of the genomic RNA together with the initial steps of virus morphogenesis, respectively. In this context we will discuss the notion that NC protein has a flexible conformation and is thus a member of the growing family of intrinsically disordered proteins (IDP) where disorder may account, at least in part, for its functions as a nucleic ...
Visual enhancement of auditory beat perception across auditory interference levels.
This study dealt with audiovisual rhythm perception involving an observed movement. Two experiments investigated whether a visual beat conveyed by a bouncing human point-light figure facilitated beat perception of concurrent auditory rhythms, and whether this enhancement followed a profile of multisensory integration. In Experiment 1, participants listened to three repetitions of a metrically simple rhythm and detected a perturbation in the third repetition. The rhythm was presented alone or with a visual beat in phase to it. Both conditions were presented with or without an auditory interference sequence at four increasing tempi, which served to progressively weaken the beat of the auditory rhythm. In Experiment 2, participants tapped to a regular auditory beat in the same combinations of...
Spectrum of Non-Hodgkin Lymphoma in an Urban Ryan White-Funded Clinic in the Established Antiretroviral Era
AIDS Research and Human Retroviruses , Vol. 0, No. 0. (Source: AIDS Research and Human Retroviruses)

 

 


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