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CD4 Cells
By Afsath Jameela

CD4 Cells
Treatment centers need consulting rooms, offices, waiting rooms and secure storage for valuable drugs. They also require basic facilities to test for anemia, pregnancy, renal function, white blood cell counts and other factors that may affect treatment.
In developed countries, decisions about when to start treatment are based on the results of clinical tests called the CD4 test and the viral load test. Ideally these tests should be used everywhere, but in many parts of the world they are currently unavailable, as they require expensive equipment, electricity and trained technicians. In theory, decisions about when to start treatment may be based on symptoms alone. However in practice some treatment programmers provide medication only to people who have had a CD4 count.
There are two primary types of T-cells.
1. CD4 Cells-These cells have molecules called CD4 on its surface. These "helper" cells initiate the body's response to invading micro-organisms such as viruses.
2.CD8 Cells-These types of T-cells have a molecule called CD8 on their surface. CD8 cells destroy cells that have been infected with foreign invading micro-organisms. CD8 cells also produce antiviral substances (antibodies) that help fight off the foreign invader.
3.Normal values-In a healthy adult, a normal CD4 count can vary a great deal but is typically 600 to 1200 cells per cubic millimeter of blood
Between 600 and 350- In an HIV+ person, this range is considered "very good".
HIV medications are typically not be indicated.
Between 350 and 200-The immune system is weakened and therefore the HIV+ person may be at increased risk for infection and illness.
Function of T helper cells: Antigen presenting cells present antigen on their Class II MHC molecules. Helper T cells recognize these, with the help of their expression of CD4 co-receptor. The activation of a resting helper T cell causes it to release cytokines and other stimulatory signals. The importance of CD4 T cells is demonstrated with infection.
It has been proposed that during the non-symptomatic phase of infection, the virus has a relatively low affinity towards T cells (and has a higher affinity for macrophages), resulting in a slow kill rate of CD4+ T cells by the immune system. This is initially compensated for via the production of new helper T cells from thymus. Once the virus becomes T-tropic, it begins to infect CD4+ T cells far more efficiently, and

Keep an eye out for signs to prevent suicides: Doctors - Asian Age: Mumbai
Following the six suicides by jumping off the Bandra-Worli sealink in the past one month, psychiatrists and mental health experts in the city are now advising keeping a lookout for tell-tale signs to prevent such incidents. By tell-tale signs, they mean general indicators that can be observed in the behaviour of a person contemplating suicide as a way of escaping his/her circumstances. These include talking about dying most of the time, being in a state of hopelessness, excessive anxiety, increase in consumption of alcohol, sleeping too much or too less, seeking refuge in isolation and showing rage or seeking revenge. According to experts, the signs are easily identifiable and should not be ignored. Rather, persons exhibiting such behaviours should be taken to a counsellor at once. Explaining the case of a schoolgoing boy, Dr Harish Shetty, consultant psychiatrist with Hiranandani Hospital, said ?The 12-year-old boy had performed badly in his exams. He came home with his report card and handed it over to ...
MBBS students urged to excel - The Telegraph : North East
Tezpur, Sept. 1: Sonitpur deputy commissioner Lalit Gogoi today urged the first batch of MBBS students in Tezpur Medical College to work hard and become a part of the country's dedicated healthcare force.
Auto driver rapes 15-year-old girl - deccanherald.com
A 15-year-old mentally challenged girl was raped by an auto driver at east Delhi's Ghazipur during the wee hours of Monday. Police have been unable to ascertain the identity of the victim and a team has been constituted to identify her. Auto driver Ramashish, 35, was caught by a police team patrolling in a police control room van. The policemen noticed a parked autorickshaw near the Ghazipur flyover. Sensing something suspicious, they searched the vehicle and then a forested area near it. As they neared the forested area, they heard a girl's screams for help. They searched and found the auto driver raping the girl. She was rescued and taken to Ghazipur police station along with the accused. The girl was unable to speak anything and police said she was in a state of shock. She has not even been able to tell her name or her address. Police then turned their attention towards the driver who confessed to his crime. "Ramashish said he was waiting near Anand Vihar railway station when he noticed the girl. He ...
Doctors declare living patient as dead in Aligarh hospital - Hindustan Times: India
Doctors in a hospital in Aligarh declared a patient who was admitted there for treatment as dead When the police arrived three days later the patient was lying in the mortuary ...
Mentally-challenged teenage girl raped by auto driver in Delhi - deccanherald.com
A mentally-challenged teenage girl was allegedly raped by an auto-rickshaw driver in the wee hours on Monday in East Delhis Ghazipur area, police said. The incident came to light when staff of a PCR van which was patrolling in the area found an auto abandoned in the middle of the road. While searching for its owner, they found the accused, Ram Ashish, sexually assaulting the girl. "The PCR van personnel found the auto parked near the Ghazipur flyover around 4:30 AM. When they went looking for its owner in a nearby forest, they heard a girl screaming and immediately rushed to the spot," a police official said. "The girl was rescued and Ashish was taken into custody," he added. The oficial said Ashish on interrogation told police that he saw the girl near Anand Vihar Railway station and lured her on the pretext of dropping her at Sarai Kale Khan. He then stopped his auto near the flyover where he raped the girl. A case against the auto driver under Section 376 (rape) of IPC and Prevention of Children from ...
Michael Jackson?s children celebrate his birthday in hometown - FirstPost: Bollywood
<p>King of Pop Michael Jackson's children went to his hometown Gary in Indiana to celebrate what would have been his 56th birthday.</p> <p>The post <a rel="nofollow" href="http://www.firstpost.com/bollywood/michael-jacksons-children-celebrate-birthday-hometown-1692143.html">Michael Jackson&#8217;s children celebrate his birthday in hometown</a> appeared first on <a rel="nofollow" href="http://www.firstpost.com">Firstpost</a>.</p>
All districts to get suicide helpline - The Hindu: Today's Paper
All districts to get suicide helpline
Michael Jackson?s children celebrate his birthday in hometown - Hindu: Home
King of Pop Michael Jackson?s children went to his hometown Gary in Indiana to celebrate what would have been his 56th birthday. The late star?s kids Prince, 17, Paris, 16, and Blanket, 1...
Fifi admits to never telling dad-Bob Geldof about 'mental illness' - New Kerala: World News
London (UK), Aug 31 : Fifi Geldof, the eldest daughter of music legend Bob Geldof, has admitted that she never told her father about her lifelong battle with depression.
Awards for films on mental health - Hindu: News
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All districts to get a suicide helpline - Hindu: National
In the wake of increasing number of suicides, a helpline has been planned in each district, including Bangalore, which reportedly has the highest suicide rate in the State. Some counsellors have c...
Ferguson's flashpoint sparks national outrage - Sify News
They were killed in Wisconsin, New York and California. Some were shot on the street. One was killed in a Wal-Mart. Another died after being placed in a chokehold. All died at the hands of police
Do you laugh to stop yourself from crying? - TOI: All Headlines
Do you laugh to stop yourself from crying?
I'll beat alcohol, says troubled Gascoigne - TOI: All Headlines
I'll beat alcohol, says troubled Gascoigne
'Set up day-care centres for the mental challenged in all districts' - Mysore - City - The Times of India
"As per norms, each district should have a minimum 20-bed facility, including 10 for de-addiction programme.
First health and wellness mall to come up in Jaipur: Bollywood actress ... - Daily News & Analysis - Jaipur News
First health and wellness mall to come up in Jaipur: Bollywood actress ... Daily News &amp; Analysis Bollywood actress and Padma Bhushan Awardee Sharmila Tagore on Sunday said India&apos;s first health and wellness mall would come up in Jaipur in the next two years. The health and fitness mall, to be built at a cost of Rs 110 to 120 cr, is specially ...
Workshop on parental skills - The Hindu: Today's Paper
Workshop on parental skills
Task force pushes for ‘Special Tuesday’ initiative - The Hindu: Today's Paper
Task force pushes for ‘Special Tuesday’ initiative
Woman’s body exhumed, re-postmortem conducted - The Hindu: Today's Paper
Woman’s body exhumed, re-postmortem conducted
Fifi admits to never telling dad-Bob Geldof about 'mental illness' - DNA: Top News
Fifi Geldof, the eldest daughter of music legend Bob Geldof, has admitted that she never told her father about her lifelong battle with depression. During an interview with Mail Online, the 31-year-old sister of late Peaches Geldof admitted that she has been battling depression since the age of eleven and it was Robin Williams&apos; shock suicide which inspired her to speak up, the Mirror reported. Stating that she never took medication to cure her illness, she said that her focus now was on her job and looking after her younger siblings after the death of her sister. Admitting that she does not share close relationship with her dad, Fifi further said that she trusted her friends more for support, and hence she did not tell Bob about her illness. The eldest daughter of Bob admitted that since the passing away of her sibling, her problems have deteriorated but she has urged others suffering from mental illness to follow her footsteps in speaking up about ...
2-day film fest to delve into the mind - Hindu: Cities
Organised by the Schizophrenia Research Foundation and Indo Cine Appreciation Foundation, it seeks to create awareness on mental illness
Woman?s body exhumed, re-postmortem conducted - Hindu: Cities
A team of doctors from the Government Rajaji Hospital (GRH) here exhumed the body of a 47-year-old woman at the Thathaneri burial ground and conducted a re-postmortem on Saturday.The re-pos...
G.O. on admission to special schools hailed - Hindu: Cities
?Special children must study beyond 18 years of age to overcome behavioural problems?
Two crushed to death by speeding vehicle - TOI: All Headlines
Two crushed to death by speeding vehicle
Panel moots schools for children with mental disorders - deccanherald.com
Karnataka State Mental Health Task Force will recommend to the State government to start schools for the residential care of children suffering from mental disorders in each district, Dr K A Ashok Pai, Chairman of the Task Force, said here on Saturday. The school with approximately 50 students, will work for the mental rehabilitation of these children, he said. Apart from it, residential care and rehabilitation centres for chronically ill mentally disabled patients in each district has also been proposed, he said. Speaking at a press meet, he said as per World Health Organisation, as many as 14 per cent of the population require counselling, or some form of treatment for mental health conditions. Even though a large chunk of the population faced these problems, awareness regarding mental health was low in the region. Awareness would play a key role in preventing the cases of suicide, which has increased in the past few years, he said. Noting that depression was one of the major reasons that pushed people ...

the immune system is overwhelmed.
At this point, functional CD4+ T cell levels begin to decrease, eventually to a point where the CD4+ T cell population is too small to recognize the full range antigens that could potentially be detected. The lack of full antigen cover results in the core symptoms of acquired immune deficiency syndrome (AIDS).CD4 T cell depletion during AIDS allows various pathogens to escape T cell recognition, thus allowing opportunistic infections that would normally elicit a helper T cell response to bypass the immune system. While these complete bypass situations only occur when the helper T cell response is absolutely necessary for infection clearance, most infections increase in severity and/or duration because the immune system's helper T cells provide a weaker contribution to a less efficient immune response.
Two components of the immune system are particularly affected in AIDS, due to its CD4+ T cell dependency:
CD8+ T cells are not stimulated as effectively during the AIDS period of infection, making AIDS patients very susceptible to most viruses, including itself. This decline in killing of CD4+ T cells results in the virus being produced for a longer period (the infected CD4+ T cells are not killed as quickly), increasing the proliferation of the virus, and accelerating the development of the disease.
Antibody class switching declines significantly once helper T cell function fails. The immune system loses its ability to improve the affinity of their antibodies, and are unable to generate B cells that can produce antibody groups such as IgG and IgA. These effects are primarily due to the loss of any helper T cell that can interact with the B lymphocyte correctly. Another symptom of AIDS is the reduction in antibody levels due to a decrease in Th2 cytokines (and less interactions by helper T cells). All of these complications result in an increased susceptibility to aggressive bacterial infections, especially in areas of the body not accessible by IgM antibodies.
If the patient does not respond to Treatment they will succumb usually to either cancers or infections; the immune system finally reaches a point where it is no longer coordinated or stimulated enough to deal with the disease.

 Keywords:  HIV,AIDS,HIV Cure,HIV Treatment,HIV Infection,HIV Dating,HIV Positive,HIV Symptoms.


Afsath Jameela is a successful lady writer from Kairo. She right now living in UK.

Africa: Global Fund News Flash - Issue 48
[Global Fund]Better Concept Notes, More Effective Funding (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Kenya: First Lady Urges Homa Bay to Fight HIV-Aids
[The Star]FIRST lady Margaret Kenyatta has urged fishermen and fishmongers to change their lifestyles in order to stop the spread of HIV-Aids. (Source: AllAfrica News: HIV-Aids and STDs)
Uganda: Universal Net Campaign Completed in Uganda, With US, UK and Global Fund Support
[Global Fund]Kampala -The U.S. Government, the United Kingdom (U.K.) Government and the Global Fund to Fight AIDS, Tuberculosis and Malaria sealed their commitment to the fight against malaria in Uganda today by finalizing their contribution to the Government of Uganda's Universal Coverage Campaign. Over 22 million long-lasting insecticide-treated nets (LLINs) for malaria prevention were distributed under the campaign, the largest universal coverage campaign worldwide, which began in the eastern part of the country and extended (Source: AllAfrica News: HIV-Aids and STDs)
Africa: Global Fund News Flash - Issue 47
[Global Fund]Zambia: Power of Partnerships (Source: AllAfrica News: HIV-Aids and STDs)
Nigeria: Medical Researcher Decries Low Patronage of HIV Prevention Services
[Leadership]A medical researcher, Prof. Oni Idigbe, on Friday expressed concern over the public's low patronage of Prevention of Mother-to-Children Transmission of HIV (PMTCT) services in Nigeria. (Source: AllAfrica News: HIV-Aids and STDs)
Kenya: HIV-Aids Myths Busted
[The Star]HIV-AIDS Myths busted Many people are afraid of HIV and for good reason. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
FACSCount CD4 and Pima CD4 T-Cell Count SystemsFACSCount CD4 and Pima CD4 T-Cell Count Systems
Which CD4 counting instrument is most reliable? JAIDS: Journal of Acquired Immune Deficiency Syndromes (Source: Medscape Today Headlines)
The Significance of Low-level Viraemia in Diverse SettingsThe Significance of Low-level Viraemia in Diverse Settings
This study reports on the association of low-level viraemia with viral failure in different economic settings. HIV Medicine (Source: Medscape Today Headlines)
Is Bone Loss Linked to Chronic Inflammation in HIV?Is Bone Loss Linked to Chronic Inflammation in HIV?
What role do inflammation and vitamin D play in HIV bone loss? AIDS (Source: Medscape Today Headlines)
Effectiveness of first-line antiretroviral therapy in the IPEC cohort, Rio de Janeiro, Brazil
Background: While Brazil has had a long-standing policy of free access to antiretroviral therapy (ART) for all in need, the epidemiological impact of ART on human immunodeficiency virus (HIV) RNA suppression in this middle-income country has not been well evaluated. We estimate first-line ART effectiveness in a large Brazilian cohort and examine the socio-demographic, behavioral, clinical and structural factors associated with virologic suppression. Methods: Virologic suppression on first-line ART at 6, 12, and 24 months from start of ART was defined as having a viral load measurement 8 years of formal education (compared to (Source: AIDS Research and Therapy)
Alcohol and cognitive impairment [Articles]
We present what is known about cognitive impairment associated with alcohol use/misuse, covering the spectrum from mild and subtle cognitive change through to severe alcohol-related brain damage, including Wernicke&ndash;Korsakoff syndrome. We highlight aids to the diagnosis and management of these conditions, and emphasise the benefits of prompt treatment on outcome. We also review progress in understanding their neurobiology. Suggestions for possible service configuration based on both our clinical practice and national guidelines are given. (Source: Advances in Psychiatric Treatment)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Antiretroviral treatment outcomes among foreign-born and Aboriginal peoples living with HIV/AIDS in northern Alberta.
CONCLUSIONS: Our study indicated that ART outcomes among Alberta-based foreign-born patients are similar to those among Canadian-born non-Aboriginal patients. Our results, however, suggested that Canadian-born Aboriginal patients had poorer treatment outcomes compared to Canadian-born non-Aboriginal patients. It is imperative, therefore, that clinicians, researchers and community members better understand reasons for poor ART outcomes among Canadian-born Aboriginal patients in northern Alberta. PMID: 25166126 [PubMed - in process] (Source: Canadian Journal of Public Health)
Patient, surgeon, and healthcare purchaser views on the use of decision and communication aids in orthopaedic surgery: a mixed methods study
Conclusions: Decision and communication aids can be effective tools for incorporating patients preferences and values into preference-sensitive decisions in orthopaedics. Future efforts should be aimed at assessing strategies for efficient implementation of these tools into widespread orthopaedic practice. (Source: BMC Health Services Research)
Australia's Seventh National HIV Strategy and the AIDS 2014 Legacy Statement.
Authors: Crooks L, Kidd MR PMID: 25163362 [PubMed - in process] (Source: Med J Aust)
Highlights from the 2014 International Symposium on HIV & Emerging Infectious Diseases (ISHEID): from cART management to the end of the HIV pandemic.
In this report we not only give details on this main topic but also summarize what has been discussed in the areas of HCV coinfection and present a short summary on currently emerging viral diseases. PMID: 25165483 [PubMed] (Source: AIDS Research and Therapy)
Porn productions suspended after performer tests positive for HIV
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Hiv/aids
The last issue of the Infectious Disease Clinics of North America devoted specifically to HIV/AIDS was published in 1988. Edited by Merle Sande and Paul Volberding, that landmark issue provided a state-of the-art snapshot of the newly defined epidemic, its epidemiology, and the basic principles of treatment and care. Much has happened since then. In 2012, the number of persons living with HIV infection worldwide reached an all-time high of 35.3 million. The medical, social, and economic consequences of this global disaster have reached all continents, presenting society with a health-related challenge unlike any other. (Source: Infectious Diseases Clinics of North America)
Global Epidemiology of HIV
The number of persons living with HIV worldwide reached approximately 35.3 million in 2012. Meanwhile, AIDS-related deaths and new HIV infections have declined. Much of the increase in HIV prevalence is from rapidly increasing numbers of people on antiretroviral treatment who are now living longer. There is regional variation in epidemiologic patterns, major modes of HIV transmission, and HIV program response. It is important to focus on HIV incidence, rather than prevalence, to provide information about HIV transmission patterns and populations at risk. Expanding HIV treatment will function as a preventive measure through decreasing horizontal and vertical transmission of HIV. (Source: Infectious Diseases Clinics of North America)
Forthcoming Issues
Updates in HIV and AIDS: Part II Michael S. Saag and Henry Masur, Editors (Source: Infectious Diseases Clinics of North America)
Porn star tests positive for HIV
An adult film performer tested positive for the AIDS virus, raising concern about adherence to safer sex policies on set (Source: Health News: CBSNews.com)
Malawi: APM Joins African Leaders to Show Commitment to the Fight Against HIV and Aids
[Malawi News Agency]Blantyre -President Professor Arthur Peter Mutharika on Thursday joined other 15 African Heads of State who have signed the 'Protect the Goal Campaign' as a sign of commitment to the fight against HIV and AIDS. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Sudan: Sudan Says Suspected Ebola Patient Died of Aids
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Liberia: NOCAL Supports 'Feed the Future'
[New Dawn]The National Oil Company of Liberia or NOCAL has provided several items to a local organization, 'Feed the Future,' as part of the ongoing Ebola fight. Items donated on Wednesday, 28 August include a consignment of Clorox, heavy duty rubber gloves and detergent soap. NOCAL also provided mattresses, buckets, clothing, assorted food items as well as other basic commodities. (Source: AllAfrica News: HIV-Aids and STDs)
Zimbabwe: Prophets Risk Arrest Over HIV Cure Claims
[New Zimbabwe]PROPHETS who claim to be able cure HIV/AIDS and other diseases such as cancer risk arrest for urging sufferers to stop taking their medications, a government minister said Thursday. (Source: AllAfrica News: HIV-Aids and STDs)
Zimbabwe: Wife Starves HIV+ Hubby
[The Herald]An HIV-positive man yesterday told the Harare Civil Court that his abusive wife forced him to sleep naked every night during the just-ended winter season despite telling her that he was feeling cold. (Source: AllAfrica News: HIV-Aids and STDs)
Serological response to 13-valent pneumococcal conjugate vaccine in children and adolescents with perinatally acquired HIV infection
Conclusion:Children with paHIV mount a robust serological response to PCV13 for most but not all vaccine serotypes. Viral load suppression with HAART and higher baseline IgG concentration are associated with higher postvaccination antibody levels. This has implications for HAART treatment and vaccination practices. (Source: AIDS)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Mobile app on emergency cardiac care aids best decisions in seconds
(European Society of Cardiology) The ACCA Clinical Decision-Making Toolkit mobile app is now available on the App Store and Google Play. (Source: EurekAlert! - Medicine and Health)
Zambia: Zambia Earns Kudos On PMTCT Gains
[Times of Zambia]ZAMBIA has been cited by the United Nations Programme on HIV/AIDS (UNAIDS) as one of the top seven best performing countries in the world in Prevention of Mother-to-Child Transmission (PMTCT). (Source: AllAfrica News: HIV-Aids and STDs)
Electrical stimulation 'aids memory'
Electromagnetic stimulation of a specific part of the brain may improve the ability to remember certain facts, researchers say. (Source: BBC News | Health | UK Edition)
FDA Approves New Fixed-Dose Combination Drug, Triumeq (Abacavir Sulfate/Dolutegravir/Lamivudine), to Treat HIV Infection
&quot;On August 22, 2014, FDA approved a new fixed-dose combination product: TRIUMEQ, a combination of dolutegravir (integrase strand transfer inhibitor), abacavir sulfate and lamivudine (both nucleoside analogue reverse transcriptase inhibitors) for the treatment of HIV-1 infection.&nbsp; &quot;TRIUMEQ alone is not recommended for use in patients with current or past history of resistance to any components of TRIUMEQ. &quot;TRIUMEQ alone is not recommended in patients with resistance-associated integrase substitutions or clinically suspected integrase strand transfer inhibitor resistance because the dose of dolutegravir in TRIUMEQ is insufficient in these subpopulations. See full prescribing information for dolutegravir.&nbsp; &quot;The recommended dosage regimen of TRIUMEQ in adult...
FDA Updates Etravirine Labeling
&quot;On August 20, 2014, the Intelence (etravirine) label was updated to include information regarding coadministration of etravirine with the following drugs: &quot;dolutegravir, dolutegravir/darunavir/ritonavir, dolutegravir/lopinavir/ritonavir &quot;atazanavir/ritonavir &quot;boceprevir&quot; The updated labeling for etravirine is available at the FDA website. More information is available: FDA: Press release AIDSinfo: Patient fact sheet on etravirine (Source: AIDSinfo At-a-Glance: Offering Information on HIV/AIDS Treatment, Prevention, and Research, A Service of the U.S. Department of Health and Human Services (DHHS))<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
News from CDC and NIAID
From CDC: August 27, 2014: New CDC Campaign Urges Latinos to Speak Up About HIV From NIAID: August 26, 2014: HIV Antibodies Block Infection by Reservoir-Derived Virus in Laboratory Study (Source: AIDSinfo At-a-Glance: Offering Information on HIV/AIDS Treatment, Prevention, and Research, A Service of the U.S. Department of Health and Human Services (DHHS))
Human Papillomavirus Vaccination.
This report summarizes the epidemiology of human papillomavirus (HPV) and associated diseases, describes the licensed HPV vaccines, provides updated data from clinical trials and postlicensure safety studies, and compiles recommendations from CDC's Advisory Committee on Immunization Practices (ACIP) for use of HPV vaccines. Persistent infection with oncogenic HPV types can cause cervical cancer in women as well as other anogenital and oropharyngeal cancers in women and men. HPV also causes genital warts. Two HPV vaccines are licensed in the United States. Both are composed of type-specific HPV L1 protein, the major capsid protein of HPV. Expression of the L1 protein using recombinant DNA technology produces noninfectious virus-like particles (VLPs). Quadrivalent HPV vaccine (HPV4) contains...
[Perspective] Rekindled HIV infection
What does the ?Mississippi baby? tell us about curing HIV-1 infection? Authors: Janet D. Siliciano, Robert F. Siliciano (Source: Science: Current Issue)
All-Cause and Cause-Specific Mortality Among U.S. Youth: Socioeconomic and Rural-Urban Disparities and International Patterns
An analysis of the socioeconomic and rural-urban disparities in all-cause mortality and mortality from homicide, suicide, unintentional injuries and HIV/AIDS among American youth. -- (Source: Rural publications via the Rural Assistance Center)
Programmed death-1 expression on HIV-1-specific CD8+ T cells is shaped by epitope specificity, T-cell receptor clonotype usage and antigen load
Conclusion:Collectively, these data suggest that PD-1 expression on HIV-1-specific CD8+ T cells tracks antigen load at the level of epitope specificity and TCR clonotype usage. These findings are important because they provide evidence that PD-1 expression levels are influenced by peptide/HLA class I antigen exposure. (Source: AIDS)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Hypothalamic-Pituitary-Adrenal Axis in HIV Infection and Disease
HIV infection induces hypothalamic-pituitary-adrenal (HPA) axis derangements. Partial glucocorticoid resistance has been observed in a subset of AIDS patients, possibly owing to HIV-induced altered cytokine secretion and action. Because glucocorticoids have immunomodulatory effects, the severity of the HPA axis disorder could play a central role in disease progression. The characteristic phenotype of AIDS patients (visceral obesity, lipodystrophy) may be owing to effects of HIV proteins on the HPA axis, including changes in glucocorticoid and insulin sensitivity of target tissues, as well as altered cytokine production and interaction with the HPA axis, genetic causes, comorbidities, and, possibly, use of antiretroviral agents. (Source: Endocrinology and Metabolism Clinics of North America...
From Wasting to Obesity, Changes in Nutritional Concerns in HIV/AIDS
Optimal nutrition is an important part of human immunodeficiency virus (HIV) care; to support the immune system, limit HIV-associated complications as well as maintain better quality of life and survival. The presentation and nature of malnutrition in patients with HIV has changed dramatically over the past 30 years from predominantly a wasting syndrome to lipodystrophy and, now, frailty. Nevertheless, we continue to see all 3 presentations in patient care today. The pathogenesis of poor nutrition in HIV-infected patients depends on caloric intake, intestinal nutrient absorption/translocation, and resting energy expenditure, which are features seen in all chronic diseases. (Source: Endocrinology and Metabolism Clinics of North America)
Africa: Does the Global HIV Response Understand Sex?
[IRIN]Melbourne -Stigma, squeamishness and misunderstanding of anal sex is leading to research gaps and inaccurate information about the risks of this common sexual behaviour, and hindering effective HIV/AIDS prevention strategies, experts say. A move towards "sex positive" approaches could enhance social acceptance and increase protection. (Source: AllAfrica News: HIV-Aids and STDs)
Warming Aids Arctic Economies But Far Short Of 'Cold Rush'
Climate change is aiding shipping, fisheries and tourism in the Arctic but the economic gains fall short of a &quot;cold rush&quot; for an icy region where temperatures are rising twice as fast as... -- Read more on ScientificAmerican.com (Source: Scientific American - Official RSS Feed)
California Trees Harbor Fungus Deadly to People with HIV
A 13-year-old's science fair project helped the discovery along, researchers say Source: HealthDay Related MedlinePlus Pages: Fungal Infections, HIV/AIDS and Infections (Source: MedlinePlus Health News)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Ghana: President Mahama Hopeful of HIV and Aids Elimination
[Ghana Govt.]President John Dramani Mahama last Friday said Ghana had the potential to reduce the incidence of HIV and AIDS new infections to zero per cent if proper regulations are adhered to. (Source: AllAfrica News: HIV-Aids and STDs)
Depression therapy aids other cancer symptoms
Conclusion Not surprisingly, this well-conducted study suggests that offering cancer patients with clinical depression an intensive, systematic treatment for depression involving all the people involved in their care, works better than the current approach. As the authors point out, the trial had some limitations. The sample was mainly women receiving follow-up or adjuvant treatment for breast and gynaecological cancers, so it is unclear whether the findings are generalisable to other cancer patients. Also, patients and their GPs could not be ?masked? as to whether they were in the DCPC group or the group receiving usual care, which might have influenced the findings. The striking results for patients in the DCPC group is probably attributable to treatment for depression being intens...
Kenya: Residents Urged to Accept Cut
[The Star]RESIDENTS of North Alego location, Bondo constituency have been urged to take up Voluntary Medical Male Circumcision as a preventive measure to fight HIV-Aids. (Source: AllAfrica News: HIV-Aids and STDs)
Zimbabwe: Woman Sticks By Man Who Infected Her With HIV
[The Herald]A Harare woman yesterday told the court that she would neither consent to advice to divorce nor accept a token of divorce from her husband because he infected her with HIV. (Source: AllAfrica News: HIV-Aids and STDs)
Kenya: HIV Groups in Kenyan Slum Organize Self-Help
[VOA]Nairobi -Kenyans living with HIV or AIDS in Kibera, Nairobi's largest slum, are finding support groups essential to coping with the health, economic and social challenges they face. (Source: AllAfrica News: Health and Medicine)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Uganda: HIV Prevention Act Angers Ugandan Aids Activists
[VOA]Kampala -Uganda's president recently signed the HIV and AIDS Prevention and Control Act into law. The bill criminalizes the transmission of HIV and also enforces mandatory testing. Such provisions have upset activists who want to de-stigmatize Uganda's HIV-positive community. (Source: AllAfrica News: Health and Medicine)
Sensory-tested drug-delivery vehicle could limit spread of HIV, AIDS
(Penn State) A unique method for delivering compounds that could positively impact the global battle against HIV and AIDS may be possible, thanks to researchers in Penn State's College of Agricultural Sciences. (Source: EurekAlert! - Medicine and Health)
New tool aids stem cell engineering for medical research
(Mayo Clinic) A Mayo Clinic researcher and his collaborators have developed an online analytic tool that will speed up and enhance the process of re-engineering cells for biomedical investigation. CellNet is a free-use Internet platform that uses network biology methods to aid stem cell engineering. Details of CellNet and its application to stem cell engineering are described in two back-to-back papers in the journal Cell. (Source: EurekAlert! - Biology)
54th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC)54th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC)
Read clinically focused news coverage of key developments from ICAAC 2014. Medscape Infectious Diseases (Source: Medscape Hiv-Aids Headlines)
Africa: Human Rights Must Be Central to HIV Prevention Efforts
[Key Correspondents]Last month, Australia hosted the 20th International AIDS Conference in Melbourne, putting HIV and human rights high on the agenda in discussions on the new post 2015 development goals. (Source: AllAfrica News: Health and Medicine)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
South Africa: U.S.-Sponsored Momconnect APP Provides Free Antenatal Information
[U.S. Embassy Pretoria]The U.S. Government, through the U.S. President's Emergency Plan for AIDS Relief (PEPFAR) program has invested $4.9 million (R49million) towards MomConnect, a program aimed at preventing maternal mortality through the use of mobile phone technology. (Source: AllAfrica News: Pregnancy and Childbirth)
Malawi: Gyan Arrives in the Country On Wednesday for HIV Prevention Campaign
[Malawi News Agency]Lilongwe -Renowned football ace, Asmoah Gyan who is also the team captain for the Ghana national side will arrive in the country today (Wednesday) evening as part of HIV Prevention Protect Goal campaign. (Source: AllAfrica News: HIV-Aids and STDs)
Malawi: President Mutharika to Sign Golden Ball Reaffirming Commitment to Prevent HIV
[Malawi News Agency]Lilongwe -State President Prof. Peter Mutharika will on Thursday sign a Golden Ball committing himself to HIV prevention. (Source: AllAfrica News: HIV-Aids and STDs)
Malawi: CYECE Empower Youths With SRH
[Malawi News Agency]Lilongwe -Promotion of sexual reproductive health, rights and HIV, enhancing youth empowerment and child rights and protection are some of the priority issues that have formed the backbone of the youth strategic plan that has been launched by Centre for Youth Empowerment and Civic Education (CYECE). (Source: AllAfrica News: HIV-Aids and STDs)
Nigeria: Ebola Overtakes HIV, Hepatitis As Health Concern
[Daily Trust]In the past month since Ebola landed in Nigeria, it has sped past major health issues to the topmost health concern for Nigerians, a new survey suggests. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Mervyn Susser, 92, Dies; Studied Illness and Society
Dr. Susser and his wife, Dr. Zena Stein, promoted some of the earliest educational and treatment programs for AIDS in South Africa. (Source: NYT Health)
Targeting Chemokine Receptor CXCR4 for Treatment of HIV-1 Infection, Tumor Progression, and Metastasis.
Authors: Choi WT, Yang Y, Xu Y, An J Abstract The chemokine receptor CXCR4 is required for the entry of human immunodeficiency virus type 1 (HIV-1) into target cells and for the development and dissemination of various types of cancers, including gastrointestinal, cutaneous, head and neck, pulmonary, gynecological, genitourinary, neurological, and hematological malignancies. The T-cell (T)-tropic HIV-1 strains use CXCR4 as the entry coreceptor; consequently, multiple CXCR4 antagonistic inhibitors have been developed for the treatment of acquired immune deficiency syndrome (AIDS). However, other potential applications of CXCR4 antagonists have become apparent since its discovery in 1996. In fact, increasing evidence demonstrates that epithelial and hematopoietic tumor cells exploit ...
Chemokine Receptor CCR5 Antagonist Maraviroc: Medicinal Chemistry and Clinical Applications.
Authors: Xu GG, Guo J, Wu Y Abstract The human immunodeficiency virus (HIV) causes acquired immumodeficiency syndrome (AIDS), one of the worst global pandemic. The virus infects human CD4 T cells and macrophages, and causes CD4 depletion. HIV enters target cells through the binding of the viral envelope glycoprotein to CD4 and the chemokine coreceptor, CXCR4 or CCR5. In particular, the CCR5-utilizing viruses predominate in the blood during the disease course. CCR5 is expressed on the surface of various immune cells including macrophages, monocytes, microglia, dendric cells, and active memory CD4 T cells. In the human population, the CCR5 genomic mutation, CCR5?32, is associated with relative resistance to HIV. These findings paved the way for the discovery and development of CCR5...
Maintenance of virologic efficacy and decrease in levels of ?2-microglobulin, soluble CD40L and soluble CD14 after switching previously treated HIV-infected patients to an NRTI-sparing dual therapy.
Authors: Romero-Sánchez MC, Alvarez-Ríos AI, Bernal-Morell E, Genebat M, Vera F, Benhnia MR, Bravo-Urbieta J, Galera-Peñaranda C, de Pablo-Bernal RS, Abad-Carrillo MA, Leal M, Ruiz-Mateos E, The VIH-GEMUVIH Región de Murcia Study Group Abstract Novel strategies are necessary to decrease inflammatory parameters in successfully treated HIV-infected patients. Our aim was to evaluate the maintenance of viral suppression and potential changes in inflammatory, immune-activation and coagulation biomarkers in virologically suppressed HIV-infected patients switched to a nucleoside reverse transcriptase inhibitor-sparing (NRTI) and maraviroc (MVC)-containing combined antiretroviral therapy (cART). Fifty-eight HIV-infected patients were observed after their treatment regimens were changed...
AIDS Progress in South Africa Is in Peril
Though few Americans realize it, South Africa owes much of its success in the fight against AIDS to a single United States program ? one that is now moving elsewhere. (Source: NYT)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Malawi: CCC Winds Up Its HIV Prevention Project in Mulanje
[Malawi News Agency]Mulanje -The Christian Community Church has this month wound up its Evidence Based Targeted HIV Prevention Project that was being implemented in Mulanje district. (Source: AllAfrica News: HIV-Aids and STDs)
Kenya: Awiti Teams to Fight Aids in Homa Bay
[The Star]AN inter-departmental committee will be formed in Homa Bay to coordinate HIV-Aids campaigns, Governor Cyprian Awiti has said. (Source: AllAfrica News: HIV-Aids and STDs)
Zambia: USAID Happy With Zambia's HIV/Aids Fight
[Times of Zambia]THE United States Agency for International Development (USAID) is elated with the strides Zambia has scored in the fight against HIV and AIDS. (Source: AllAfrica News: HIV-Aids and STDs)
Uganda: You Need More Than One Laboratory Test, Some Times
[Independent]Laura and Martin wanted to settle down together. They decided to do the necessary medical tests. That is when bad news struck; Laura was told she is HIV positive. (Source: AllAfrica News: HIV-Aids and STDs)
Zimbabwe: Fear-Struck Galz Holds On to HIV Research Data
[New Zimbabwe]THE Gays and Lesbians of Zimbabwe (GALZ) on Monday said they are holding on to research data on HIV prevalence among the gay community because of fear of victimisation by the government. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Kenya: Leaders Told to Spearhead HIV-Aids War
[The Star]ELECTED leaders from Luo Nyanza are to blame for the high HIV-Aids infections in the region, Uriri politician Paul Odhiambo has said. (Source: AllAfrica News: HIV-Aids and STDs)
Kenya: Kenya HIV Prevalence 4th Highest Globally
[New Times]Policy makers in the region are mulling several measures, including voluntary male circumcision, antiretroviral therapy, sustained behaviour change and condom distribution to fight HIV and other STIs. (Source: AllAfrica News: HIV-Aids and STDs)
In Vivo HIV-1 Hypermutation and Viral Loads Among Antiretroviral-Naive Brazilian Patients
AIDS Research and Human Retroviruses , Vol. 0, No. 0. (Source: AIDS Research and Human Retroviruses)
Adherence to highly active antiretroviral therapy and associated factors among children at the University of Gondar Hospital and Gondar Poly Clinic, Northwest Ethiopia: a cross-sectional institutional based study
Conclusion: Adherence rate to ART was found to be high. Disclosure of the child's HIV sero status to the child, the age of the child and the knowledge of the caregivers towards ART were factors associated with adherence. (Source: BMC Public Health - Latest articles)
Analysis of Special Education Policy in Turkey and United States: Improving Turkey's Policy for Students with Intellectual Disability
Abstract The authors compare the special education law of Turkey with comparable law of the United States. The basis of the comparison is the legal framework represented by the six principles of the special education law of the United States, the Individuals with Disabilities Education Act. Within each principle, the special implications for students with intellectual disability are noted. Suggestions for improving Turkey's special education law are made. These relate principally to the principles of zero reject and issues related to discipline; appropriate education, and issues concerning related services and supplementary aids and services; least restrictive environment as related specifically to students with intellectual disability; procedural due process and issues related to notice f...<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Safety status system for operating room devices.
CONCLUSIONS: The safety status system was suitable for an OR complex, both from a usability and technical point of view, and an increase of reported malfunctions was observed. The system eases monitoring the safety status of equipment and is a promising tool to improve the safety related to OR devices. PMID: 25159999 [PubMed - as supplied by publisher] (Source: Technology and Health Care)
[Media Watch] Public health on film
Few of us who grew up in Britain during the 1980s can have forgotten the famous tombstone public health film about AIDS. The image of a giant tombstone, blasting out of an apocalyptic landscape and chiselled with the word ?AIDS?, remains seared into the collective memory of a generation. First aired in 1987, the film presented AIDS as a deadly disease posing a threat to us all. With its dramatic funereal imagery, coupled with a doom-laden voiceover by the actor John Hurt, the film struck fear into the hearts of many. (Source: The Lancet Infectious Diseases)
[Media Watch] Living with HIV and dying with AIDS
The HIV pandemic has been the biggest threat to human health in recent history. This book examines two facets that lie at the heart of the HIV epidemic: first, the injustices and inequalities in relation to sex, race, sexuality, class, and geography; and second, the adverse social effect of HIV on individuals and their families, communities, and societies. (Source: The Lancet Infectious Diseases)
[Newsdesk] Highlights from the 20th International AIDS Conference
Likely to forevever be associated with the deaths of delegates on flight MH17, AIDS 2014 saw new targets for an end to AIDS and calls to combat discrimination. Peter Hayward reports. (Source: The Lancet Infectious Diseases)
[Comment] AIDS 2014?how the community responded to MH17
The news came through as we turned on our mobile phones, just minutes after the news of the MH17 plane crash broke. The circumstances of the crash were unknown at that time, and worried relatives had tried to contact many on our flight. We landed in Melbourne at 2am on a delayed Malaysian Airlines flight 129 from Kuala Lumpur. The same flight a day later should have carried several natives of the city and six delegates for the International AIDS Society's 2014 meeting who died when MH17 was shot down over eastern Ukraine. (Source: The Lancet Infectious Diseases)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
[Corrections] Corrections
Shah SK, Persaud D, Wendler DS, et al. Research into a functional cure for HIV in neonates: the need for ethical foresight. Lancet Infect Dis 2014; 14: 893?98?In this Personal View, the following funding information should have been added to the Acknowledgments section: ?Work on this manuscript by DP and HT was supported in part by the Johns Hopkins Center for AIDS Research, funded by the National Institutes of Health (grant number 1P30AI094189).? These changes have been made to the online version as of Aug 25, 2014. (Source: The Lancet Infectious Diseases)
Protein's ability to inhibit HIV release discovered
A family of proteins that promotes virus entry into cells also has the ability to block the release of HIV and other viruses, researchers have found. It is estimated that more than one million Americans currently are living with AIDS. AIDS is a condition characterized by progressive failure of the immune system. It is caused by the human immunodeficiency virus type 1 (HIV-1). (Source: ScienceDaily Headlines)
Three Approaches to Beating the AIDS Epidemic in South Africa
The pilot programs focus on subgroups like gay men, prostitutes, truckers, prisoners, miners and patients who don?t take their drugs regularly. (Source: NYT Health)
AIDS Progress in South Africa in Peril
Though few Americans realize it, South Africa owes much of its success in the fight against AIDS to a single United States program ? one that is now in moving elsewhere. (Source: NYT Health)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
AIDS Progress in South Africa Is in Peril
Though few Americans realize it, South Africa owes much of its success in the fight against AIDS to a single United States program ? one that is now moving elsewhere. (Source: NYT Health)
Hip hip, HARAA!
Click here to watch Team Haraa give us a hip hop low-down on their work: Hip Hip Haraa! 6 weeks in Haraa, it&#8217;s been real great Our team so safi, each other we don&#8217;t even hate We feel so karibu here, it&#8217;s home in our heart Hate to say baadae to our mamas and babas as we depart. We&#8217;ve been teaching in the school, the field, store fronts, to anyone who will listen 5 fluids, 4 doors, and 3 ways of transmission On testing day the people came out and our goals we bested, For the only way to know your status is to get tested People dragged out their friends, the whole event was quite grand, The future of Haraa was in their hand Supporting each other even when results were feared, Tuko Pamoja Kuushinda UKIMWI, together we cheered! We taught a bunch, but learned even more,...
Pre-Exposure Prophylaxis and Contraception EffectivenessPre-Exposure Prophylaxis and Contraception Effectiveness
How effective are hormonal contraceptives for pregnancy prevention in women taking HIV pre-exposure prophylaxis? AIDS (Source: Medscape Today Headlines)
Raltegravir in Virologically Suppressed Overweight WomenRaltegravir in Virologically Suppressed Overweight Women
When women with central adiposity switch to RAL from a PI or NNRTI, they could experience a significant decrease in sCD14. HIV Medicine (Source: Medscape Today Headlines)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Kenya: Circumcision Secretariat Closes
[The Star]The secretariat that coordinated all voluntary medical male circumcision in Kenya the last six years has closed. (Source: AllAfrica News: HIV-Aids and STDs)
Kenya: Govt Weary of Public Response to HIV and Aids Scourge
[The Star]Although HIV and Aids have highly been demystified, the government is warning of dire consequences if the current behavioural trend continue. (Source: AllAfrica News: HIV-Aids and STDs)
Kenya: Join Fight On HIV-Aids, Awiti Tells Leaders
[The Star]HOMA BAY Governor Cyprian Awiti has decried the high rate of HIV-Aids infection in the county. (Source: AllAfrica News: HIV-Aids and STDs)
Zambia: Chief Chikanta Launches Policy to Combat HIV/Aids
[Times of Zambia]CHIEF Chikanta and his subjects in Kalomo District have launched a leadership declaration to commit to combat HIVAIDS in a comprehensive manner. (Source: AllAfrica News: HIV-Aids and STDs)
Kenya: Kenya Launches HIV Prevention Road Map
[Sabahi]The Kenyan government on Wednesday (August 20th) launched a new HIV prevention programme in an effort to achieve "zero new HIV infections in Kenya", United Nations AIDS announced. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Zambia: Chikanta HIV/Aids Policy a Milestone
[Times of Zambia]WITH the cure for HIV/AIDS still elusive, it is clear that the fight against the pandemic cannot be restricted to one group but all the people have a role to play in stopping it. (Source: AllAfrica News: HIV-Aids and STDs)
Tanzania: Mkapa Foundation Hailed for Complementing Govt Efforts
[Daily News]Mwanza -THE government has commended the Benjamin Mkapa HIV-AIDS Foundation for its dedication and support in complementing the country's health initiatives by reaching the underserved members of the society. (Source: AllAfrica News: HIV-Aids and STDs)
Zimbabwe: Condoms Used to Ease Arthritis Pain
[Zimbabwe Standard]Free condoms distributed in the country to reduce the spread of HIV and Aids have found an unexpected user in Zimbabwe - they are now being use to "treat" arthritis. (Source: AllAfrica News: Health and Medicine)
The development of simple anthropometric measures to diagnose antiretroviral therapy-associated lipodystrophy in resource limited settings.
CONCLUSIONS: We were able to develop simple, anthropometric measures for defining lipoatrophy and lipohypertrophy, using a sample of black HIV-infected South African women with DXA scans. This is of particular relevance in resource limited settings, where health professionals need simple and inexpensive methods of diagnosing patients with lipoatrophy and lipohypertrophy. PMID: 25143778 [PubMed] (Source: AIDS Research and Therapy)
Editorial: Impact of Alcohol on HIV Related Issues in Human Population or Model System.
Authors: Kumar A Abstract Alcohol abuse and AIDS remain two of the leading public health problems, not only in the United States but throughout the world. Approximately amongst 5% of the total US population, abuses alcohol and this statistic has been fairly consistent during recent years. However, the prevalence of alcohol abuse among HIV-positive individuals has been estimated to be between 29 and 60% in the US [1]. Alcohol use has also been implicated as an important risk factor in HIV transmission. In addition, the incidence of HIV infection has been found to be associated with the overall level of alcohol consumption. In a meta-analysis study, drinkers were found to be at a 77% higher risk of HIV-infection than non-drinkers [2]. In another meta-analysis of studies conducted in ...<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Oncogenic viruses associated with vulva cancer in HIV-1 patients in Botswana
Conclusion: Our study, suggests that in Botswana, vulvar squamous cell carcinoma (VSCC) is associated with oncogenic viruses present in the niche but the contribution and progression may be regulated by HPV and other immunosuppressive infections that include HIV-1. (Source: Epidemiologic Perspectives and Innovations)
Communicating with disabled children when inpatients: barriers and facilitators identified by parents and professionals in a qualitative study
ConclusionsCommunication with disabled children on the ward was perceived as less than optimal. Parents are instrumental in the communication between their children and professionals. Although aware of the importance of communication with disabled children, staff perceived time pressures and lack of priority given to communicating directly with the child as major barriers. (Source: Health Expectations)
Noted Epidemiologist and Former FDA Deputy Director Janet B....
NDA Partners announced today that Janet B. Arrowsmith, MD, a noted expert in epidemiology and internal medicine and former Deputy Director, Office of AIDS and Special Health Concerns, Office of the...(PRWeb August 23, 2014)Read the full story at http://www.prweb.com/releases/2014/08/prweb12112164.htm (Source: PRWeb: Medical Pharmaceuticals)
Zimbabwe: I Want My Foreskin Back!
[The Herald]Debate is raging across African countries, Zimbabwe included on what happens to men's foreskins following circumcision. (Source: AllAfrica News: HIV-Aids and STDs)
Sustained favourable HIV viral load response in South African patients during concomitant HAART and cancer therapy
HIV infection has led to an increase of both AIDS defining and non?AIDS defining cancers. Immunosuppressive cancer therapy had been noted for increased HIV viral load in cancer patients infected with HIV before the advent of highly active antiretroviral therapy (HAART). Assessing the outcome of concomitant HAART and cancer treatment in regions endemic for HIV is thus important. From a cohort of 34 cancer patients infected with HIV, 10 (six underwent radiotherapy and four chemotherapy) had at least three serial samples collected before, during and after treatment. From each sample, HIV viral load, CD4?+? and CD8?+? cell count was investigated. HIV genotypic drug resistance was assessed for six patients with a detectable HIV viral load at baseline. Of the 10 patients; one was HIV p...<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Family Economic Strengthening and Parenting Stress Among Caregivers of AIDS-Orphaned Children: Results from a Cluster Randomized Clinical Trial in Uganda.
This study examines the impact of a family economic strengthening intervention on parenting stress among caregivers of AIDS-orphaned children in Uganda. The study uses data from a 4-year (2008-2012) NIMH randomized clinical trial for AIDS-orphaned children known as Suubi-Maka (N=346 dyads). Child-caregiver dyads from 10 comparable primary schools were randomly assigned to either the control group (n=167 dyads) receiving usual care for school-going orphaned children (such as food aid and scholastic materials) or the treatment group (n=179 dyads) receiving a family economic strengthening intervention (focused on a matched savings account), financial planning and management workshops over and above the usual care. Interviews were conducted at baseline, 12 months and 24 months follow-up. This ...
[Comment] The end of AIDS and the NGO Code of Conduct
Country ownership and health-system strengthening are key global health slogans in the current era of HIV/AIDS treatment scale-up. Their meaning, however, is hotly debated. Is country ownership equivalent to government ownership? Which health system should be strengthened?health care delivered by non-governmental organisations (NGOs), the public sector, private for-profit organisations, or some combination of these actors? Although breakthroughs in HIV treatment have provoked rallying cries for an ?AIDS-free generation? and the ?end of AIDS?, these calls clash with the reality of understaffed public health systems across Africa that struggle to manage their current patient load, let alone the millions of additional patients who require treatment under new WHO HIV treatment guidel...
HIV infection, bone metabolism, and fractures
With the advent of high active antiretroviral therapy there was a significant improvement on HIV subjects survival. Thus, bone changes related to HIV became an important aspect of these individuals. HIV affects bone remodeling causing bone fragility. In addition, antiretroviral therapy may also negatively affect bone metabolism. Several studies describe an increased incidence of fractures in these patients when compared with controls without the disease. The European Society of AIDS (EACS), and other societies, have included guidance on management of osteoporosis in HIV-infected patients emphasizing the identification of patients with low bone mass. Supplementation of calcium and vitamin D and the use of alendronate in these individuals should be recommended on a case base.Com o advento da...
FDA OKs New Triple-Combination Pill (Triumeq) for HIV FDA OKs New Triple-Combination Pill (Triumeq) for HIV
Triumeq is the first once-daily fixed-dose triple-combination pill to include dolutegravir. Its components were found superior to currently used single-pill therapy in a previous phase 3 trial. FDA Approvals (Source: Medscape Medical News Headlines)
Botswana: Court Orders Free HIV Meds for Foreign Prisoners
[SALC]Gaborone -Today, the Botswana High Court ordered the government to provide anti-retroviral (ARV) treatment to HIV-positive, foreign prisoners at state expense. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Linker Helps Detect Protein Partners
Biochemistry: Cleavable photo-cross-linker aids protein-protein interaction analysis (Source: Chemical and Engineering News)
Kenya: First Lady Alarmed By High HIV Prevalence in Samburu County
[The Star]First Lady Margaret Kenyatta arrives in Maralal for the official handing over of the 3rd Beyond Zero mobile clinic to Samburu County officials. Photo/PSCU (Source: AllAfrica News: HIV-Aids and STDs)
Fungus deadly to AIDS patients found to grow on trees
Researchers have pinpointed the environmental source of fungal infections that have been sickening HIV/AIDS patients in Southern California for decades. It literally grows on trees. The discovery is based on the science project of a 13-year-old girl, who spent the summer gathering soil and tree samples from areas around Los Angeles hardest hit by infections of the fungus named Cryptococcus gattii (CRIP-to-cock-us GAT-ee-eye). (Source: ScienceDaily Headlines)
Tanzania: Mkapa Foundation On HIV/Aids Focuses On 15 Districts
[Daily News]THE Benjamin William Mkapa HIV/AIDS Foundation (BMAF) through its Mkapa Fellows Project is targeting to improve HIV/AIDS and Tuberculosis health service delivery to fifteen districts in Rukwa, Shinyanga, Simiyu, Kagera and Zanzibar . (Source: AllAfrica News: HIV-Aids and STDs)
Zimbabwe: Condom Use Up
[The Herald]The use of condoms increased by 22 percent in the past two decades owing largely to behavioural change, says Population Services International. PSI country director Mrs Louisa Norman said the increase in condom use had contributed to the decline in HIV prevalence rate. She was speaking at the launch of the new protector plus condom "New Man" by Health and Child care Minister Dr David Parirenyatwa in Harare on Wednesday. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Uganda: HIV Law - President Museveni Under Fire
[Observer]Even after the presidential assent, health rights civil society organisations want amendments to the contentious provisions in the 2014 HIV Prevention and Control Act. (Source: AllAfrica News: HIV-Aids and STDs)
Brain Magnetic Resonance Imaging Screening Is Not Useful for HIV-1-Infected Patients Without Neurological Symptoms
AIDS Research and Human Retroviruses , Vol. 0, No. 0. (Source: AIDS Research and Human Retroviruses)
[Perspective] Joep Lange (1954?2014)
A leader in developing therapy for AIDS is tragically killed Author: Jaap Goudsmit (Source: Science: Current Issue)
Functional response of the small multidrug resistance protein EmrE to mutations in transmembrane helix 2
Widespread use of antimicrobials has resulted in the emergence of nosocomial pathogens such as methicillin resistant Staphylococcus aureus (MRSA, [1]), an organism that causes more deaths among U.S. hospital patients than HIV/AIDS and tuberculosis combined [2]. Persistence of MRSA strains is linked to multidrug efflux transporters of the small multidrug resistance (SMR) family [3,4]. Indeed, the first SMR identified, Smr/QacC, was isolated from clinical S. aureus resistant to cationic disinfectants and antiseptics (termed biocides) [5]. (Source: FEBS Letters)
A new prognostic score for AIDS-related lymphomas in the Rituximab-era.
We examined the association of HIV-related and other known risk factors with overall survival in both sets independently. We defined a new score (AIDS-related lymphoma International Prognostic Index) by assigning weights to each significant predictor (age-adjusted international prognostic index, extranodal sites, HIV-score [composed of CD4 count, viral load, and prior history of AIDS]) with three risk categories similar to the age-adjusted International Prognostic Index (low, intermediate and high risk). We compared the prognostic value for overall survival between AIDS-related lymphoma International Prognostic Index and age-adjusted International Prognostic Index in the validation set and found that the AIDS-related lymphoma International Prognostic Index performed significantly better in...<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Vault nanoparticles engineered at UCLA show promise for cancer treatment and possible HIV cure
American Chemical Society UCLA scientists developed a method for placing bryostatin 1 in nanoscale vaults for safe delivery to cells, where it can activate latent HIV, enabling the virus to be eradicated. A multidisciplinary team of scientists from UCLA and Stanford University has used a naturally occurring nanoparticle called a vault to create a novel drug delivery system that could lead to advances in the treatment of cancer and HIV. The research team was led by Dr. Leonard Rome, associate director of UCLA?s California NanoSystems Institute, and Dr. Jerome Zack, co-director of the UCLA AIDS Institute, both of whom are also members of UCLA?s Jonsson Comprehensive Cancer Center. Co-first authors on the study were Daniel Buehler, a UCLA postdoctoral researcher and Matthew Marsden, adju...
HIV/HBV CoinfectionHIV/HBV Coinfection
This guideline from the New York State Department of Health offers guidance to clinicians for vaccination, treatment, and monitoring of hepatitis B infections in HIV-infected patients. Medscape HIV/AIDS (Source: Medscape Hiv-Aids Headlines)
South Africa: Presentations - South Africa's HIV, TB Investment Case
[Health-e]Experts' presentations on South Africa's HIV "investment case" made at a July consultation organised by the country's national AIDS council. (Source: AllAfrica News: HIV-Aids and STDs)
Uganda: Controversial HIV Bill Signed Into Law
[IPS]Kampala -HIV/AIDS activists are adamant Uganda will not achieve an "AIDS-free generation" now a "backwards" HIV/AIDS Bill criminalising the "wilful and intentional" transmission of the disease has been signed into law. (Source: AllAfrica News: Health and Medicine)
Nigeria: Ondo Intensifies Fight Against HIV/Aids
[Daily Independent]Ondo State Agency for the Control of AIDS (ODSACA) has commenced training on Minimum Prevention Intervention Packages and District Head Information System (MPIP/DHIS) for Civil Society Organisations, Executive Directors, Line Ministries Focal persons, Monitoring and Evaluation Officers of State Action Committee on AIDS and Service Support Organisations. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Zambia: PMTCT Real Life Story
[Times of Zambia]THE pain of living through the loss of three children, was enough to discourage Constance Mudenda from ever contemplating parenting! (Source: AllAfrica News: HIV-Aids and STDs)
Fungus deadly to AIDS patients found to grow on trees
(Duke University) Researchers have pinpointed the environmental source of fungal infections that have been sickening HIV/AIDS patients in Southern California for decades. It literally grows on trees. (Source: EurekAlert! - Medicine and Health)
Phylogenetic and Temporal Dynamics of Human Immunodeficiency Virus Type 1B in China: Four Types of B Strains Circulate in China
AIDS Research and Human Retroviruses , Vol. 0, No. 0. (Source: AIDS Research and Human Retroviruses)
Shunt malfunction presenting with symptomatic syringomyelia: Demonstrated on contrast ventriculogram
We report a case of chronic tuberculous meningitis with shunt malfunction presenting as an expanding spinal canal syrinx and quadriparesis. Fourth ventricular communication with syrinx was demonstrated with the help of a contrast ventriculogram. After shunt revision, syrinx resolved completely and the patient made significant improvement in his neurological deficits. The present case illustrates that a historical and rarely used investigation like contrast ventriculogram aids in the diagnosis and management even in the current neurosurgical practice. All patients with late onset syrinx and a previous VP shunt need to be investigated for shunt malfunction before considering syrinx surgery. A simple shunt revision resolves the syrinx in such conditions and avoids more complex procedures like...
Highlights from the 2014 International Symposium on HIV & Emerging Infectious Diseases (ISHEID): from cART management to the end of the HIV pandemic
In this report we not only give details on this main topic but also summarize what has been discussed in the areas of HCV coinfection and present a short summary on currently emerging viral diseases. (Source: AIDS Research and Therapy)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Unusual Presentation of Visceral Leishmaniasis in an HIV-Infected Patient
AIDS Research and Human Retroviruses , Vol. 0, No. 0. (Source: AIDS Research and Human Retroviruses)
Malawi: Kapito Condemns ARV Misuse
[Malawi News Agency]Blantyre -Renowned human rights activist and Consumer Association of Malawi (CAMA) Executive Director, John Kapito has described the misuse of antiretroviral drugs (ARVs) recently reported in the media as disappointing. (Source: AllAfrica News: HIV-Aids and STDs)
Zimbabwe: Zimbabwean Government Takes Action Against Increasing Rape
[Key Correspondents]Every year, more than 3,000 young girls are raped in Zimbabwe - often by members of their own families. With the number of cases increasing, Zimbabwe's government has launched a national campaign to tackle the issue, which is causing great trauma and new HIV infections. (Source: AllAfrica News: HIV-Aids and STDs)
Kenya: Cultural Practices Blamed for HIV-Aids Spread
[The Star]OUTDATED cxultural practices are to blame for the spread of HIV-Aids among the Luo community, an NGO has said. (Source: AllAfrica News: HIV-Aids and STDs)
Kenya: In Rural Kenya, Pressure Builds Against Female Circumcision
[VOA]It's the last day of school in Tharaka-Nithi, a community in Kenya's remote former Eastern province. Classrooms are empty, signaling the start of a one-month break for students. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
[Pneumocystis pneumonia in HIV-infected patients with cytomegalovirus co-infection. Two case reports and a literature review].
Authors: Polaczek MM, Zych J, Oniszh K, Szopi?ski J, Grudny J, Roszkowski-?li? K Abstract Pneumocystis pneumonia (PCP) is one of the infectious lung diseases diagnosed in HIV-infected patients. The pathogen responsible for the development of this opportunistic infection is an atypical fungus called Pneumocystis jiroveci. PCP remains the most common disorder diagnosed at the onset of acquired immunodeficiency syndrome (AIDS), especially in individuals not aware of their HIV infection. The most important risk factor of PCP development in HIV-infected person is the decrease of T CD4+ cell number below 200/mcL. Clinical symptoms consist of: chronic cough, dyspnoea and weakness. Arterial blood gas analysis often reveals the presence of hypoxaemia, and high-resolution computed tomogra...
Uganda: Uganda On Track With Paediatric HIV Control
[Observer]Once, while visiting Baylor College of Medicine in Mulago, I was welcomed by a group of 15 children, happily swaying to the melody of their song. (Source: AllAfrica News: HIV-Aids and STDs)
Zimbabwe: 'Mining Communities At Risk of Contracting TB'
[The Herald]People working and living in mining communities could be six times more at risk of contracting tuberculosis than those in other occupations, Government has said. Deputy director of Aids and Tuberculosis in the Ministry of Health and Child Care, Dr Charles Sandy, said the statistics were based on trends coming from other countries such as South Africa, Botswana and those of Zimbabwe. (Source: AllAfrica News: Tuberculosis)
The agnoprotein of polyomavirus JC is released by infected cells: Evidence for Its cellular uptake by uninfected neighboring cells.
Authors: Otlu O, De Simone FI, Otalora YL, Khalili K, Sariyer IK Abstract Poliomavirus JC replicates in glial cells in the brain, and causes the fatal demyelinating disease, progressive multifocal leukoencephalopathy (PML). PML is usually seen in patients with underlying immunocompromised conditions, notably among AIDS patients and those on chronic immunosuppressive regimens. The late leader sequence of JC virus contains an open reading frame encoding a small regulatory protein called agnoprotein. Agnoprotein contributes to progressive viral infection by playing significant roles in viral replication cycle. Here, we demonstrate that agnoprotein can be detected in cell-free fractions of glial cultures infected with JCV, transfected with expression plasmids or transduced with an aden...
Utility of nine-color, 11-parameter flow cytometry for detection of plasma cell neoplasms: a comparison with bone marrow morphologic findings and concurrent m-protein studies in serum and urine.
CONCLUSIONS: The nine-color analytic cocktail eliminates duplication of PC gating reagents required for evaluation of the same epitopes using a five- or six-color approach. Fewer analytic cocktails result in lower instrument acquisition times per case, a significant factor for the large data sets required for optimal residual disease assessment. Finally, concurrent analysis of nine epitopes and two light scatter parameters aids detection of residual disease, particularly when it is mixed with polyclonal PCs. PMID: 25125632 [PubMed - in process] (Source: American Journal of Clinical Pathology)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
New vaccine shows promise as stronger weapon against both tuberculosis and leprosy
In many parts of the world, leprosy and tuberculosis live side-by-side. Worldwide there are approximately 233,000 new cases of leprosy per year, with nearly all of them occurring where tuberculosis is endemic. The currently available century-old vaccine Bacille Calmette-Guerin, or BCG, provides only partial protection against both tuberculosis and leprosy, so a more potent vaccine is needed to combat both diseases. UCLA-led research may have found a stronger weapon against both diseases. In a study published in the September issue of the peer-reviewed journal Infection and Immunity, the researchers found that rBCG30, a recombinant variant of BCG that overexpresses a highly abundant 30 kDa protein of the tuberculosis bacterium known as Antigen 85B, is superior to BCG in protecting against t...
HIV and Hepatitis C Risk in Pregnancy and Newborns
Infection with HIV or Hepatitis C is especially prevalent in pregnant women with a history of drug and alcohol use. Although newborn infection rates are becoming less common, this remains an issue of vital importance for prospective adoptive parents.read more (Source: Psychology Today Parenting Center)
Hello again from Nduruma!
Hello again from VP3! It?s been a while since we last checked in, and we?ve been up to a lot here in Nduruma. We?ve added a steady stream of community teachings to the schedule, and are now familiar faces at all of the schools in the ward. We?ve kicked off our district-wide soccer tournament with a hard fought game between the mzungus and the Mzimuni team, and we are also busy planning community day and a few more testing days. Soon we will add getting nostalgic about our time here in Nduruma to our list of activities. Upon some reflection fueled by chipsi mayai, we?ve come to realize we?ve all grown in different ways during our time in village. This blog will attempt to highlight this growth, starting with Ben. Besides the very literal growth of Ben?s luxurious hair, groomed...
Namibia: More and More Men Accept Being Circumcised
[New Era]Katima Mulilo -New statistics from the World Health Organisation (WHO) indicated an estimated 5.8 million males in 14 African priority countries have undergone circumcision over the past five years. (Source: AllAfrica News: HIV-Aids and STDs)
South Africa: Red Cross Dispel Sex Workers Myths in HIV Education
[IFRC]When MG first arrived in the dusty transit town of Musina, northern South Africa - fleeing from the fighting Zimbabwe in 2008 - as an undocumented worker, she started off doing odd jobs. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Africa: People Who Use Drugs Left Behind By Global Funding Gap
[Key Correspondents]The fight to defeat HIV among those most at risk of infection may not be achieved as soon as hoped unless harm reduction services for people who use drugs receive appropriate funding. (Source: AllAfrica News: HIV-Aids and STDs)
Uganda: Helping HIV Positive Women Avoid Unplanned Pregnancies
[IPS]Barbara Kemigisa used to call herself an "HIV/AIDS campaigner". These days she would rather be known as an "HIV/AIDS family planning campaigner". (Source: AllAfrica News: HIV-Aids and STDs)
South Africa: Love, Suspicion and HIV Discordancy
[Health-e]Sindi Letlala* and her 3-year-old son Thato are HIV positive. Sindi's husband of 12 years and Thato's father, Thabiso, is not. She talks to OurHealth about dealing with discordancy. (Source: AllAfrica News: HIV-Aids and STDs)
Therapeutic drug monitoring of voriconazole: a case report of multiple drug interactions in a patient with an increased CYP2C19 activity.
CONCLUSION: The integration of drug-drug interactions and pharmacogenetics data is crucial to interpret drug concentrations correctly, thus preventing suboptimal exposure to voriconazole. PMID: 25120580 [PubMed] (Source: AIDS Research and Therapy)
Influence of providers and nurses on completion of non-targeted HIV screening in an urgent care setting.
CONCLUSIONS: Visit provider and triage nurse were strongly associated with acceptance of testing, which may reflect variable opinions of HIV screening in this setting by clinical staff. Among patients accepting screening, visit provider remained strongly associated with completion of testing. Despite longstanding recommendations for non-targeted HIV screening, further changes to improve the testing and results process, as well as provider education and buy-in, are needed to improve screening rates. PMID: 25120579 [PubMed] (Source: AIDS Research and Therapy)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Differential glycosylation of envelope gp120 is associated with differential recognition of HIV-1 by virus-specific antibodies and cell infection.
CONCLUSION: Our data support the hypothesis that the glycosylation machinery of different cells shapes gp120 glycosylation and, consequently, impacts envelope recognition by specific antibodies as well as the interaction of HIV-1 gp120 with cellular receptors. These findings underscore the importance of selection of appropriately glycosylated HIV-1 envelope as a vaccine antigen. PMID: 25120578 [PubMed] (Source: AIDS Research and Therapy)
Results from a Secondary Data Analysis Regarding Satisfaction with Health Care among African American Women Living with HIV/AIDS
ConclusionBecause satisfaction with health care can influence the quality of care received, health outcomes, and adherence to provider recommendations among patients living with HIV/AIDS, health care providers? ability to elicit satisfaction from their patients is just as important as the services they provide. This project is one of the first studies to find high rates of satisfaction with health care among African American women living with HIV/AIDS. Further examination of satisfaction with health care among African American women living HIV/AIDS may help in narrowing health care disparities and negative treatment outcomes. (Source: Journal of Obstetric, Gynecologic, and Neonatal Nursing)
A Multilevel Understanding of HIV/AIDS Disease Burden Among African American Women
ABSTRACT Disproportionate HIV/AIDS rates among African American women have been examined extensively, primarily from an individual?centered focus. Beyond individual behaviors, factors such as the hyperincarceration of African American men and geographically concentrated disadvantage may better explain inequitable disease burden. In this article I propose a conceptual model of individual, social, and structural factors that influence HIV transmission among African American women. The model can be used to develop comprehensive assessments and guide prevention programs in African American communities. (Source: Journal of Obstetric, Gynecologic, and Neonatal Nursing)
Evidence-based risk communication: a systematic review.
CONCLUSION: Visual aids and absolute risk formats can improve patients' understanding of probabilistic information, whereas numbers needed to treat can lessen their understanding. Due to study heterogeneity, the superiority of any single method for conveying probabilistic information is not established, but there are several good options to help clinicians communicate with patients. PRIMARY FUNDING SOURCE: None. PMID: 25133362 [PubMed - in process] (Source: Annals of Internal Medicine)
Sexually Transmitted Infection Related Stigma and Shame Among African American Male Youth: Implications for Testing Practices, Partner Notification, and Treatment
AIDS Patient Care and STDs Sep 2014, Vol. 28, No. 9: 499-506. (Source: AIDS Patient Care and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Nonoccupational Postexposure Prophylaxis for HIV PreventionNonoccupational Postexposure Prophylaxis for HIV Prevention
There have been many challenges with the implementation of HIV nonoccupational postexposure prophylaxis. What new solutions are on the horizon? AIDS (Source: Medscape Today Headlines)
Helping Uganda?s HIV positive Women Avoid Unplanned Pregnancies
Contraception is a smart choice but HIV positive women have to jump through the hooks to get it. Credit: Amy Fallon/IPSBy Amy FallonKAMPALA, Aug 18 2014 (IPS) Barbara Kemigisa used to call herself an ?HIV/AIDS campaigner?. These days she would rather be known as an ?HIV/AIDS family planning campaigner?. ?We need to reduce unplanned pregnancies and the HIV infection rate in our country,? Kemigisa told IPS during Uganda?s first national family planning conference on July 28. ?It?s about dual protection.? Raped by two uncles from an early age, Kemigisa later became promiscuous. When she was 22, she discovered she was HIV positive &#8211; and two months pregnant. Her daughter, Kourtney, now five, was born negative. But the mother couldn?t afford to buy her formula milk a...
Rwanda: HIV, TB, Malaria Deaths Decline
[New Times]The world's most infectious diseases-HIV/AIDS, tuberculosis and malaria-are losing ground as a result of growing efforts to mobilise resources to combat them. (Source: AllAfrica News: HIV-Aids and STDs)
Nigeria: Pathetic - How a Movie Star Contracted HIV in the Church
[Vanguard]Her story runs like a novel, yet it is no fiction. It underscores the saying 'misfortunes bring out the best in a person." (Source: AllAfrica News: HIV-Aids and STDs)
Africa: Global Fund Offering Technical Assistance On Community, Rights and Gender
[GFO]Communities and civil society can now receive support from the Global Fund for activities addressing community, rights and gender challenges (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Sudan: Sudan Submits Consolidated Concept Note
[GFO]All three disease components plus health system strengthening included in single pitch (Source: AllAfrica News: HIV-Aids and STDs)
Africa: Pushing the Envelope - Will the Global Fund's New Funding Model Foster Country Ambitions?
[GFO]The new funding model (NFM) is the crucial opportunity to determine the speed with which countries are able to expand and innovate in their responses to the three diseases and to make up for delays in the scale-up of programs that has been stalled since the cancellation of Round 11. (Source: AllAfrica News: HIV-Aids and STDs)
Africa: Workshop Participants Urge the Global Fund to Review Its Policies On Human Rights
[GFO]Concept notes should address structural barriers (Source: AllAfrica News: HIV-Aids and STDs)
Africa: The Weakest Link of HIV Prevention in Africa - Contraception
[IPS]Nairobi -In the rush to save babies from HIV infection and treat their mothers, experts warn that a key element of HIV prevention is being neglected in Africa - contraceptives for HIV positive women. (Source: AllAfrica News: HIV-Aids and STDs)
Nigeria: She Infected Me With HIV, Dated Other Men - Suspected Wife Killer
[Daily Independent]Lagos -A suspect, Katongu Philip, is currently cooling his heels at the cells of the Criminal Investigations Department (CID) of the Lagos State Police Command, Yaba, over the murder of a lady, Justina James, said to be his wife. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Zambia: Remembering Dr Khama the K-Punch HIV/Aids Drug Pioneer
[Times of Zambia]Would you believe it - you are sick and decide to go and see your doctor at the local surgery only to be told the surgery is no longer functioning because the doctor died several months ago? (Source: AllAfrica News: HIV-Aids and STDs)
Angola: Asa Branca Market With Mobile Clinic for HIV/Aids Blood Test
[ANGOP]Luanda -A mobile clinic for voluntary HIV/Aids blood test and the holding of a family planning is available since Thursday in Asa-Branca market in Cazenga municipality in Luanda in order to deal with vendors and other citizens. (Source: AllAfrica News: HIV-Aids and STDs)
Ethiopia: 'Triple Jeopardy' - the Struggle of the Little Ones
[Reporter]Scattered around the infamous currency black market area (the self-proclaimed forex bureaus) of Addis Ababa - areas including Ambassador Theater and Ethiopia Hotel - young men importune passersby, especially those who, they suspect had come from abroad. (Source: AllAfrica News: HIV-Aids and STDs)
Ethiopia: Helping Men Take Responsibility for Ending Aids
[Reporter]Transformative change is afoot among men and boys throughout southern and eastern Africa. Millions have bravely stepped up to protect themselves and their partners from HIV. (Source: AllAfrica News: Health and Medicine)
AIDS, loss and renewal.
Authors: Kirby TH PMID: 25164845 [PubMed - in process] (Source: Med J Aust)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Prevalence of Voluntary Counseling and Testing Utilization and Its Associated Factors among Bahirdar University Students.
Conclusion. The major factors identified for increased VCT service utilization were having a friend who got VCT, having discussion about HIV/AIDS with family, origin of residence, year of study, and having boy- or girlfriend. Therefore, actions targeting these predictors are necessary to effectively enhance the use of the VCT services utilization among students. PMID: 25105028 [PubMed] (Source: Adv Data)
AIDS 2014: Intermittent and 'On-Demand' PrEPAIDS 2014: Intermittent and 'On-Demand' PrEP
Dr. Paul Sax looks at 2 studies from AIDS 2014: the open-label extension of the iPrEx study, and the IPERGAY trial. Medscape HIV/AIDS (Source: Medscape Hiv-Aids Headlines)
West Africa: 5 Things to Do Right Now about Ebola
[AIDS Free World]It's very difficult to know what to say about the Ebola outbreak. Let me take a crack at it: (Source: AllAfrica News: Health and Medicine)
Developing self-sustainable hearing centers in the developing world - case study of EARs Inc project in Dominican Republic.
CONCLUSIONS: The development of comprehensive diagnostic and rehabilitation services requires equipping and training local staff. Implications for Rehabilitation A good hearing aid fitting is more than technology - patient education and the clinician fitting the hearing aid are important. Access to follow-up services including battery supplies, hearing aid adjustments and hearing aid repairs is essential to any hearing aid fitting program in low and middle income countries. Check the WHO guidelines for hearing aid provision in developing countries when planning a program. When working in a country co-ordinate with local professional involved in hearing health where available. PMID: 25119293 [PubMed - in process] (Source: Disability and Rehabilitation. Assistive Technology.)
Namibia: Govt to Introduce Single Dose HIV Drug
[New Era]Oshakati -The Ministry of Health and Social Services is on the verge of phasing out multiple tablet anti-retroviral (ARV) dosage to a single tablet dose per day. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Liberia: 'No Time for Politics' - Says Christopher Neyor As He Aids Anti-Ebola Efforts
[New Republic]The Chief Executive officer (CEO) of MOWEH Energy, Mr. Christopher Neyor, has said the troubling consequences of the Ebola virus have presented the need for all Liberians to stand together, regardless of politics or where one comes from, in combating getting rid of it. (Source: AllAfrica News: Health and Medicine)
Kenya: Residents Told to Go for HIV Tests
[The Star]Bungoma Governor Kenneth Lusaka's wife, Margaret Makelo, has asked county residents to go for HIV tests. (Source: AllAfrica News: HIV-Aids and STDs)
Africa: What's More Important, the War On Aids or Just War?
[IPS]Johannesburg/New York -They say there is a war on and its target is the deadly human immunodeficiency virus (HIV). This war runs worldwide but its main battleground is sub-Saharan Africa, where seven out of 10 HIV positive persons in the world live - 24.7 million in 2013. The region suffered up to 1.3 million AIDS-related deaths in the same year, according to the United Nations. (Source: AllAfrica News: HIV-Aids and STDs)
Rwanda: Editor's Note
[New Times]Dear readers (Source: AllAfrica News: HIV-Aids and STDs)
Rwanda: Helping Men Take Responsibility to End HIV/Aids
[New Times]Transformative change is afoot among men and boys throughout eastern and southern Africa. Millions have bravely stepped up to protect themselves and their partners from HIV. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Malawi: People Living With HIV Petition Ntcheu District Commissioner
[Malawi News Agency]Ntcheu -Following a two day workshop for people living with HIV and AIDS which was organized by Malawi Interfaith Aids Association in corroboration with Ntcheu District Interfaith Aids Committee, participants to the workshop Tuesday presented a petition which contained some of the challenges which people living with HIV face to Ntcheu District Commissioner. (Source: AllAfrica News: HIV-Aids and STDs)
Sequence-Conserved and Antibody-Accessible Sites in the V1V2 Domain of HIV-1 gp120 Envelope Protein
AIDS Research and Human Retroviruses , Vol. 0, No. 0. (Source: AIDS Research and Human Retroviruses)
Evaluation of treatment outcomes for patients on first?line regimens in US President's Emergency Plan for AIDS Relief (PEPFAR) clinics in Uganda: predictors of virological and immunological response from RV288 analyses
ConclusionsHigh virological suppression rates are achievable on first?line ART in Uganda. The odds of virological suppression were positively associated with efavirenz use and improvements in CD4 cell percentage and total lymphocyte count and negatively associated with the cost of travel to the clinic. CD4 cell reconstitution was positively associated with CD4 count at study visit, time on ART, satisfaction with care at clinic, haemoglobin concentration and total lymphocyte count and negatively associated with age. (Source: HIV Medicine)
The exon junction complex is required for definition and excision of neighboring introns in Drosophila [Research Papers]
Splicing of pre-mRNAs results in the deposition of the exon junction complex (EJC) upstream of exon&ndash;exon boundaries. The EJC plays crucial post-splicing roles in export, translation, localization, and nonsense-mediated decay of mRNAs. It also aids faithful splicing of pre-mRNAs containing large introns, albeit via an unknown mechanism. Here, we show that the core EJC plus the accessory factors RnpS1 and Acinus aid in definition and efficient splicing of neighboring introns. This requires prior deposition of the EJC in close proximity to either an upstream or downstream splicing event. If present in isolation, EJC-dependent introns are splicing-defective also in wild-type cells. Interestingly, the most affected intron belongs to the piwi locus, which explains the reported transposon d...
AIDSinfo Glossary App Updated for iOS 7
The free AIDSinfo HIV/AIDS Glossary apps for Apple and Android devices provide on-the-go access to definitions for more than 700 HIV/AIDS-related terms in English and Spanish. The apps also include an audio feature so users can hear the correct pronunciation of each term. &nbsp; The Glossary app for iPhone, iPad, and iPod touch is now optimized for iOS7. The updated app features an iOS7-compatible look and feel and a new icon. The upgrade also included minor bug fixes. &nbsp; Whether you are new to the Glossary app or a long-time user, download the latest, iOS7-optimized version of the app for your Apple device today. Feedback on the updated app is welcome. Please e-mail your comments to ContactUs@aidsinfo.nih.gov. &nbsp; (Source: AIDSinfo At-a-Glance: Offering Information on HIV/AIDS Trea...<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
NIH-Led Scientists Boost Potential of Passive Immunization Against HIV
&quot;Scientists are pursuing injections or intravenous infusions of broadly neutralizing HIV antibodies (bNAbs) as a strategy for preventing HIV infection. This technique, called passive immunization, has been shown to protect monkeys from a monkey form of HIV called simian human immunodeficiency virus, or SHIV. To make passive immunization a widely feasible HIV prevention option for people, scientists want to modify bNAbs such that a modest amount of them is needed only once every few months. &quot;To that end, an NIH-led team of scientists has mutated the powerful anti-HIV bNAb called VRC01 so that, once infused into monkeys, it lasts three times longer in blood than unmutated VRC01, collects in rectal mucosal tissue, and persists there more than twice as long as unmutated VRC01. Conce...
Barriers to sight impairment certification in the UK: the example of a population with diabetes in East London
Conclusions: Our data shows that sight certification in patients with diabetes might be underestimated and these patients often have non-diabetes related visual loss. We propose that data on certifiable visual impairment could serve, along with existing certification databases, as a resource for quality of care standards assessment and service provision for patients with diabetes. (Source: BMC Ophthalmology - Latest articles)
Department of AIDS Control to be merged with Health Ministry; decision riles activists
The merger was first proposed in the 12th Five-Year Plan. Planning Commission suggested that the DAC should be integrated with the National Health Mission . (Source: The Economic Times)
Researchers Should Use More Data, Not Just the HIV Sequence Compendium, for Epidemiology and Other HIV Research
AIDS Research and Human Retroviruses , Vol. 0, No. 0. (Source: AIDS Research and Human Retroviruses)
Molecular Epidemiology, Phylogeny, and Phylodynamics of CRF63_02A1, a Recently Originated HIV-1 Circulating Recombinant Form Spreading in Siberia
AIDS Research and Human Retroviruses , Vol. 0, No. 0. (Source: AIDS Research and Human Retroviruses)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Antibodies, together with viral ?inducers,? found to control HIV in mice
A new strategy devised by researchers at Rockefeller University harnesses the power of broadly neutralizing antibodies, along with a combination of compounds that induce viral transcription, in order to attack latent reservoirs of HIV-infected cells in an approach termed 'shock and kill.' More &#187; (Source: The Rockefeller University Newswire)
Health Literacy and Cultural Competency of FDA Consumer Materials
Healthcare decisions made by members of the public and health care practitioners, including when seeking information to guide decisions regarding medical treatments for conditions such as HIV/AIDS and Hepatitis C, are likely to benefit from epidemiologic evidence. However, the level of information available to the public may not match their health literacy and other needs. Health literacy is the ability to obtain/process/understand health information in order to make healthy decisions. In addition health literacy is considered a social determinant of health, with low health literacy associated with medication errors, low rates of treatment compliance, and higher mortality. (Source: Annals of Epidemiology)
One Woman?s Struggle to Find the Right Contraceptive
Because men wield power in decisions around pregnancy, family planning services should include them. Couple-centred family planning services are sorely needed in Africa. Credit: Mercedes Sayagues/IPSBy Miriam GathigahNAIROBI, Aug 14 2014 (IPS) Beatrice Njeri had just come home from her job as a janitor at a primary school in Nairobi. It was August 2009. Arriving home earlier than usual, the married mother of two found her husband waiting for her in their shanty at Kisumu Ndogo, in the sprawling Kibera slums. He had just discovered he was HIV positive. A week later, she too tested positive. Both were 29 years old at the time. ?We were very young and knew very little about HIV,? she says. Having had two daughters, both HIV negative, they desired a son, but decided not to have another bab...
South Africa: TAC Pickets Michael Mapongwana Baby Unit
[GroundUp]"There is no privacy, you are asked in front of everyone what your baby's HIV status is. It is dirty and the staff is very disrespectful in the way they speak to patients. I don't go to that clinic anymore; it's been a year now. Because of their treatment I did something I shouldn't have done, I tested my child for HIV myself, because I too work at a clinic." (Source: AllAfrica News: HIV-Aids and STDs)
Compare mDCs and pDCs between two distinct patients groups in acute HIV-1 infection.
In this study, we enrolled two different groups of subjects with acute HIV-1 infection. One group progressed to CD4 counts below 200 cells/?l within 2 years of HIV-1 infection (CD4 Low Group), while the other group maintained CD4 counts above 500 cells/?l (CD4 High Group). We did not find statistical difference in the pDC number between the two groups during acute HIV-1 infection. However, the mDC number was significantly lower in the CD4 Low Group than in the CD4 High Group. PMID: 25104967 [PubMed] (Source: AIDS Research and Therapy)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
HCV RNA viral load is independent from CD4 cell count and plasma HIV RNA viral load in immunocompetent HIV-HCV co-infected patients: a 3-years follow-up study.
CONCLUSIONS: The HCV RNA load, a known pretreatment predictor of response to antiviral therapy, was independent of the two main parameters of HIV disease, plasma HIV RNA and CD4 cell count, over an observation time of 3 years in patients with recovered or spontaneously maintained immunocompetence. PMID: 25104966 [PubMed] (Source: AIDS Research and Therapy)
Editorial: The Monocyte/Macrophage in the Pathogenesis of AIDS: The Next Frontier for Therapeutic Intervention in the CNS and Beyond: Part II.
We present several additional articles, in Part II of this issue, further emphasizing the importance of host-virus interactions in disease and consideration for avenues of therapy and new investigation. An interesting mechanism of host dysregulation of gene expression is demonstrated here by Duan et al. where HIV-1 Tat protein impairs factalkine gene expression, leading to impaired microglial-neuronal interactions and concomitant activation of inflammation (i.e. the NFkB pathway) [3]. It is interesting to speculate that Tat, through fractalkine dysregulation, may alter the retention and migration properties of peripheral derived macrophages, and thereby contributes to the pathogenesis of HIV in CNS as well as the reservoir of infection. At the same time, down-modulation of the host-factor,...
Rwanda: My Story of Living With HIV for More Than 30 Years
[Key Correspondents]I was born with HIV and more than 30 years later I am still alive! I am sharing my story to comfort people newly infected with HIV as well as long-term survivors. Many people write about HIV but we rarely hear from people living with HIV themselves. (Source: AllAfrica News: HIV-Aids and STDs)
Implementation of a rapid HIV testing programme favourably impacts provider opinions on emergency department HIV testing
Conclusions Overall support for ED HIV testing increased after establishment of a rapid testing programme. (Source: Emergency Medicine Journal)
Hepatitis C virus core protein enhances HIV-1 replication in human macrophages through TLR2, JNK, and MEK1/2-dependent upregulation of TNF-? and IL-6
Increased progression rates to acquired immunodeficiency syndrome (AIDS) and liver disease have been reported in individuals coinfected with human immunodeficiency virus type 1 (HIV-1) and hepatitis C virus (HCV) [1,2]. Strikingly, activation of CD4+ T cells, macrophages, and dendritic cells enhances HIV-1 viral replication [3?6]. In HIV-1-infected individuals, higher viral loads and faster progression to AIDS correlate with systemic markers of immune activation [7]. Furthermore, cells latently infected by HIV-1 serve as long-lasting viral reservoirs and hinder the eradication of HIV-1 from infected patients with antiretroviral treatment. (Source: FEBS Letters)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Relating working memory to compression parameters in clinically-fit hearing aids.
Conclusions: Despite the expectation of greater variability from differences in compression implementation, number of compression channels or attendant signal processing, the relationship between working memory and compression speed showed a similar pattern as results from more controlled, laboratory-based studies. PMID: 25123548 [PubMed - as supplied by publisher] (Source: American Journal of Audiology)
Mozambique: How Country Is Coping With Aids
[IPS]Maputo -Mozambique struggles to contain the HIV epidemic with one in ten among its 24 million people infected. Helping them is not easy when only 60 percent of people have access to health services. (Source: AllAfrica News: HIV-Aids and STDs)
Zambia: Pepfar to Honour Champions Striving to Reach Every Zambian With Quality HIV Services
[Times of Zambia]SINCE the US President's Emergency Plan for AIDS Relief (PEPFAR) started working in Zambia just more than 10 years ago, dramatic progress has occurred in the fight against HIV and AIDS. (Source: AllAfrica News: HIV-Aids and STDs)
Tanzania: HIV Infection Among Drug Users High in Zanzibar
[Daily News]Zanzibar -AT least 67 people among drug users in Zanzibar tested HIV positive last year, an indication that the spread of the deadly virus among the group needed addressing. (Source: AllAfrica News: HIV-Aids and STDs)
Nigeria: Yemi Alade to Fight Cancer, Aids Through Social Media
[Daily Independent]Nigerian artiste, Yemi Alade, says she plans to create an awareness campaign to help women fight cervical cancer, HIV/AIDS and other diseases, which affect women. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Kenya: Too Trusting Population Hampers Aids Prevention
[Capital FM]Nairobi -Don't stare, we're told. Also, "if you come across your relative, don't see them until they see you," Dr Kenneth Ngure tells us. (Source: AllAfrica News: HIV-Aids and STDs)
Which dimensions of disability does the HIV Disability Questionnaire (HDQ) measure? A factor analysis.
Conclusions: The HDQ has six domains: physical symptoms and impairments; cognitive symptoms and impairments; mental and emotional health symptoms and impairments; uncertainty; difficulties with day-to-day activities and challenges to social inclusion. These domains establish the scoring structure for the dimensions of disability measured by the HDQ. Implications for Rehabilitation As individuals live longer and age with HIV, they may be living with the health-related consequences of HIV and concurrent health conditions, a concept that may be termed disability. Measuring disability is important to understand the impact of HIV and its comorbidities. The HIV Disability Questionnaire (HDQ) is a self-administered questionnaire developed to describe the presence, severity and episodic nature of ...
Anthropometry and body composition of vertically HIV-infected children and adolescents under therapy with and without protease inhibitors.
CONCLUSIONS: The findings of the study suggest that children and adolescents under protease inhibitors are at higher risk of growth and development deviations, but not at risk of body fat redistribution. PMID: 25115797 [PubMed - as supplied by publisher] (Source: Public Health Nutrition)
Social Participation of School-aged Children Who Use Communication Aids: The Views of Children and Parents.
This article presents findings from interviews with eight 5- to 14-year-old children who used communication aids and their parents about social participation, communicative interactions, and peer relationships. Video- and audio-recordings were transcribed and analyzed using thematic content analysis, and five themes were identified. Two themes reflect parents' views: Communication partners and strategies and Access to aided communication. Three themes reflect perceptions expressed both by children and parents: Participation in society, Interaction opportunities, and Social relationships. The findings provide insights into both the achievements and the challenges experienced by young people who use aided communication. PMID: 25115791 [PubMed - as supplied by publisher] (Source: Augmenta...
Space Oddity: Use of Sleep Aids in Astronauts Astronomical Space Oddity: Use of Sleep Aids in Astronauts Astronomical
Sleep deficiency is pervasive among astronauts before and during space flight, and the reported incidence sleep-promoting medication use is 20 times greater than the proportion of Americans estimated to use hypnotic drugs at any time in a given year. Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Stigma Is a Side-Effect of HIV-Prevention MedicineStigma Is a Side-Effect of HIV-Prevention Medicine
Truvada is a drug that can help people who are not infected avoid contracting the virus that causes AIDS. But some patients are worried the medical community is not up to speed. Kaiser Health News (Source: Medscape Medical News Headlines)
Breaking Open Public Places: UNFPA Launches Coolibah - 21 July 2014
MELBOURNE, Australia &ndash; At the International AIDS Conference 2014 today, UNFPA, the United Nations Population Fund, launched a youth networking zone called the coolibah, where, throughout the week, it will host a range of activities for and with young people, including a series of luncheons with leaders in the field of HIV and AIDS. (Source: UNFPA News)
UNFPA engages young people in the fight against HIV - 21 July 2014
MELBOURNE, Australia &ndash; Every hour, about 80 young people are newly infected with HIV, according to the recently released Gap Report by UNAIDS. The participation and leadership of young people will therefore be critical in bringing the global HIV epidemic to an end. Today, at the 20th International AIDS Conference, UNFPA launched a youth networking zone called the &lsquo;coolibah&rsquo;, where young people will be able to speak with leaders in the field of HIV and AIDS. (Source: UNFPA News)
Premature baby&#039;s shrill cry may be sign of something deeper
Higher pitch could indicate lower activities in nerve that aids digestion (Source: ScienceNOW)
South Africa: Report - South African National Aids Council Annual Performance Plan 2014-15
[Health-e]The South African National AIDS Council (SANAC) outlines its plan for the next three years in this 8-page performance plan. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Africa: Why Male Circumcision Is a Key Weapon in Tackling Aids
[The Herald]Transformative change is afoot among men and boys throughout Southern and Eastern Africa. Millions have bravely stepped up to protect themselves and their partners from HIV. (Source: AllAfrica News: HIV-Aids and STDs)
Rwanda: Lab Services to Be At Centre of HIV/Aids Fight
[New Times]Milk remains a key source of nutrients to fight stunting among children. Taking milk results into good mental and physical development. As far its composition is concerned, this wonder food is rich in proteins, vitamins A, B, B12, nutrients that contribute to strong and healthy bones. This was said by a health and nutritional specialist by the Global Communities/Usaid Ejo Heza while launching a milk campaign targeting lactating mothers and children in Gisagara District last week. (Source: AllAfrica News: HIV-Aids and STDs)
Rwanda: How Truvada ARVs Breed Reckless Sexual Lifestyle
[New Times]Taking care of an HIV patient can be one of the most challenging tasks but not for Suzan Mukandoli, who did not just sit back to watch her elder brother die in agony. Every morning she would make it a point to dress up his wound on the leg and thereafter administer medication. (Source: AllAfrica News: HIV-Aids and STDs)
Breaking Open Public Places: UNFPA Launches Coolibah - 21 July 2014
MELBOURNE, Australia &ndash; At the International AIDS Conference 2014 today, UNFPA, the United Nations Population Fund, launched a youth networking zone called the coolibah, where, throughout the week, it will host a range of activities for and with young people, including a series of luncheons with leaders in the field of HIV and AIDS. (Source: UNFPA News)
UNFPA engages young people in the fight against HIV - 21 July 2014
MELBOURNE, Australia &ndash; Every hour, about 80 young people are newly infected with HIV, according to the recently released Gap Report by UNAIDS. The participation and leadership of young people will therefore be critical in bringing the global HIV epidemic to an end. Today, at the 20th International AIDS Conference, UNFPA launched a youth networking zone called the &lsquo;coolibah&rsquo;, where young people will be able to speak with leaders in the field of HIV and AIDS. (Source: UNFPA News)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Perception of High School Students on risk for acquiring HIV and utilization of Voluntary Counseling and Testing (VCT) service for HIV in Debre-berhan Town, Ethiopia: a quantitative cross-sectional study
Conclusions: Some students were engaged in risky sexual behavior even though they had heard about HIV/AIDS. The perception of risk for acquisition of HIV infection and utilization of VCT were low. Thus, education on topic of HIV/AIDS through integrating as part of school curriculum and encouraging the existing health institutions to provide youth-friendly sexual counseling services including VCT for HIV are strongly recommended. (Source: BMC Research Notes)
Abacavir/lamivudine plus darunavir/ritonavir in routine clinical practice: a multicentre experience in antiretroviral therapy-naive and -experienced patients
Conclusions In our cohort, abacavir/lamivudine + darunavir/ritonavir was safe, well tolerated and achieved high rates of virological suppression. In a proportion of patients, discontinuation of this effective regimen was possibly due to non-medical reasons. (Source: Journal of Antimicrobial Chemotherapy)
Highlights from this issue
In an era of scarce resources, how can we best target prevention activities and screening? This month, Simms and colleagues address this question in an editorial exploring the potential contribution of geographic information systems (GIS) to sexual health research.1 This is a perennial problem, but new technologies may hold potential for improved targeting of resources without compromising confidentiality. This is definitely worth a read for colleagues working with commissioners to plan their services. The British Association for Sexual Health and HIV (BASHH) has revised its standards for the management of sexually transmitted infections, originally published in collaboration with the Medical Foundation for HIV and Sexual Health in 2010. Lowbury and Ahmed-Jushuf introduce this new edition ...
Standards for the management of sexually transmitted infections--2014
Despite progress in recent years the UK continues to have high rates of sexually transmitted infections (STIs), with some population groups disproportionately at risk of poor sexual health. It is widely accepted that effective commissioning of services and interventions is key to improving health outcomes. To support commissioners and providers in this aim and to help them achieve high quality services for the populations they serve, the British Association for Sexual Health and HIV, and MEDFASH (Medical Foundation for HIV & Sexual Health) have comprehensively revised and updated the Standards for the management of STIs,1 originally published in 2010. There has been a momentous change across the health commissioning landscape in England since the original standards were launched. Local...
HIV and sexually transmitted infection-related risks among female sex workers in Mongolia: second-generation surveillance survey, 2011-2012
Conclusions A syphilis epidemic continues to grow among FSWs in Mongolia. These women are at high risk of HIV transmission if introduced into their sexual networks. With the increase in migration of mining workers in Mongolia, introduction of HIV may be imminent. Efforts to intensify treatment and prevention programmes among FSWs are needed. (Source: Sexually Transmitted Infections)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Strategies for promoting HIV testing uptake: willingness to receive couple-based and collective HIV testing among a cross-sectional online sample of men who have sex with men in China
We examined the potential usefulness of couple-based and collective HIV testing strategies among Chinese MSM. Methods A cross-sectional online survey was conducted among 1113 MSM in 2013. Multivariable logistic regression analyses were conducted to identify factors associated with willingness to receive couple-based and collective testing. Results Acceptability of couple-based testing was very high among participants (86.1%), with a moderate level of interest in collective testing (43.2%). Being &lsquo;out&rsquo; to others about one's sexual identity (adjusted OR (AOR)=1.48, 95% CI 1.01 to 2.17) and having ever had an HIV test (AOR=3.05, 95% CI 2.10 to 4.33) were associated with willingness to receive couple-based testing. Having multiple male anal sex partners in the past 3&nbsp;months ...
Sexual risk typologies and their relationship with early parenthood and STI outcomes among urban African-American emerging adults: a cross-sectional latent profile analysis
Conclusions LCA identified distinct risk clusters that predicted sexual health outcomes and can inform targeted interventions for a minority youth population disproportionately affected by HIV, other STIs, and early parenthood. (Source: Sexually Transmitted Infections)
The effect of mobility on sexual risk behaviour and HIV infection: a cross-sectional study of men who have sex with men in southern India
Conclusions Mobile MSM have a higher likelihood of contracting HIV. Interventions extending the ways to reach out to MSM with greater mobility may augment ongoing efforts to reduce the spread of HIV/AIDS in India. (Source: Sexually Transmitted Infections)
Prevalence, correlates and trends in seroadaptive behaviours among men who have sex with men from serial cross-sectional surveillance in San Francisco, 2004-2011
Conclusions HIV seroadaptive behaviours remain common in San Francisco MSM, have increased in the last decade and are practiced differently by MSM with different sexual health knowledge and outcomes. Public health researchers and officials should continue to document the prevalence, intentionality, efficacy and safety of seroadaptive behaviours among diverse communities of MSM. (Source: Sexually Transmitted Infections)
A stair-climbing test for measuring mechanical efficiency of ambulation in adults with chronic stroke.
Conclusion: With a minimal detectable change of 0.6% (0.053 of average MEnet score of 10.4%), MEnet values from the stair-climbing test seem sufficiently meaningful to estimate ambulatory ability and its changes with interventions or walking aids in adults with hemiparesis. Implications for Rehabilitation Ambulatory ability can be estimated from mechanical efficiency, obtained from a 5-min stair-climbing test utilizing a 4-step stair, to measure external work, and the change in heart rate above rest to estimate the metabolic cost of the task. A change of &gt;?0.6% in mechanical efficiency by this stair-climbing test indicates a significant change in ambulatory ability of persons with hemiparesis. PMID: 25113573 [PubMed - as supplied by publisher] (Source: Disability and Rehabilitatio...<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Discovery of a novel HIV-1 integrase inhibitor from natural compounds through structure based virtual screening and cell imaging
Human immunodeficiency virus (HIV) is the virus that causes the fatal acquired immunodeficiency syndrome (AIDS) [1]. The HIV life cycle is usually divided into six steps: attachment and fusion, reverse transcription, integration of viral DNA into host genome, transcription, assembly and budding [2,3]. Integrase, also called p31, is the enzyme responsible for integration. Integrase is consisted of three domains: N-termianl domain (NTD, residues 1?49), catalytic core domain (CCD, residues 50?212) and C-terminal domain (CTD, residues 213?288) [4]. (Source: FEBS Letters)
Tuberculosis Infection Control: Potential Benefit of a New Rapid Tuberculosis Test in a Human Immunodeficiency Virus/AIDS Reference Hospital
Marcelo Cordeiro-Santos, MD, PhD; Anete Trajman, MD, PhD; Frank Cobelens, MD PhD; Betina Durovni, MD; Maurício Gonçalves, MSc; Samira Bührer-Sékula, PhD; Valeria Saraceni, MD PhD Infection Control and Hospital Epidemiology, Volume 35, Issue 9, Page 1206-1207, September 2014. (Source: Infect Control Hosp Epidemiol Latest Issue)
Generation and Characterization of an HIV-1 Subtype C Transmitted and Early Founder Virus Consensus Sequence
AIDS Research and Human Retroviruses , Vol. 0, No. 0. (Source: AIDS Research and Human Retroviruses)
Melanocyte Biology and Function with Reference to Oral Melanin Hyperpigmentation in HIV-Seropositive Subjects
AIDS Research and Human Retroviruses , Vol. 0, No. 0. (Source: AIDS Research and Human Retroviruses)
Impact of an Adherence Program to Antiretroviral Treatment on Virologic Response in a Cohort of Multitreated and Poorly Adherent HIV-Infected Patients in Spain
AIDS Patient Care and STDs , Vol. 0, No. 0. (Source: AIDS Patient Care and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Marurani Update!
Ten. The number of days we have left to squeeze in community day, the rest of our testings, and as many teachings as possible. The number of days we have left in the village. The number of days we have left in Tanzania. It?s safe to say that this number shocks all of us and it?s hard to believe that of the two months we started with, ten days is all that remains. While we?ve been here, we?ve taught a huge variety of people, at a huge variety of places. We?ve taught at schools, soccer pitches, farms, pubs, churches, mama?s groups, investing groups, and people simply standing by the side of the road. And all the while, even though we came as outsiders, we were welcomed by our home stay families and the entire village as some of their own. All of this has caused the last seven wee...
Seeing Through Virtual Touch for Vision Impaired
Visual impairment comes in many forms, and it's on the rise in America. (Source: Disabled World)
Kenya: Widows in Kenya Tackle HIV in Their Community
[Key Correspondents]When Jacinta Mulatia tested positive for HIV in 2003 it came as a shock to her, she was confused and unsure what to do when faced with extreme stigma in her community. (Source: AllAfrica News: HIV-Aids and STDs)
Africa: South Africa Leads in HIV Prevention Among Gay Groups
[GroundUp]As homophobic discrimination continues to sweep across the African continent, we should be acutely mindful of the diverse ways it harms societies. While we are most aware of the direct effect homophobic physical violence has on sexual minority groups, it is also crucial that we be cognisant of the many insidious ways stigma and discrimination impact not only on sexual minorities but society at large. (Source: AllAfrica News: HIV-Aids and STDs)
Breaking Open Public Places: UNFPA Launches Coolibah - 21 July 2014
MELBOURNE, Australia &ndash; At the International AIDS Conference 2014 today, UNFPA, the United Nations Population Fund, launched a youth networking zone called the coolibah, where, throughout the week, it will host a range of activities for and with young people, including a series of luncheons with leaders in the field of HIV and AIDS. (Source: UNFPA News)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
UNFPA engages young people in the fight against HIV - 21 July 2014
MELBOURNE, Australia &ndash; Every hour, about 80 young people are newly infected with HIV, according to the recently released Gap Report by UNAIDS. The participation and leadership of young people will therefore be critical in bringing the global HIV epidemic to an end. Today, at the 20th International AIDS Conference, UNFPA launched a youth networking zone called the &lsquo;coolibah&rsquo;, where young people will be able to speak with leaders in the field of HIV and AIDS. (Source: UNFPA News)
Africa: Stigma Still a Major Roadblock for Aids Fight in Africa
[IPS]Washington -Though West Africa's massive Ebola outbreak may be dominating the spotlight within the global health community, HIV/AIDS remains an enormous issue for Africa as a whole - a sentiment that Washington officials made clear this week in their discussions of legislative and technological setbacks plaguing progress in fighting the epidemic. (Source: AllAfrica News: Health and Medicine)
Nigeria: Man Stabs Wife to Death, Says 'She Infested Him With HIV'
[Daily Independent]Lagos -Officers of the homicide section of the Criminal Investigations Department, Lagos State Police Command, Yaba, led by Dan Iyama, a Chief Superintendent of Police, (CSP) are trying to unravel the real motive behind the killing of a woman, named Justina James, by a suspect- Katongu Philip, 45. (Source: AllAfrica News: HIV-Aids and STDs)
Adherence Pattern to a Daily Oral Pre-exposure ProphylaxisAdherence Pattern to a Daily Oral Pre-exposure Prophylaxis
What factors are associated with good adherence to daily, oral HIV pre-exposure prophylaxis? JAIDS: Journal of Acquired Immune Deficiency Syndromes (Source: Medscape Today Headlines)
Helping Our Patients Take HIV Pre-Exposure ProphylaxisHelping Our Patients Take HIV Pre-Exposure Prophylaxis
What strategies could promote adherence to HIV pre-exposure prophylaxis? HIV Medicine (Source: Medscape Today Headlines)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Cryptococcal Antigen Positivity Among AIDS PatientsCryptococcal Antigen Positivity Among AIDS Patients
How common is undiagnosed cryptococcal infection in patients with HIV? Morbidity & Mortality Weekly Report (Source: Medscape Today Headlines)
Drug Resistance Among Newly Diagnosed HIV-Infected ChildrenDrug Resistance Among Newly Diagnosed HIV-Infected Children
How should drug resistance in HIV-infected infants and young children be managed? AIDS (Source: Medscape Today Headlines)
Nigeria: HIV/Aids Prevalence Drops in a/Ibom - SACA
[Leadership]The Human Immuno-deficiency Virus and the Acquired Immune Deficiency Syndrome (HIV/AIDS) prevalence rate has dropped in Akwa Ibom State. (Source: AllAfrica News: HIV-Aids and STDs)
Nigeria: Youth Council Organises HIV/Aids Sensitisation Workshop
[Independent]The National Youth Council of Nigeria (NYCN), Cross River chapter, has organised a sensitisation workshop on the Human Immunodeficiency Virus and Acquired Immune Deficiency Syndrome HIV/AIDS as part of activities to mark the 2014 International Youth Week celebration. (Source: AllAfrica News: HIV-Aids and STDs)
Pleuropericardial effusion: a diagnostic conundrum
Pleuropericardial effusion as a presenting feature raises the possibility of infectious, neoplastic and connective tissue disorders.1 However, unusual pathophysiological mechanisms may sometimes pose a diagnostic conundrum in certain clinical contexts. Simultaneous pleuropericardial effusion secondary to obstructive uropathy is such a rare scenario with no report mentioned in the published literature. A 62-year-old man presented with progressive dyspnoea and left flank pain for 1&nbsp;month. A CT scan revealed massive left-sided effusion, mild pericardial effusion (figure 1A,B) and a large staghorn calculi in the left kidney causing grade 4 hydronephrosis (figure 2A,B). Therapeutic thoracentesis revealed a straw-coloured transudative effusion with sugar of 44&nbsp;mg/dL, lactate dehydrogen...<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
How do supply?side factors influence informal payments for healthcare? The case of HIV patients in Cameroon

Comparison of the benefits of cochlear implantation versus contra-lateral routing of signal hearing aids in adult patients with single-sided deafness: study protocol for a prospective within-subject longitudinal trial
DiscussionThis multi-centre trial was designed to provide evidence for the efficacy of cochlear implantationcompared to the contra-lateral routing of signals. A purpose-built sound presentation system andestablished measurement techniques will provide reliable and precise measures of binaural hearing.Trial RegistrationCurrent Controlled Trials ISRCTN33301739 http://www.controlled-trials.com/ISRCTN33301739 (07/JUL/2013) (Source: BMC Ear, Nose and Throat Disorders)
Infection of the optic apparatus and hypothalamus by Mycobacterium haemophilum
We present a case of M haemophilum infection of the optic chiasm, tract, and hypothalamus in a patient with AIDS. (Source: Neurology)
Incidence and risk factors for AIDS-related mortality in HIV patients in China: a cross-sectional study
Conclusions: The effective reduction of AIDS mortality could be improved through timely treatment. (Source: BMC Public Health - Latest articles)
Structural insights for HIV-1 therapeutic strategies targeting Vif.
Authors: Salter JD, Morales GA, Smith HC Abstract HIV-1 viral infectivity factor (Vif) is a viral accessory protein that is required for HIV-1 infection due largely to its role in recruiting antiretroviral factors of the APOBEC3 (apolipoprotein B editing catalytic subunit-like 3) family to an E3 ubiquitin ligase complex for polyubiquitylation and proteasomal degradation. The crystal structure of the (near) full-length Vif protein in complex with Elongin (Elo)B/C, core-binding factor (CBF)? and Cullin (Cul)5 revealed that Vif has a novel structural fold. In our opinion the structural data revealed not only the protein-protein interaction sites that determine Vif stability and interaction with cellular proteins, but also motifs driving Vif homodimerization, which are essential in Vi...<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Breaking Open Public Places: UNFPA Launches Coolibah - 21 July 2014
MELBOURNE, Australia &ndash; At the International AIDS Conference 2014 today, UNFPA, the United Nations Population Fund, launched a youth networking zone called the coolibah, where, throughout the week, it will host a range of activities for and with young people, including a series of luncheons with leaders in the field of HIV and AIDS. (Source: UNFPA News)
UNFPA engages young people in the fight against HIV - 21 July 2014
MELBOURNE, Australia &ndash; Every hour, about 80 young people are newly infected with HIV, according to the recently released Gap Report by UNAIDS. The participation and leadership of young people will therefore be critical in bringing the global HIV epidemic to an end. Today, at the 20th International AIDS Conference, UNFPA launched a youth networking zone called the &lsquo;coolibah&rsquo;, where young people will be able to speak with leaders in the field of HIV and AIDS. (Source: UNFPA News)
Egypt?s Poor Easy Victims of Quack Medicine
Many pharmacies and herbalists in Egypt prescribe their own 'wasfa' (secret drug or herbal elixir). Credit: Cam McGrath/IPSBy Cam McGrathCAIRO, Aug 10 2014 (IPS) Magda Ibrahim first learnt that she had endometrial cancer when she went to a clinic to diagnose recurring bladder pain and an abnormal menstrual discharge. Unable to afford the recommended hospital treatment, the uninsured 53-year-old widow turned to what she hoped would be a quicker and cheaper therapy. A local Muslim sheikh claimed religious incantations, and a suitable donation to his pocket, could cure the cancer. But when her symptoms persisted, Ibrahim consulted a popular herbalist, whose wasfa (secret drug or herbal elixir) was reputed to shrink tumours. ?I felt much better for a few months and thought the tumour was shr...
Breaking Open Public Places: UNFPA Launches Coolibah - 21 July 2014
MELBOURNE, Australia &ndash; At the International AIDS Conference 2014 today, UNFPA, the United Nations Population Fund, launched a youth networking zone called the coolibah, where, throughout the week, it will host a range of activities for and with young people, including a series of luncheons with leaders in the field of HIV and AIDS. (Source: UNFPA News)
UNFPA engages young people in the fight against HIV - 21 July 2014
MELBOURNE, Australia &ndash; Every hour, about 80 young people are newly infected with HIV, according to the recently released Gap Report by UNAIDS. The participation and leadership of young people will therefore be critical in bringing the global HIV epidemic to an end. Today, at the 20th International AIDS Conference, UNFPA launched a youth networking zone called the &lsquo;coolibah&rsquo;, where young people will be able to speak with leaders in the field of HIV and AIDS. (Source: UNFPA News)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Optimal starting point for antiretroviral HIV treatment in a town in Cameroon: a randomised controlled study
Conclusions: In our small sample, relative risk for death did not differ significantly, but deferred treatment seemed to carry no increased survival or other clinical advantage. During the study period, other studies made WHO change its guidelines to conform to our early treatment. The tendency in our study lends support to this policy.Trial registration: ISRCTN22114173 (Source: Epidemiologic Perspectives and Innovations)
Breaking Open Public Places: UNFPA Launches Coolibah - 21 July 2014
MELBOURNE, Australia &ndash; At the International AIDS Conference 2014 today, UNFPA, the United Nations Population Fund, launched a youth networking zone called the coolibah, where, throughout the week, it will host a range of activities for and with young people, including a series of luncheons with leaders in the field of HIV and AIDS. (Source: UNFPA News)
UNFPA engages young people in the fight against HIV - 21 July 2014
MELBOURNE, Australia &ndash; Every hour, about 80 young people are newly infected with HIV, according to the recently released Gap Report by UNAIDS. The participation and leadership of young people will therefore be critical in bringing the global HIV epidemic to an end. Today, at the 20th International AIDS Conference, UNFPA launched a youth networking zone called the &lsquo;coolibah&rsquo;, where young people will be able to speak with leaders in the field of HIV and AIDS. (Source: UNFPA News)
AIDS in Black and White: The Influence of Newspaper Coverage of HIV/AIDS on HIV/AIDS Testing Among African Americans and White Americans, 1993&#8211;2007
(Source: Journal of Health Communication)
A combined chemometric and quantitative NMR analysis of HIV/AIDS serum discloses metabolic alterations associated with disease status
Mol. BioSyst., 2014, Advance ArticleDOI: 10.1039/C4MB00347K, PaperTracy R. McKnight, Hikari A. I. Yoshihara, Lungile J. Sitole, Jeffery N. Martin, Francois Steffens, Debra MeyerCombined chemometric and quantitative analysis of NMR spectra from HIV-infected sera disclosed previously unknown associations between specific metabolites, such as alanine, and disease status.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Mol. BioSyst. latest articles)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Prevalence of dizziness in older people
Conclusion we conclude that dizziness is a very prevalent symptom in the elderly, coexisting with co-morbidities and use of multiple medications. (Source: Revista CEFAC)
Hearing aids dispensed by sus and quality of life
Conclusion 60% of adults and 46% of elderly use hearing aids and present satisfactory quality of life. (Source: Revista CEFAC)
Breaking Open Public Places: UNFPA Launches Coolibah - 21 July 2014
MELBOURNE, Australia &ndash; At the International AIDS Conference 2014 today, UNFPA, the United Nations Population Fund, launched a youth networking zone called the coolibah, where, throughout the week, it will host a range of activities for and with young people, including a series of luncheons with leaders in the field of HIV and AIDS. (Source: UNFPA News)
UNFPA engages young people in the fight against HIV - 21 July 2014
MELBOURNE, Australia &ndash; Every hour, about 80 young people are newly infected with HIV, according to the recently released Gap Report by UNAIDS. The participation and leadership of young people will therefore be critical in bringing the global HIV epidemic to an end. Today, at the 20th International AIDS Conference, UNFPA launched a youth networking zone called the &lsquo;coolibah&rsquo;, where young people will be able to speak with leaders in the field of HIV and AIDS. (Source: UNFPA News)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Stigma Still a Major Roadblock for AIDS Fight in Africa
Rwandan children orphaned by AIDS in Muhanga village. Credit: Aimable Twahirwa/IPSBy Julia HotzWASHINGTON, Aug 9 2014 (IPS) Though West Africa?s massive Ebola outbreak may be dominating the spotlight within the global health community, HIV/AIDS remains an enormous issue for Africa as a whole &#8211; a sentiment that Washington officials made clear this week in their discussions of legislative and technological setbacks plaguing progress in fighting the epidemic. Despite the World Health Organisation?s announcement Friday that Ebola is now an ?international public health emergency,? doctors, academics and policymakers met Thursday at the Washington office of Kaiser Family Foundation (KFF), a health-policy non-profit, to discuss the similarly urgent threat posed by HIV/AIDS, the su...
Table of Contents
(Source: Journal of the Association of Nurses in AIDS Care)
Editorial Board
(Source: Journal of the Association of Nurses in AIDS Care)
Cover 1
(Source: Journal of the Association of Nurses in AIDS Care)
Position Statement: Advanced Practice Registered Nurses Full Practice Authority
It is the position of the Association of Nurses in AIDS Care that: (Source: Journal of the Association of Nurses in AIDS Care)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Retention in Care: Lessons Relearned
When we try to pick out anything by itself we find that it is bound fast, by a thousand invisible cords that cannot be broken, to everything in the universe.John Muir (1838-1914; Fox, 1981, p. 291). (Source: Journal of the Association of Nurses in AIDS Care)
Masthead
(Source: Journal of the Association of Nurses in AIDS Care)
Board of Directors
(Source: Journal of the Association of Nurses in AIDS Care)
Neurodevelopmental outcomes in HIV-exposed-uninfected children versus those not exposed to HIV
(Source: AIDS Care)
Orphan/vulnerable child caregiving moderates the association between women's autonomy and their BMI in three African countries
(Source: AIDS Care)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Site migration in seeking care services from multiple providers is associated with worse clinical outcomes among HIV-infected individuals in Washington, DC
(Source: AIDS Care)
Treatment retention and care transitions during and after the scale-up of HIV care and treatment in Northern Tanzania
(Source: AIDS Care)
Prevalence and correlates of willingness to participate in a rectal microbicide trial among men who have sex with men in Bangkok
(Source: AIDS Care)
Mental health of patients with human immunodeficiency virus in Japan: a comparative analysis of employed and unemployed patients
(Source: AIDS Care)
High prevalence of suicide risk in people living with HIV: who is at higher risk?
(Source: AIDS Care)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Contagiousness under antiretroviral therapy and stigmatization toward people with HIV
(Source: AIDS Care)
Associations between physical activity and sedentary time on components of metabolic syndrome among adults with HIV
(Source: AIDS Care)
Poor retention in care one-year after viral suppression: a significant predictor of viral rebound
(Source: AIDS Care)
Simple, illustrated medicines information improves ARV knowledge and patient self-efficacy in limited literacy South African HIV patients
(Source: AIDS Care)
HIV-related behavioral risk factors among older female sex workers in Guangxi, China
(Source: AIDS Care)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Evidence of increased STI/HIV-related risk behavior among male perpetrators of intimate partner violence in Guatemala: results from a national survey
(Source: AIDS Care)
Gender differences in HIV disclosure, stigma, and perceptions of health
(Source: AIDS Care)
Psychosocial burdens negatively impact HIV antiretroviral adherence in gay, bisexual, and other men who have sex with men aged 50 and older
(Source: AIDS Care)
Survey of HIV care providers on management of HIV serodiscordant couples &#8211; assessment of attitudes, knowledge, and practices
(Source: AIDS Care)
Factors associated with inconsistent condom use in adolescents with negative or unknown HIV status in Northwest Cameroon
(Source: AIDS Care)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Treatment as prevention: are Argentinean HIV care providers willing to adopt earlier antiretroviral therapy?
(Source: AIDS Care)
Theoretical model of critical issues in informed consent in HIV vaccine trials
(Source: AIDS Care)
Editorial: The Monocyte/Macrophage in the Pathogenesis of AIDS: The Next Frontier for Therapeutic Intervention in the CNS and Beyond: Part I.
Authors: Rappaport J Abstract Monocytes, macrophages, and microglia, play multiple roles in the pathogenesis of HIV infection. In addition to providing a tissue reservoir of infection, HIV infected and non-infected macrophages enter and accumulate in the Central Nervous System, where virus infection spreads to resident glial cells including astrocytes and microglia. This process contributes to the secretion of toxic molecules and inflammatory cytokines, which contribute to neuronal damage and promote a spectrum of HIVassociated neurological disorders ranging from HIV dementia to asymptomatic neurocognitive impairment. There appears to be an alteration in the dynamics of monocyte/macrophage subsets as a result of HIV infection, with resulting alterations in immune polarization statu...
Switching Antiretrovirals May Not Enhance HIV TreatmentSwitching Antiretrovirals May Not Enhance HIV Treatment
Changing treatment when the viral load is suppressed can increase the risk for subsequent virologic failure, new research shows. Medscape Medical News (Source: Medscape Hiv-Aids Headlines)
Tanzania: Women Lobby Male Partners to Be Circumcised
[AlertNet]Dar es Salaam -Efrazia Ngwabi has been trying to encourage her husband to get circumcised but her efforts have been hampered by his belief that the practice is against tribal tradition. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Viral Reservoir Seen 'Strikingly' Soon After HIV InfectionViral Reservoir Seen 'Strikingly' Soon After HIV Infection
A reservoir of HIV is established much sooner after infection than was previously thought; measuring that reservoir is the next big challenge. Medscape Medical News (Source: Medscape Today Headlines)
Namibia: MOHSS Awards Multi-Million Tenders
[New Era]Windhoek -HIV-positive patients will soon start taking fixed-dose combination anti-retroviral (ARV) medication, which involves one tablet instead of three to five pills a day, reducing the risk of patients defaulting on their treatment. (Source: AllAfrica News: HIV-Aids and STDs)
Namibia: HIV, Aids Awareness Exhibit Due
[New Era]Windhoek -The Legal Assistance Centre (LAC) will be hosting an exhibition titled Break the Silence an exhibition of international artworks, raising awareness on HIV and AIDS with the collection facilitated by the organization Artists for Human Rights (AFHR). (Source: AllAfrica News: HIV-Aids and STDs)
Africa: U.S., London Foundation Boost Help for African Children With HIV
[State Department]Washington -The U.S. President's Emergency Plan for AIDS Relief (PEPFAR), in partnership with the Children's Investment Fund Foundation (CIFF), launched Accelerating Children's HIV/AIDS Treatment (ACT) on August 6 during the U.S.-Africa Leaders Summit. (Source: AllAfrica News: HIV-Aids and STDs)
Africa: Investments Announced At Symposium for African Spouses
[White House]Washington, DC -INVESTMENTS ANNOUNCED AT SYMPOSIUM FOR AFRICAN SPOUSES (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
South Africa: Searching for Acceptance
[Health-e]Telling your family you are gay is hard. It may be harder in rural small-town South Africa. (Source: AllAfrica News: HIV-Aids and STDs)
Uganda: Kenya Overtaking Uganda in HIV/Aids Management
[Observer]Once touted as the success story of not just the continent, but the world, Uganda seems to be slipping further off that decorated wagon and paving way for new golden girls such as Kenya. (Source: AllAfrica News: HIV-Aids and STDs)
Malawi: Key Stakeholders Should Be Involved in Srh to Reduce HIV/Aids Transmission - VSO
[Malawi News Agency]Nsanje -NGO Voluntary Service Overseas (VSO) has made a bold proclamation that the country cannot make progress in reducing HIV/AIDS transmission among women and adolescent girls unless all key players are fully involved in providing Sexual and Reproductive Health Rights (SRH) services to them. (Source: AllAfrica News: HIV-Aids and STDs)
Proximal Renal Tubular Dysfunction Related to Antiretroviral Therapy Among HIV-Infected Patients in an HIV Clinic in Mexico
AIDS Patient Care and STDs , Vol. 0, No. 0. (Source: AIDS Patient Care and STDs)
Response of discharge, TSS, and E. coli to rainfall events in urban, suburban, and rural watersheds
Environ. Sci.: Processes Impacts, 2014, Advance ArticleDOI: 10.1039/C4EM00327F, PaperH. J. Chen, H. ChangUnderstanding dominant processes influencing microorganism responses to storm events aids in the development of effective management controls on pathogen contamination in surface water so that they are suitable for water supply, recreation, and aquatic habitat.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - J. Environ. Monit. latest articles)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Breaking Open Public Places: UNFPA Launches Coolibah - 21 July 2014
MELBOURNE, Australia &ndash; At the International AIDS Conference 2014 today, UNFPA, the United Nations Population Fund, launched a youth networking zone called the coolibah, where, throughout the week, it will host a range of activities for and with young people, including a series of luncheons with leaders in the field of HIV and AIDS. (Source: UNFPA News)
UNFPA engages young people in the fight against HIV - 21 July 2014
MELBOURNE, Australia &ndash; Every hour, about 80 young people are newly infected with HIV, according to the recently released Gap Report by UNAIDS. The participation and leadership of young people will therefore be critical in bringing the global HIV epidemic to an end. Today, at the 20th International AIDS Conference, UNFPA launched a youth networking zone called the &lsquo;coolibah&rsquo;, where young people will be able to speak with leaders in the field of HIV and AIDS. (Source: UNFPA News)
College students' search for sexual health information from their best friends: An application of the theory of motivated information management
Guided by the theory of motivated information management, this study investigated the extent to which Singaporean college students' sexual health information?seeking behaviour could be accounted for by their anxiety of uncertainty discrepancy, their perceived outcomes of information seeking and their perceived confidence in seeking and coping with sexual health information acquired from their best friends. Taking into account that issue relevance may play a role in individuals' health decision?making, this study also examined the effect of perceived vulnerability on respondents' sexual health information?seeking behaviour. An online survey was conducted with 202 undergraduate students at a university in Singapore. Respondents were asked to report the frequency with which they sought ...
Corrigendum
(Source: AIDS Care)
Stage-Stratified Approach to AIDS-Related Kaposi's Sarcoma: Implications for Resource-Limited Environments [CORRESPONDENCE]
(Source: Journal of Clinical Oncology)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Risk of Cataract among Subjects with Acquired Immune Deficiency Syndrome Free of Ocular Opportunistic Infections
To evaluate the risk of cataract in the setting of AIDS. (Source: Ophthalmology)
The Moderating Role of Sexual Identity in Group Teletherapy for Adults Aging with HIV.
This study examined whether therapy attendance rates and the efficacies of two group-format teletherapies for the treatment of depression (coping effectiveness group training and supportive-expressive group therapy) were comparable for older MSM and older heterosexuals living with HIV. Intervention-outcome analyses found that older MSM and older heterosexuals living with HIV attended comparable numbers of teletherapy sessions. Older heterosexuals living with HIV who received telephone-administered supportive-expressive group therapy reported significantly greater reductions in depressive symptoms than SOC controls. A similar pattern was not found in older MSM. More research is needed to personalize and tailor group teletherapies for older MSM living with HIV. PMID: 25090366 [PubMed - ...
Aging and HIV/AIDS: Neurocognitive Implications for Older HIV-Positive Latina/o Adults.
This study examined the effects of age and ethnicity on NC function in HIV-positive adults. The sample (N = 126; 84 Latina/o and 42 Non-Hispanic White) completed a comprehensive NC battery. Global NC and domain average demographically-corrected t-scores were generated. There were no significant differences between Younger (&lt;50 years) Latina/os and non-Hispanic Whites on Global NC function or NC domains (all p's &gt;.10), with generally small effect sizes. Older Latina/os (?50 years) were significantly more impaired than Older Non-Hispanic Whites on processing speed and learning, with trends in Global NC function and memory. Further, effect sizes fell within the medium to large range (Cohen's d's = .49-1.15). This study suggests that older Latina/os are at potentially greater risk fo...
Substance Use and Sexual Risk Differences among Older Bisexual and Gay Men with HIV.
Authors: Brennan-Ing M, Porter KE, Seidel L, Karpiak SE Abstract Bisexual and gay men are disproportionately affected by HIV/AIDS. Research typically combines these groups into the category of men who have sex with men, and little is known about between-group differences. HIV-positive populations are aging and have high rates of substance use compared to non-infected peers, while substance use among older adults has increased and is associated with unprotected intercourse. Among a sample of 239 HIV-positive bisexual and gay men aged 50 and older, bisexual men were more likely to report cigarette, cocaine, crack, and heroin use compared with gay men. However, bisexual men were less likely to use crystal meth, club drugs, poppers (nitrate inhalers), and erectile dysfunction (ED) medi...
HIV/AIDS in Older Women: Unique Challenges, Unmet Needs.
Authors: Durvasula R Abstract As persons living with HIV/AIDS live longer, both the prevalence and incidence of HIV infection in older women is expected to increase, and this review presents a model and review of the extant literature on older women with HIV/AIDS in the United States. Older women are rarely addressed in the discourse about HIV risk and prevention, and their concerns are often missed by risk-reduction programs that typically target men and younger adults. Societal biases around aging can compound factors such as stigma and disclosure for older women. Primary care providers are often not recommending routine HIV testing to older women, or addressing the impact of age-related physiological changes on risk and sexual health. Many older women may be starting new relatio...<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Africa: Martin O'malley Announces Intention to Resign As Global Fund's Inspector General
[GFO]His departure in early 2015 should give the Board enough time to recruit a replacement (Source: AllAfrica News: HIV-Aids and STDs)
Watch a Science Cop Take on Donald Trump
The Ebola outbreak that is causing such fear and suffering in Africa is a very real and very deadly thing. But the fact is that the nature of the Ebola virus is such that it stands a very low chance of ever causing a pandemic like AIDS or H1N1. That hasn?t stopped America?s great foghorn?Donald Trump?and others like him from spreading all kinds of misinformation about the disease, warning people that patients should not be brought to the U.S. and that flights from West Africa should be stopped, otherwise we face an American epidemic. But Trump and his ilk are committing a science crime?the crime of misinformation. Here?s the truth, from TIME&#8217;s Jeffrey Kluger. &nbsp; &nbsp; (Source: TIME.com: Top Science and Health Stories)
Artist Elana Lamger was inspired by her grandmother to redefine and style disability accessories
The project is the work of artist Elana Langer and photographer Hanna Agar, both from New York, and aims to challenge the stigma around hearing aids and walkers. (Source: the Mail online | Health)
An Epidemic: Top 10 Outbreaks In U.S. History
Throughout the years, epidemics and plagues have shaken up societies and cultures around the world. The latest outbreak that Americans seem to be concerned about is the Ebola epidemic occurring in the African countries of Guinea, Liberia, Sierra Leone and Nigeria.  With experts and doctors saying that the outbreak has the potential to become a full-blown pandemic that will become increasingly more difficult to control, the general public is scared. While the Centers for Disease Control and Prevention continuously keep an eye on public health and any immediate health dangers, the American public still worries about how much control we really have over such outbreaks. Recently, two Americans were brought back to the U.S. to be treated at Emory Hospital in Atlanta after contracting the Ebola...
Antiretrovirals Before Pregnancy Appear to Be SafeAntiretrovirals Before Pregnancy Appear to Be Safe
Pre-exposure prophylaxis is safe during the periconceptual period for women who become pregnant, new research from the Partners PrEP Study shows. Medscape Medical News (Source: Medscape Today Headlines)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Africa: Communiqué De Presse
[UNAIDS]Melbourne -Dix organisations ont reçu le Prix Ruban Rouge pour leur leadership exceptionnel en matière de sida (Source: AllAfrica News: HIV-Aids and STDs)
Africa: UNAIDS and Partners Launch Initiative to Improve HIV Diagnostics
[UNAIDS]Melbourne/Geneva -Partners will advocate for increased funding and price reductions, strengthen efforts to ensure highest quality diagnostic services and forge partnerships to close diagnostic access gaps. (Source: AllAfrica News: HIV-Aids and STDs)
Africa: UNAIDS Report Shows That 19 Million of the 35 Million People Living With HIV Today Do Not Know That They Have the Virus
[UNAIDS]Geneva -In sub-Saharan Africa, nearly 90% of people who know their HIV-positive status are on treatment-ending the AIDS epidemic by 2030 will require smart scale-up to close the gap (Source: AllAfrica News: Health and Medicine)
Africa: Declining Investment Could Slow Research and Rollout of New HIV Prevention Options
[UNAIDS]Melbourne, Australia -Report shows prevention R&D funding falls 4% due to public sector research budget reductions in US, Europe (Source: AllAfrica News: HIV-Aids and STDs)
Africa: Ten Organizations Receive Red Ribbon Award for Outstanding Community Leadership On Aids
[UNAIDS]Ten exceptional community-based organizations have won the 2014 Red Ribbon Award for their inspiring work in reducing the impact of the AIDS epidemic. They were presented with the prestigious prize in a special session at the 20th International AIDS Conference (AIDS 2014) in Melbourne, Australia. The Red Ribbon Award is the world's leading award for innovative and outstanding community work in the response to the AIDS epidemic. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Africa: Global Leaders Commit to Ending the Aids Epidemic in Cities By 2030
[UNAIDS]Melbourne -In a meeting initiated by UNAIDS and hosted by the city of Melbourne, Australia, global leaders agreed that cities and local leadership are the key to ending the AIDS epidemic by 2030. The inaugural Cities for Social Transformation meeting took place on the sidelines of the 20th International AIDS Conference. Mayors and representatives of 18 cities, governors, senior members of parliament, health ministers, a Head of State and senior health professionals attended the event. (Source: AllAfrica News: HIV-Aids and STDs)
Africa: Kaiser/UNAIDS Study Finds Dip in Donor Government Commitments for Aids in 2013
[UNAIDS]Melbourne, Australia -Actual disbursements in 2013 increased 8% as some funds from earlier years were spent (Source: AllAfrica News: HIV-Aids and STDs)
Nigeria: HIV/Aids Kills More Than Ebola, Says NACA DG
[This Day]Notwithstanding the global threat posed by the infectious Ebola Virus Disease (EVD), the Director General of the National Agency for the Control of (AIDS) (NACA), Prof. John Idoko, has said that the virus does not kill as much as HIV/AIDS. (Source: AllAfrica News: HIV-Aids and STDs)
Zimbabwe: Kicking HIV Out of Hibernation
[The Herald]A follower of one of the many Pentecostal churches in Zimbabwe hops and runs as he makes his way to the podium. It is a cool Sunday afternoon in March 2014 and he stands in front of over 30 000 other followers to announce that he has been cured of HIV and has his latest results to prove it. (Source: AllAfrica News: HIV-Aids and STDs)
Nigeria: Stakeholders Worry Over Sustainability of HIV/Aids Post 2015
[Daily Trust]As the deadline for the achievement of the MDGs goal draws closer, stakeholders in the HIV/AIDS sector are concerned over the sustainability of the project so as not relegate on the successes gained in eliminating the virus by 2030. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Rwanda: Scientists to Put Lab Services At Centre of HIV/Aids Fight
[New Times]As the world comes together to try and tackle HIV/Aids, an initiative by the African Society for Laboratory Medicine (ASLM) and UNAIDS is rooting for laboratory services to be placed at the forefront of the fight. (Source: AllAfrica News: HIV-Aids and STDs)
Nigeria: 'We Need Commitment to Eliminate HIV/Aids By 2030'
[Leadership]Abuja -The director general, National Agency for the Control of AIDS (NACA), Prof John Idoko and stakeholders in the sector have solicited for support and commitment from relevant bodies to sustain the country's set goal of eliminating the HIV/AIDS virus by 2030. (Source: AllAfrica News: HIV-Aids and STDs)
Angola: Inls Reiterates Importance of Breastfeeding
[ANGOP]Luanda -The National Institute for Combat AIDS (INLS) has reiterated the importance of breastfeeding in the first six months of the child's life, due to its many essential nutrients for the health of minors. (Source: AllAfrica News: HIV-Aids and STDs)
Antiretroviral treatment adherence as a mediating factor between psychosocial variables and HIV viral load
Psychosocial factors may directly impact HIV health measures such as viral load (VL), whether or not patients are taking antiretroviral treatment (ART) consistently. Structural equation modeling plus Baron and Kenny's (1986) four-step approach were used to test a mediated model predicting VL among 246 HIV-infected adults who were on ART. Exogenous variables were social support, barriers to adherence, and stress. Moderators were alcohol use, marijuana use, and neurocognitive impairment. A small positive association between marijuana use and ART adherence approached significance. (Source: Journal of the Association of Nurses in AIDS Care)
Novel Antiretroviral Drugs and Renal Function Monitoring of HIV Patients.
Authors: Maggi P, Montinaro V, Mussini C, Di Biagio A, Bellagamba R, Bonfanti P, Calza L, Cherubini C, Corsi P, Gargiulo M, Montella F, Rusconi S Abstract Chronic kidney disease is a major comorbidity in patients affected by HIV infection. In addition, the introduction of new antiretroviral agents that interact with creatinine transporters is raising some concerns. In this review we analyze the currently available data about three new antiretroviral drugs and one new pharmacokinetic enhancer. Three of them (rilpivirine, cobicistat, dolutegravir) have shown some interactions with renal function, while tenofovir alafenamide fumarate reduces the plasmatic concentration of the parent drug. The future use of tenofovir alafenamide seems to be encouraging in order to reduce the renal inte...<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Pre-Exposure Prophylaxis for the Primary Prevention of HIV in At-Risk Women: Empowerment and Equity Revisited.
Authors: Kofman A, Adashi EY Abstract Women continue to bear a disproportionate burden of the HIV epidemic's impact. The last three years have witnessed the explosive emergence of pre-exposure prophylaxis as a viable, woman-initiated, and woman-controlled candidate for the primary prevention of HIV in women. These developments have proven particularly significant for at-risk women in environments where negotiation of safe sex is difficult. In this review, we trace the recent evolution of the pre-exposure prophylaxis vision for women, delineate the clinical trials that made it all possible, and discuss ongoing efforts required for its full actualization. PMID: 25102335 [PubMed - as supplied by publisher] (Source: AIDS Reviews)
Role of RANKL-RANK/Osteoprotegerin Pathway in Cardiovascular and Bone Disease Associated with HIV Infection.
Authors: Kelesidis T, Currier JS, Yang OO, Brown TT Abstract Patients with HIV?1 infection often develop multiple complications and comorbidities, including osteoporosis and atherosclerosis. The receptor activator of nuclear factor kappa-B/receptor activator of nuclear factor kappa-B ligand/osteoprotegerin axis has been identified as a possible common link between osteoporosis and vascular diseases. Since the discovery of this axis, much has been learned about its role in controlling skeletal biology and less about its role in the context of vascular biology. However, the exact role of the receptor activator of nuclear factor kappa-B ligand/osteoprotegerin axis in HIV infection is not completely understood. In this review we examine the mechanisms by which inflammation and immune...
Monkey-adapted HIV-1 highlights in vivo significance of restriction factors.
Authors: Kirmaier A, Johnson WE Abstract HIV-1 was isolated 31 years ago, yet models for studying HIV-1 pathogenesis in vivo are still lacking. Recent experiments using an HIV-1 strain engineered to replicate in macaques recapitulate several important features of human AIDS, and provide insight into the genetics of cross-species transmission and emergence of pathogenic retroviruses. PMID: 25127418 [PubMed - as supplied by publisher] (Source: Trends in Microbiology)
2 First Ladies Share Tales of Budding Partnership and Life in the Spotlight
Michelle Obama and Laura Bush sponsored a forum for the spouses of visiting African leaders and shared the stage with a rapport born of the shared opportunities and burdens of their role. (Source: NYT)
HIV Rates Lower in Women With Circumcised PartnersHIV Rates Lower in Women With Circumcised Partners
The first real-world evidence supports the benefit of male circumcision. Medscape Medical News (Source: Medscape Medical News Headlines)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Bush Urges Renewed Fight Against Deadly Diseases in Africa
Former President George W. Bush, speaking at a health forum in Washington, spoke of ?the beginning of the end of AIDS.? (Source: NYT)
Ghana: Peer Educators Train On HIV/Aids
[Ghana Govt.]A forty (40) peer educators have undergone a 3-day training programme to provide Community Based Comprehensive Sexual Education, (CBCSE) on HIV/AIDS prevention and management to adolescents and young people in the Bawku municipality. (Source: AllAfrica News: HIV-Aids and STDs)
Eating any fish once a week aids future brain health regardless of omega-3 content
Fish eaters had more grey matter in areas responsible for memory, say Pittsburgh researchers. But the fish must be grilled or baked - and not fried. (Source: the Mail online | Health)
South Africa: Children Blame Defaulting for Mother's Death
[Health-e]Thabang Malekutu, 18, is raising three younger siblings following his mother's recent death due to AIDS-related illnesses after she defaulted on treatment. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
?I Pray That They Accept Me Without Scolding:? Experiences with Disengagement and Re-Engagement in HIV Care and Treatment Services in Tanzania
AIDS Patient Care and STDs , Vol. 0, No. 0. (Source: AIDS Patient Care and STDs)
Age at Antiretroviral Therapy Initiation Predicts Immune Recovery, Death, and Loss to Follow-Up Among HIV-Infected Adults in Urban Zambia
AIDS Research and Human Retroviruses , Vol. 0, No. 0. (Source: AIDS Research and Human Retroviruses)
Regular Book review: Children Caring for Parents with HIV and AIDS: Global Issues and Policy Responses
(Source: Childhood)
Inpatient pharmacological sleep aid utilization is common at a tertiary medical center
CONCLUSIONSDespite increasing evidence of risks such as delirium or falls, pharmacological sleep aid use in general wards remains common, even in elderly patients. Medication administration time is frequently suboptimal. Many previously sleep medication?naïve patients leave the hospital with a sleep aid prescription. Further research is needed to understand the factors that contribute to the high rate of sleep medication use in hospitalized patients. Journal of Hospital Medicine 2014. © 2014 Society of Hospital Medicine (Source: Journal of Hospital Medicine)
Mortality trends show more people with HIV dying from non AIDS cancers.
Authors: Abstract An investigation into mortality trends in people with HIV has found a fall in the percentage of deaths attributable to AIDS related causes but an increase in deaths from non AIDS cancers. PMID: 25095930 [PubMed - in process] (Source: Nursing Standard)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Knee posture during gait and global functioning post-stroke: a theoretical ICF framework using current measures in stroke rehabilitation.
Conclusions: AKP restricts functioning and participation. Implications for Rehabilitation Identification of abnormal knee posture in gait can indicate potential assessment and treatment priorities, e.g. knee flexor strength is a major determinant of functioning in patients with abnormal knee posture and should be assessed. The identification of an abnormal knee posture post-stroke seems relevant for planning patient's long-term needs (e.g. amount of caregiver support). The interpretation of functional measures based on the ICF framework can enhance clinical-reasoning in rehabilitation post-stroke. PMID: 25095902 [PubMed - as supplied by publisher] (Source: Disability and Rehabilitation)
Breaking Open Public Places: UNFPA Launches Coolibah - 21 July 2014
MELBOURNE, Australia &ndash; At the International AIDS Conference 2014 today, UNFPA, the United Nations Population Fund, launched a youth networking zone called the coolibah, where, throughout the week, it will host a range of activities for and with young people, including a series of luncheons with leaders in the field of HIV and AIDS. (Source: UNFPA News)
UNFPA engages young people in the fight against HIV - 21 July 2014
MELBOURNE, Australia &ndash; Every hour, about 80 young people are newly infected with HIV, according to the recently released Gap Report by UNAIDS. The participation and leadership of young people will therefore be critical in bringing the global HIV epidemic to an end. Today, at the 20th International AIDS Conference, UNFPA launched a youth networking zone called the &lsquo;coolibah&rsquo;, where young people will be able to speak with leaders in the field of HIV and AIDS. (Source: UNFPA News)
Africa: USAID Official's 5 Take-Aways From Aids 2014
[State Department]This blog post by David Stanton was first posted on the U.S. Agency for International Development's Impact blog. Stanton is the director of USAID's Office of HIV/AIDS. (Source: AllAfrica News: HIV-Aids and STDs)
Predicting the Probability of Experiencing Clinically Significant Drug?Drug Interactions Involving Boceprevir-Containing Hepatitis C Therapy Among Patients Coinfected with Hepatitis C and HIV
AIDS Patient Care and STDs , Vol. 0, No. 0. (Source: AIDS Patient Care and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
South Africa: Treatment Action Campaign in a Tavern
[GroundUp]People should view taverns as part of the community, where young people can meet to enjoy themselves, and not as enemies, community activists told a meeting at the weekend of the Kuyasa branch of the Treatment Action Campaign. (Source: AllAfrica News: HIV-Aids and STDs)
People with HIV May Be at Lower Risk for Multiple Sclerosis
Constant immune system suppression may be the reason why, researchers say Source: HealthDay Related MedlinePlus Pages: HIV/AIDS, Multiple Sclerosis (Source: MedlinePlus Health News)
A Qualitative Study of Underutilization of the AIDS Drug Assistance Program
In our previous work, we demonstrated underutilization of the AIDS Drug Assistance Program (ADAP) at an HIV clinic in Alabama. In order to understand barriers and facilitators to utilization of ADAP, we conducted focus groups of ADAP enrollees. Focus groups were stratified by sex, race, and historical medication possession ratio as a measure of program utilization. We grouped factors according to the social-ecological model. We found that multiple levels of influence, including patient and clinic-related factors, influenced utilization of antiretroviral medications. (Source: Journal of the Association of Nurses in AIDS Care)
Violence Experiences Among HIV-Infected Women and Perceptions of Male Perpetrators' Roles: A Concurrent Mixed Method Study
This study was designed to (a) explore the personal, cognitive, and psychosocial factors of intimate partner violence among women with HIV; (b) explore the perceptions of male perpetrators' roles in contributing to violence; and (c) determine the implications for methodological and data source triangulation. A concurrent Mixed Method study design was used, including 30 African American male and female participants. Quantitative data were analyzed using descriptive statistics. (Source: Journal of the Association of Nurses in AIDS Care)
Nigeria: Nigeria Wakes Up to Its Aids Threat
[IPS]Tope Tayo's marriage broke up 11 years ago after she tested positive for HIV. Her angry and embarrassed husband took away their only child. Three months later, when the one year old boy tested positive, the husband dumped him with Tayo and absconded. (Source: AllAfrica News: Health and Medicine)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Simplification to rilpivirine/emtricitabine/tenofovir disoproxil fumarate from ritonavir-boosted protease inhibitor antiretroviral therapy in a randomized trial of HIV-1 RNA-suppressed participants: Erratum
No abstract available (Source: AIDS)
Tanzania: HIV/Aids Fund to Start Next Year
[Daily News]TANZANIA Commission for AIDS (TACAIDS) Executive Chairperson, Dr Fatma Mrisho, said the much awaited Tanzania HIV/AIDS Fund will be operational by the next financial year. (Source: AllAfrica News: HIV-Aids and STDs)
Eritrea: Southern Region - Endeavors Being Made As Regards Control of HIV/Aids and TB Witness More Impact
[Shabait]Mendefera -The Health Ministry's branch in the Southern region has indicated that the endeavors being made as regards control of HIV/AIDS and TB have witnessed more impact equitably. (Source: AllAfrica News: HIV-Aids and STDs)
Genome editing eradicates HIV-1 [Medical Sciences]
AIDS remains incurable due to the permanent integration of HIV-1 into the host genome, imparting risk of viral reactivation even after antiretroviral therapy. New strategies are needed to ablate the viral genome from latently infected cells, because current methods are too inefficient and prone to adverse off-target effects. To eliminate... (Source: Proceedings of the National Academy of Sciences)
Power analysis and sample size estimation for sequence-based association studies
Motivation: Statistical methods have been developed to test for complex trait rare variant (RV) associations, in which variants are aggregated across a region, which is typically a gene. Power analysis and sample size estimation for sequence-based RV association studies are challenging because of the necessity to realistically model the underlying allelic architecture of complex diseases within a suitable analytical framework to assess the performance of a variety of RV association methods in an unbiased manner. Summary: We developed SEQPower, a software package to perform statistical power analysis for sequence-based association data under a variety of genetic variant and disease phenotype models. It aids epidemiologists in determining the best study design, sample size and statistical te...<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Levels of circulating myeloid subpopulations and of heme oxygenase-1 do not predict CD4+ T cell recovery after the initiation of antiretroviral therapy for HIV disease
The level (or frequency) of circulating monocyte subpopulations such as classical (CD14hiCD16-) and non-classical (CD14dimCD16+) monocytes varies during the course of HIV disease progression and antiretroviral therapy (ART). We hypothesized that such variation and/or differences in the degree to which these cells expressed the immunoregulatory enzyme, heme oxygenase-1 (HO-1), would be associated with CD4+ T cell recovery after the initiation of ART. This hypothesis was tested in a cross-sectional study of four groups of HIV-infected subjects, including those who were seronegative, untreated virologic controllers [detectable viral load (VL) of 10,000 copies/mL], and ART-mediated virologic controllers [VL < 75 copies/mL]. A longitudinal analysis of ART-treated subjects was also performed alo...
The Association Between Depressive Symptoms, Anger, and Perceived Support Resources Among Underserved Older HIV Positive Black/African American Adults
AIDS Patient Care and STDs , Vol. 0, No. 0. (Source: AIDS Patient Care and STDs)
Breaking Open Public Places: UNFPA Launches Coolibah - 21 July 2014
MELBOURNE, Australia &ndash; At the International AIDS Conference 2014 today, UNFPA, the United Nations Population Fund, launched a youth networking zone called the coolibah, where, throughout the week, it will host a range of activities for and with young people, including a series of luncheons with leaders in the field of HIV and AIDS. (Source: UNFPA News)
UNFPA engages young people in the fight against HIV - 21 July 2014
MELBOURNE, Australia &ndash; Every hour, about 80 young people are newly infected with HIV, according to the recently released Gap Report by UNAIDS. The participation and leadership of young people will therefore be critical in bringing the global HIV epidemic to an end. Today, at the 20th International AIDS Conference, UNFPA launched a youth networking zone called the &lsquo;coolibah&rsquo;, where young people will be able to speak with leaders in the field of HIV and AIDS. (Source: UNFPA News)
Nigeria: Aids Conference Delegates Seek Asylum in Australia
[Guardian]SOME 25 delegates to an international AIDS conference held in Melbourne last month fear returning home and will seek asylum in Australia, refugee and welfare agencies said Monday. (Source: AllAfrica News: Health and Medicine)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Eritrea: Eritrea's Continued Progress in Combating HIV/Aids
[Fahamu]Eritrea's remarkable success in combating HIV/AIDS is founded upon a multisectoral approach that involves the targeting of harmful societal behaviors and traditions like banning child marriage and female genital cutting (Source: AllAfrica News: HIV-Aids and STDs)
Senegal: Children, the Biggest Losers in Fight Against Aids
[IPS]Dakar -Children living with HIV in Senegal suffer because of the taboo associated with this disease in a country which is, however, praised for its fight against the pandemic. (Source: AllAfrica News: Health and Medicine)
South Africa: Aids Conference Returns to Durban in 2016
[Health-e]The International AIDS Society announced in Melbourne last week that the biennial AIDS conference will return to Durban in 2016. But this time, the circumstances in the country are significantly different than 2000. Last year, only around 7 600 babies were infected with HIV by their mothers, in comparison to 56 000 babies in 2003. (Source: AllAfrica News: HIV-Aids and STDs)
South Africa: Opinion - It's Time We Caught Up to HIV Science
[Health-e]The country's first openly HIV-positive Mr Gay South Africa finalist Charles Jacobs asks, HIV science has changed but have we? The latest court case against the South African National Defense Force (SANDF) may be a sign that we haven't. (Source: AllAfrica News: HIV-Aids and STDs)
Uganda: Male Circumcision Lowers HIV Risk for Women-Study Shows
[Independent]A man being prepared for circumcision.A campaign to promote male circumcision to prevent AIDS infection also indirectly benefits women by reducing their risk of contracting the HIV virus, according to a study presented on July 25 at the world AIDS forum. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Malawi: Chiradzulu DAC Hails World Vision for HIV and Aids Support
[Malawi News Agency]Chiradzulu -The District Aids Coordinator for Chiradzulu, Christopher Nawata has commended Non Governmental Organizations (NGOs) for playing a pivotal role in implementing Prevention of Mother to Child Transmission of HIV initiative in the district. (Source: AllAfrica News: HIV-Aids and STDs)
Africa: Financing Trends and Making Smarter Investments in the HIV Response
[Key Correspondents]During a high-level political session at the 20th International AIDS Conference, UNAIDS executive director Michel Sidibé has called for a new set of treatment targets by 2030. (Source: AllAfrica News: HIV-Aids and STDs)
Tanzania: HIV/Aids Infections Can Be Stopped - UNAIDS
[Daily News]NEW HIV/AIDS infections can be stopped in the country if there is more dialogue and people involvement, UNAIDS Country Coordinator, Dr Patrick Brenny said. (Source: AllAfrica News: HIV-Aids and STDs)
Nigeria Wakes Up to its AIDS Threat
Nigeria accounts for one third of all new infections among children in the 20 worst hit countries in sub-Saharan Africa. Credit: Sam Olukoya/IPSBy Sam OlukoyaLAGOS, Nigeria, Aug 4 2014 (IPS) Tope Tayo?s marriage broke up 11 years ago after she tested positive for HIV. Her angry and embarrassed husband took away their only child. Three months later, when the one year old boy tested positive, the husband dumped him with Tayo and absconded.  ?He abandoned us as if we had committed a crime but I told him HIV is not a crime,? Tayo told IPS. She was jobless and the husband paid no maintenance. ?I walked the streets crying, I was living on charity,? Tayo recalls. The runaway man who abandons his HIV positive wife and children is a common feature in Nigeria, says Rosemary Hua, coordina...
Commentary: Antiretroviral treatment for pregnant and breastfeeding women ? the shifting paradigm: Erratum
No abstract available (Source: AIDS)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Risk of Cancer Among HIV-Infected IndividualsRisk of Cancer Among HIV-Infected Individuals
How much of an impact to immune deficiency and smoking have on cancer risk in HIV+ individuals? AIDS (Source: Medscape Today Headlines)
New idea for hearing improvement in patients with hearing aids under background noise
(Neural Regeneration Research) Patients with implanted artificial cochlea often complain that they cannot recognize speech well in natural environments, especially if background of noise is present. Researchers think that a poor ability to localize sound in a complex auditory environment is responsible for the weak speech perception observed under these conditions. (Source: EurekAlert! - Medicine and Health)
Therapeutic drug monitoring of voriconazole: a case report of multiple drug interactions in a patient with an increased CYP2C19 activity
Conclusion: The integration of drug-drug interactions and pharmacogenetics data is crucial to interpret drug concentrations correctly, thus preventing suboptimal exposure to voriconazole. (Source: AIDS Research and Therapy)
Influence of providers and nurses on completion of non-targeted HIV screening in an urgent care setting
Conclusions: Visit provider and triage nurse were strongly associated with acceptance of testing, which may reflect variable opinions of HIV screening in this setting by clinical staff. Among patients accepting screening, visit provider remained strongly associated with completion of testing. Despite longstanding recommendations for non-targeted HIV screening, further changes to improve the testing and results process, as well as provider education and buy-in, are needed to improve screening rates. (Source: AIDS Research and Therapy)
Representation of Health Conditions on Facebook: Content Analysis and Evaluation of User Engagement
Conclusions: This research represents the first attempts to comprehensively describe publicly available health content and user engagement with health conditions on Facebook pages. Public health interventions using Facebook will need to be designed to ensure relevant information is easy to find and with an understanding that stigma associated with some health conditions may limit the users? engagement with Facebook pages. This line of research merits further investigation as Facebook and other SNS continue to evolve over the coming years. (Source: Journal of Medical Internet Research)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Teaching NeuroImages: Partial Brown-Sequard syndrome: A rare presentation of CMV myelitis
A 53-year-old man with AIDS presented with left leg weakness and right leg numbness. Examination was significant for left lower extremity weakness in a pyramidal pattern (4/5), left knee and ankle hyperreflexia, left Babinski sign, and decreased pain and temperature sensation over right lower extremity extending up the right torso up to T5 dermatome. Vibration and proprioception were normal. Thoracic spine MRI showed hyperintensity in the left hemicord (figure, A and B). CSF analysis showed mild protein elevation with lymphocytic pleocytosis, and positive cytomegalovirus (CMV) PCR, consistent with CMV myelitis. Treatment with gancylcovir1 and foscarnet2 resulted in gradual improvement in the patient's symptoms and examination. (Source: Neurology)
Data Are Key In Care For Patients With HIV/AIDS [Letters]
(Source: Health Affairs)
Cohort Profile: Seek and Treat for the Optimal Prevention of HIV/AIDS in British Columbia (STOP HIV/AIDS BC)
The Seek and Treat for Optimal Prevention of HIV/AIDS (STOP HIV/AIDS) cohort is a census of all identified HIV-positive individuals in the province of British Columbia. It was formed through the linkage of nine provincial treatment, surveillance and administrative databases. This open cohort allows for bidirectional analyses from 1996 onward and is refreshed annually. Extensive data collection for cohort members includes demographic information, detailed clinical and laboratory data, complete prescription drug use including antiretroviral agents, and information on health service utilization encompassing inpatient and outpatient care, addictions treatment and palliative care. This cohort provides an unprecedented opportunity to evaluate, over an extended time period, patterns and determina...
Constrictive Pericarditis Requiring Pericardiectomy at Groote Schuur Hospital in Cape Town, South Africa: Causes and Peri-operative Outcomes in the HIV Era (1990 ? 2012)
This study is the largest on the subject emanating from Africa in the HIV/AIDS era. It highlights the importance of early referral for pericardiectomy in constrictive pericarditis and the safety of surgery in those infected with HIV/AIDS. (Source: The Journal of Thoracic and Cardiovascular Surgery)
Cognitive deficits associated with combined HIV gp120 expression and chronic methamphetamine exposure in mice
Methamphetamine abuse is common among individuals infected by human immunodeficiency virus (HIV). Neurocognitive outcomes tend to be worse in methamphetamine users with HIV. However, it is unclear whether discrete cognitive domains are susceptible to impairment after combined HIV infection and methamphetamine abuse. The expression of HIV/gp120 protein induces neuropathology in mice similar to HIV-induced pathology in humans. We investigated the separate and combined effects of methamphetamine exposure and gp120 expression on cognitive function in transgenic (gp120-tg) and control mice. (Source: European Neuropsychopharmacology)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Structural and community-level interventions for increasing condom use to prevent the transmission of HIV and other sexually transmitted infections.
CONCLUSIONS: There is no clear evidence that structural interventions at the community level to increase condom use prevent the transmission of HIV and other STIs. However, this conclusion should be interpreted with caution since our results have wide confidence intervals and the results for prevalence may be affected by attrition bias. In addition, it was not possible to find RCTs in which extended changes to policies were conducted and the results only apply to general populations in developing nations, particularly to Sub-Saharan Africa, a region which in turn is widely diverse. PMID: 25072817 [PubMed - in process] (Source: Herpes)
Clinical relevance of the plasma load of cytomegalovirus in patients infected with HIV?a survival analysis
ABSTRACT To investigate whether asymptomatic cytomegalovirus (CMV) viraemia impact the course of human immunodeficiency virus (HIV) infection, this study evaluated the effect of CMV replication on progression of newly?diagnosed HIV infected individuals towards AIDS events and death. In a 3?year prospective study on co?infected patients, clinical, immunological, and virological tests were performed in a national reference hospital quarterly. CMV viraemia was quantified by RoboGene® HCMV DNA Quantification Kit (Analytik Jena, Germany), on ABI Prism® 7000 Sequence Detection System (Applied Biosystems, USA). One hundred and five patients were enrolled with a balanced sex distribution and a median age of 30.7?years. Median CD4+ cell count at enrollment was 164/mm3 and median HIV RNA 4...
Africa: Children Living With Aids, That's Where It Hurts the Most
[Key Correspondents]When HIV was discovered in the early 1980s, one shock came after another. First, it is a virus for which there was no cure. Second, it has serious health implications and, before the arrival of antiretroviral therapy, would likely lead to mortality. Finally, most shocking perhaps was the discovery that it was trans-generational, which means babies being born with the virus. (Source: AllAfrica News: HIV-Aids and STDs)
Breaking Open Public Places: UNFPA Launches Coolibah - 21 July 2014
MELBOURNE, Australia &ndash; At the International AIDS Conference 2014 today, UNFPA, the United Nations Population Fund, launched a youth networking zone called the coolibah, where, throughout the week, it will host a range of activities for and with young people, including a series of luncheons with leaders in the field of HIV and AIDS. (Source: UNFPA News)
UNFPA engages young people in the fight against HIV - 21 July 2014
MELBOURNE, Australia &ndash; Every hour, about 80 young people are newly infected with HIV, according to the recently released Gap Report by UNAIDS. The participation and leadership of young people will therefore be critical in bringing the global HIV epidemic to an end. Today, at the 20th International AIDS Conference, UNFPA launched a youth networking zone called the &lsquo;coolibah&rsquo;, where young people will be able to speak with leaders in the field of HIV and AIDS. (Source: UNFPA News)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
The provision of aids and adaptations, risk assessments, and incident reporting and recording procedures in relation to injury prevention for adults with intellectual disabilities: cohort study - Finlayson J, Jackson A, Mantry D, Morrison J, Cooper SA.
BACKGROUND: Adults with intellectual disabilities (IDs) experience a higher incidence of injury, compared with the general population. The aim of this study was to investigate the provision of aids and adaptations, residential service providers' individual... (Source: SafetyLit: All (Unduplicated))
Girls Just Wanna Have Fun: a process evaluation of a female youth-driven physical activity-based life skills program
Conclusions: Overall, this process evaluation represents an important step in responding to calls for increased evaluation in community-based programs and aids in understanding the process in which positive youth development programs can be effectively implemented. (Source: Epidemiologic Perspectives and Innovations)
Increase in condom use and decline in prevalence of sexually transmitted infections among high-risk men who have sex with men and transgender persons in Maharashtra, India: Avahan, the India AIDS Initiative
Conclusion: The current evaluation provides evidence for successful scale up and coverage of target population by Avahan interventions in Maharashtra. The assessment findings showed improved accessibility to condoms and reduced risk behaviours with male sexual partners. Syphilis prevalence declined; however HIV prevalence did not change and is still a major concern. Continued strengthening of core programmatic strategies are needed to effectively improve condom use with all partner types and to help bring sustained reductions in HIV risk in HR-MSM/TG and its onward transmission. (Source: BMC Public Health - Latest articles)
Adherence to antiretroviral therapy in adolescents living with HIV: systematic review and meta-analysis
Conclusion:Review of published literature from Africa and Asia indicate more than 70% of HIV-positive AYA populations receiving ART are adherent to therapy and lower rates of adherence were shown in Europe and North America at 50?60%. The global discrepancy is probably multifactorial reflecting differences between focused and generalised epidemics, access to healthcare and funding. (Source: AIDS)
Engagement-in-Care During the First 5 Years After HIV Diagnosis: Data from a Cohort of Newly HIV-Diagnosed Individuals in a Large US City
AIDS Patient Care and STDs , Vol. 0, No. 0. (Source: AIDS Patient Care and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
[Editorial] Chronic kidney disease: refining diagnosis and management
From 1990 to 2010, deaths from chronic kidney disease (CKD) rose by about 82% worldwide?the third largest increase among the top 25 causes of death after HIV/AIDS (396%) and diabetes (93%). In England, about £1·45 billion was spent on caring for people with CKD in 2009?10, just 1·3% of National Health Service spending, and a substantial proportion of this cost was devoted to renal replacement therapy in the small proportion of patients with kidney failure. In July, the UK's National Institute of Health and Care Excellence (NICE) updated its clinical guideline on CKD, aiming to ensure consistent identification of CKD and thereby improve management. (Source: LANCET)
[Comment] Offline: Ending the AIDS epidemic
There are some articles journal editors will wish they hadn't brought to public attention. But there will also be papers they are immensely grateful to have published. One such Lancet paper is Julio Montaner's truly landmark 2006 viewpoint entitled, rather modestly now looking back, ?The case for expanding access to highly active antiretroviral therapy [HAART] to curb the growth of the HIV epidemic?. The paper began by charting, since its inception in 1996, the rise and impact of HAART. Montaner and his team went on to hypothesise that, ?A prevention-centred approach would therefore argue that treating 100% of HIV-infected individuals at once could greatly reduce HIV transmission. (Source: LANCET)
TLRs: Linking Inflammation and Breast cancer.
Authors: Bhatelia K, Singh K, Singh R Abstract Breast cancer is one of the leading causes of mortality in the females. Intensive efforts have been made to understand the molecular mechanisms of pathogenesis of breast cancer. The physiological conditions that lead to tumorigenesis including breast cancer is not well understood. Toll like receptors (TLRs), are essential component of innate immune system that protects the host against bacterial and viral infection. The emerging evidences suggest that TLRs are activated through pathogen associated molecular patterns (PAMPs) as well as endogenous molecules, which lead to the activation of inflammatory pathways. This leads to increased levels of several pro-inflammatory cytokines and chemokines mounting inflammation. Several evidences su...
Large-Scale HIV Test-and-Treat Strategy ViableLarge-Scale HIV Test-and-Treat Strategy Viable
A large-scale trial in which residents are offered HIV testing and treatment is feasible at a population level. Medscape Medical News (Source: Medscape Today Headlines)
A Randomized Controlled Trial of the Efficacy of a Stigma Reduction Intervention for HIV-Infected Women in the Deep South
AIDS Patient Care and STDs , Vol. 0, No. 0. (Source: AIDS Patient Care and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Hormonal Contraceptives Don't Increase HIV Risk, Study FindsHormonal Contraceptives Don't Increase HIV Risk, Study Finds
Contraceptives Medscape Medical News (Source: Medscape Today Headlines)
'HIV drugs boost' SA life expectancy
Life expectancy in South Africa has increased dramatically over the last decade mainly thanks to life-saving Aids drugs, a government report says. (Source: BBC News | Health | UK Edition)
HIV drugs 'boost SA life expectancy'
Life expectancy in South Africa has increased dramatically over the last decade mainly thanks to life-saving Aids drugs, a government report says. (Source: BBC News | Health | UK Edition)
Africa: View On Migration - Anti-HIV Measures That Cross Borders
[SciDev.Net]Earlier this month, UNAIDS published its annual Gap report, drawing together global data on HIV/AIDS alongside information and analysis about the 'people being left behind' in the fight against the disease. (Source: AllAfrica News: HIV-Aids and STDs)
This won't be AIDS-free generation
He was just 18 years old when he got the news. It was the summer before his senior year in high school. (Source: CNN.com - Health)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Kenya: Tribunal Tackles Aids Discrimination
[Capital FM]Nairobi -Since its establishment in 2009, The HIV and AIDS Tribunal has dealt with 60 cases where people were discriminated for being HIV positive in Kenya. (Source: AllAfrica News: HIV-Aids and STDs)
Breaking Open Public Places: UNFPA Launches Coolibah - 21 July 2014
MELBOURNE, Australia &ndash; At the International AIDS Conference 2014 today, UNFPA, the United Nations Population Fund, launched a youth networking zone called the coolibah, where, throughout the week, it will host a range of activities for and with young people, including a series of luncheons with leaders in the field of HIV and AIDS. (Source: UNFPA News)
UNFPA engages young people in the fight against HIV - 21 July 2014
MELBOURNE, Australia &ndash; Every hour, about 80 young people are newly infected with HIV, according to the recently released Gap Report by UNAIDS. The participation and leadership of young people will therefore be critical in bringing the global HIV epidemic to an end. Today, at the 20th International AIDS Conference, UNFPA launched a youth networking zone called the &lsquo;coolibah&rsquo;, where young people will be able to speak with leaders in the field of HIV and AIDS. (Source: UNFPA News)
Nigeria: Nigeria and the HIV Burden
[Independent]Even as global attention focused more on the tragic shutting down of Malaysian Airline MH17 allegedly by Ukrainian rebels , the World AIDS Conference which held in Melbourne, Australia between 21-25 July was another reflective milestone on a malaise that have threatened human posterity. (Source: AllAfrica News: HIV-Aids and STDs)
Disappearance of Renal Stones in an HIV-1-Infected Patient After Reduction of Atazanavir Dose
AIDS Research and Human Retroviruses , Vol. 0, No. 0. (Source: AIDS Research and Human Retroviruses)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Computer?assisted reading intervention with a phonics approach for children using cochlear implants or hearing aids
The present study examined computer?assisted reading intervention with a phonics approach for deaf and hard of hearing (DHH) children in Sweden using cochlear implants or hearing aids, or a combination of both. The study included 48 children, 5, 6 and 7 years of age. Sixteen children with normal hearing (NH) served as a reference group. The first purpose of the study was to compare NH and DHH children's reading ability at pre and post?intervention. The second purpose was to investigate effects of the intervention. Cognitive and demographic factors were analyzed in relation to reading improvement. Results showed no statistically significant difference for reading ability at the group level, although NH children showed overall higher reading scores at both test points. Age comparisons r...
The RAB5?GEF Function o f RIN1 Regulates Multiple Steps During Listeria monocytogenes Infection
Abstract Listeria monocytogenes is a food?borne pathogenic bacterium that invades intestinal epithelial cells through a phagocytic pathway that relies on activation of host cell RAB5 GTPases. L. monocytogenes must subsequently inhibit RAB5, however, in order to escape lysosome?mediated destruction. Relatively little is known about upstream RAB5 regulators during L. monocytogenes entry and phagosome escape processes in epithelial cells. Here we identify RIN1, a RAS effector and RAB5?directed GEF, as a host cell factor in L. monocytogenes infection. RIN1 is rapidly engaged following L. monocytogenes infection and is required for efficient invasion of intestinal epithelial cells. RIN1?mediated RAB5 activation later facilitates the fusion of phagosomes with lysosomes, promoting clearan...
Impact of community-based interventions on HIV knowledge, attitudes, and transmission
This paper evaluates the impact of community based delivery if interventions on HIV knowledge, attitudes, and transmission. Findings suggest that community based interventions to increase HIV awareness and risk reduction interventions are effective in improving knowledge scores for HIV/AIDS, protected sexual encounters, increased condom use and decreasing frequency of sexual intercourse. Image: Community based delivery of ART for HIV. (Source: Epidemiologic Perspectives and Innovations)
Regional and national guideline recommendations for digital ano-rectal examination as a means for anal cancer screening in HIV positive men who have sex with men: a systematic review
Conclusions: Few HIV guidelines discuss or recommend DARE as a means of anal cancer screening. Studies of the efficacy, acceptability and cost-effectiveness of DARE are needed to assess its role in anal cancer screening. (Source: Epidemiologic Perspectives and Innovations)
[In Depth] Cure setbacks force HIV researchers to reset sights
Remission is seen as a more realistic goal. Author: Jon Cohen (Source: Science: Current Issue)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
The Effects of Parental Loss on the Psychosocial Wellbeing of AIDS-Orphaned Children Living in AIDS-Impacted Communities: Does Gender Matter?
Authors: Nabunya P, Ssewamala FM PMID: 25067869 [PubMed - as supplied by publisher] (Source: Children and Youth Services Review)
In the Routine HIV Testing Era, Primary Care Physicians in Community Health Centers Remain Unaware of HIV Testing Recommendations
Conclusion: With the new 2013 US Preventive Services Task Force recommendations to support routine HIV testing, it is critical to address ongoing physician HIV testing barriers to mitigate the HIV epidemic. (Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC))
Association between Dog Guardianship and HIV Clinical Outcomes
Despite numerous potential health outcomes of dog guardianship, their value has not been examined in the HIV-positive population. The study objective was to examine the relationship between dog guardianship and HIV clinical outcomes (antiretroviral adherence [&ge;95% versus &lt;95%], HIV viral load [&ge;48 versus &lt;48 copies/mL], and CD4 count) among HIV-positive individuals. The authors conducted a secondary analysis of baseline data of 370 HIV-positive men on antiretroviral regimen enrolled in the Duo Project. Generalized estimating equations were used for inferential regression analyses, while controlling for the focal dog guardianship variable and nonfocal covariates. Current dog guardianship was reported in 28.7% of participants. Dog guardianship may be associated with higher CD4 (c...
Religion and HIV/AIDS Stigma in Puerto Rico: A Cultural Challenge for Training Future Physicians
In this study, we documented the association of religion with HIV/AIDS stigma in a sample of medical students in Puerto Rico. Findings suggest that importance placed on religion, and participation in religious activities, is associated with HIV/AIDS stigma for this population. (Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC))
Rhodococcus equi Pericarditis in a Patient Living with HIV/AIDS
We report a case of a 48-year-old male patient with newly diagnosed HIV/AIDS presenting with recurrent R equi bacteremia, pericardial effusion, and pericardial cyst. The infection was treated with drainage of the pericardial effusion and cyst and 2 weeks of intravenous vancomycin and 6 months of oral azithromycin and levofloxacin. Discussion: Rhodococcus equi causes pericarditis and pericardial effusion. It can be effectively treated with debridement, drainage, and a prolonged course of antibiotics. In vitro antibiotic susceptibility should be checked as resistance to antibiotics can develop, especially if drainage is inadequate. (Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC))<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
AIDS-Related Lymphoma: Resolution with Antiretroviral Therapy Alone
We present a case of a female patient with HIV (CD4 count of 576 cells/mm3) diagnosed with a stage III-B non-Hodgkin lymphoma in 2009 while off HAART. She was subsequently started on HAART, leading to full resolution of her lymphoma without any chemotherapeutic intervention. She was last seen in the clinic in December 2013 without any evidence of recurrence of her lymphoma. To our knowledge, this is the first case report of a stage III-B non-Hodgkin lymphoma in an HIV-infected patient, which resolved with only HAART. (Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC))
HIV-Associated Thromboembolic Phenomenon due to Protein C Deficiency
We report a case of a 12-year-old girl with facial palsy due to middle cerebral artery infarct because of HIV infection and associated protein C deficiency. (Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC))
The Effect of Relaxation Interventions on Cortisol Levels in HIV-Seropositive Women
Conclusions: Results suggest that specific relaxation techniques may be partially responsible for cortisol decreases associated with relaxation and CBSM. (Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC))
CD4 Counts in Laboratory Monitoring of HIV Disease--Experience from Western India
Conclusion: The cutoff values of CD4 counts for HIV disease may need to be revised for India. Regular CD4 count estimation is a must for monitoring disease progression in people living with HIV/AIDS. (Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC))
Pain, Sleep Disturbances, and Functional Limitations in People Living with HIV/AIDS-Associated Distal Sensory Peripheral Neuropathy
Conclusions: The data collected suggest that PLWHA-DSPN report moderate-to-severe pain and significant sleep disturbances and exhibit limited ambulation distances. (Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC))<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Group Problem-Solving Therapy for Postnatal Depression among HIV-Positive and HIV-Negative Mothers in Zimbabwe
Postnatal depression (PND) is a major problem in low- and middle-income countries (LMICs). A total of 210 postpartum mothers attending primary care urban clinics were screened for PND at 6 weeks postpartum using the Edinburgh Postnatal Depression Scale (EPDS) and Diagnostic and Statistical Manual of Mental Disorders (Fourth Edition; DSM-IV) criteria for major depression. The HIV prevalence was 14.8%. Of the 210 enrolled postpartum mothers, 64 (33%) met DSM IV criteria for depression. Using trained peer counselors, mothers with PND (n = 58) were randomly assigned to either group problem-solving therapy (PST, n = 30) or amitriptyline (n = 28). Of the 58 mothers with PND, 49 (85%) completed 6 weeks of group PST (n = 27) or pharmacotherapy (n = 22). At baseline, the mean EPDS score for partici...
HIV Provider-Patient Communication Regarding Cardiovascular Risk: Results from the 2010 AIDS Treatment for Life International Survey
Conclusion: We found that HIV clinicians worldwide are not sufficiently addressing CVD risk factors with their patients. Expanded training and education for HIV clinicians should include effective approaches to the mitigation of CV risk factors. (Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC))
The Effect of Depressive Symptoms and CD4 Count on Adherence to Highly Active Antiretroviral Therapy in Sub-Saharan Africa
Conclusions: These results indicate that mental health and clinical parameters are significant factors in determining patients&rsquo; adherence to their HAART, which need to be more aggressively addressed as a critical component of care and treatment support. (Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC))
Ritonavir-Boosted Lopinavir as Maintenance Monotherapy in HIV-Infected Patients Who Achieved Viral Suppression during a Second-Line Protease Inhibitor-Based Regimen: A Pilot Randomized Trial (BIDI-MONO)
Eligibility criteria were (1) having previously failed first-line nonnucleoside reverse transcriptase inhibitor&ndash;based regimens and (2) having achieved virologic suppression &gt;6 months while receiving a protease inhibitor (PI)-based regimen as second-line treatment. Eligible participants were randomized to receive either (1) ritonavir-boosted lopinavir (LPV/r) monotherapy (n = 29) or (2) LPV/r with optimized background regimens (OBRs; n = 31). Median duration of viral suppression before randomization was 45 months. At week 48, viral suppression during LPV/r monotherapy was 86.2% and did not differ from the suppression achieved with LPV/r with OBRs (87.1%, P = 1.000). However, persistent viremia during LPV/r monotherapy tended to be higher than during LPV/r with OBRs (10.3% versus 3....
Evaluation of an HIV Adherence Counseling Program in La Romana, Dominican Republic
Research has demonstrated that adherence to antiretroviral therapy (ART) results in lower rates of morbidity and mortality associated with HIV infection, yet adherence remains a challenge in resource-limited settings like the Dominican Republic. Cl&iacute;nica de Familia La Romana addressed this problem with an education-based adherence program for adult patients new to ART, and this retrospective cohort study aimed to evaluate the impact of this intervention. Appointment adherence and biological markers were assessed in cases and controls through 12 months. A total of 101 participants were included, with 61 controls and 40 cases. The baseline CD4 count was 162 and 157 cells/mm3 in controls and cases, respectively. Cases showed a 15-fold increase in CD4 count compared with a 2.5-fold incre...<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Long-Term Outcome of Second-Line Antiretroviral Therapy in Resource-Limited Settings
There is limited information on efficacy and durability of second-line antiretroviral therapy (2NL) beyond 12 months in resource-limited settings. A total of 73 patients were enrolled into a prospective 2NL observational cohort in Nigeria. Second-line antiretroviral therapy consisted of lopinavir/ritonavir plus nucleoside reverse transcriptase inhibitors. Time on 2NL ranged from 15 to 31 months. Genotypes were retrospectively done and not available to guide second-line regimen choice. At enrollment, median CD4 count was 121 cells/mm3, and median time on first-line antiretroviral therapy (1SL) was 24 months. At 6 to 9 months on 2NL, 72.6% (intention to treat [ITT]) and 88.3% (on treatment [OT]) had an undetectable viral load (UDVL). At 12 months, 65.8% (ITT) and 90.57% (OT) had UDVL. At &gt...
"Notify Your Partners--It's the Law": HIV Providers and Mandatory Disclosure
This study compared provider attitudes and practices in relation to counseling clients about mandatory disclosure in North Carolina and Alabama, the 2 states with similar HIV epidemiology but different laws for HIV control. Personal interviews were conducted with 20 providers in each state (n = 40). The results were analyzed in a qualitative, cross-comparison method to identify patterns of convergence or difference. Providers in both states believed that clients often failed to notify sexual partners and were secretive if questioned about disclosure. Differences in counseling styles and procedures for each state were noteworthy. Compared to Alabama, North Carolina had harsher penalties for nondisclosure, stricter and more standardized procedures for counseling, and providers expressed grea...
Law and Pediatric HIV Testing: Realizing the Right to Health in Kenya
Realization of the right to health occurs along a continuum including national ratification of international treaties such as the Convention on the Rights of the Child, passage of domestic laws and policies that may specify modes of implementation and enforcement such as Kenya&rsquo;s Constitution and HIV and AIDS Prevention and Control Act, and actual implementation of domestic laws and policies such as through the regulation and delivery of health services. The stages heuristic theoretical framework describes the public policy continuum as consisting of marked stages: agenda setting, policy formulation, policy implementation, and evaluation. This case study illustrates the continuum in Kenya with regard to pediatric HIV testing. Kenya has made progress applying law, policy, and science t...
Differential glycosylation of envelope gp120 is associated with differential recognition of HIV-1 by virus-specific antibodies and cell infection
Conclusion: Our data support the hypothesis that the glycosylation machinery of different cells shapes gp120 glycosylation and, consequently, impacts envelope recognition by specific antibodies as well as the interaction of HIV-1 gp120 with cellular receptors. These findings underscore the importance of selection of appropriately glycosylated HIV-1 envelope as a vaccine antigen. (Source: AIDS Research and Therapy)
AIDSinfo HIV/AIDS Awareness Day Widget Now Available
AIDSinfo is pleased to announce the release of our HIV/AIDS Awareness Day widget! Add the widget to your website or blog to display the logos for the national HIV/AIDS awareness days. The logos will link to the AIDSinfo HIV/AIDS awareness day pages. The widget also provides links to the infoSIDA HIV/AIDS awareness day pages.&nbsp; Along with our HIV/AIDS awareness day widget, we also have a widget for our news feed. Add this widget to your website to display the latest HIV/AIDS treatment, prevention, and research news. Instructions for adding the widgets to your website can be found on the AIDSinfo widget page.&nbsp; Questions about our widgets? Please send an e-mail to ContactUs@aidsinfo.nih.gov. (Source: AIDSinfo At-a-Glance: Offering Information on HIV/AIDS Treatment, Prevention, and...<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
News from NIAID
July 24, 2014: Powerful HIV Antibodies May Require Assist from Second Antibody to Develop July 21, 2014: At AIDS 2014, Dr. Anthony S. Fauci Discusses Key Challenges in HIV Scientific Discovery: Cure, Vaccine&nbsp; July 21, 2014: NIH-Supported Scientists Demonstrate Very Early Formation of SIV Reservoir July 19, 2014: HIV Cure Research: Where We Are, Where We Are Headed (Source: AIDSinfo At-a-Glance: Offering Information on HIV/AIDS Treatment, Prevention, and Research, A Service of the U.S. Department of Health and Human Services (DHHS))
Development and preliminary user testing of the DCIDA (Dynamic computer interactive decision application) for 'nudging' patients towards high quality decisions
Conclusion: Preliminary results suggest that DCIDA has potential to improve the quality of patient decision-making. Next steps include larger studies to test individual components of DCIDA and feasibility testing with patients making real decisions. (Source: BMC Medical Informatics and Decision Making - Latest articles)
HIV and Child Mental Health: A Case-Control Study in Rwanda
CONCLUSIONS: The mental health of HIV-affected children requires policy and programmatic responses comparable to HIV-positive children. (Source: PEDIATRICS)
Cost effectiveness of a web-based decision aid for parents deciding about MMR vaccination: a three-arm cluster randomised controlled trial in primary care.
CONCLUSION: The decision aid has a high chance of being cost effective, regardless of the value placed on obtaining additional vaccinations. It also appears to offer an efficient means of decision support for parents. PMID: 25071062 [PubMed - in process] (Source: The British Journal of General Practice)
Direct Anterior versus Miniposterior THA With the Same Advanced Perioperative Protocols: Surprising Early Clinical Results.
CONCLUSIONS: There was no systematic advantage of direct anterior THA versus miniposterior THA. Contrary to conventional belief and somewhat surprising were the fewer minor wound problems in the direct anterior group and the higher proportion of patients free of gait aids at 2 weeks and back to driving and working at 8 weeks in the miniposterior group. Factors other than surgical approach, perhaps including attentive pain management, patient selection, surgical volume and experience, careful preoperative templating, and rapid rehabilitation protocols, may be more important in terms of influencing early recovery after THA. LEVEL OF EVIDENCE: Level III, therapeutic study. See Instructions for Authors for a complete description of levels of evidence. PMID: 25082624 [PubMed - as supp...<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Increased costs of HIV care associated with aging in an HIV?infected population
ConclusionsThe aging of the HIV?infected population in care is leading to increased HIV care costs. Health care planners and funding agencies need to be aware of the impact of this important shift in HIV demographics on the overall costs of HIV care. (Source: HIV Medicine)
[Osteogenesis imperfecta].
Authors: Salzmann M, Krohn C, Berger N Abstract BACKGROUND: Osteogenesis imperfecta (OI) is the most common genetic disease of bone and is characterized by fragile bones and growth disorders of varying severity. Most cases of OI are inherited autosomal dominant and caused by a mutation in the collagen type I gene. DIAGNOSTICS: Indications for OI are bone fragility, stunted growth, scoliosis, skull deformities, blue sclera, loss of hearing, dentinogenesis imperfecta and increased laxity of ligaments and skin. In most cases it is possible to make a clinical diagnosis but a skin biopsy or genetic testing can be useful; however, negative results for these tests do not exclude OI. THERAPY: Therapy must be carried out in a multidisciplinary team and includes conservative (e.g. ph...
Information and decision?making needs among people with mental disorders: a systematic review of the literature
ConclusionsThis review reveals that patients with schizophrenia and depression show extensive information and decision?making needs. The identified needs can initially inform the design of PtDAs for schizophrenia and depression. However, there is an urgent need to investigate information and decision?making needs among patients with other mental disorders. (Source: Health Expectations)
The provision of aids and adaptations, risk assessments, and incident reporting and recording procedures in relation to injury prevention for adults with intellectual disabilities: cohort study
ConclusionMore work is needed to better understand, and more fully incorporate, best practice injury prevention measures into routine support planning for adults with IDs within a positive risk?taking and risk reduction framework. (Source: Journal of Intellectual Disability Research)
Africa: New Tools Released to Help Countries Put Women and Girls At the Center of Their Concept Notes
[GFO]A failure to integrate gender-specific interventions has resulted in concept notes being returned to some countries (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Lessons Learned from the Conduct of a Multisite Cluster Randomized Practical Trial of Decision Aids in Rural and Suburban Primary Care Practices
Reports on participant recruitment for a community-based primary care practice study that included rural clinics. Discusses lessons learned related to timing and location of recruitment and impact of recruitment methods on the intervention implementation. Also describes how the study was designed to minimize disruption for the participating clinical sites. -- (Source: Rural publications via the Rural Assistance Center)
Wnt/?-catenin aids in regulating the proliferation of hepG2 cells mediated by thy-1.
Authors: Cheng BQ, Jiang Y, Zhu Q, Lin WG Abstract Cancer stem cells have been found to play important roles in carcinoma. Although thy-1 has been identified as a potential stem cell marker of liver cancer, whether the Wnt/?-catenin signaling pathway plays an important role in regulating hepatocarcinoma proliferation and apoptosis mediated by thy-1 remains unknown. Our results showed that high thy-1 expression caused hepG2 cells transfected with a pReceiver-M29/thy-1 eukaryotic expression vector to exhibit obvious heteromorphism, featuring double or multiple nuclei and weaker apoptosis. A high expression of ?-catenin, as a critical signaling protein of Wnt/?-catenin, and its downstream transcription factor, cyclinD1, were detected in transfected hepG2 cells. We also used aspirin...
Localization of Productively Infected Cells in the Spleen and Peyer's Patches of Rhesus Macaques During Acute Infection with SIVmac239?nef-Enhanced Green Fluorescent Protein
AIDS Research and Human Retroviruses Aug 2014, Vol. 30, No. 8: 738-739. (Source: AIDS Research and Human Retroviruses)
Interleukin-23 Promotes Interferon-? Responsiveness in Hepatitis C Virus/HIV-Coinfected Patients
AIDS Research and Human Retroviruses Aug 2014, Vol. 30, No. 8: 775-782. (Source: AIDS Research and Human Retroviruses)
Short Communication: Prospective Comparison of Qualitative Versus Quantitative Polymerase Chain Reaction for Monitoring Virologic Treatment Failure in HIV-Infected Patients
AIDS Research and Human Retroviruses Aug 2014, Vol. 30, No. 8: 827-829. (Source: AIDS Research and Human Retroviruses)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Short Communication: Effects of Omega-3 Fatty Acids on Triglycerides and High-Density Lipoprotein Subprofiles in HIV-Infected Persons with Hypertriglyceridemia
AIDS Research and Human Retroviruses Aug 2014, Vol. 30, No. 8: 800-805. (Source: AIDS Research and Human Retroviruses)
Short Communication: Serum-Based Assay Accurately Detects Single Nucleotide Polymorphisms of IL28B and SOCS3 in HIV/Hepatitis C Virus-Coinfected Subjects
AIDS Research and Human Retroviruses Aug 2014, Vol. 30, No. 8: 792-795. (Source: AIDS Research and Human Retroviruses)
Short Communication: East Meets West: A Description of HIV-1 Drug Resistance Mutation Patterns of Patients Failing First Line Therapy in PEPFAR Clinics from Uganda and Nigeria
AIDS Research and Human Retroviruses Aug 2014, Vol. 30, No. 8: 796-799. (Source: AIDS Research and Human Retroviruses)
Short Communication: Molecular Epidemiology of HIV Type 1 Infection in Kazakhstan: CRF02_AG Prevalence Is Increasing in the Southeastern Provinces
AIDS Research and Human Retroviruses Aug 2014, Vol. 30, No. 8: 769-774. (Source: AIDS Research and Human Retroviruses)
Breaking Open Public Places: UNFPA Launches Coolibah - 21 July 2014
MELBOURNE, Australia &ndash; At the International AIDS Conference 2014 today, UNFPA, the United Nations Population Fund, launched a youth networking zone called the coolibah, where, throughout the week, it will host a range of activities for and with young people, including a series of luncheons with leaders in the field of HIV and AIDS. (Source: UNFPA News)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
UNFPA engages young people in the fight against HIV - 21 July 2014
MELBOURNE, Australia &ndash; Every hour, about 80 young people are newly infected with HIV, according to the recently released Gap Report by UNAIDS. The participation and leadership of young people will therefore be critical in bringing the global HIV epidemic to an end. Today, at the 20th International AIDS Conference, UNFPA launched a youth networking zone called the &lsquo;coolibah&rsquo;, where young people will be able to speak with leaders in the field of HIV and AIDS. (Source: UNFPA News)
South Africa: Cosatu Condemns SANDF's Discrimination Against People With HIV
[COSATU]The Congress of South African Trade Unions is shocked that the SA National Defence Force has cancelled the contracts of two women recruits because they tested HIV-positive. They have challenged the decision and taken the SANDF to court. The judge's verdict is awaited. (Source: AllAfrica News: HIV-Aids and STDs)
Nigeria: Women Affairs Ministry to Partner USAID, NACA On GBV, HIV/Aids
[Nigerian Govt]The Federal Ministry of Women Affairs and Social Development is to partner with the United States Agency for International Development (USAID) and the National Agency for Control of AIDS (NACA) in the fight against the growing cases of Gender - Based Violence (GBV) and HIV/AIDS in the country. (Source: AllAfrica News: HIV-Aids and STDs)
Hearing Aids Market Analysis by Product (Behind-The-Ear Aids,...
Market Size - $4,369.3 mn in 2013, Market Growth ? CAGR of 3.2%, Market Trends ? Rapidly growing adoption rates of 100% digital hearing aid technology. View full report with TOC -...(PRWeb July 30, 2014)Read the full story at http://www.prweb.com/releases/Hearing_Aids_Market_Size/Industry_Trends_Analysis/prweb12058370.htm (Source: PRWeb: Medical Pharmaceuticals)
Repeat Antenatal HIV Testing in the Third TrimesterRepeat Antenatal HIV Testing in the Third Trimester
Should a repeat HIV test be performed in the third-trimester of pregnancy? HIV Medicine (Source: Medscape Today Headlines)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Africa: The 'Sex-On-Site' Venues Tour - Queer Melbourne's Erotic Otherworld
[Daily Maverick]Picture going on a tour of venues where people go specifically to have sex. Usually with strangers. In all kinds of unusual ways. But, it seems, whatever they're doing, they're awfully hygienic about it. Seem like an unusual way to spend a morning? REBECCA HODES actually did it. The tour, that is. Strictly business. (Source: AllAfrica News: HIV-Aids and STDs)
Mozambique: First Lady Begins Working Visit to Zambezia
[AIM]Quelimane, Mozambique -Mozambican First Lady Maria da Luz Guebuza on Monday arrived in Quelimane, the provincial capital of Zambezia, at the beginning of a two day working visit. (Source: AllAfrica News: HIV-Aids and STDs)
Functional assessment of multivessel coronary artery disease: ischemia-guided percutaneous coronary intervention
Invasive evaluation and treatment of coronary artery disease (CAD) has traditionally been based upon coronary angiography to determine the need for and the success of revascularization. However, coronary angiography augmented with fractional flow reserve (FFR) creates a paradigm shift, providing a more complete functional assessment of coronary lesions. Measuring FFR to identify ischemic lesions and guide revascularization results in fewer adverse outcomes, including persistent angina, myocardial infarction, and mortality. An ischemic lesion identified by FFR is more likely to lead to adverse events when compared with an angiographically similar lesion with nonischemic FFR when both are treated medically. Although the mechanism explaining this is unclear, it is likely multifactorial, inclu...
Elizabeth Glaser Pediatric AIDS Foundation partners with Riders for Health in Malawi
(Elizabeth Glaser Pediatric AIDS Foundation) Today the Elizabeth Glaser Pediatric AIDS Foundation and Riders for Health announced a new partnership that will expedite the delivery of laboratory samples and HIV-related test results to health facilities in two districts of the Northern and Central Zones of Malawi. (Source: EurekAlert! - Medicine and Health)
Bonga Update
Habari zenu? (How are you?) This past week in Bonga, we?ve been busier than ever. We started teaching at the government schools ¬¬? Bonga Secondary School and Bonga Primary School. We finished our curriculum at Hayatul Islamic Secondary School. Not only did we meet with each form for the last time, we also started a Peer Education club. This club is supposed to continue teaching fellow students and their local community about HIV and AIDS. We prepared them to take on this task during their orientation that consisted of making a constitution, voting for officers and doing practice teachings. When we return from break, we will watch their final teachings and hold a mini graduation ceremony. The week at Hayatul ended with our first testing day ¬? we brought a mobile testing unit to t...<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
The Latest from Haraa
In conclusion, there was absolutely no shortage of good times here in Haraa this week. Slowly slowly we&#8217;re becoming less mzungu, and Haraa is coming to feel more and more like home. We couldn&#8217;t feel more grateful for the chance to share with and learn from this community! Hannah B., Kelsey, Olivia, Elizabeth, and Rashidi The post The Latest from Haraa appeared first on Support For International Change. (Source: Support for International Change : HIV AIDS)
More from Team Himiti!
The Himiti team had a busy week of teaching and prepping for our village-wide testing day. We finally got to teach in our primary school, which included students and even their teachers. We thought it was important that the teachers knew about HIV/AIDS so that they can continue to educate their students after we leave. We also had the opportunity to teach in a variety of village social groups and even some random places where large groups of people were gathered and willing to listen to us. Thursday was spent entirely dedicated to prepping for our test day, the day in which any member of the village will have the opportunity to find out their HIV status through tests provided by SIC. We split up into three groups and headed to each of the sub-villages where we handed out flyers, put up pos...
Global burden, distribution, and interventions for infectious diseases of poverty
This paper aims to review the disease burden, distribution, existing interventions, and coverage for the prevention and control of IDoPs (including NTDs, malaria, TB, and HIV/AIDS), and is followed by a series of papers evaluating the effectiveness of community delivered interventions for the prevention and control of each IDoP. Image: Community based delivery of Interventions for IDoP. (Source: BioMed Central)
HIV-1 Infection Activates the NLRP3 Inflammasome [Microbiology]
We report here that HIV-1 infection in human monocytes efficiently induced IL-1? expression and inflammasome activation. Toll-like receptor 8 (TLR8) was required for inducing pro-IL-1? expression, whereas the NLRP3 inflammasome was required for IL-1? maturation and release. Furthermore, the lysosomal protease cathepsin B and HIV-1 induced production of reactive oxygen species were critical for HIV-induced inflammasome activation and IL-1? production. HIV-1 entry, reverse transcription, and integration were all required for both pro-IL-1? expression and inflammasome activation. Finally, we show that HIV-1-derived RNA was sufficient to induce both pro-IL-1? expression and inflammasome activation. We conclude that HIV-1 infection induced the expression of pro-IL-1? via TLR8-mediated me...
Antigay Laws Already Having a Negative Effect on HealthAntigay Laws Already Having a Negative Effect on Health
The criminalization of same-sex behavior around the world is having a negative effect on health in high-risk HIV groups, including men who have sex with men. Medscape Medical News (Source: Medscape Medical News Headlines)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Kenya: HIV Funding Worries in Kenya
[IRIN]Kisumu/Nairobi -The US President's Emergency Plan for Aids Relief (PEPFAR), the biggest funder of HIV programmes in Kenya, is set to significantly scale down its funding, a move activists and government officials believe could negatively affect the country's fight against the disease. (Source: AllAfrica News: HIV-Aids and STDs)
Nigeria: Ebola Virus Deadlier Than HIV/Aids - Experts
[Leadership]Ebola virus is the most difficult health challenge confronting the third world countries and is deadlier than HIV/AIDs,medical experts have declared. (Source: AllAfrica News: HIV-Aids and STDs)
Zimbabwe: Teenagers Produce HIV,Aids Film
[The Herald]Three teenagers Simbarashe Moyana, Josh Chikosha and Frankson Chikosha have embarked on an HIV and AIDS awareness campaign through a film titled "The Seed of Life" that is set to premiere next month. In an interview Moyana who is one of the producers of the film said different issues affecting the society inspired them to have the production. (Source: AllAfrica News: HIV-Aids and STDs)
Nigeria: HIV/Aids - Ogun Falls Below National Prevalence Average
[Independent]Abeokuta -The recent National HIV/AIDS Reproductive and Health Survey (NARHS) report has identified Ogun State as being below the national average of HIV infections with a prevalence rate of 0.6 per cent. (Source: AllAfrica News: HIV-Aids and STDs)
Breaking Open Public Places: UNFPA Launches Coolibah - 21 July 2014
MELBOURNE, Australia &ndash; At the International AIDS Conference 2014 today, UNFPA, the United Nations Population Fund, launched a youth networking zone called the coolibah, where, throughout the week, it will host a range of activities for and with young people, including a series of luncheons with leaders in the field of HIV and AIDS. (Source: UNFPA News)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
UNFPA engages young people in the fight against HIV - 21 July 2014
MELBOURNE, Australia &ndash; Every hour, about 80 young people are newly infected with HIV, according to the recently released Gap Report by UNAIDS. The participation and leadership of young people will therefore be critical in bringing the global HIV epidemic to an end. Today, at the 20th International AIDS Conference, UNFPA launched a youth networking zone called the &lsquo;coolibah&rsquo;, where young people will be able to speak with leaders in the field of HIV and AIDS. (Source: UNFPA News)
Coreceptor Usage, Diversity, and Divergence in Drug-Naive and Drug-Exposed Individuals from Malawi, Infected with HIV-1 Subtype C for More Than 20 Years
AIDS Research and Human Retroviruses , Vol. 0, No. 0. (Source: AIDS Research and Human Retroviruses)
Erratum
Conclusion: The integrative review allowed to point important questions to be addressed in preventive actions by the health professional, including the nurse, to create a space that works with risk conditioning factors in adolescents for mental health aggravation.?Identificar los factores de riesgo asociados a los problemas de salud mental en adolescentes. Método: Se realizó una revisión integradora de artículos publicados entre los años 2007 y 2013 en cuatro bases de datos. Para la búsqueda de artículos, se utilizaron los descriptores: Salud Mental y Adolescencia, conforme a las bases DeCS/MeSH. Resultados: Se encontraron publicaciones en diferentes revistas, en distintos campos de conocimiento, siendo más frecuentes las investigaciones cuantitativas. Los problemas en salud ment...
Reliability and Reproducibility of Several Methods of Arthroscopic Assessment of Femoral Tunnel Position During Anterior Cruciate Ligament Reconstruction
To assess interobserver and intraobserver agreement of estimating anterior cruciate ligament (ACL) femoral tunnel positioning arthroscopically using circular and linear (noncircular) estimation methods and to determine whether overlay template visual aids improve agreement. (Source: Arthroscopy)
New Tuberculosis Regimen Works Faster, Costs LessNew Tuberculosis Regimen Works Faster, Costs Less
The new once-daily oral regimen known as PaMZ appears to work on both drug-sensitive and multidrug-resistant tuberculosis. Medscape Medical News (Source: Medscape Medical News Headlines)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Digital Reading System Assists Vision Impaired to Read Graphs
People who are blind can now read more than just words, such as graphs and graphics, following the development of an affordable digital reading system by Curtin University researchers. (Source: Disabled World)
Nearly half of Albuquerque health care workers do not have a bachelor?s degree, study says
Nearly half the health care jobs in the Albuquerque metropolitan area are held by pre-baccalaureate workers, or those without a bachelor?s degree, and those workers are the fastest-growing segment of the health care industry, according to a study by the Brookings Institution. Those workers are concentrated in 10 jobs, including nurses, home health aids, medical and dental assistants and emergency medical technicians and paramedics, and many have seen large increases in earnings since 2000, Brookings? (Source: bizjournals.com Health Care:Hospitals headlines)
A Polyvalent Clade B Virus-Like Particle HIV Vaccine Combined with Partially Protective Oral Preexposure Prophylaxis Prevents Simian?Human Immunodeficiency Virus Infection in Macaques and Primes for Virus-Amplified Immunity
AIDS Research and Human Retroviruses , Vol. 0, No. 0. (Source: AIDS Research and Human Retroviruses)
Uptake and Repeat Use of Postexposure Prophylaxis in a Community-Based Clinic in Los Angeles, California
AIDS Research and Human Retroviruses , Vol. 0, No. 0. (Source: AIDS Research and Human Retroviruses)
Prevalence and Virologic Consequences of Transmitted HIV-1 Drug Resistance in Uganda
AIDS Research and Human Retroviruses , Vol. 0, No. 0. (Source: AIDS Research and Human Retroviruses)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Technology: Disrupting Disaster Response since 1881
By Dom Tolli, Preparedness, Health and Safety Services Back in 1881, the American Red Cross used the telegraph for the first time to transmit disaster information during a forest fire in Michigan. I have hunch that someone at the time probably thought the telegraph was fad and that only ?the young people? were into it. Little did anyone know it would launch the Red Cross -and the nation &#8211; onto a path of using technology to help during disasters. Since 1881, the Red Cross has made a paradigm shift in how it distributes information to the public in times of crisis. Instead of distributing millions of brochures and flyers with emergency we now issue millions of mobile alerts and our apps have more than 100 million mobile views. Now, mobile technology is bringing the White House, th...
Study: iPad-based HIV prevention game increased adolescents? knowledge of the disease
Children who played iPad-based HIV prevention game PlayForward: Elm City Stories knew more about HIV risk than those that played other video games, according to an oral abstract on a randomized control trial of 198 adolescents presented at the AIDS conference this week. The mean age of children in this trial was 13. The NIH-funded video game was developed [&#8230;] (Source: mobihealthnews)
Africa: Heightened HIV Risk for People With Disabilities
[IRIN]Melbourne -Inaccessible health services for people with disabilities (PWD), combined with social stigma and violence, contribute to high HIV risk - a gap that must be filled if the disabled are not to remain disproportionately vulnerable to HIV/AIDS, say health experts and activists. (Source: AllAfrica News: HIV-Aids and STDs)
Kenya: BD & PEPFAR Launch Multi-Year Labs for Life Initiative in Kenya
[U.S. Embassy Nairobi]Nairobi, Kenya -Program Focuses on Strengthening Healthcare Systems, Starting with Accreditation for 10 Laboratories (Source: AllAfrica News: HIV-Aids and STDs)
Breaking Open Public Places: UNFPA Launches Coolibah - 21 July 2014
MELBOURNE, Australia &ndash; At the International AIDS Conference 2014 today, UNFPA, the United Nations Population Fund, launched a youth networking zone called the coolibah, where, throughout the week, it will host a range of activities for and with young people, including a series of luncheons with leaders in the field of HIV and AIDS. (Source: UNFPA News)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
UNFPA engages young people in the fight against HIV - 21 July 2014
MELBOURNE, Australia &ndash; Every hour, about 80 young people are newly infected with HIV, according to the recently released Gap Report by UNAIDS. The participation and leadership of young people will therefore be critical in bringing the global HIV epidemic to an end. Today, at the 20th International AIDS Conference, UNFPA launched a youth networking zone called the &lsquo;coolibah&rsquo;, where young people will be able to speak with leaders in the field of HIV and AIDS. (Source: UNFPA News)
Zimbabwe: HIV Status Does Not Affect Eligibility for Pension
[The Herald]Can an HIV positive person qualify for a pension? This was a questioned that was asked by one correspondent who claims to have contributed to the NSSA national pension scheme from 1994 to 2007. (Source: AllAfrica News: HIV-Aids and STDs)
Southern Africa: HIV and Aids Threat to SADC Development
[The Herald]AS leaders from the region gather for the 34th Sadc Summit in Victoria Falls next month, they must seriously reflect on the devastating effect of the HIV and Aids pandemic that is threatening to decimate entire populations. (Source: AllAfrica News: HIV-Aids and STDs)
Rwanda: Circumcision Yields Results as Ebola Threatens
[New Times]A new study by the University of Illinois indicates that circumcised men do not only lower chances of getting HIV by 60% but also are less likely to engage in unprotected sex. (Source: AllAfrica News: HIV-Aids and STDs)
Nigeria: HIV Infection No Longer On the Rise in Nigeria - Idoko
[Leadership]The fear of HIV/AIDS, that debilitating disease, remains the beginning of wisdom for everyone. A recent report that HIV infection was on the increase in the country was not well received. But in this interview with WINIFRED OGBEBO, the director-general, National Agency for the Control of AIDS (NACA), Prof. John Idoko debunks such claim, while giving reports of the activities of the agency (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
South Africa: Sex Workers Demand Representation On District Aids Council
[Health-e]Sex workers are asking for representation on the Northern Cape's John Taolo Gaetsewe District AIDS Council as sex work soars in local mining community. (Source: AllAfrica News: Health and Medicine)
New partnership to improve access to essential pain medications for people living with HIV
(Elizabeth Glaser Pediatric AIDS Foundation) Today the Elizabeth Glaser Pediatric AIDS Foundation and the American Cancer Society announced a new partnership to improve access to essential pain medications for people living with HIV in Swaziland. As part of ACS' Treat the Pain initiative, this new partnership will help improve efforts to better integrate pain management into HIV/AIDS services throughout the country. (Source: EurekAlert! - Cancer)
Do Decision Aids Help Patients Make Difficult Choices? (CME/CE)
(MedPage Today) -- Decision aids designed to help patients make general healthcare choices, such as selecting a treatment location, provide some help, but condition-specific aids may provide the most useful information for patients and families. (Source: MedPage Today Cardiovascular)
Sticking to minimum standards: implementing antibiotic stewardship in intensive care
ConclusionA systematic approach to quality improvement combined with the implementation of a tailored, multi?faceted intervention can improve antimicrobial prescribing practices. (Source: Internal Medicine Journal)
Charakteristika und Koinfektionen mit Syphilis bei neu mit HIV diagnostizierten Patienten aus dem Universitätsklinikum Dresden von 1987?2012
Zusammenfassung HintergrundKoinfektionsraten von HIV und Syphilis sind über Meldedaten nicht erhältlich und es existiert in Ostdeutschland bisher kein Kollektiv, an dem dies repräsentativ für eine Region ermittelt wurde. Steigende Syphilis?Inzidenzraten 2010?2012 besonders bei Männern mit sexuellen Kontakten zu Männern (MSM) werden als Mitursache für die in dieser Gruppe aktuell wieder steigenden HIV?Neuinfektionsraten diskutiert. Patienten und MethodikDie Charakteristika von 355 konsekutiven, neu mit HIV diagnostizierten Patienten aus dem Universitätsklinikum Dresden von 1987?2012 wurden retrospektiv anhand der Meldedaten für den Dresdner Raum und im Vergleich zu bundesweiten Daten überprüft sowie Koinfektionen mit Syphilis analysiert. ErgebnisseIn unserem Kollektiv fan...<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
HCV RNA viral load is independent from CD4 cell count and plasma HIV RNA viral load in immunocompetent HIV-HCV co-infected patients: a 3-years follow-up study
Conclusions: The HCV RNA load, a known pretreatment predictor of response to antiviral therapy, was independent of the two main parameters of HIV disease, plasma HIV RNA and CD4 cell count, over an observation time of 3 years in patients with recovered or spontaneously maintained immunocompetence. (Source: AIDS Research and Therapy)
Decision Aids for Advance Care Planning: An Overview of the State of the Science.
Authors: Butler M, Ratner E, McCreedy E, Shippee N, Kane RL Abstract Advance care planning honors patients' goals and preferences for future care by creating a plan for when illness or injury impedes the ability to think or communicate about health decisions. Fewer than 50% of severely or terminally ill patients have an advance directive in their medical record, and physicians are accurate only about 65% of the time when predicting patient preferences for intensive care. Decision aids can support the advance care planning process by providing a structured approach to informing patients about care options and prompting them to document and communicate their preferences. This review, commissioned as a technical brief by the Agency for Healthcare Research and Quality Effective Health ...
Pain anxiety and negative outcome expectations for activity: Negative psychological profiles differ between the inactive and active
Conclusion: Identifying differences in negative psychological factors aids in the understanding of differential adherence between activity groups and highlights possible factors to change in future intervention research. © 2014 American College of Rheumatology. (Source: Arthritis Care and Research)
Breaking Open Public Places: UNFPA Launches Coolibah - 21 July 2014
MELBOURNE, Australia &ndash; At the International AIDS Conference 2014 today, UNFPA, the United Nations Population Fund, launched a youth networking zone called the coolibah, where, throughout the week, it will host a range of activities for and with young people, including a series of luncheons with leaders in the field of HIV and AIDS. (Source: UNFPA News)
UNFPA engages young people in the fight against HIV - 21 July 2014
MELBOURNE, Australia &ndash; Every hour, about 80 young people are newly infected with HIV, according to the recently released Gap Report by UNAIDS. The participation and leadership of young people will therefore be critical in bringing the global HIV epidemic to an end. Today, at the 20th International AIDS Conference, UNFPA launched a youth networking zone called the &lsquo;coolibah&rsquo;, where young people will be able to speak with leaders in the field of HIV and AIDS. (Source: UNFPA News)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Cerebral microsporidiosis manifesting as progressive multifocal leukoencephalopathy in an HIV-infected individual - a case report.
This report underscores the need for physicians to consider microsporidiosis (potentially affecting the brain) when no other etiology is established both in HIV, non-HIV immunosuppressed patients and in immunocompetent individuals. PMID: 25057277 [PubMed] (Source: AIDS Research and Therapy)
Holla from Njeku!
Njeku, a small but beautiful village nestled in a valley at the base of Sakila Mountain. While our time here has been short, the past week has shown great promise for our impact to be anything but small. The village leaders have been helpful, and it seems that most of the people we come across now recognize us as more than just those new visitors in town. As always, Sunday is a great day for worship, and we used this to our advantage. Understanding our mission, the VEO (Village Executive Officer) kindly sent out letters to the various village churches so that they would mention our testing day during their announcements section of their service. The church we have attended for the past two weeks once again welcomed us with open arms. More than others, it seems they have truly accepted us i...
Mambo from the Sakila crew!
This week we finally started teaching in schools, which has been absolutely incredible. We finally feel like we?re doing what we set out to do. In Sakila, we have two primary schools and two secondary schools, and each teaching has been accompanied by unique challenges. We?ll cover a few of the most interesting occurrences here. Our first teaching was Wednesday (July 9th) afternoon at Sakila Secondary School. When we talked to the headmaster, we were told there would be between 50 and 70 students in each Form (grade), but when we showed up, many students had yet to pay their school fees and we ended up teaching classes of 15. This meant we taught our most important lesson to less than half of the student body, which was disappointing. Regardless, this worked as a good trial run to work...
Early Antiretrovirals Shrink HIV Reservoir in NewbornsEarly Antiretrovirals Shrink HIV Reservoir in Newborns
Evidence continues to support starting antiretrovirals immediately after birth to reduce HIV reservoir size and suppress the virus over the long term. Medscape Medical News (Source: Medscape Medical News Headlines)
Ghana: Rape Victim Demands HIV Test of Doctor
[Ghanaian Chronicle]The Tema Regional office of the Domestic Violence and Victim Support Unit (DOVVSU), is investigating a medical doctor for allegedly raping a 22-year-old student. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Breaking Open Public Places: UNFPA Launches Coolibah - 21 July 2014
MELBOURNE, Australia &ndash; At the International AIDS Conference 2014 today, UNFPA, the United Nations Population Fund, launched a youth networking zone called the coolibah, where, throughout the week, it will host a range of activities for and with young people, including a series of luncheons with leaders in the field of HIV and AIDS. (Source: UNFPA News)
UNFPA engages young people in the fight against HIV - 21 July 2014
MELBOURNE, Australia &ndash; Every hour, about 80 young people are newly infected with HIV, according to the recently released Gap Report by UNAIDS. The participation and leadership of young people will therefore be critical in bringing the global HIV epidemic to an end. Today, at the 20th International AIDS Conference, UNFPA launched a youth networking zone called the &lsquo;coolibah&rsquo;, where young people will be able to speak with leaders in the field of HIV and AIDS. (Source: UNFPA News)
Nigeria: Report Scores Nigeria Low on HIV/Aids Control
[Guardian]CHUKWUMA MUANYA writes on a new global report which points to slow progress in the fight against HIV/AIDS in Nigeria (Source: AllAfrica News: HIV-Aids and STDs)
Africa: Clinton Says Aids-Free Generation 'Within Reach'
[AlertNet]Melbourne -An AIDS-free generation is within reach if early treatment is provided to people infected with HIV and help scaled up for women and children, former U.S. president Bill Clinton said on Wednesday. (Source: AllAfrica News: Health and Medicine)
Kenya: Circumcised Men Not Using Condoms
[The Star]Most men are likely to engage in unprotected sex after being circumcised. A study presented at the 20th International Aids conference indicated that circumcised men don't use condoms owing to the perception that they are at a lower risk of getting HIV. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Routine HIV Screening in New York City and New OrleansRoutine HIV Screening in New York City and New Orleans
This report describes novel HIV screening programs at two urban health care settings, one in New York City and one in New Orleans. Might they serve as models that could be adapted by other facilities? Morbidity & Mortality Weekly Report (Source: Medscape Today Headlines)
Locomotor Functions Over Time in HIV-Infected PatientsLocomotor Functions Over Time in HIV-Infected Patients
How does motor function over time in HIV+ individuals compare with healthy individuals? AIDS (Source: Medscape Today Headlines)
Hoped-for 'AIDS cure' drug fails miserably in monkey experiments; HIV outwits Big Pharma yet again
(NaturalNews) A monkey version of the HIV virus can outwit anti-AIDS drugs just days after entering the body, according to researchers who were disappointed that Big Pharma still cannot produce a human cure for the disease.If the same thing is true for humans, treatment for HIV... (Source: NaturalNews.com)
Kenya: Organization Wants Prostitution Legalized.
[The Star]Sex workers want prostitution legalized so that the country benefits from donor funding. Activist Peninah Mwangi says the government can in turn use the money to carry out HIV/AIDS sensitization campaigns, purchase ARVs and carry out empowerment programmes for sex workers. (Source: AllAfrica News: HIV-Aids and STDs)
Featured in NEJM Journal Watch: Really Rapid Review ? AIDS 2014, Melbourne (FREE)
By the NEJM Journal Watch Editors In his blog HIV and ID Observations, ? (Source: Physician's First Watch current issue)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Breaking Open Public Places: UNFPA Launches Coolibah - 21 July 2014
MELBOURNE, Australia &ndash; At the International AIDS Conference 2014 today, UNFPA, the United Nations Population Fund, launched a youth networking zone called the coolibah, where, throughout the week, it will host a range of activities for and with young people, including a series of luncheons with leaders in the field of HIV and AIDS. (Source: UNFPA News)
UNFPA engages young people in the fight against HIV - 21 July 2014
MELBOURNE, Australia &ndash; Every hour, about 80 young people are newly infected with HIV, according to the recently released Gap Report by UNAIDS. The participation and leadership of young people will therefore be critical in bringing the global HIV epidemic to an end. Today, at the 20th International AIDS Conference, UNFPA launched a youth networking zone called the &lsquo;coolibah&rsquo;, where young people will be able to speak with leaders in the field of HIV and AIDS. (Source: UNFPA News)
Breaking Open Public Places: UNFPA Launches Coolibah - 21 July 2014
MELBOURNE, Australia &ndash; At the International AIDS Conference 2014 today, UNFPA, the United Nations Population Fund, launched a youth networking zone called the coolibah, where, throughout the week, it will host a range of activities for and with young people, including a series of luncheons with leaders in the field of HIV and AIDS. (Source: UNFPA News)
UNFPA engages young people in the fight against HIV - 21 July 2014
MELBOURNE, Australia &ndash; Every hour, about 80 young people are newly infected with HIV, according to the recently released Gap Report by UNAIDS. The participation and leadership of young people will therefore be critical in bringing the global HIV epidemic to an end. Today, at the 20th International AIDS Conference, UNFPA launched a youth networking zone called the &lsquo;coolibah&rsquo;, where young people will be able to speak with leaders in the field of HIV and AIDS. (Source: UNFPA News)
Discriminatory Capacity Between HIV-1 and HIV-2 of the New Rapid Confirmation Assay Geenius.
Authors: Herssens N, Beelaert G, Fransen K Abstract The currently used HIV confirmatory assays, Western blot and line immunoassay, are costly, complex and time-consuming. There is a need for cheaper, simpler and faster assays for use in high- and low-resource settings. Furthermore, it is necessary to differentiate between HIV-1 and HIV-2 infection due to differences in disease progression, monitoring and treatment options. Because the new Geenius HIV 1/2 Confirmatory Assay (Bio-Rad) has a European Community (CE) label, this study focused on its differentiation capacity using serum/plasma specimens from established HIV-1, HIV-2 and HIV untypable infections from the AIDS Reference Laboratory (ARL) of the Institute of Tropical Medicine (ITM) in Belgium. The results were compared with ...<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
This won't be the AIDS-free generation
He was just 18 years old when he got the news. It was the summer before his senior year in high school. Bryan Seth Johnson was diagnosed with the human immunodeficiency virus, better known as HIV. (Source: WDSU.com - Health)
Breaking Open Public Places: UNFPA Launches Coolibah - 21 July 2014
MELBOURNE, Australia &ndash; At the International AIDS Conference 2014 today, UNFPA, the United Nations Population Fund, launched a youth networking zone called the coolibah, where, throughout the week, it will host a range of activities for and with young people, including a series of luncheons with leaders in the field of HIV and AIDS. (Source: UNFPA News)
UNFPA engages young people in the fight against HIV - 21 July 2014
MELBOURNE, Australia &ndash; Every hour, about 80 young people are newly infected with HIV, according to the recently released Gap Report by UNAIDS. The participation and leadership of young people will therefore be critical in bringing the global HIV epidemic to an end. Today, at the 20th International AIDS Conference, UNFPA launched a youth networking zone called the &lsquo;coolibah&rsquo;, where young people will be able to speak with leaders in the field of HIV and AIDS. (Source: UNFPA News)
Mesenteric masses: Approach to differential diagnosis at MRI with histopathologic correlation
Magnetic resonance imaging (MRI) is an outstanding tool for the identification and characterization of mesenteric masses. Mesenteric masses may be solid or cystic. Most solid mesenteric masses are neoplastic, with sclerosing mesenteritis a notable exception. Entirely cystic mesenteric masses are typically benign. The excellent soft?tissue contrast afforded by MRI aids in narrowing the differential diagnosis of mesenteric masses. Accurately characterizing both solid and cystic mesenteric masses is important, as management ranges from active surveillance to medical management to surgical resection, depending on the tissue composition of the mass. An MRI?based approach to the differential diagnosis of mesenteric masses is presented.J. Magn. Reson. Imaging 2014. © 2014 Wiley Periodicals, ...
Oral Hepatitis C Drugs Helping Patients Coinfected With HIVOral Hepatitis C Drugs Helping Patients Coinfected With HIV
Results from TURQUOISE-1 and PHOTON-2 show that interferon-free regimens are achieving impressive response rates with few adverse events in patients coinfected with hep C and HIV. Medscape Medical News (Source: Medscape Gastroenterology Headlines)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Nigeria: Nigeria Doctors' Strike Threatens HIV/Aids Care
[VOA]Nearly a month into a nationwide doctor's strike, HIV/AIDS patients in some parts of northern Nigeria say health care is rapidly declining, and they have become largely dependent upon foreign aid organizations. Doctors say the strike is the only way they know to rescue Nigeria's flailing healthcare system, but nurses accuse strikers of abandoning public care in favor of more lucrative private practices. (Source: AllAfrica News: HIV-Aids and STDs)
Africa: Aids Conference Mourns the Dead, Debates Setbacks
[IPS]Melbourne -The 20th International AIDS Conference concluded today as the first in its history that remembered not just the 39 million people worldwide who have died of AIDS but also those who lost their lives in the crashed MH17 flight carrying six of its delegates, one of whom was the past president of the International AIDS Society (IAS). (Source: AllAfrica News: HIV-Aids and STDs)
[World Report] MH17 tragedy: HIV community mourns loss of colleagues
Organisers of this year's International AIDS Conference dedicated the meeting to the delegates who were killed on ill-fated flight MH17. Udani Samarasekera reports. (Source: LANCET)
Humanized PA14 (a monoclonal CCR5 antibody) for treatment of people with HIV infection.
CONCLUSIONS: Limited evidence from three small trials suggests that PRO 140 might demonstrate potent, short-term, dose-dependent, highly significant antiviral activity. However, as the evidence is insufficient, recommendations cannot yet be made. Larger, longer-term, double-blind RCTs are required to provide conclusive evidence. PMID: 25063928 [PubMed - as supplied by publisher] (Source: Cochrane Database of Systematic Reviews)
Considerations for Implementing Oral Pre-exposure Prophylaxis: A Literature Review
Oral pre-exposure prophylaxis (PrEP) is in its infancy as an approved biomedical intervention; therefore, research is needed to understand the issues surrounding its implementation. The purpose of this literature review is to report the empirical research about PrEP to identify the salient issues surrounding its implementation. PubMed, Medline, and CINAHL databases were searched yielding 45 articles meeting inclusion criteria for the review. Overall, we found patient awareness of PrEP varied and its use was low. (Source: Journal of the Association of Nurses in AIDS Care)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Breaking Open Public Places: UNFPA Launches Coolibah - 21 July 2014
MELBOURNE, Australia &ndash; At the International AIDS Conference 2014 today, UNFPA, the United Nations Population Fund, launched a youth networking zone called the coolibah, where, throughout the week, it will host a range of activities for and with young people, including a series of luncheons with leaders in the field of HIV and AIDS. (Source: UNFPA News)
UNFPA engages young people in the fight against HIV - 21 July 2014
MELBOURNE, Australia &ndash; Every hour, about 80 young people are newly infected with HIV, according to the recently released Gap Report by UNAIDS. The participation and leadership of young people will therefore be critical in bringing the global HIV epidemic to an end. Today, at the 20th International AIDS Conference, UNFPA launched a youth networking zone called the &lsquo;coolibah&rsquo;, where young people will be able to speak with leaders in the field of HIV and AIDS. (Source: UNFPA News)
Suicidal ideation among attendees of a West African HIV clinic - Ogundipe OA, Olagunju AT, Adeyemi JD.
This study was set to determine the prevalence of suicidal ideation and the associated risk factors among PLWHA.... (Source: SafetyLit: All (Unduplicated))
Risk factors associated with mental health issues in adolescents: a integrative review
Conclusion: The integrative review allowed to point important questions to be addressed in preventive actions by the health professional, including the nurse, to create a space that works with risk conditioning factors in adolescents for mental health aggravation.?Identificar los factores de riesgo asociados a los problemas de salud mental en adolescentes. Método: Se realizó una revisión integradora de artículos publicados entre los años 2007 y 2013 en cuatro bases de datos. Para la búsqueda de artículos, se utilizaron los descriptores: Salud Mental y Adolescencia, conforme a las bases DeCS/MeSH. Resultados: Se encontraron publicaciones en diferentes revistas, en distintos campos de conocimiento, siendo más frecuentes las investigaciones cuantitativas. Los problemas en salud ment...
Errata
Conclusion: The integrative review allowed to point important questions to be addressed in preventive actions by the health professional, including the nurse, to create a space that works with risk conditioning factors in adolescents for mental health aggravation.?Identificar los factores de riesgo asociados a los problemas de salud mental en adolescentes. Método: Se realizó una revisión integradora de artículos publicados entre los años 2007 y 2013 en cuatro bases de datos. Para la búsqueda de artículos, se utilizaron los descriptores: Salud Mental y Adolescencia, conforme a las bases DeCS/MeSH. Resultados: Se encontraron publicaciones en diferentes revistas, en distintos campos de conocimiento, siendo más frecuentes las investigaciones cuantitativas. Los problemas en salud ment...<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
This Week: AIDS Progress, Vegan Diet
(MedPage Today) -- Delegates to the IAC step up the pace, a top doctor's decision to go vegan, and disappointing results for robotic surgery topped this week's news at MedPage Today. (Source: MedPage Today Pediatrics)
Staying Sane as Medicine Goes CrazyStaying Sane as Medicine Goes Crazy
Technological advances, greater demands from patients and insurers, and a host of other stressors are pushing doctors to the brink. Despairing as it may sound, there are ways to regain control. Medscape Business of Medicine (Source: Medscape Hiv-Aids Headlines)
HIV Cure Still Years Away (CME/CE)
(MedPage Today) -- MELBOURNE, Australia -- The word "cure" is back in the HIV/AIDS vocabulary but the research is just out of the starting gate. (Source: MedPage Today Infectious Disease)
Controversy over ban on gay men donating blood
A lot has changed since the U.S. banned gay men from donating blood at the height of the AIDS scare in the 1980s; why is the policy still in place? (Source: Health News: CBSNews.com)
This won't be the AIDS-free generation
In the United States, 26% of all new HIV infections are among young people ages 13 to 24. Yet only 1 in 5 high school students is tested for HIV. (Source: CNN.com - Health)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
More Positive Stories Needed: HIV in Countries with Low ARV Therapy Coverage
  By Cecilia Ferreyra, MSF HIV & TB Technical Advisor More than 24 million people living with HIV; 9 million people on antiretroviral treatment (ART); 1.5 million new infections; 1.1 million deaths from AIDS-related causes. These are some of the data just released by UNAIDS on HIV/AIDS in sub-Saharan Africa in 2013, by far the area of ??the world hardest-hit by the virus. But, in this broad area covering nearly the entire continent, we see very different realities. (Source: MSF News)
Kenya: We Need a New Strategy to Fight HIV in Nyanza
[The Star]The Kenya HIV Prevention Revolution Road Map gives the glaring disparities in the number of HIV infections in all the 47 counties. Nairobi tops the list with close to 1.8 million HIV-positive people followed by all the counties in Nyanza except Nyamira. (Source: AllAfrica News: HIV-Aids and STDs)
Kenya: Group's Pledge to Fight HIV
[The Star]AN International HIV campaign programme has pledged to partner with the Homa Bay county government to reduce the spread of the disease. (Source: AllAfrica News: HIV-Aids and STDs)
Kenya: Young Men Report Having Several Sex Partners
[The Star]Young men between 15 and 24 years are sexually active and have multiple partners. A HIV report by the health ministry also reveals that a majority of women start having sex when they are 17 years. The report recommends behavioral change and condom use promotion. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Africa: HIV/Aids - More Positive Stories Needed
[MSF]As HIV & TB Technical Advisor for Médecins Sans Frontières (MSF), I have just returned from South Sudan, where I visited our project in Yambio, in Western Equatorial state. MSF supports the national HIV/AIDS programme there, with a special focus on pregnant women and children under five years of age. In general, the situation in South Sudan is the reality of many countries in West and Central Africa, where assistance to HIV-positive people is ineffective or nonexistent; and where conflict (Source: AllAfrica News: HIV-Aids and STDs)
Lift U.S. Ban on Blood Donations by Gay Men, Experts Say
American Red Cross, other groups also urge easing restrictions due to better blood screening (Source: Fertility News - Doctors Lounge)
Kenya: More Funding Needed for TB-HIV Co-Infection
[Key Correspondents]HIV and tuberculosis advocates say failure by donors and governments to invest more in these diseases may thwart efforts to end both epidemics resulting in thousands of preventable deaths. (Source: AllAfrica News: HIV-Aids and STDs)
Africa: Young People Must Play Leading Role in HIV Advocacy
[Key Correspondents]Delegates at the AIDS 2014 conference (20-25 July) are recognising that young people are the future and it is vital to empower them to take a leading role in the response to HIV. (Source: AllAfrica News: HIV-Aids and STDs)
Africa: Post 2015 Development Agenda and HIV - the Epidemic's Way Forward
[Key Correspondents]The end of AIDS has to be at the centre of the post-2015 development agenda to ensure the holistic, socio-economic development of communities around the world. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Africa: Young People Speak Out Against Stigma of Youth Condom Use
[Key Correspondents]Young people around the world are not receiving clear messages or support to use condoms to prevent HIV infection, according to delegates at the AIDS 2014 conference in Melbourne, Australia (20-25 July). (Source: AllAfrica News: Health and Medicine)
Africa: HIV Eradication Remains Challenging Milestone for Scientists
[Key Correspondents]"How come we have been able to fit everything that life needs into one mobile phone device we can keep in our pockets, but cannot find the cure for HIV?" This was a question a young man asked Dr Francoise Barre-Sinnousi, the International AIDS Society chief executive, in a discussion at the AIDS 2014 conference in Melbourne, Australia. (Source: AllAfrica News: Health and Medicine)
Africa: At Aids Conference, Prevention Pill Stirs Excitement
[VOA]Participants in this year's International AIDS Conference welcomed progress on a new pill that may prevent transmission of the deadly HIV virus - one of the advances that have provoked celebrations as well as debates. (Source: AllAfrica News: Health and Medicine)
Number of new HIV infection has decreased by 57%: Harsh Vardhan
Govt's objective was to reduce new infections further by 50% and provide comprehensive care and support to all persons living with HIV and AIDS. (Source: The Economic Times)
Breaking Open Public Places: UNFPA Launches Coolibah - 21 July 2014
MELBOURNE, Australia &ndash; At the International AIDS Conference 2014 today, UNFPA, the United Nations Population Fund, launched a youth networking zone called the coolibah, where, throughout the week, it will host a range of activities for and with young people, including a series of luncheons with leaders in the field of HIV and AIDS. (Source: UNFPA News)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
UNFPA engages young people in the fight against HIV - 21 July 2014
MELBOURNE, Australia &ndash; Every hour, about 80 young people are newly infected with HIV, according to the recently released Gap Report by UNAIDS. The participation and leadership of young people will therefore be critical in bringing the global HIV epidemic to an end. Today, at the 20th International AIDS Conference, UNFPA launched a youth networking zone called the &lsquo;coolibah&rsquo;, where young people will be able to speak with leaders in the field of HIV and AIDS. (Source: UNFPA News)
Africa: Police Must Play Role in Preventing HIV Among Criminalised Groups
[Key Correspondents]Delegates at the 20th International AIDS conference are tackling the issue of law enforcement policies and practices that often undermine the efforts of public health officials to reduce HIV transmission. (Source: AllAfrica News: HIV-Aids and STDs)
Kenya: HIV Related Complications Killed 58 Thousand Kenyans Last Year
[The Star]More than 58 thousand people died due to HIV related complications last year. A report by health ministry shows that the number of deaths of women were at 27,000, men at about 21,000 and children at 10,000. (Source: AllAfrica News: HIV-Aids and STDs)
Diagnostic role of ultrasound and elastosonography in nodular goiter.
Authors: Rago T, Vitti P Abstract Among several ultrasound patterns, thyroid nodule hypoechogenicity, spot microcalcifications, and an absent halo sign are used for predicting increased risk of thyroid malignancy. The predictive value of ultrasound, however, increases at the expense of its sensitivity, and malignancy is predicted with high specificity only when multiple ultrasound features are simultaneously present. Ultrasound features are important in determining the strength of the indication for carrying out fine needle aspiration. To this end, a system for standardization of ultrasound features (Thyroid Imaging Reporting and Data System) aids in establishing risk of malignancy. Ultrasound elastosonography is a technique that assesses hardness as an indicator of malignancy risk...
New licensing agreement could improve treatment options for children living with HIV
(Elizabeth Glaser Pediatric AIDS Foundation) The Elizabeth Glaser Pediatric AIDS Foundation applauds the new licensing agreement between the Medicines Patent Pool and Gilead Sciences, Inc. to improve access to tenofovir alafenamide fumarate, a promising new HIV medication. The agreement was announced during the 20th International AIDS Conference in Melbourne, Australia. While tenofovir alafenamide fumarate is still in Phase III clinical trials, early data suggests it could be a key ingredient in the next generation of first-line fixed-dose treatment options for children living with HIV. (Source: EurekAlert! - Infectious and Emerging Diseases)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Commissioning of hearing aids: response to Hearing Link?s campaign
The campaign, organised by Hearing Link, was called ?Stop the cuts to hearing aid services?. (Source: NHS Networks)
Maternal and health care workers' perceptions of the effects of exclusive breastfeeding by HIV positive mothers on maternal and infant health in Blantyre, Malawi
Conclusion: While most participants considered exclusive breastfeeding as an important component of the wellbeing of their infants' health, they did not share the worldwide acknowledged benefits of exclusive breastfeeding in the prevention of mother-to-child transmission (PMTCT) of HIV. These results suggest a need for more breastfeeding education for all mothers, communities and nurse-midwives involved in breastfeeding counseling in the context of HIV infection. Maternal wellbeing promotion activities such as nutrition supplementation need to be included in all PMTCT of HIV programs. (Source: BMC Pregnancy and Childbirth - Latest articles)
Progress toward prevention of transfusion-transmitted hepatitis B and hepatitis C infection - sub-saharan Africa, 2000-2011.
This report summarizes HBV- and HCV-related surveillance data reported by the blood transfusion services of WHO member states to WHO's Global Database on Blood Safety (GDBS) (4). It also evaluates the performance of blood safety programs in screening for HBV and HCV in 38 sub-Saharan Africa countries.* Selected GDBS indicators were compared for the years 2000 and 2004 (referred to as the 2000/2004 period) and 2010 and 2011 (referred to as the 2010/2011 period). From 2000/2004 to 2010/2011, the median of the annual number of units donated per country increased, the number of countries screening at least 95% of blood donations for HBV and HCV increased, and the median of the national prevalence of HBV and HCV marker-reactive blood donations decreased. These findings suggest that during the p...
Cancer Treatment Disparities in HIV-Infected Individuals in the United States [AIDS-Related Cancer]
Conclusion HIV-infected individuals are less likely to receive treatment for some cancers than uninfected people, which may affect survival rates. (Source: Journal of Clinical Oncology)
Glucose-6-phosphate dehydrogenase plays a critical role in hypoxia-induced CD133+ progenitor cells self-renewal...
Authors: Chettimada S, Joshi SR, Al Zoubi A, Gebb SA, McMurtry IF, Gupte RS, Gupte SA Abstract Although hypoxia is detrimental to most cell types, it aids survival of progenitor cells and is associated with diseases like cancer and pulmonary hypertension in humans. Here we demonstrate that the proliferation and growth of human CD133(+) progenitor cells, which contribute to tumorigenesis and the development of pulmonary hypertension, are increased when cultured under hypoxic conditions. Furthermore, glucose-6-phosphate dehydrogenase (G6PD) activity was increased 3-fold in hypoxic CD133(+) cells. The increased G6PD activity was required for CD133(+) cell proliferation, and their growth was arrested by G6PD inhibition or knockdown. G6PD activity upregulated expression of HIF1?, cycli...<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Maternal and health care workers¿ perceptions of the effects of exclusive breastfeeding by HIV positive mothers on maternal and infant health in Blantyre, Malawi
Conclusion: While most participants considered exclusive breastfeeding as an important component of the wellbeing of their infants? health, they did not share the worldwide acknowledged benefits of exclusive breastfeeding in the prevention of mother-to-child transmission (PMTCT) of HIV. These results suggest a need for more breastfeeding education for all mothers, communities and nurse-midwives involved in breastfeeding counseling in the context of HIV infection. Maternal wellbeing promotion activities such as nutrition supplementation need to be included in all PMTCT of HIV programs. (Source: BMC Pregnancy and Childbirth - Latest articles)
Developing Fly-Inspired, Piezoelectric Hearing Aids
Using a fly as inspiration, researchers at the University of Texas at Austin (UT) have created a miniature device that they say could lead to the development of hypersensitive hearing aids.Theresearchteam focused on theOrmia ochraceafly, which has a highly sophisticated hearing system. Contrary to other animals, insects generally cannot pinpoint sound sources because sound waves essentially hit both of their ears at the same time. TheOrmia ochraceafly&rsquo;s hearing system is different, as it contains tiny, teeter-totter-like mechanisms within the ear system that enable the fly to pinpoint sound sources within two degrees. (Source: Medical Design Online News)
Breaking Open Public Places: UNFPA Launches Coolibah - 21 July 2014
MELBOURNE, Australia &ndash; At the International AIDS Conference 2014 today, UNFPA, the United Nations Population Fund, launched a youth networking zone called the coolibah, where, throughout the week, it will host a range of activities for and with young people, including a series of luncheons with leaders in the field of HIV and AIDS. (Source: UNFPA News)
UNFPA engages young people in the fight against HIV - 21 July 2014
MELBOURNE, Australia &ndash; Every hour, about 80 young people are newly infected with HIV, according to the recently released Gap Report by UNAIDS. The participation and leadership of young people will therefore be critical in bringing the global HIV epidemic to an end. Today, at the 20th International AIDS Conference, UNFPA launched a youth networking zone called the &lsquo;coolibah&rsquo;, where young people will be able to speak with leaders in the field of HIV and AIDS. (Source: UNFPA News)
Cancer Drug First to Wake Dormant HIVCancer Drug First to Wake Dormant HIV
An HDAC inhibitor used to treat cancer drives enough concealed HIV out of hiding for the virus to be detected on standard testing, report researchers. Medscape Medical News (Source: Medscape Medical News Headlines)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Integrated Guidance for Developing Epidemiologic Profiles
This guidance has been developed by the Centers for Disease Control and Prevention (CDC) and the Health Resources and Services Administration (HRSA) to assist persons who compile and interpret HIV prevention and care data for state, territorial, or local HIV epidemiologic profiles. (Source: CDC HIV/AIDS Prevention)
Bacteria in Semen May Affect HIV Transmission, Levels: Study
As natural bacterial 'diversity' lessened, HIV viral load increased in infected men, researchers say (Source: Fertility News - Doctors Lounge)
Africa: Geldof Says Australia Aid Cuts Could Have Helped HIV Battle
[AlertNet]Melbourne -Irish campaigner and musician Bob Geldof said on Thursday that achieving the end to poverty was just as possible as achieving the end to AIDS. (Source: AllAfrica News: HIV-Aids and STDs)
Kenya: About Half of HIV Infections Occur in Unions
[The Star]Close to half of HIV infections occur among people who have sex within a union. A HIV report also reveals that key populations including sex workers, men having sex with men, prisoners and injecting drug users account for a third of the new infections. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Latest HIV 'cure' claims prompt calls for more caution
Bone marrow grafts have helped both patients stay all but virus-free for three years. But the disease has come back before in others, and a simpler treatment is needed (Source: New Scientist - HIV and AIDS)
Zimbabwe: HIV/Aids Have Robbed Zimbabwe of a Healthy Workforce - Minister Bimha
[The Herald]THE Minister of Industry and Commerce Mike Bimha has lamented the damage HIV and AIDS have had on the Zimbabwe workforce and said this devastation has reversed development and retarded the economic growth of the country. (Source: AllAfrica News: HIV-Aids and STDs)
Zimbabwe: Parirenyatwa Courts Indian Firm On ARVs
[The Herald]Health and Child Care Minister Dr David Parirenyatwa yesterday met with representatives of an Indian drug manufacturer, Myland, which has shown interest in partnering Zimbabwean pharmaceutical companies to produce anti-retroviral drugs locally.In an interview with The Herald on the sidelines of the 20th International Aids Conference here soon after the meeting, Dr Parirenyatwa said they were still courting the manufacturer and if the deal sailed through, production of the drugs locally would have massive b (Source: AllAfrica News: HIV-Aids and STDs)
Zimbabwe: Remember the Youths in HIV Fight
[The Herald]AT least 12 000 delegates from 200 countries are meeting this week in Melbourne, Australia, for the 20th International AIDS Conference. This comes at a time the United Nations has set a new target of 2030 to eliminate AIDS, TB and malaria as major global killers. Initially all Millennium Development Goals (MDGs) were supposed to be achieved by 2015. That has not been possible. (Source: AllAfrica News: HIV-Aids and STDs)
South Africa: DA Welcomes Additional R1 Billion for ARVs
[DA]The DA welcomes the announcement made yesterday by Health Minister, Dr Aaron Motsoaledi, that an additional 2 million HIV-positive South Africans, with a CD4 count of 500, will be placed on Anti-Retroviral (ARV) treatment over the next 3 years. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Cochlear protests Medicare exclusion of Baha hearing implant
Hearing devices maker Cochlear Limited warns that Medicare's proposed rule change could limit access to certain cochlear implants. A proposed change to Medicare's reimbursement of hearing aids could leave patients on their own when they need the a specific type of bone-anchored hearing aid implant, according to device maker Cochlear Ltd. (ASX:COH). Centers for Medicare and Medicaid Services (CMS), Cochlear Ltd.News Well, Hearing, Implants, Medicare, Reimbursementread more (Source: Mass Device)
Who needs college? Pre-baccalaureate workers a growing percentage of health care workforce
More than half of America's health care workforce has an associate's degree or less, according to a new report from the Brookings Metropolitan Policy Program. The report showed 43 percent of all health care workers fall into the pre-baccalaureate category in the 10 largest pre-baccalaureate occupations. Those 10 occupations include home health aids, registered nurses, personal care aides, practical and vocational nurses, medical and dental assistants, diagnostic and laboratory technologists and? (Source: bizjournals.com Health Care:Physician Practices headlines)
Africa: Communities Must Remain At the Forefront of HIV Response
[Key Correspondents]Governments and policymakers are failing to involve communities in HIV and TB programmes, turning instead to researchers and experts to make key decisions. This issue has triggered debate at the AIDS 2014 conference in Melbourne, Australia (20-25 July) as representatives of some African communities claim they are being locked out of the HIV response. (Source: AllAfrica News: HIV-Aids and STDs)
Africa: We Must Step Up the Pace to End Aids
[Key Correspondents]Malaysian Airlines Flight MH17 was sadly at the centre of discussions as the AIDS 2014 Conference commenced in Melbourne on 20 July. (Source: AllAfrica News: HIV-Aids and STDs)
Africa: Children With HIV Left Behind in the Race Towards Treatment for All
[Key Correspondents]Ahead of this week's 20th International AIDS Conference, experts have warned that children are being left behind in the goal to reach universal access to HIV treatment. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Rwanda: Fight HIV/Aids Stigma in Schools
[New Times]This week's lead story on how schools are dealing with the challenge of HIV-infected students, while encouraging, illustrates just how far we still have to go in the fight against the killer pandemic in our midst. (Source: AllAfrica News: HIV-Aids and STDs)
Africa: U.S Ambassador Calls for LGBT Rights
[VOA]The U.S. ambassador to Australia said it should not be a crime to be a member of the LGBT community. Ambassador John Berry told the 20th international AIDS Conference that the fight against the disease cannot be won by relegating segments of the population to the shadows. (Source: AllAfrica News: HIV-Aids and STDs)
Nigeria: 2.6 Million Living With HIV/Aids to Access Services
[Guardian]Abuja -THE International Federation of Red Cross and Red Crescent Societies (IFRC) has said the 2.6 million people living with HIV in Benue and Cross River States are to benefit from improved access to qualitative treatment. (Source: AllAfrica News: HIV-Aids and STDs)
Nigeria: Nigerians Seek Own HIV/Aids Drugs, Test Kits
[Independent]A cross section of Nigerians has said the country could make remarkable progress in most aspects if the burden of HIV and AIDS is This is in view of reports by the Joint United Nations Programme on HIV/AIDS (UNAIDS) that, Nigeria has the second largest HIV epidemic globally. (Source: AllAfrica News: HIV-Aids and STDs)
Breaking Open Public Places: UNFPA Launches Coolibah - 21 July 2014
MELBOURNE, Australia &ndash; At the International AIDS Conference 2014 today, UNFPA, the United Nations Population Fund, launched a youth networking zone called the coolibah, where, throughout the week, it will host a range of activities for and with young people, including a series of luncheons with leaders in the field of HIV and AIDS. (Source: UNFPA News)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
UNFPA engages young people in the fight against HIV - 21 July 2014
MELBOURNE, Australia &ndash; Every hour, about 80 young people are newly infected with HIV, according to the recently released Gap Report by UNAIDS. The participation and leadership of young people will therefore be critical in bringing the global HIV epidemic to an end. Today, at the 20th International AIDS Conference, UNFPA launched a youth networking zone called the &lsquo;coolibah&rsquo;, where young people will be able to speak with leaders in the field of HIV and AIDS. (Source: UNFPA News)
The prevalence of transmitted HIV drug resistance among MSM in Anhui province, China.
CONCLUSIONS: In Anhui, CRF01_AE strains contributed to most of the HIV infections among MSM, and the prevalence of TDR was relatively low in this population. Further studies should be performed to evaluate the trend of TDR among MSM in Anhui and to inform first-line antiretroviral treatment. PMID: 25035709 [PubMed] (Source: AIDS Research and Therapy)
Virologic outcomes of second-line antiretroviral therapy in Eastern European country of Georgia.
CONCLUSIONS: The study demonstrated favourable virological outcomes of the second-line ART in Georgia. Majority of patients, including IDUs, achieved sustained virological response over 36 month period. The findings highlight the need of improving adherence. PMID: 25035708 [PubMed] (Source: AIDS Research and Therapy)
Nigeria: New Drug Flushes Out HIV... but
[Independent]Scientists say they have made an exciting step towards curing HIV by forcing the virus out of its reservoirs. But they have also warned that when the drug treatment stops, the virus can leap out of the reservoir and renew its assault. (Source: AllAfrica News: HIV-Aids and STDs)
Short Communication: HIV-1 Gag Genetic Variation in a Single Acutely Infected Participant Defined by High-Resolution Deep Sequencing
AIDS Research and Human Retroviruses , Vol. 0, No. 0. (Source: AIDS Research and Human Retroviruses)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Victoria A. Harden, AIDS at 30: A History
(Source: Social History of Medicine)
Rifamycin Analog Production by Combinatorial Biosynthesis [Gene Regulation]
Rifamycin B, a product of Amycolatopsis mediterranei S699, is the precursor of clinically used antibiotics that are effective against tuberculosis, leprosy, and AIDS-related mycobacterial infections. However, prolonged usage of these antibiotics has resulted in the emergence of rifamycin-resistant strains of Mycobacterium tuberculosis. As part of our effort to generate better analogs of rifamycin, we substituted the acyltransferase domain of module 6 of rifamycin polyketide synthase with that of module 2 of rapamycin polyketide synthase. The resulting mutants (rifAT6::rapAT2) of A. mediterranei S699 produced new rifamycin analogs, 24-desmethylrifamycin B and 24-desmethylrifamycin SV, which contained modification in the polyketide backbone. 24-Desmethylrifamycin B was then converted to 24-d...
Raltegravir Not Better Than NRTIs for Refractory HIVRaltegravir Not Better Than NRTIs for Refractory HIV
Raltegravir showed no benefits over nucleoside reverse-transcriptase inhibitors when used in combination with a protease inhibitor as second-line HIV therapy. Medscape Medical News (Source: Medscape Medical News Headlines)
'Kick' Study Excites AIDS Meeting
(MedPage Today) -- MELBOURNE, Australia -- A trial with only six patients and no dramatic clinical outcomes rarely creates much of a buzz, but delegates to the International AIDS Conference here are talking up just such a study. (Source: MedPage Today Infectious Disease)
HIV Meds May Also Help Control Hepatitis C, Study Finds
For people infected with both viruses, early treatment is critical, researchers report (Source: Fertility News - Doctors Lounge)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Clinton to AIDS Conference: Step It Up
(MedPage Today) -- MELBOURNE, Australia -- The destruction of a jet with six AIDS researchers and activists aboard is a "stark reflection" of the negative side of an interdependent world, former President Bill Clinton said here. (Source: MedPage Today Public Health)
The Use of Positive Psychology in Addiction Treatment
?Positive Psychology is the scientific study of the strengths and virtues that enable individuals and communities to thrive." Here is how positive psychology aids addiction treatment.read more (Source: Psychology Today Addiction Center)
Malawi: None Reporting of HIV Activities Affecting Progress in HIV Fight
[Malawi News Agency]Salima -The HIV review meeting for Salima district council has exposed under reporting of HIV activities by stake holders, as only 30 percent of organizations in this sector reported their 2013-2014 activities. (Source: AllAfrica News: HIV-Aids and STDs)
Kenya: Kenyans Having Sex Without Protection
[The Star]Kenyans are continuously having sex without a condom despite not knowing the HIV status of their partners. A HIV report by the health ministry shows that only 5% of women between 25-64 years and 11% of men in the same age group consistently use a condom with partners of unknown status. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
South Africa: SA's Big HIV/Aids 2030 Plan
[SAnews.gov.za]Health Minister Dr Aaron Motsoaledi says government has big plans to turn the tide on HIV/Aids by 2030, in line with the target set by delegates at the International Aids Conference in Australia. (Source: AllAfrica News: Health and Medicine)
Africa: U.S. Awards Another $500 Million to Achieve AIDS-Free Generation
[State Department]Melbourne, Australia -More than $500 million in additional U.S. funding will support global HIV and AIDS response efforts with 19 partners. (Source: AllAfrica News: Health and Medicine)
Africa: UNDP Administrator Sees Stronger Role for Lawmakers in Eradicating AIDS
[UNDP]Melbourne, Australia -Tackling HIV requires courageous and committed policy-makers and law-makers said the UN's development chief at the 20th International AIDS Conference. (Source: AllAfrica News: HIV-Aids and STDs)
Kenya: 65 Percent of New HIV Infections in Only Nine Counties
[The Star]65% of new HIV infections occur in only nine of the 47 counties. The Kenya HIV prevention revolution road map shows that new infection rates are highest in Homa Bay, Kisumu, Siaya, Migori and Kisii counties respectively. (Source: AllAfrica News: HIV-Aids and STDs)
Zimbabwe: HIV Disclosure - Changing Ourselves, Changing Others
[New Zimbabwe]When will policy makers, politicians and academics start to think upstream, in order to change their own and their employees' attitudes towards HIV before seeking to change the attitudes of others? (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Namibia: Group Fights HIV in Truck Drivers
[Namibian]ABOUT 148 truck drivers out of 1 104 who tested for HIV between 2012 and June 2014 were positive, according to statistics given by the Walvis Bay Corridor Group (WBCG). (Source: AllAfrica News: HIV-Aids and STDs)
Africa: Sex Workers Seek HIV Prevention
[VOA]A new series in the medical journal The Lancet says achieving an AIDS-free generation will not be possible unless the human rights of sex workers are recognized. Researchers say sex workers face violence and discrimination and are not able to access the care, treatment and prevention measures they need. (Source: AllAfrica News: Health and Medicine)
South Africa: Aids Still Extracting a Deadly Price, but SA Is Making Progress
[Health-e]South Africa has more Aids-related deaths than any country in the world, but deaths of young children have decreased more than ten-fold in the past decade and tuberculosis (TB) deaths have decreased by 6 percent. (Source: AllAfrica News: HIV-Aids and STDs)
Uganda: At Lake Katwe Condoms Protect Men From Salt
[Observer]Around the salty Lake Katwe in western Uganda, condoms have taken on a unique usage, rather than preventing the spread of sexually-transmitted diseases such as HIV/Aids. (Source: AllAfrica News: HIV-Aids and STDs)
Zimbabwe: Sex-for-Food Scheme Expose Children to STIs
[CAJ News]Masvingo -HUNDREDS of people, among them monitors as young as 14, have contracted sexually transmitted diseases (STDs) since the beginning of the year as the situation at the Chingwizi transit camp turn dire by the day. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
On the Evolution of AIDS/HIV Treatment: An Optimal Control Approach.
Authors: Biswas HA Abstract After more than 30 years of continuous research as well as unselfish efforts, tremendous and exciting developments have been achieved towards the evolution of HIV treatments both in the directions of antiretroviral therapy and effective vaccine for HIV positive patients. Recent research shows that triple-drug antiretroviral therapy can 'functionally cure' [1, 2] the HIV positive patients, which is a milestone in the therapeutic treatments of AIDS. Despite the significant progress on the evolution of AIDS/HIV treatments, it is still a curse for the humanity and until today the world's most serious epidemic as well as leading infectious killer disease. However, Millennium Development Goals (MDGs) Getting to Zero shows a hope to build up a new world without...
Expression Profiles of Endogenous Retroviral Envelopes in Macaca Mulatta (Rhesus Monkey)
AIDS Research and Human Retroviruses , Vol. 0, No. 0. (Source: AIDS Research and Human Retroviruses)
Latest HIV purge claims prompt calls for more caution
Bone marrow grafts have helped both patients stay all but virus-free for three years. But the disease has come back before in others, and a simpler treatment is needed (Source: New Scientist - HIV and AIDS)
Problem-Focused Coping: Skipped-Generation Caregivers Affected by HIV/AIDS in Vietnam
In this article, we examine skipped-generation caregivers who foster their grandchildren orphaned by HIV/AIDS in Vietnam. We investigated the challenges facing this population and the ways in which grandparents handled their trials on behalf of their families. Specifically, how did caregivers make sense of their roles, and how did these meanings inform their coping strategies? We conducted in-depth qualitative interviews with 21 older caregivers and 7 key informants and selected 5 caregivers from the sample to complete participant observations. The participants understood coping as problem-focused coping; for example, by considering a set of caregiving-related activities that included providing childcare, making money, borrowing money, cooking, and doing other daily chores. The voices of o...
The Organelle-focused Proteomes and Interactomes in Rice.
Authors: Liu L, Jiang L, Chen M Abstract Protein subcellular localization has been a long-standing key problem in investigating proteins' function, which provides important clues for revealing their functions and aids in understanding their interactions with other biomolecules at the cellular level. Here, we systematically defined the organelle-focused proteome and interactome in Oryza sativa. A total of 83.42% of the whole rice proteome obtained their subcellular localizations based on manual annotation, manual adjustment and predictors' cross validation. The final organelle-focused interactome were located in nine organelles. Furthermore, we discussed the cross talk bias between different organelles and the function organization accounting for nine organelles. Motif analysis illu...<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Celastrol ameliorates HIV-1 Tat-induced inflammatory responses via NF-kappaB and AP-1 inhibition and heme oxygenase-1 induction in astrocytes.
In this study, we investigated the modulatory effects of celastrol on HIV-1 Tat-induced inflammatory responses and the molecular mechanisms underlying its action in astrocytes. Pre-treatment of CRT-MG human astroglioma cells with celastrol significantly inhibited HIV-1 Tat-induced expression of ICAM-1/VCAM-1 and subsequent monocyte adhesiveness in CRT-MG cells. In addition, celastrol suppressed HIV-1 Tat-induced expression of pro-inflammatory chemokines, such as CXCL10, IL-8, and MCP-1. Celastrol decreased HIV-1 Tat-induced activation of JNK MAPK, AP-1, and NF-?B. Furthermore, celastrol induced mRNA and protein expression of HO-1 as well as Nrf2 activation. Blockage of HO-1 expression using siRNA reversed the inhibitory effect of celastrol on HIV-1 Tat-induced inflammatory responses. Thes...
eSNaPD: A Versatile, Web-Based Bioinformatics Platform for Surveying and Mining Natural Product Biosynthetic Diversity from Metagenomes.
Authors: Reddy BV, Milshteyn A, Charlop-Powers Z, Brady SF Abstract Environmental Surveyor of Natural Product Diversity (eSNaPD) is a web-based bioinformatics and data aggregation platform that aids in the discovery of gene clusters encoding both novel natural products and new congeners of medicinally relevant natural products using (meta)genomic sequence data. Using PCR-generated sequence tags, the eSNaPD data-analysis pipeline profiles biosynthetic diversity hidden within (meta)genomes by comparing sequence tags to a reference data set of characterized gene clusters. Sample mapping, molecule discovery, library mapping, and new clade visualization modules facilitate the interrogation of large (meta)genomic sequence data sets for diverse downstream analyses, including, but not limi...
Aided cortical response, speech intelligibility, consonant perception and functional performance of young children using conventional amplification or nonlinear frequency compression
The aim of this study was to compare conventional processing with nonlinear frequency compression (NLFC) in hearing aids for young children with bilateral hearing loss. (Source: International Journal of Pediatric Otorhinolaryngology)
Spatial Relationships Between Gay Stigma, Poverty, and HIV Infection Among Black and White Men Who Have Sex with Men in Atlanta
AIDS Research and Human Retroviruses , Vol. 0, No. 0. (Source: AIDS Research and Human Retroviruses)
Sexual behavior among Brazilian adolescents, National Adolescent School-based Health Survey (PeNSE 2012)
CONCLUSION: The information on preventing pregnancy and STD/AIDS need to be disseminated before the 9th grade. Social inequalities negatively affect risky sexual behavior. Substance use is strongly associated with unprotected sex. Information on the prevention of pregnancy and STD/AIDS need to be disseminated early. OBJETIVO: Este estudo descreve o comportamento sexual entre estudantes que participaram da Pesquisa Nacional sobre a Saúde do Escolar (PeNSE) 2012 e investiga se as desigualdades sociais, o uso de substâncias psicoativas e a presença de informações sobre a saúde sexual e reprodutiva na escola estão associados a diferenças nesse comportamento. METODOLOGIA: A variável resposta foi o comportamento sexual descrito em três categorias (nunca teve relação sexual, teve rel...<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Sexual behavior of school-aged adolescents in the city of Goiânia, Goiás
CONCLUSION: Results showed a need for health education measures involving education and health professionals, as well as parents, to reduce the discrepancies found regarding sex and type of school. OBJETIVO: Investigar as características do comportamento sexual de adolescentes escolares e verificar se há diferenças em relação ao sexo dos estudantes e ao tipo de escola. MÉTODOS: Estudo transversal utilizando dados da Pesquisa Nacional de Saúde do Escolar (PeNSE) 2009, realizada pelo Ministério da Saúde em parceria com o IBGE. A amostra foi composta por 3.099 escolares do 9° ano residentes em Goiânia (GO), com predomínio das idades de 13 a 15 anos, que responderam um questionário sobre fatores de risco e proteção à saúde. Na análise estatística, foi utilizado o teste de R...
Credibility Among Gay Men Gives Leverage to New York City?s New Chief of H.I.V. Prevention
Dr. Demetre Daskalakis will soon be in charge of one of the health department?s largest bureaus at a critical moment in the history of the virus that causes AIDS. (Source: NYT Health)
Breaking Open Public Places: UNFPA Launches Coolibah - 21 July 2014
MELBOURNE, Australia &ndash; At the International AIDS Conference 2014 today, UNFPA, the United Nations Population Fund, launched a youth networking zone called the coolibah, where, throughout the week, it will host a range of activities for and with young people, including a series of luncheons with leaders in the field of HIV and AIDS. (Source: UNFPA News)
UNFPA engages young people in the fight against HIV - 21 July 2014
MELBOURNE, Australia &ndash; Every hour, about 80 young people are newly infected with HIV, according to the recently released Gap Report by UNAIDS. The participation and leadership of young people will therefore be critical in bringing the global HIV epidemic to an end. Today, at the 20th International AIDS Conference, UNFPA launched a youth networking zone called the &lsquo;coolibah&rsquo;, where young people will be able to speak with leaders in the field of HIV and AIDS. (Source: UNFPA News)
DHAP Annual Report
This document highlights programmatic activities of the CDC Division of HIV/AIDS Prevention in 2013. (Source: CDC HIV/AIDS Prevention)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
New HIV Guidelines Released by WHONew HIV Guidelines Released by WHO
The recommendations target marginalized groups reportedly responsible for much of the global HIV epidemic. Medscape Medical News (Source: Medscape Medical News Headlines)
Scientists cut HIV directly out of infected human genome using molecular tools
Scientists have taken an ?important step? towards a permanent cure for AIDS by using specially designed enzymes to physically cut the HIV virus out of an infected human genome. (Source: The Independent - Science)
Scientists cut HIV directly out of the human genome using molecular tools
Scientists have taken an ?important step? towards a permanent cure for AIDS by using specially designed enzymes to physically cut the HIV virus out of the human genome. (Source: The Independent - Science)
Africa: Helen Clark - Speech On "Beyond the MDGs: HIV and the Post-2015 Agenda" At the 20th International Aids Conference
[UNDP]"Beyond the MDGs: HIV and the Post -"2015 Agenda" (Source: AllAfrica News: Pregnancy and Childbirth)
Africa: HIV/Aids Resource Adds Data From More Than 100 Countries
[State Department]Washington -The U.S. Census Bureau on July 21 released its annually updated interactive global resource on HIV prevalence, AIDS cases and AIDS deaths. The database is the most comprehensive resource of its kind in the world, according to the U.S. Commerce Department, which includes the Census Bureau. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Africa: USAID Announces +$500 Million for New Efforts to Reach an Aids-Free Generation At Conference in Melbourne, Australia
[USAID]Melbourne -Major awards with 19 partners to support global HIV and AIDS response (Source: AllAfrica News: HIV-Aids and STDs)
HIV: Viral Rebound After Bone Marrow TransplantHIV: Viral Rebound After Bone Marrow Transplant
Case reports of 2 men with HIV who were in transient remission after bone marrow transplant showed that their viral loads rebounded after stopping ART. Medscape Medical News (Source: Medscape Medical News Headlines)
South Africa: Better, Shorter TB Treatment - Thanks to SA Scientists
[Health-e]South African scientists may be en route to developing shorter, better tuberculosis (TB) treatment, according to research released at the International AIDS Conference in Melbourne, Australia. (Source: AllAfrica News: Tuberculosis)
Africa: African Anti-Gay Laws Challenge Health Care
[VOA]African Anti -President Goodluck Jonathan of Nigeria and President Yoweri Museveni of Uganda are two African leaders who embrace legislation which targets the gay community. In Uganda, an anti-homosexuality law criminalizes same-sex relations, while in Nigeria, same sex couples that show affection in public risk ten years imprisonment. The laws in both countries are forcing communities vulnerable to HIV deeper into the shadows. (Source: AllAfrica News: HIV-Aids and STDs)
Nigeria: HIV/Aids Cure Suffers Setback With Demise of Joep Lange
[Leadership]Abuja -The United Nations Agency for HIV/AIDS (UNAIDS), has expressed deep sadness over the loss of life of the passengers and crew of flight MH17, which crashed over eastern Ukraine on Thursday, July 17, 2014, among them a staff of the World Health Organisation (WHO). (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Africa: Does Anybody Remember Aids?
[GroundUp]This week thousands of activists, scientists and government officials will troop to Melbourne, Australia, to participate in the 20th International AIDS Conference. (Source: AllAfrica News: HIV-Aids and STDs)
Breaking Open Public Places: UNFPA Launches Coolibah - 21 July 2014
MELBOURNE, Australia &ndash; At the International AIDS Conference 2014 today, UNFPA, the United Nations Population Fund, launched a youth networking zone called the coolibah, where, throughout the week, it will host a range of activities for and with young people, including a series of luncheons with leaders in the field of HIV and AIDS. (Source: UNFPA News)
UNFPA engages young people in the fight against HIV - 21 July 2014
MELBOURNE, Australia &ndash; Every hour, about 80 young people are newly infected with HIV, according to the recently released Gap Report by UNAIDS. The participation and leadership of young people will therefore be critical in bringing the global HIV epidemic to an end. Today, at the 20th International AIDS Conference, UNFPA launched a youth networking zone called the &lsquo;coolibah&rsquo;, where young people will be able to speak with leaders in the field of HIV and AIDS. (Source: UNFPA News)
Oral Pre-Exposure Prophylaxis (PrEP) for Prevention of HIV in Serodiscordant Heterosexual Couples in the United States: Opportunities and Challenges
AIDS Patient Care and STDs , Vol. 0, No. 0. (Source: AIDS Patient Care and STDs)
Exari Launches 'SmartDocs'; Aids ACLA Members in Complex Clause Creation, Negotiation
(Source: Medical News (via PRIMEZONE))<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
More bad news in fight against persistent HIV reservoirs
July has been a particularly trying month for HIV/AIDS researchers as they mourned the loss of colleagues killed in a militant attack and received new reports of the virus' remarkable tenacity. (Source: Los Angeles Times - Science)
Delegates mourn MH17 passengers
Authors: Katia Moskvitch & Edward Susman AIDS conference tries to draw inspiration from lost scientists. (Source: Nature)
Antiretroviral-Free HIV-1 Remission and Viral Rebound After Allogeneic Stem Cell Transplantation: Report of 2 Cases.
Conclusion: Allogeneic HSCT may lead to loss of detectable HIV-1 from blood and gut tissue and variable periods of antiretroviral-free HIV-1 remission, but viral rebound can occur despite a minimum 3-log10 reduction in reservoir size. Long-lived tissue reservoirs may have contributed to viral persistence. The definition of the nature and half-life of such reservoirs is essential to achieve durable antiretroviral-free HIV-1 remission. Primary Funding Source: Foundation for AIDS Research and National Institute of Allergy and Infectious Diseases. PMID: 25047577 [PubMed - as supplied by publisher] (Source: Annals of Internal Medicine)
Connecting the dots: Could microbial translocation explain commonly reported symptoms in HIV disease?
Microbial translocation within the context of HIV disease has been described as one of the contributing causes of inflammation and disease progression in HIV infection. HIV-associated symptoms have been related to inflammatory markers and sCD14, a surrogate marker for microbial translocation, suggesting a plausible link between microbial translocation and symptom burden in HIV disease. Similar pathophysiological responses and symptoms have been reported in inflammatory bowel disease (IBD). We provide a comprehensive review of microbial translocation, HIV-associated symptoms, and symptoms connected with inflammation. (Source: Journal of the Association of Nurses in AIDS Care)
Exploiting the anti-HIV 6-desfluoroquinolones to design multiple ligands.
Authors: Sancineto L, Iraci N, Barreca ML, Massari S, Manfroni G, Corazza G, Cecchetti V, Marcello A, Daelemans D, Pannecouque C, Tabarrini O Abstract It is getting clearer that many drugs effective in different therapeutic areas act on multiple rather than single targets. The application of polypharmacology concepts might have numerous advantages especially for disease such as HIV/AIDS, where the rapid emergence of resistance requires a complex combination of more than one drug. In this paper, we have designed three hybrid molecules combining WM5, a quinolone derivative we previously identified as HIV Tat-mediated transcription (TMT) inhibitor, with the tricyclic core of nevirapine and BILR 355BS (BILR) non-nucleoside reverse transcriptase inhibitors (NNRTIs) to investigate whethe...<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
AIDS Conference Organizers Honor Delegates Downed in PlaneAIDS Conference Organizers Honor Delegates Downed in Plane
AIDS 2014 opened with a moment of silence as participants paid tribute to at least 6 registered attendees who lost their lives on the Malaysia Airlines flight en route to the conference. Medscape Medical News (Source: Medscape Allergy Headlines)
Efficacy of an Evidence-Based ARV Adherence Intervention in China
AIDS Patient Care and STDs , Vol. 0, No. 0. (Source: AIDS Patient Care and STDs)
Scientists Snipped HIV Out of Human DNA
Molecular tool might lead to more definitive treatment, but current research didn't treat patients, just cells Source: HealthDay Related MedlinePlus Pages: Genes and Gene Therapy, HIV/AIDS (Source: MedlinePlus Health News)
Animal Experiments Shed Light on HIV's Ability to Hide
Viral 'reservoir' in body develops earlier than thought, thwarting attempts at cure, scientists saySource: HealthDay Related MedlinePlus Page: HIV/AIDS (Source: MedlinePlus Health News)
Updates from Team Nduruma
Mambo! VP3 here in the lovely village of Nduruma. We are rounding up our second week in the village and have enjoyed getting to know Nduruma and its inhabitants a little more everyday. Before we delve into the nitty gritty of our lives here, a brief introduction to the Nduruma SIC team is in order. &nbsp; Aaron: Aaron is from the University of Dodoma. He hates music and owns dirt-repelling white shoes. Poa! Keaton: Keaton is from the University of San Francisco. He is highly praised here in Nduruma. Everybody just loves him. Ben: Ben is from Stanford. He loves (LOVES) cats and has one dance move. Taylor: Taylor is from UCLA. She is well traveled and coming to Tanzania was NO big deal. She is open to trying all sorts of food. Hilal: Hilal is from the University of Dodoma. He doesn?t reall...<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Hello from Team Marurani!
We wake up to the alarms of our smart phones, or more likely, to the domestic noises that have undoubtedly started with a punctuality and intensity I could not imagine for such an hour of the day. Tea and coffee is on the table with sweet smelling, oily tasting simple donuts, called mandazi. We bow our heads as our house father, or baba, mutters thanks in Swahili to God. We dress ourselves as the locals do, long traditional skirts and blouses for women, t-shirts, jeans, and sneakers for men. We try to fit into this foreign world. We lives in the same kind of houses, use the same blankets for showers, and walk the same dirty roads. We try, at least, to live the same kind of life as those who we are teaching. We dot it to create solidarity and empathy. By living in the field away form famili...
HIV diagnosis rate drops significantly
It's a sign that the AIDS epidemic may be slowing, but some exceptions raise concerns (Source: Health News: CBSNews.com)
Breaking Open Public Places: UNFPA Launches Coolibah - 21 July 2014
MELBOURNE, Australia&mdash; At the International AIDS Conference 2014 today, UNFPA launched a youth networking zone called the coolibah, where, throughout the week, it will host a range of activities for and with young people, including a series of luncheons with leaders in the field of HIV and AIDS. (Source: UNFPA News)
Kenya: Controlling HIV-Aids By 2030 Is Possible - UNAIDS
[The Star]HIV/Aids, one of Africa's biggest killer, may be no more or will be under control in the next 20 or so years if medication is availed to everyone infected and awareness spread, statistics show. (Source: AllAfrica News: HIV-Aids and STDs)
Africa: Controlling HIV-Aids By 2030 Is Possible - UNAIDS
[The Star]HIV/Aids, one of Africa's biggest killer, may be no more or will be under control in the next 20 or so years if medication is availed to everyone infected and awareness spread, statistics show. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
'Bad' laws hurt sex workers, gays from Uganda to Nepal, AIDS meeting told
MELBOURNE (Thomson Reuters Foundation) - After Uganda passed a law that punished gay sex with long prison sentences, Daisy Nakato got a visit from the police. (Source: Reuters: Health)
Kenya: HIV Message Needs to Target Young People
[The Star]HIV Message Needs To Target Young People. Photo/Monica Mwangi (Source: AllAfrica News: HIV-Aids and STDs)
Africa: Circumcision Does Not Promote Risky Behaviour
[VOA]A new study that could boost HIV prevention efforts says African men do not engage in riskier sexual behaviour after being circumcised. Research has shown that circumcision can greatly reduce men's risk of being infected with the AIDS virus. The study's been released as the 20th International AIDS Conference opens in Melbourne, Australia. (Source: AllAfrica News: Health and Medicine)
Retention in HIV Care in Year 1: Who's In and Who's Out?Retention in HIV Care in Year 1: Who's In and Who's Out?
Which patients are less likely to be retained in HIV care? Journal of the International Association of Providers of AIDS Care (Source: Medscape Today Headlines)
Africa: Helen Clark - Keynote Address to the Meeting of the Parliamentarians At the 20th International Aids Conference
[UNDP]Helen Clark, UNDP Administrator (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Nigeria: Nigeria Records 35 Percent Drop in HIV Infections-Report
[Daily Trust]A new global report by UNAIDS indicates that new HIV infections in Nigeria have declined by 35% in the past three years. (Source: AllAfrica News: HIV-Aids and STDs)
Nigeria: 2.6 Million Infected People to Access HIV/Aids Services
[Guardian]Abuja -THE International Federation of Red Cross and Red Crescent Societies (IFRC) has said the 2.6 million people living with HIV/AIDS in Benue and Cross River states are to benefit from improved access to quality treatment. (Source: AllAfrica News: HIV-Aids and STDs)
Tanzania: HIV/Aids Research Suffers Blow As Leading Don Dies
[Daily News]RESEARCH on HIV/ AIDS has suffered a setback following the death of a leading scientist, Dr Joep Lange (59) who was one of the passengers in the ill- fated Malaysia Airlines plane that crashed in eastern Ukraine on Thursday, claiming 298 lives. (Source: AllAfrica News: HIV-Aids and STDs)
Nigeria: Nigeria Achieves 35 Percent Drop in New HIV Infections
[Leadership]A new global report by the UNAIDS has revealed that new HIV infections have declined by 35% in the past three years in Nigeria. (Source: AllAfrica News: HIV-Aids and STDs)
Nigeria: 'Fight Against HIV Still Has a Long Way to Go'
[Leadership]Leading researchers have warned complacency about HIV and AIDS could derail the enormous progress achieved in the three-decade fight against the diseases. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Africa: New TERG Review Offers Window Into Challenges Inhibiting Impact in World's Most Fragile States
[GFO]Recommendations include wider collaboration, greater flexibility and easing of the co-financing requirements (Source: AllAfrica News: HIV-Aids and STDs)
Africa: Gaps Mark Several of the FM's First Concept Note Submissions
[GFO]CCMs given new guidance by Secretariat after Technical Review Panel asks for stronger submissions (Source: AllAfrica News: HIV-Aids and STDs)
South Africa: SA Clinicians Society Mourns Deaths On Flight 17
[Health-e]Dutch HIV expert Joep Lange, killed on Flight 17, was a 'friend of Africa' (Source: AllAfrica News: HIV-Aids and STDs)
Africa: At Conference, UNAIDS Chief Calls for End to 'Hypocrisy' in Fighting HIV/Aids
[UN News]The head of the United Nations agency dealing with HIV and AIDS today urged world leaders at an international conference in Australia to end the hypocrisy on sex and make treatment and reproductive health education universally available. (Source: AllAfrica News: HIV-Aids and STDs)
South Africa: HIV Diagnosis Unites Young Family
[Health-e]For some women, an HIV-positive diagnosis during pregnancy can spark domestic violence and abandonment. For Nokuzola Tholeduna, her diagnosis brought her young family together. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Africa: Youth Taking Lead at Aids 2014
[UNAIDS]The passion, dedication and commitment that young people are bringing to the AIDS response, driving the agenda and taking a leadership role, were celebrated by UNAIDS Executive Director Michel Sidibé in closing remarks at the AIDS 2014 youth preconference event. (Source: AllAfrica News: HIV-Aids and STDs)
Africa: People Living With HIV Lead Response to Discrimination
[Key Correspondents]When Malawian Martha Dzuwa was diagnosed with HIV, people in her community labelled her "a dead fellow walking". (Source: AllAfrica News: HIV-Aids and STDs)
Nigeria: Kaduna Distributes N7.5 Million Food to People Living With HIV
[Independent]The Kaduna State Action Committee on AIDS on Friday distributed food items worth N7.5 million as assistance to people living with HIV/AIDS. (Source: AllAfrica News: Health and Medicine)
HIV Prevention and Treatment Guidelines Released (FREE)
By Kelly Young Edited by Susan Sadoughi, MD, and André Sofair, MD, MPH The International AIDS Society-USA has released two sets of clinical guidelines on preventing and treating HIV, in conjunction with the AIDS 2014 conference and ? (Source: Physician's First Watch current issue)
Featured in NEJM Journal Watch: Mood Solemn in Melbourne as AIDS 2014 Starts (FREE)
By the NEJM Journal Watch Editors There is unquestionably a shadow cast over this year's international AIDS meeting here in Melbourne, writes ? (Source: Physician's First Watch current issue)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
The global burden of neurologic diseases
WHO categorizes causes of death and disability into (1) communicable diseases, maternal and perinatal conditions, and nutritional deficiencies; (2) non-communicable diseases (NCD); and (3) injuries. NCD are the leading cause of death and disability globally and are rising as a result of demographic and epidemiologic changes occurring in both developed and developing countries.1,2 Increasing life expectancies, unhealthy diet, physical inactivity, tobacco use, and harmful use of alcohol contribute to the growing incidence and prevalence of NCD, such as heart disease, stroke, diabetes, cancers, and chronic respiratory diseases. Deaths from communicable diseases, such as HIV/AIDS, tuberculosis, and malaria, are declining as a result of billions of dollars of annual international and domestic f...
Use of non?drug non?operative interventions by community?dwelling people with hip and knee osteoarthritis
Conclusion: Use of non?drug non?operative interventions was low amongst people with hip and knee OA. Our findings show evidence?practice gaps particularly with respect to the interventions most strongly recommended in clinical guidelines for hip and knee OA (weight loss and exercise). © 2014 American College of Rheumatology. (Source: Arthritis Care and Research)
The Week Ahead: Science Flows from AIDS Meeting
(MedPage Today) -- Science reports start to flow in earnest from the International AIDS Conference in Melbourne, Australia, although the tragedy of several delegates killed while en route to the meeting remains fresh. (Source: MedPage Today Public Health)
Joep Lange, The Physician-Scientist Before Medical Diplomat
The prominent Dutch HIV/AIDS figure made a significant global impact on treatment of the disease, especially in developing nations. But he was first a scientist at the front lines of a mysterious, just-discovered virus. (Source: Forbes.com Healthcare News)
At conference, UNAIDS chief calls for end to &#39hypocrisy&#39 in fighting HIV/AIDS
The head of the United Nations agency dealing with HIV and AIDS today urged world leaders at an international conference in Australia to end the hypocrisy on sex and make treatment and reproductive health education universally available. (Source: UN News Centre - Women, Children, Population)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
With Malaysia Airlines Crash, A Loss For AIDS Research
A number of scientists and others members of the AIDS research community died in the downing of Malaysia Airlines Flight 17 over Ukraine. NPR's Kelly McEvers speaks with journalist and editor in chief of HIV Plus magazine Diane Anderson-Minshall about the loss.&raquo; E-Mail This (Source: NPR Health and Science)
New HIV prevention recommendations combine biomedical, behavioral approaches
In an innovative approach to HIV prevention, an interdisciplinary group of experts has come together for the first time to lay out a framework of best practices to optimize the role of the clinician in achieving an AIDS-free generation. The recommendations are intended as guidelines for clinicians to implement a combined biomedical-behavioral approach to HIV care and prevention. They are based on a comprehensive review of data that was either published or presented at scientific conferences over the past 17 years. (Source: ScienceDaily Headlines)
HIV diagnosis rate falls by a third in U.S.: researchers
WASHINGTON (Reuters) - The annual rate of diagnosis with HIV, the virus that causes AIDS, fell by a third in the United States between 2002 and 2011, researchers reported on Saturday. (Source: Reuters: Health)
HIV Diagnoses Down in U.S., Except for Young Gay Males: CDC
Messages about safe sex may be falling on deaf ears, researcher notes Source: HealthDay Related MedlinePlus Pages: Gay, Lesbian, Bisexual and Transgender Health, HIV/AIDS, Health Disparities (Source: MedlinePlus Health News)
AIDS Conference Mourning Six Lost in Crash
(MedPage Today) -- MELBOURNE, Australia -- Six AIDS researchers and activists were beginning their journey to the International AIDS Conference here when their airliner was shot down over Ukraine. (Source: MedPage Today Infectious Disease)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Malawi: Sex Initiation Puts Girls At Risk for HIV
[VOA]In Malawi, almost a third of new HIV cases occur in women under the age of 30, in part because of traditional coming-of-age ceremonies that introduce young girls to sex, according to AIDS activists. (Source: AllAfrica News: Health and Medicine)
Africa: Persecution of Homosexuals Hinders Fight Against Aids
[Deutsche Welle]Life is dangerous for Africa's gays and lesbians, despite a resolution from the African Commission for Human Rights. The UN warns that the persecution of homosexuals is hindering the fight against AIDS. (Source: AllAfrica News: Health and Medicine)
AIDS researchers, activists believed among Malaysia plane victims
Malaysia Airlines Flight 17 tragedy believed to have taken the lives of many influential people working in science and activism for HIV/AIDS (Source: Health News: CBSNews.com)
Top HIV/AIDS Researchers Killed on Malaysian JetTop HIV/AIDS Researchers Killed on Malaysian Jet
An unconfirmed number of the world's leading HIV/AIDS researchers were among the 298 people killed on a Malaysian passenger jet that was shot down in eastern Ukraine. Medscape Medical News (Source: Medscape Hiv-Aids Headlines)
Combination treatment for Hep C associated with favorable response among patients with HIV
(The JAMA Network Journals) HIV-infected patients also infected with hepatitis C virus who received a combination of the medications sofosbuvir plus ribavirin had high rates of sustained HCV virologic response 12 weeks after cessation of therapy, according to a study in the July 23/30 issue of JAMA, a theme issue on HIV/AIDS. (Source: EurekAlert! - Infectious and Emerging Diseases)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Growth hormone analog may reduce risk of fatty liver disease in HIV-infected patients
(The JAMA Network Journals) In a preliminary study, HIV-infected patients with excess abdominal fat who received the growth hormone-releasing hormone analog tesamorelin for 6 months experienced modest reductions in liver fat, according to a study in the July 23/30 issue of JAMA, a theme issue on HIV/AIDS. Patients infected with HIV demonstrate a high prevalence of nonalcoholic fatty liver disease, estimated at 30 percent to 40 percent. (Source: EurekAlert! - Medicine and Health)
Offering option of initial HIV care at home increases use of antiretroviral therapy
(The JAMA Network Journals) Among adults in the African country of Malawi offered HIV self-testing, optional home initiation of care compared with standard HIV care resulted in a significant increase in the proportion of adults initiating antiretroviral therapy, according to a study in the July 23/30 issue of JAMA, a theme issue on HIV/AIDS. (Source: EurekAlert! - Medicine and Health)
Study examines rate of HIV diagnosis in US
(The JAMA Network Journals) The annual HIV diagnosis rate in the U.S. decreased more than 30 percent from 2002-2011, with declines observed in several key populations, although increases were found among certain age groups of men who have sex with men, especially young men, according to a study in the July 23/30 issue of JAMA, a theme issue on HIV/AIDS. (Source: EurekAlert! - Medicine and Health)
New HIV prevention recommendations combine biomedical and behavioral approaches
(Emory Health Sciences) In an innovative approach to HIV prevention, an interdisciplinary group of experts has come together for the first time to lay out a framework of best practices to optimize the role of the clinician in achieving an AIDS-free generation. (Source: EurekAlert! - Medicine and Health)
[Editorial] HIV: science and stigma
Today's issue of The Lancet is dedicated to HIV to coincide with the 20th International AIDS Conference ( AIDS 2014) in Melbourne, Australia (July 20?25, 2014). This year, the biennial meeting?the biggest global gathering of HIV scientists, health-care workers, and activists?has made stigma and discrimination one of its main concerns. Such an emphasis is sadly as necessary today as it was in the very early days of the disease. Worldwide, discriminatory environments that fuel HIV epidemics have remained entrenched in some countries and resurged in others. (Source: LANCET)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
[Comment] Antiretroviral therapy: stubborn limitations persist
The development in the mid-1990s of combination antiretroviral treatment (ART) for the management of HIV infections is one of medicine's greatest success stories. For individuals who can access and adhere to treatment at early stages of the infection, the risk of developing an AIDS-defining complication is vanishingly small. Treatment, however, does not fully restore health. Treated adults have a higher than expected risk of developing many non-AIDS complications, including cardiovascular disease and cancer. (Source: LANCET)
[Articles] Trends in underlying causes of death in people with HIV from 1999 to 2011 (D:A:D): a multicohort collaboration
Recent reductions in rates of AIDS-related deaths are linked with continued improvement in CD4 cell count. We hypothesise that the substantially reduced rates of liver disease and cardiovascular disease deaths over time could be explained by improved use of non-HIV-specific preventive interventions. Non-AIDS cancer is now the leading non-AIDS cause and without any evidence of improvement. (Source: LANCET)
[Seminar] HIV infection: epidemiology, pathogenesis, treatment, and prevention
HIV prevalence is increasing worldwide because people on antiretroviral therapy are living longer, although new infections decreased from 3·3 million in 2002, to 2·3 million in 2012. Global AIDS-related deaths peaked at 2·3 million in 2005, and decreased to 1·6 million by 2012. An estimated 9·7 million people in low-income and middle-income countries had started antiretroviral therapy by 2012. New insights into the mechanisms of latent infection and the importance of reservoirs of infection might eventually lead to a cure. (Source: LANCET)
Aids deaths tumble but rising resistance to HIV drugs threatens gains
Warning over growing resistance to antiretrovirals dampens hopes that Aids can be eliminated by 2030 Continue reading... (Source: Guardian Unlimited Science)
Leading AIDS Researcher, ?Always Traveling,? Is Killed on His Way to a Conference
Joep Lange, a pioneer from the early years of the AIDS crisis, played a key role in making H.I.V. treatments available in the developing world. (Source: NYT Health)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
This Week: Crash Devastates AIDS World, Pill Looks Matter
(MedPage Today) -- The deaths of HIV/AIDS researchers en route to an AIDS conference, a study highlighting the importance of a pill's appearance, and "assistant physicians" topped this week's news at MedPage Today. (Source: MedPage Today Cardiovascular)
A Pillar Of AIDS Research And Activism, Lost With Shot-Down Jet
Malaysia Airlines Flight 17 had been carrying several researchers and activists on their way to a global AIDS conference in Australia. Among them was Dr. Joep Lange, a leading researcher and former president of the International AIDS Society. He was a giant in the field and a mentor to many.&raquo; E-Mail This (Source: NPR Health and Science)
MH17 Malaysia Airlines crash: Tributes paid to world-renowned AIDS researcher on board stricken plane
Friends and colleagues of Professor Joep Lange, a world-renowned Aids researcher who was on board the stricken Malaysian flight, paid tribute yesterday to his ?tireless? efforts towards defeating HIV/Aids. (Source: The Independent - Science)
Remembrances of AIDS and HIV Workers Killed in Shot-Down Plane
HIV health workers, including one from the WHO, and at least one top AIDS researcher were among those killed when a Malaysia Airlines plane was shot down over Ukraine -- Read more on ScientificAmerican.com (Source: Scientific American - Official RSS Feed)
Interleukin-10 aids survival of cells transplanted to repair cardiac tissues after MI
Three groups of rats modeled with a myocardial infarction were treated with smooth muscle cell injections into the MI-damaged area of the heart in a new study. One group received unmodified autologous SMCs; another received unmodified allogenic SMCs; the last group received allogenic SMCs modified with interleukin 10 - a small, anti-inflammatory protein. The group receiving allogenic SMCs modified with IL-10 demonstrated cell survival, improved heart function, and protection against the host's rejection of the allogenic SMCs. (Source: ScienceDaily Headlines)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Leading AIDS Researcher Killed in Malaysia Airlines Flight 17 Crash
Dr. Joep Lange, a pioneer from the early years of the AIDS crisis, played a key role in making H.I.V. treatments available in the developing world. (Source: NYT Health)
HIV/AIDS Researchers, Officials En Route To AIDS 2014 Conference Lost In MH17 Crash
The international research community awaits confirmation of their worst fears that scores of colleagues enroute to the International AIDS Conference in Melbourne were among those who perished in the crash of Malaysian Airlines Flight 17. (Source: Forbes.com Healthcare News)
HIV/AIDS Researchers, Officials Perish In Malaysia Airlines MH17 Crash
The international research community awaits confirmation of their worst fears that scores of colleagues enroute to the International AIDS Conference in Melbourne were among those who perished in the crash of Malaysian Airlines Flight 17. (Source: Forbes.com Healthcare News)
100 Leading HIV/AIDS Researchers Killed on Malaysian Jet100 Leading HIV/AIDS Researchers Killed on Malaysian Jet
An estimated 100 of the world's leading HIV/AIDS researchers were among the 298 people killed on a Malaysian passenger jet that was shot down in eastern Ukraine. Medscape Medical News (Source: Medscape Hiv-Aids Headlines)
Changes in HIV Viral Load and CD4 in ART-Naive IndividualsChanges in HIV Viral Load and CD4 in ART-Naive Individuals
What causes short-term changes in HIV viral load and CD4 cell count in ART-naive individuals? AIDS (Source: Medscape Today Headlines)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Minutes silence held for MH17 victims headed to Melbourne AIDS conference
A candlelight vigil has been held in Melbourne in honour of the world's leading experts in the battle against HIV who were killed while travelling on Malaysia Airlines flight MH17 en route to an AIDS conference in the city. (Source: the Mail online | Health)
HIV Health Community Reels from Losses in Malaysia Airlines Tragedy
A top antiviral-therapy researcher, Joep Lange, was among the more than 100 researchers and advocates killed en route to the 20th International AIDS Conference in Australia -- Read more on ScientificAmerican.com (Source: Scientific American - Official RSS Feed)
Africa: Start Early, Start Now - Governments, Health Care Providers and NGOs Urged to Ramp Up Efforts to Meet the Needs of the Youngest Children in HIV-Affected Families
[PR Newswire]Melbourne, Australia -Statement from Kate Iorpenda, Chair of The Coalition for Children Affected by AIDS (Source: AllAfrica News: HIV-Aids and STDs)
IAC: Tragedy, Low Attendance Won't Stop Meeting
(MedPage Today) -- MELBOURNE, Australia -- The 2014 International AIDS Conference will go on as planned, despite the deaths of dozens of delegates aboard the airliner said to have been shot down over eastern Ukraine. (Source: MedPage Today Gastroenterology)
Africa: Get Tested, Get Treated - How Communities and Volunteers Can Play a Key Role in the Fight Against HIV
[IFRC]Millions of men and women around the world volunteer their time to help people living with HIV in their communities. But despite their valuable contribution, community health workers and volunteers often remain invisible, unacknowledged and under-utilised. As world leaders and HIV experts gather in Melbourne, Australia for the upcoming 2014 International AIDS Conference, the delegation from the International Federation of Red Cross and Red Crescent Societies (IFRC) is urging governments to ensure community (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
MH17 Malaysia Airlines crash: Tributes paid to world-renowned AIDs researcher on board stricken plane
Friends and colleagues of Professor Joep Lange, a world-renown AIDs researcher who was on board the stricken Malaysian flight, paid tribute yesterday to his ?tireless? efforts towards defeating HIV/Aids. (Source: The Independent - Science)
AIDS community mourns as top experts feared killed in downed plane
MELBOURNE/AMSTERDAM (Reuters) - The world of AIDS research was in shock on Friday after dozens of leading HIV experts were feared killed when a Malaysian plane was shot down over Ukraine, fuelling concerns that research on curing the disease could suffer. (Source: Reuters: Health)
Many Sexually Active U.S. Teens Not Tested for HIV: CDC
Only 22 percent of those at risk get screened, and researchers think complacency may be why (Source: Fertility News - Doctors Lounge)
AIDS Activists Stunned by Malaysian Air Crash
MELBOURNE (MedPage Today) -- Many HIV/AIDS researchers and activists were on board Malaysian Airways MH17, the passenger jet that was knocked out of the sky Thursday over Ukraine. (Source: MedPage Today Public Health)
Many Sexually Active U.S. Teens Not Tested for HIV: CDC
Only 22 percent of those at risk get screened, and researchers think complacency may be why Source: HealthDay Related MedlinePlus Pages: HIV/AIDS, Health Screening, Teen Sexual Health (Source: MedlinePlus Health News)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Zambia: National Aids Council Gets New DG
[Times of Zambia]RANKING Zambia as one of the top six countries globally in rapid reduction of new HIV infections is an indication that the nation is poised to win the fight within this generation, National AIDS Council (NAC) board chairperson Joshua Banda has said. (Source: AllAfrica News: HIV-Aids and STDs)
WHO Statement on Mr Glenn Thomas, WHO Media Officer who died in the MH17 plane
It is with deep sadness that we have to inform you that WHO lost one of our colleagues on the Malaysian Airlines crash yesterday. Glenn Thomas from the Department of Communications was travelling to the International AIDS Conference in Australia. His twin sister says he died doing what he loved. Glenn had been with WHO for more than a decade. He came here from the BBC and spent many years providing communications support to the TB Department. Since 2012 he had been working on the media team in DCO, regularly hosting press conferences and working with you at the Palais and with other journalists to promote the work of WHO. Glenn will be remembered for his ready laugh and his passion for public health. (Source: WHO news)
Liberia: In Liberia, One Aids Victim Fighting Through Trauma, Pain
[FrontPageAfrica]Monrovia -As Liberia emerges out of fourteen years of civil conflict, many people still have to live with their own wars, ranging from trauma to sexual gender based violence and from personal wars to family wars. While others are internal and external conflicts to land disputes, etc. But Sue Francis, not her real name, has to fight her own traumatic war that has left her pains and sad memories that is hard to forget but rather live with. "He was the first because he was the general, and in the presence of my father, (Source: AllAfrica News: HIV-Aids and STDs)
New Quality Measures Proposed for Medicare ACO ProgramNew Quality Measures Proposed for Medicare ACO Program
CMS would require organizations to report on 37 quality measures; outcomes and chronic conditions are emphasized. Medscape Medical News (Source: Medscape Hiv-Aids Headlines)
Aids researchers on crashed plane
Dozens of passengers on the Malaysia Airlines plane were thought to have been heading to a major international Aids conference in Australia. (Source: BBC News | Health | UK Edition)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Nigeria: Nigeria Records 35 Percent Reduction in New HIV Infections
[Vanguard]Abuja -United Nations Programme on HIV and AIDS Country Director in Nigeria, Dr. Bilali Camara, has said that a new global report by UNAIDS showed that new HIV infections in Nigeria had declined by 35 per cent in the past three years. (Source: AllAfrica News: HIV-Aids and STDs)
South Africa: 19,000 HIV/Aids Workers Trained for the Frontlines
[IFP]Today the Children with HIV Association (CHIVA) celebrates ten years of mentoring and training healthcare workers to treat HIV/Aids in children and adolescents. (Source: AllAfrica News: HIV-Aids and STDs)
HIV/AIDS field shocked by death of leading researcher in MH17 crash
Joep Lange and at least five others heading to Melbourne meeting were on board downed plane (Source: ScienceNOW)
Rwanda: Deaths From Aids-Related Causes Decline Drastically
[New Times]The United Nations announced Wednesday that Aids-related deaths and new HIV infections fell by over a third in a decade. (Source: AllAfrica News: Health and Medicine)
MH17 conspiracy theories emerge: Fake passports, AIDS researchers, false flags and more
(NaturalNews) The shooting down of Malaysia Airlines MH17 over Ukraine is a catastrophic event resulting in the loss of 295 lives (280 passengers and 15 crew). Details are still emerging about what really happened, but Netizens are already fronting various theories of what may have... (Source: NaturalNews.com)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Nigeria: New UN Report Indicts Nigeria, Others Over HIV/Aids Increase Amid Global Decline
[This Day]In a new report by the United Nations AIDS (UNAIDS) Thursday in Geneva, Switzerland, Nigeria and two other African countries have been indicted over increasing cases of HIV/AIDS pandemic in their countries amid overall global decline of the disease. (Source: AllAfrica News: HIV-Aids and STDs)
Uganda: HIV Thrives in Fishing Villages
[Observer]A new survey by the Joint Clinical Centre in Kabarole district suggests the HIV/Aids prevalence rate in fishing communities on landing sites has risen. (Source: AllAfrica News: Health and Medicine)
Rwanda: Global Fund Lauds MoH Financial Control System
[New Times]The global Fund to fight Aids, Tuberculosis and Malaria, commonly known as Global Fund, has hailed government for putting in place effective control measures to ensure maximum utilisation of donor funds allocated to the health sector. (Source: AllAfrica News: Health and Medicine)
Causes of death shifting in people with HIV
HIV-positive adults in high income countries face a substantially reduced risk of death from AIDS-related causes, cardiovascular disease, and liver disease compared with a decade ago, according to a large international study. Although deaths from most causes declined over the study period, there was no reduction in death rates from non-AIDS cancers which remained stable over time (1.6 deaths per 1000 years 1999-2000 to 2.1 in 2009-2011). Non-AIDS cancers are now the leading cause of non-AIDS deaths in people with HIV, accounting for 23% of all deaths. (Source: ScienceDaily Headlines)
Prioritizing children and families at AIDS 2014
(Elizabeth Glaser Pediatric AIDS Foundation) Experts from the Elizabeth Glaser Pediatric AIDS Foundation will give oral presentations, moderate conference events, and exhibit a variety of educational posters and abstracts related to ending AIDS in children. (Source: EurekAlert! - Medicine and Health)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Interleukin-10 aids survival of cells transplanted to repair cardiac tissues after MI
(Cell Transplantation Center of Excellence for Aging and Brain Repair) Three groups of rats modeled with a myocardial infarction were treated with smooth muscle cell injections into the MI-damaged area of the heart. One group received unmodified autologous SMCs; another received unmodified allogenic SMCs; the last group received allogenic SMCs modified with interleukin 10 - a small, anti-inflammatory protein. The group receiving allogenic SMCs modified with IL-10 demonstrated cell survival, improved heart function, and protection against the host's rejection of the allogenic SMCs. (Source: EurekAlert! - Medicine and Health)
AIDS Researchers Among Those Feared Dead in Malaysia Flight Crash
Several researchers and participants traveling to a major AIDS conference in Melbourne, Australia were believed to be among the victims of the downing of a Malaysia Airlines flight in Ukraine. (Source: WSJ.com: Health)
Those With HIV Living Longer, International Study Finds
Deaths from AIDS-related causes, heart disease and liver disease have all dropped (Source: WebMD Health)
Non-AIDS Cancers Cause as Many Deaths as AIDS in HIV-Infected Patients (FREE)
By Amy Orciari Herman Edited by André Sofair, MD, MPH, and William E. Chavey, MD, MS Non-AIDS-related cancers are now responsible for as many deaths as AIDS among HIV-infected patients, according to a Lancet study.Researchers followed nearly 50,000 HIV-infected patients receiving ? (Source: Physician's First Watch current issue)
"Mississippi Baby" Now Has Detectable HIV, Researchers Find
&quot;The child known as the 'Mississippi baby'&mdash;an infant seemingly cured of HIV that was reported as a case study of a prolonged remission of HIV infection in The&nbsp;New England Journal of Medicine last fall&mdash;now has detectable levels of HIV after more than two years of not taking antiretroviral therapy without evidence of virus, according to the pediatric HIV specialist and researchers involved in the case. &quot;'Certainly, this is a disappointing turn of events for this young child, the medical staff involved in the child&rsquo;s care, and the HIV/AIDS research community,' said NIAID Director Anthony S. Fauci, M.D. 'Scientifically, this development reminds us that we still have much more to learn about the intricacies of HIV infection and where the virus hides in the body...<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Study Suggests That Low Levels of HIV-1 RNA Detected in the Cerebrospinal Fluid After Up to 10 Years of Suppressive Therapy Are Associated With Local Immune Activation
We examined the frequency and magnitude of persistent low-level HIV-1 RNA in CSF and its relation to the central nervous system (CNS) immune activation. &hellip; &quot;CSF and plasma HIV-1 RNA were measured using the single-copy assay with a detection limit of 0.3 copies/ml in 70 CSF and 68 plasma samples from 45 treated HIV-1-infected patients with less than 40 copies/ml of HIV-1 RNA in both fluids by standard clinical assays. &hellip; &quot;CSF HIV-1 RNA was detected in 12 of the 70 CSF samples (17%) taken after up to 10 years of suppressive therapy, compared to 39 of the 68 plasma samples (57%) with a median concentration of less than 0.3 copies/ml in CSF compared to 0.3 copies/ml in plasma (P&lt;0.0001). &hellip; &quot;Low-level CSF HIV-1 RNA and its association with elevated CSF ne...
Electronic cigarettes are at least as effective as nicotine patches for smoking cessation
Commentary on: Bullen C, Howe C, Laugesen M, et al.. Electronic cigarettes for smoking cessation: a randomised controlled trial. Lancet 2013;382:1629&ndash;37. Context Electronic cigarettes (e-cigarettes) contain refined nicotine dissolved in propylene glycol, glycerine or other humectants, which is vaporised with a battery-powered heating element, activated by suction or manually, and delivered into the airways.1 E-cigarettes have been shown to reduce craving and withdrawal symptoms in abstinent smokers and, as nicotine is delivered without tobacco combustion, are thought to be substantially safer than cigarettes.2 While e-cigarette use is rapidly increasing, relatively little is known about their efficacy for smoking cessation, particularly compared with established nicotine-containing p...
Brief, patient-centred risk-reduction counselling at the time of a rapid HIV test does not affect subsequent acquisition of sexually transmitted infections
Commentary on: Metsch LR, Feaster DJ, Gooden L, et al. Effect of risk-reduction counseling with rapid HIV testing on risk of acquiring sexually transmitted infections: the AWARE randomised clinical trial. JAMA 2013;310:1701&ndash;10. Context HIV testing and counselling (HTC) is a key entry point to care and treatment services for those who test HIV positive, and to prevention services for those who test HIV negative. Over the past few decades, HTC has been scaled up globally through client-initiated and provider-initiated testing services. The WHO recommends counselling as an integral part of all HIV testing strategies: &lsquo;Testing services must be accompanied by appropriate and high-quality pretest information or pretest counselling and post-test counselling&rsquo;.1 However, the natur...
Women with HIV infection on antiretroviral therapy with low viral loads can safely opt for vaginal delivery in the absence of obstetrical risk factors
Commentary on: Briand N, Jasseron C, Sibiude J, et al.. Cesarean section for HIV-infected women in the combination antiretroviral therapies era, 2000&ndash;2010. Am J Obstet Gynecol 2013;209:335e1&ndash;12. Context The risk of mother-to-child HIV transmission (MTCT) is related to the infant's exposure to HIV-infected maternal blood during birth. Studies published in 1999 have shown a protective effect from elective caesarean section (ECS) in reducing the risk of MTCT.1 2 However, these studies were conducted prior to use of combination antiretroviral therapy (cART) in pregnancy becoming widespread. Antiretroviral therapy through maximum suppression of maternal viral load is the most effective means of preventing MTCT.3 Whether there is any additional benefit from ECS for mothers with low v...
Toward Minimum Standards for Certifying Patient Decision Aids: A Modified Delphi Consensus Process
Conclusions. This study provides preliminary certification criteria for PDAs. Scoring and rating processes need to be tested and finalized. However, the process of appraising the quality of the clinical evidence reported by the PDA should be used to complement these criteria; the proposed standards are designed to rate the quality of the development process and shared decision-making design elements, not the quality of the PDA&rsquo;s clinical content. (Source: Medical Decision Making)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Sample Size and Power When Designing a Randomized Trial for the Estimation of Treatment, Selection, and Preference Effects
Conclusions. With the growing interest in understanding treatment choices and with the use of decision aids, well-designed and adequately powered 2-stage randomized trial designs offer the opportunity to determine the effects of participants&rsquo; preferences. Our sample size formulas will help future studies ensure that they have adequate power to detect selection and preference effects. (Source: Medical Decision Making)
Addressing patients' psychosocial concerns regarding hearing aids within audiology appointments for older adults.
Conclusions: Older adults' psychosocial concerns regarding hearing aids may not always be sufficiently addressed within audiology appointments. A greater emphasis on emotionally-focused communication within audiology could result in improved outcomes from hearing health care services. PMID: 25036799 [PubMed - as supplied by publisher] (Source: American Journal of Audiology)
Active surveillance of adverse events following childhood immunization in Singapore.
CONCLUSIONS: Hospital-based active surveillance can enhance signal detection and follow-up investigations of AEFI. Subsequently, public health bodies are better equipped to maintain public confidence in vaccination programmes and physicians are able to provide relevant advice to parents. It also allows for a better understanding of risk-benefit ratios of specific vaccines and aids the generation of public health vaccination policy. PMID: 25045811 [PubMed - as supplied by publisher] (Source: Vaccine)
Vaccines: HIV vaccine failure due to induction of immune suppressors?
Nature Reviews Drug Discovery 13, 574 (2014). doi:10.1038/nrd4398 Author: Alexandra Flemming An effective therapeutic and/or prophylactic vaccine against HIV would be the ultimate weapon against the global AIDS pandemic. However, although it has been shown that vaccine-induced T cell responses can control HIV replication, the formulation of effective vaccines has been exceptionally challenging. Now, writing in (Source: Nature Reviews Drug Discovery)
Those with HIV Living Longer, International Study Finds
Deaths from AIDS-related causes, heart disease and liver disease have all dropped Source: HealthDay Related MedlinePlus Pages: HIV/AIDS, International Health, Living with HIV/AIDS (Source: MedlinePlus Health News)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Concept Clearance » Monitoring Antiretroviral Adherence to Improve HIV Treatment and Prevention
The aims of this initiative are to improve treatment for HIV/AIDS and HIV prevention by advancing: (i) Methods for real-time or prospective monitoring of oral ARV adherence (antiretroviral therapy [ART], pre-exposure prophylaxis [PrEP]); (ii) Timely and targeted delivery of interventions when adherence monitoring reveals deficits; and, (iii) Predictive models that estimate current risk of viral breakthrough or HIV infection for a given individual based on ART adherence monitoring and related data. (Source: National Institute of Mental Health)
Brown fat found to be at the root of cancer-related wasting syndrome
Many patients with advanced stages of cancer, AIDS, tuberculosis, and other diseases die from a condition called cachexia, which is characterized as a 'wasting' syndrome that causes extreme thinness with muscle weakness. Cachexia is the direct cause of roughly 20 percent of deaths in cancer patients. While boosting food intake doesn't help, and no effective therapies are available, new research points to a promising strategy that may stimulate weight gain and muscle strength. (Source: ScienceDaily Headlines)
AIDS epidemic could be 'wiped out by 2030'
AIDS-related deaths worldwide dropped to 1.5 million last year, from 1.7 million the year before - the sharpest annual decline since the epidemic's peak, the UN says. (Source: the Mail online | Health)
Research on persons with HIV/AIDS not taking medication, not engaged in care
A new study describes factors believed to contribute to the critical public health issues of persons with HIV/AIDS not complying with treatment or care. The study has a particular focus on African American and Latino/Hispanic people with HIV/AIDS, the racial/ethnic groups most affected by HIV/AIDS. (Source: ScienceDaily Headlines)
Community Resistance and Transmitted HIV Drug ResistanceCommunity Resistance and Transmitted HIV Drug Resistance
Could HIV-1 community drug resistance predict the prevalence of transmitted drug resistance? HIV Medicine (Source: Medscape Today Headlines)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Dolutegravir: Clinical Efficacy and Role in HIV TherapyDolutegravir: Clinical Efficacy and Role in HIV Therapy
A comprehensive overview of the integrase-inhibitor dolutegravir, which shows some novel and intriguing characteristics. What's its place in the HIV drug armamentarium? Therapeutic Advances in Chronic Disease (Source: Medscape Today Headlines)
Africa: Factbox - New HIV Infections Fall As Aids Epidemic Stabilises
[AlertNet]London -If the world could rally to end the AIDS epidemic by 2030, 18 million new HIV infections and 11.2 million AIDS-related deaths would be averted, the United Nations said on Wednesday. (Source: AllAfrica News: Health and Medicine)
Africa: Aids Deaths Fall, but Millions Unaware of HIV-Positive Status - UN
[UN News]While showing a downward trend in AIDS-related deaths, a new United Nations report out today warns that19 million of the 35 million people living with the virus globally do not know their HIV-positive status and therefore, ending the AIDS epidemic by 2030 will require smart scale-up to close the gap. (Source: AllAfrica News: Health and Medicine)
Namibia: 73 000 Face ARV Resistance
[Namibian]MORE than 73 000 people on antiretroviral (ARV) therapy in some parts of the country run the risk of becoming drug resistant after they were taken off their prescribed medication because of shortages. (Source: AllAfrica News: HIV-Aids and STDs)
Zimbabwe: Zimbabwe Accounts for Three Per Cent of New Global HIV Infections
[New Zimbabwe]ZIMBABWE is one of 15 countries in the world accounting for 75 percent of new HIV infections worldwide, according to a new report by the United Nations Programme on HIV and AIDS. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Nigeria: Nigeria, S'Africa, Uganda Account for 48 Per Cent New HIV Infections
[Guardian]THE Federal Government's efforts through the National Agency for the Control of AIDS (NACA) notwithstanding, Nigeria is one of the 15 countries accounting for over 75 per cent of the 2.1 million new Human Immuno-deficiency Virus (HIV) infections that occurred in 2013. (Source: AllAfrica News: HIV-Aids and STDs)
AIDS Epidemic May Be Subsiding: Report
Title: AIDS Epidemic May Be Subsiding: ReportCategory: Health NewsCreated: 7/16/2014 1:35:00 PMLast Editorial Review: 7/17/2014 12:00:00 AM (Source: MedicineNet HIV General)
Epicardial fat is associated with duration of antiretroviral therapy and coronary atherosclerosis
Objective:Cytokines released by epicardial fat are implicated in the pathogenesis of atherosclerosis. HIV infection and antiretroviral therapy have been associated with changes in body fat distribution and coronary artery disease. We sought to determine whether HIV infection is associated with greater epicardial fat and whether epicardial fat is associated with subclinical coronary atherosclerosis. Design:We studied 579 HIV-infected and 353 HIV-uninfected men aged 40?70 years with noncontrast computed tomography to measure epicardial adipose tissue (EAT) volume and coronary artery calcium (CAC). Total plaque score (TPS) and plaque subtypes (noncalcified, calcified, and mixed) were measured by coronary computed tomography angiography in 706 men. Methods:We evaluated the association betwee...
Geographic distribution of HIV stigma among women of childbearing age in rural Kenya
Conclusion:Our results may point to differences in the underlying social processes motivating each form of HIV stigma. Externalized stigma may be driven more by cultural beliefs disseminated within communities, whereas internalized stigma may be the result of individual-level characteristics outside the domain of community influence. These data may inform community-level interventions to decrease HIV-related stigma, and thus impact the HIV epidemic. (Source: AIDS)
Nigeria: Red Cross, UNAIDS Seek Support to Improve Access to HIV Care
[Guardian]THE International Federation of Red Cross and Red Crescent Societies (IFRC), in collaboration with Joint United Nation Programme on AIDS (UNAIDS), has called on stakeholders in the health sector and partners to join them in the implementation of an intensive Human Immuno-deficiency Virus (HIV)/Acquired Immune Deficiency Syndrome (AIDS) campaign to improve access to service for 2.6 million people in Benue and Cross Rivers states. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
NYU research on persons w/ HIV/AIDS not taking medication and not engaged in care
(New York University) The study describes factors believed to contribute to these critical public health issues, with a focus on African American and Latino/Hispanic PLHAs, the racial/ethnic groups most affected by HIV/AIDS. (Source: EurekAlert! - Medicine and Health)
Brown fat found to be at the root of cancer-related wasting syndrome
(Cell Press) Many patients with advanced stages of cancer, AIDS, tuberculosis, and other diseases die from a condition called cachexia, which is characterized as a 'wasting' syndrome that causes extreme thinness with muscle weakness. Cachexia is the direct cause of roughly 20 percent of deaths in cancer patients. While boosting food intake doesn't help, and no effective therapies are available, new research points to a promising strategy that may stimulate weight gain and muscle strength. (Source: EurekAlert! - Cancer)
Biomarker discovery may lead to new HIV treatment
(WHITECOAT STRATEGIES, LLC) Further analysis of a Phase II study of therapeutic HIV vaccine candidate Vacc-4x revealed a potential biomarker associated with participants who experienced a more profound viral load reduction after receiving the vaccine. The results of this exploratory, ad hoc, subset analysis by St George's, University of London and Bionor Pharma were announced today at the AIDS 2014 Conference in Melbourne, Australia. (Source: EurekAlert! - Infectious and Emerging Diseases)
High rates of violence suffered by unstably housed women in San Francisco
(University of California - San Francisco) 'We looked at all types of violence -- physical, sexual and emotional. We expected to find higher rates than those reported in the general population, but we were surprised at the amount of harm inflicted upon this incredibly vulnerable population of women and the multitude of perpetrators,' said study principal investigator, Elise D. Riley, PhD, associate professor of medicine at the UCSF HIV/AIDS Division at San Francisco General Hospital and Trauma Center. (Source: EurekAlert! - Infectious and Emerging Diseases)
Kidney Dysfunction Among HIV-Infected Children in Latin America and the Caribbean
AIDS Research and Human Retroviruses , Vol. 0, No. 0. (Source: AIDS Research and Human Retroviruses)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
AIDS Epidemic May Be Subsiding: Report
Number of new infections, deaths declining, while more with HIV getting lifesaving medications (Source: Fertility News - Doctors Lounge)
Sensory hair cell regeneration in the zebrafish lateral line
Abstract Damage or destruction of sensory hair cells in the inner ear leads to hearing or balance deficits that can be debilitating, especially in older adults. Unfortunately, the damage is permanent, as regeneration of the inner ear sensory epithelia does not occur in mammals. Zebrafish and other non?mammalian vertebrates have the remarkable ability to regenerate sensory hair cells and understanding the molecular and cellular basis for this regenerative ability will hopefully aid us in designing therapies to induce regeneration in mammals. Zebrafish not only possess hair cells in the ear but also in the sensory lateral line system. Hair cells in both organs are functionally analogous to hair cells in the inner ear of mammals. The lateral line is a mechanosensory system found in most aqu...
Sepsis severe or septic shock: outcome according to the immune status and immunodeficiency profile.
Conclusion:immunodeficiency is common in patients with severe sepsis or septic shock. Despite a similar crude mortality, immunodeficiency was associated with an increased risk of short-term mortality after multivariate analysis. Neutropenia and specific, but not all, profiles of immunodeficiency were independently associated with an increased risk of death. Objective: to evaluate the influence of the immune profile on the outcome at day 28 (D28) of patients admitted in ICU for septic shock or severe sepsis. Materials and Methods: we conducted an observational study using a prospective multicenter database, and included all patients admitted in 11 ICUs for severe sepsis or septic shock, from January 1997 to August 2011. Seven profiles of immunodeficiency were defined. The prognostic...
Falls and Use of Assistive Devices in Stroke Patients with Hemiparesis: Association with Balance Ability and Fall Efficacy.
CONCLUSIONS: Stroke patients with fall experience and walking aids might be considered at increased risk of falling. CLINICAL RELEVANCE: Preventive measures for individuals using walking aids may be beneficial in reducing the fall rate of community-dwelling stroke patients. PMID: 25042606 [PubMed - as supplied by publisher] (Source: Rehabilitation Nursing)
Rehabilitation versus Nursing Home Nurses' Low Back and Neck-Shoulder Complaints.
CONCLUSIONS: Differences between the nurse groups as to work tasks might be a reason for differences in musculoskeletal complaints. Further comparisons between nurses working in different fields might reveal more accurate potential risk factors for work-related musculoskeletal complaints. CLINICAL RELEVANCE: Instruction for static/awkward posture avoidance, by using mechanical aids and designing a friendlier environment, should be part of a nursing staff injury prevention strategy. PMID: 25042522 [PubMed - as supplied by publisher] (Source: Rehabilitation Nursing)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Update from Team Himiti!
We moved into the village on the June 28th ready to educate the villagers of Himiti about HIV/AIDS. On the very first day we met our host families and spent the day getting used to our environment. On the second day in the village we were able to introduce ourselves to a church of more than 150 members and we had our first teaching at another church. Throughout the week, while doing the community surveys, we got to explore the landscape of Himiti as we hiked mountains to get to all the sub-villages. The view from high up included the whole village and the hippo lake (Lake Babati). Unfortunately, Grant and Enoch got sick on the third day for two days and became all too acquainted with the well-known Traveler?s Disease. The next day Emily followed suit. This was not a good start for the gr...
Hello from Bonga Village!
Greetings from the SIC volunteers in Bonga Village! Our team, self-proclaimed the Bonga Blue, includes Kimmi, Emily W., Nicko, Zach, Emmy and Hannah Mac. We have been hard at work the past two weeks, as we?ve been reaching out to the many different community and student groups Bonga has to offer. There are two primary and two secondary schools in addition to the three churches, two mosques, and the clinic. Bonga is a busy village where all sorts of people from around the area come to go to market, to seek treatment at the clinic, and to attend school &#8211; as it is where the only two secondary schools are located in the ward. So far, the people have been incredibly receptive to our teachings. We already have two testing days planned for the village, with the first coming up this week a...
VP2 Update: Greetings from Haraa!
We get to Haraa by driving up. Not up some and then down some. Just up. We arrived at the top of a mountain that would be our new home for the summer. At first we could not speak while we walked around the village &#8211; the seemingly monstrous hills took our breath while leaving us with only a grunt here and there. The &#8220;shortcuts&#8221; were even worse. Perhaps the translation is off because we thought shortcut meant short and easy! However, in just two weeks we&#8217;ve fallen in love with this place, and everything about it, including our epic hikes to get just about anywhere! What&#8217;s more, each of us has found something of our own in Haraa. Rashidi&#8217;s found his spot as a hot shot on the football (soccer) team &#8211; the guys are probably already trying to recruit him ...
AIDS deaths decline, but not HIV cases
The United Nations has set targets to reduce deaths and new cases of AIDS by 90 percent by 2030, but some health officials say goal is unrealistic (Source: Health News: CBSNews.com)
Vaccination in HIV-Infected Adults
AIDS Patient Care and STDs , Vol. 0, No. 0. (Source: AIDS Patient Care and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Identification of a Novel HIV-1 Second-Generation Recombinant Form (CRF01_AE/CRF07_BC) in Jilin, China
AIDS Research and Human Retroviruses , Vol. 0, No. 0. (Source: AIDS Research and Human Retroviruses)
Habitual Nutrient Intake in HIV-Infected Youth and Associations with HIV-Related Factors
AIDS Research and Human Retroviruses , Vol. 0, No. 0. (Source: AIDS Research and Human Retroviruses)
HIV-1 Nef Protein Carries Multiple Epitopes Suitable for Induction of Cellular Immunity for an HIV Vaccine in Africa
AIDS Research and Human Retroviruses , Vol. 0, No. 0. (Source: AIDS Research and Human Retroviruses)
AIDS deaths fall, but millions unaware of HIV-positive status, warns UN report
While showing a downward trend in AIDS-related deaths, a new United Nations report out today warns that19 million of the 35 million people living with the virus globally do not know their HIV-positive status and therefore, ending the AIDS epidemic by 2030 will require smart scale-up to close the gap. (Source: UN News Centre - Health, Poverty, Food Security)
AIDS Epidemic May Be Subsiding: Report
Number of new infections, deaths declining, while more with HIV getting lifesaving medications (Source: WebMD Health)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Tactile Interface Technology for People with Vision Disabilities
Imagine feeling a slimy jellyfish, a prickly cactus or map directions on your iPad mini Retina display, because that?s where tactile technology is headed. But you?ll need more than just an index finger to feel your way around. (Source: Disabled World)
AIDS Epidemic May Be Subsiding
Number of new infections, deaths declining, while more with HIV getting lifesaving medications Source: HealthDay Related MedlinePlus Pages: HIV/AIDS, HIV/AIDS Medicines, International Health (Source: MedlinePlus Health News)
Aids can be 'under control by 2030'
The Aids epidemic can be brought under control by 2030, according to a report by the United Nations Aids agency. (Source: BBC News | Health | UK Edition)
Malawi: Trying to Reach Deaf and Blind Community With HIV Messaging
[GFO]Tailoring outreach to people with disabilities a goal for advocates under NFM (Source: AllAfrica News: HIV-Aids and STDs)
Cote d'Ivoire: Sexual Violence Fuels HIV Epidemic
[Key Correspondents]Three years after the Ivory Coast post-election crisis of 2010 ended, rape is still a major problem and the security situation for Ivorian women remains bleak. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
South Africa: Fight Against HIV, TB to Be Intensified in Prisons
[SAnews.gov.za]Pretoria -The Department of Justice and Correctional Services will intensify the fight against HIV and Tuberculosis in prisons, says Minister Michael Masutha. (Source: AllAfrica News: HIV-Aids and STDs)
Zambia: Disabled Needing HIV Services Face Discrimination - Report
[AlertNet]In Zambia, where disability is often considered a punishment inflicted by evil spirits, nearly one million people with disabilities are struggling to access HIV prevention or testing services or treatment, a rights group said. (Source: AllAfrica News: HIV-Aids and STDs)
Global AIDS epidemic can be controlled by 2030, U.N. says
LONDON (Reuters) - New HIV infections and deaths from AIDS are decreasing, the United Nations said on Wednesday, making it possible to control the epidemic by 2030 and eventually end it "in every region, in every country". (Source: Reuters: Health)
Zambia: People With Disabilities Left Behind in HIV Response
[HRW]The nearly two million people with disabilities in Zambia face significant barriers to HIV prevention, testing, and treatment, Human Rights Watch said in a report released today. While the Zambian government has made considerable progress scaling up its response to HIV generally, few programs are accessible to people with disabilities and social stigma prevents their access to HIV services on an equal basis with others. (Source: AllAfrica News: HIV-Aids and STDs)
Zambia: Deaf, and Shut Out from HIV Information
[HRW]Faith learned she was HIV positive two years ago, after giving birth to her daughter. The Zambian government prides itself on its HIV prevention outreach, and every pregnant woman is supposed to be tested for the virus, to prevent passing it on to their babies. But Faith, now 25, is deaf, and was never tested before the baby was born. Nor did she receive even basic information about HIV. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Zimbabwe: Boy, 10, Accidentally Killed Over HIV Meds
[New Zimbabwe]A MATABELELAND South man slapped his HIV positive ten year-old brother after the boy refused to take his medication. The boy however, fell headlong onto a pile of bricks and died, the High Court heard in Bulawayo this week. (Source: AllAfrica News: HIV-Aids and STDs)
Zimbabwe: Ex-Convict Sets Girlfriend Ablaze for 'Infecting' Him With HIV
[New Zimbabwe]AN ex-convict who was released from prison in February this year under the presidential amnesty programme set his girlfriend on fire for allegedly 'infecting' him with HIV. (Source: AllAfrica News: HIV-Aids and STDs)
Uganda: Mississipi Baby 'Cured'of HIV Turns Positive
[Observer]A US toddler who was thought to have been cured from HIV has been found to still harbour the virus. (Source: AllAfrica News: HIV-Aids and STDs)
Uganda: Ugandan Doctor Re-Elected to Global HIV Body
[Observer]Dr Alex Muganzi, a doctor for HIV/Aids patients and head of the Infectious Diseases Institute (IDI) outreach department, has been re-elected to the International Aids Society (IAS) governing council as the Africa representative. (Source: AllAfrica News: Health and Medicine)
Nigeria: Stakeholders Task C'river Govt On Anti-HIV/Aids Campaign
[Independent]Calabar Stakeholders in the fight against the spread of HIV/AIDS in Cross River State want the state government to evolve new ways of funding the campaign against the scourge in the state. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
'UK teens unaware of HIV or Aids'
There's a call for better education for 12 to 17-year-olds about how they can catch HIV and Aids. (Source: BBC News | Health | UK Edition)
HIV-2 viral tropism influences CD4+ T cell count regardless of viral load
Conclusions The presence of X4-tropic viruses in HIV-2 infection is associated with low CD4+ cell counts, regardless of antiretroviral treatment. Along with CD4+ cell counts, viral tropism testing may assist decisions about when to initiate antiretroviral therapy in HIV-2-infected individuals. (Source: Journal of Antimicrobial Chemotherapy)
Temporal trends in the discontinuation of first-line antiretroviral therapy
Conclusions Discontinuation rates of first-line therapy have decreased over time, but are still quite high even for the latest drug combinations. In the most recent era, younger women on a PI regimen and those not achieving optimal adherence had the highest risk of discontinuing first-line antiretroviral therapy. (Source: Journal of Antimicrobial Chemotherapy)
This is My Story: participatory performance for HIV and AIDS education at the University of Malawi
Discussion (PACED) method engages artists and people living with HIV and AIDS (PLWHA) to create a performance that encourages community dialog about HIV and AIDS and empowers PLWHA. &lsquo;This is My Story&rsquo; was a program at the University of Malawi, Chancellor College, which adapted the PACED approach for university students. A qualitative evaluation conducted 1 year later among students and PLWHA participants and audience members demonstrated retention of the following themes: (i) trust in a relationship and how it affects women,(ii) equality for PLWHA and (iii) life after HIV and AIDS. All of the PLWHA and 90.9% of student participants reported a greater sense of empowerment. Of the audience members, 82.1% discussed the performance with friends and family. We thus present the PACED...
The effectiveness of HIV/AIDS school-based sexual health education programmes in Nigeria: a systematic review
HIV/AIDS is one of the most important public health challenges facing Nigeria today. Recent evidence has revealed that the adolescent population make up a large proportion of the 3.7% reported prevalence rate among Nigerians aged 15&ndash;49 years. School-based sexual health education has therefore become an important tool towards fighting this problem. This systematic review assesses the efficacy of these educational programmes and examines how future programmes and their evaluations can improve. Primary literature published between January 2002 and May 2012, which measured sexual health outcomes among school-based Nigerians before and after a sexual health education programme was delivered, was identified. All seven studies that met the inclusion and exclusion criteria showed there had b...<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Health information technology interventions enhance care completion, engagement in HIV care and treatment, and viral suppression among HIV-infected patients in publicly funded settings.
We examined the effect of six health information technology (HIT) interventions in a Ryan White-funded Special Projects of National Significance (SPNS) on care completion services, engagement in HIV care, and viral suppression. METHODS: Interventions included use of surveillance data to identify out-of-care individuals, extending access to electronic health records to support service providers, use of electronic laboratory ordering and prescribing, and development of a patient portal. Data from a sample of electronic patient records from each site were analyzed to assess changes in utilization of comprehensive care (prevention screening, support service utilization), engagement in primary HIV medical care (receipt of services and use of antiretroviral therapy), and viral suppression. W...
The usefulness of a diagnostic method combining high-resolution CT findings and serum markers for cytomegalovirus pneumonia and pneumocystis pneumonia in non-AIDS patients.
CONCLUSION: The combined use of HRCT findings and serum markers is useful for the diagnosis of CMVP and PCP in non-AIDS patients. The typical HRCT findings for the differential diagnosis included extensive GGA with mosaic pattern in PCP and nodules, nodules with or without the tree-in-bud pattern, and the halo sign in CMVP. PMID: 25031277 [PubMed - as supplied by publisher] (Source: Acta Radiologica)
Microdevices for examining immunological responses of single cells to HIV.
Authors: Choi J, Jeong Y, Lee KH Abstract More than 60 million people in the world have been diagnosed with human immunodeficiency virus (HIV) infections since the virus was recognized as the causative agent of acquired immunodeficiency syndrome (AIDS) in the 1980s. Even though more than half of the infected patients have died, effective disease treatment and prevention measures have not been established. Antiretroviral therapy is the only proven HIV treatment which sustains suppression of patient viremia. Current routine approaches to treat HIV infections are targeted at developing vaccines that will induce humoral or cell memory immune responses. However, developing an effective vaccine has been challenging because the HIV mutates rapidly, which allows the virus to evade immune s...
Sierra Leone: Treating Children with Malaria
Pediatrician Leo Ho worked in the intensive care unit of the MSF-run Gondama Hospital in the Bo region of Sierra Leone in 2007. During his assignment, Dr. Ho was continually treating the most severe malaria cases: children brought to the hospital who had already fallen into a coma; those who were severely malnourished; or also suffering from tuberculosis or HIV/AIDS. ?We were just trying to keep them alive,? says Dr. Ho. (Source: MSF News)
Americans With AIDS Should Be Screened for CryptococcusAmericans With AIDS Should Be Screened for Cryptococcus
A CDC study has suggested that 2.9% of Americans with advanced AIDS were positive for cryptococcal antigen between 1986 and 2012; screening could decrease mortality and costs. Medscape Medical News (Source: Medscape Medical News Headlines)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Sexual Orientation and Health Among U.S. Adults: National Health Interview Survey, 2013
NHIS is an annual multipurpose health survey conducted continuously throughout the year. Analyses were based on data collected in 2013 from 34,557 adults aged 18 and over. Sampling weights were used to produce national estimates that are representative of the civilian non-institutionalized U.S. adult population. Differences in health-related behaviors, health status, health care service utilization, and health care access by sexual orientation were examined for adults aged 18?64, and separately for men and women. (Source: CDC HIV/AIDS Prevention)
DRC: Renewed Violence in Baraka, South Kivu
Renewed fighting erupted in the beginning of November in Baraka, South Kivu Province, in northeastern Democratic Republic of Congo. In Baraka, MSF is supporting a general hospital and treating tuberculosis, HIV/AIDS, and cholera, as well as running a nutrition project and providing reproductive health care. As MSF head of mission for South Kivu, Goedele Van Bavel, explains in this audio slide show, MSF is currently balancing whether to evacuate its operations in light of the recent developments. (Source: MSF News)
Africa: Investment Needed for Health and Human Rights of People Who Inject Drugs
[Key Correspondents]People who inject drugs remain one of the highest-risk groups for contracting HIV, but infringements of their human rights around the world threatens to derail progress on ending AIDS. (Source: AllAfrica News: Health and Medicine)
Social Determinants of Health among Adults with Diagnosed HIV Infection in 20 States, the District of Columbia, and Puerto Rico, 2010
The report will focus on census tract-level social determinants of health (SDH) among adults with HIV infection diagnosed in 2010 in 20 U.S. states, the District of Columbia, and Puerto Rico. The report will present national HIV surveillance data and SDH in various stratifications by race/ethnicity, sex, age, and transmission category. The SDH variables examined are: % of the population living below federal poverty, % of population with less than high school diploma, median household income, and % of population unemployed. (Source: CDC HIV/AIDS Prevention)
HIV/AIDS Data through December 2011: Provided for the Ryan White HIV/AIDS Treatment Extension Act of 2009, for Fiscal Year 2013
The report describes how HIV surveillance data are used for funding Ryan White HIV/AIDS programs. (Source: CDC HIV/AIDS Prevention)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Africa: Could HIV Self-Testing Be a Game Changer in Africa?
[AlertNet]London -In Africa, where fewer than half the people know their HIV status, HIV self-testing is being explored as a way of encouraging more individuals, particularly in high risk groups, to know their status as a first step to seeking treatment, an AIDS charity said on Monday. (Source: AllAfrica News: Health and Medicine)
Kenya: Govt, NGOs Partnership Supports Fight Against HIV, Disease
[CAJ News]Nairobi -GOVERNMENT welcomed its partnership with the Global Fund to Fight AIDS, Tuberculosis and Malaria and Kenya Red Cross. (Source: AllAfrica News: HIV-Aids and STDs)
Uganda: Ruling Against LGBT Activists Sets Dangerous Precedent
[HRW]Nairobi -The decision of the Ugandan High Court published on July 9, 2014, endorsing the government closure of a lesbian, gay, bisexual and transgender (LGBT) rights workshop violates the right to freedom of assembly, Human Rights Watch said today. (Source: AllAfrica News: HIV-Aids and STDs)
Namibia: Ministry Scales Up Circumcision Drive
[New Era]The Zambezi Region has the highest HIV prevalence rate in the country, compounded by male residents' reluctance to get circumcised. (Source: AllAfrica News: HIV-Aids and STDs)
HIV: 'the WHO is perpetuating gay stereotypes'
The World Health Organisation has recommended that all gay men take antiretroviral drugs to stop the spread of HIV, but surely education - not more drugs - is the answer (Source: Telegraph Health)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Zambia: Sex Industry Demand for Unsafe Sex Hampers Fight Against HIV
[Key Correspondents]A Zambian sex worker living with HIV says efforts to reduce new HIV infections are being hampered by demand for unprotected sex, which comes at a higher price. (Source: AllAfrica News: HIV-Aids and STDs)
Kenya: Community and Clergy Urged to Support Needle Exchange Services
[AlertNet]Community and religious groups are failing to support needle exchange services for drug users in Kenya, despite government efforts to provide clean needles and reduce the spread of HIV. (Source: AllAfrica News: HIV-Aids and STDs)
Serum-Based Assay Accurately Detects Single Nucleotide Polymorphisms of IL28B and SOCS3 in HIV/Hepatitis C Virus-Coinfected Subjects
AIDS Research and Human Retroviruses , Vol. 0, No. 0. (Source: AIDS Research and Human Retroviruses)
Highlights from this issue
Having just returned from the Centers for Disease Control and American Sexually Transmitted Diseases Association (ASTDA) conference in Atlanta, I&rsquo;m struck by the speed of technological change in how we collect, handle and use data. Many presentations addressed novel means of surveillance, and indeed addressed a wider variety of potential influences on sexual health than we usually consider&mdash;for example, housing, and local crime rates. Secret diaries are no longer in the form of a the handwritten scrawl of Adrian Mole aged 13&mdash;we now ask research subjects and to entrust us with online records of their sexual life. In this issue Stalgaitis and Glick1 report a systematic review of the use of web-based diaries in sexual risk behaviour research, reflecting on their use, methodol...
How important is confidentiality in sexual health clinics? A survey of patients across 51 clinics in England
Introduction Confidentiality has been the bedrock of sexually transmitted infection (STI) clinics in the UK since the Venereal Diseases Act 1917,1 which has been updated with each reorganisation of the NHS within England.2 Anyone attending a STI clinic is ensured confidentiality and anonymity beyond that routinely provided within the NHS by having separate registration systems, and separate case notes or electronic patient records, from other health service records. Investigations are ordered using a clinic number, not the person's name, and there is no routine communication with general practitioners (GP). Patients are also under no obligation to provide their real name. This additional confidentiality is very important to some. Of school attendees aged 13&ndash;14&nbsp;years, 56.3% rated...<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
HPTN 035 phase II/IIb randomised safety and effectiveness study of the vaginal microbicides BufferGel and 0.5% PRO 2000 for the prevention of sexually transmitted infections in women
Conclusions The incidence of STIs was high during HIV Prevention Trials Network 035 despite provision of free condoms and comprehensive risk-reduction counselling, highlighting the need for effective STI prevention programmes in this population. Unfortunately, candidate microbicides BufferGel and PRO2000 had no protective effect against gonorrhoea, chlamydia or trichomoniasis. Trial registration number NCT00074425. (Source: Sexually Transmitted Infections)
The use of web-based diaries in sexual risk behaviour research: a systematic review
Conclusions Web-based diaries are an effective means of studying sexual risk behaviour. More uniform reporting and further research on the extent of reactivity are needed. (Source: Sexually Transmitted Infections)
Systematic review and meta-analysis of HIV prevalence among men in militaries in low income and middle income countries
Conclusions Our data reveals that across the different settings, the burden of HIV among militaries may be higher or lower than the civilian male populations. In this study, male military populations in sub-Saharan Africa, low-income countries and longer-serving men have significantly higher HIV prevalence. Given the national security implications of the increased burden of HIV, interventions targeting military personnel in these populations should be scaled up where appropriate. (Source: Sexually Transmitted Infections)
A peer-led, community-based rapid HIV testing intervention among untested men who have sex with men in China: an operational model for expansion of HIV testing and linkage to care
Conclusions Trained peers providing rapid HIV testing with social support and case management through the early period following diagnosis can efficiently expand HIV testing and improve linkage to care among MSM in China. (Source: Sexually Transmitted Infections)
Reliance on condoms for contraceptive protection among HIV care and treatment clients: a mixed methods study on contraceptive choice and motivation within a generalised epidemic
Conclusions Fears of reinfection prevailed over consideration of pregnancy risk. Given current evidence on reinfection, HCTx services must move beyond a narrow focus on condom promotion, particularly for those in seroconcordant relationships, and consider diverse strategies to meet reproductive needs. (Source: Sexually Transmitted Infections)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Men seeking sex online practise riskier sexual behaviours than men frequenting brothels: survey findings from Singapore
Conclusions Men seeking sex online should receive sexually transmitted infection (STI)/HIV prevention interventions that deal with the factors associated with condom use. (Source: Sexually Transmitted Infections)
Decisions, decisions: the importance of condom use decision making among HIV sero-discordant couples in a prospective cohort study in Uganda
Conclusions Couples who disagreed on decision making, or agreed that one partner decides alone, had significantly lower odds of reporting condom use compared with couples who decided together. HIV counselling interventions that encourage joint sexual decision making may improve condom use within this population. (Source: Sexually Transmitted Infections)
Identifying recently acquired HIV infections among newly diagnosed men who have sex with men attending STI clinics in The Netherlands
Conclusions The proportion of RIs was comparable to studies in similar settings in Europe. Implementation of the RITA for routine surveillance in The Netherlands to assess trends in RIs over time, to study the infections in other groups and to inform public health actions, is being planned. (Source: Sexually Transmitted Infections)
Suboptimal plasma HIV-1 RNA suppression and adherence among sex workers who use illicit drugs in a Canadian setting: an observational cohort study
Conclusions Evidence-based interventions to improve adherence to ART among SW-DU are urgently needed to help produce the maximum HIV treatment and prevention benefit of ART among this highly vulnerable population. (Source: Sexually Transmitted Infections)
The dual impact of antiretroviral therapy and sexual behaviour changes on HIV epidemiologic trends in Uganda: a modelling study
Conclusions HIV prevalence will rise. Even small increases in partner turnover rates will lead to an additional substantial increase in HIV prevalence. Policy makers are urged to continue HIV prevention activities, including promoting sex education, and to be prepared for a higher than previously suggested number of HIV infected people in need of treatment. (Source: Sexually Transmitted Infections)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
HIV treatment cascade among transgender women in a San Francisco respondent driven sampling study
Conclusions We observed a high prevalence of HIV in our population-based estimates of transwomen in San Francisco, coupled with modest ART use and low virological suppression rates, indicating high potential for forward transmission. Poor HIV treatment outcomes were consistently associated with housing instability. These data suggest that multi-level efforts, including efforts to address housing insecurity, are urgently needed to ameliorate disparities in HIV clinical outcomes among transwomen and reduce secondary HIV transmission to their partners. (Source: Sexually Transmitted Infections)
Cerebral microsporidiosis manifesting as progressive multifocal leukoencephalopathy in an HIV-infected individual - a case report
This report underscores the need for physicians to consider microsporidiosis (potentially affecting the brain) when no other etiology is established both in HIV, non-HIV immunosuppressed patients and in immunocompetent individuals. (Source: AIDS Research and Therapy)
Preparation of ?-D glucan nanoparticles and its antifungal activity.
Authors: Anusuya S, Sathiyabama M Abstract This work demonstrates the preparation of ?-D-glucan (isolated from the cell wall of Pythium aphanidermatum) nanoparticles through the addition of 2% (w/v) sodium hydroxide to ?-D glucan solution with constant stirring at 90° C. Addition of sodium tripolyphosphate (TPP) aids the stable formation of nanoparticles. Fourier transform infrared (FTIR) spectroscopy confirmed phosphoric groups of TPP linked with OH group of ?-D-glucan in the nanoparticles. The formation of nanoparticles was observed by the peak at 386nm using UV- visible spectroscopy. The average size of nanoparticle as determined by Zetasizer was about 60nm, while the zeta potential was negative. Scanning electron microscope image showed spherical, smooth and almost homogeno...
Contributions of cell growth and biochemical reactions to nongenetic variability of cells.
This article offers a widely-applicable theory on the influence of biochemical reactions and cellular growth on the phenotypic variability of growing, isogenic cells. The theory aids the design and interpretation of experiments involving single-molecule counting or real-time imaging of fluorescent reporter constructs. PMID: 25028872 [PubMed - in process] (Source: Biophysical Journal)
The perceived benefit of the disability grant for persons living with HIV in an informal settlement community in the Western Cape, South Africa
For persons living with HIV (PLWH) in limited socioeconomic circumstances in South Africa, social grants for disability have contributed significantly to alleviate poverty, yet there is a risk that recipients may lose these grants once they are clinically stable on antiretroviral therapy (ART). Our qualitative research explored perceptions and experiences of PLWH on ART concerning the social grant for disability and its contribution to health. Three focus groups were conducted with 15 purposively selected participants who attended a primary care clinic in the Western Cape. (Source: Journal of the Association of Nurses in AIDS Care)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Reactions: AIDS 'Cures,' Sharing Therapy Notes, Examining the Physical Exam
Letters to the editor and online comments. (Source: NYT Health)
Prevalence of HIV-1 Transmitted Drug Resistance in Liberia
AIDS Research and Human Retroviruses , Vol. 0, No. 0. (Source: AIDS Research and Human Retroviruses)
Nigeria: Nigeria Has Largest Aids Project in the World - USAID Director
[Daily Trust]Mission Director, of the United States Agency for International Development (USAID), Michael Harvey has said that Nigeria has the largest AIDs project of the agency, in the world. He said so today at the End of Project Dissemination of the Community Based Support (CUBS) for Orphans and Vulnerable Children which took place at the Yar'Adua Centre, Abuja. (Source: AllAfrica News: HIV-Aids and STDs)
Yerkes team receives HIV grant
AmfAR, the Foundation for AIDS Research gave $180,000 to a research team at Yerkes National Primate Research Center. The group, led by Dr. Guido Silvestri on the campus of Emory University, will study non-human primates infected with simian immunodeficiency virus (SIV), which closely mimics HIV in humans. They are analyzing SIV-infected non-human primates in hopes of learning how ?the Berlin patient,? an HIV-positive man with leukemia, was cured of HIV six years ago by receiving a stem cell? (Source: bizjournals.com Health Care:Biotechnology headlines)
Discharge, TSS, and E.coli Response to Rainfall Events in Urban, Suburban, and Rural Watersheds
Environ. Sci.: Processes Impacts, 2014, Accepted ManuscriptDOI: 10.1039/C4EM00327F, PaperHuajin Chen, Heejun ChangUnderstanding dominant processes influencing microorganism responses to storm events aids in the development of effective management controls on pathogen contamination in surface water so that they are suitable for water...The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - J. Environ. Monit. latest articles)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Traumatic revictimization of men who have sex with men living with HIV/AIDS - Pantalone DW, Horvath KJ, Hart TA, Valentine SE, Kaysen DL.
Abuse in childhood has been established as a predictor of adult abuse, with the strongest associations found between childhood sexual abuse (CSA) and adult sexual victimization. Revictimization has been demonstrated among women, and there is a growing lite... (Source: SafetyLit: All (Unduplicated))
Nigeria: BSN Joins War Against HIV/Aids
[Independent]Lagos -The General Secretary, Bible Society of Nigeria, Rev. Dare Ajiboye, has said that part of the primary duties of the organisation are Bible translation and distribution to Nigerians in an affordable manner. (Source: AllAfrica News: HIV-Aids and STDs)
Kenya: Can the HIV Prevention Pill Work in Kenya?
[The Star]In the 30 years since Aids was identified as a disease, nearly 30 million people have died and another 35 million are currently infected with HIV worldwide. (Source: AllAfrica News: Health and Medicine)
Malawi: Only 30 000 Children Living With HIV Receive Care and Treatment
[Malawi News Agency]Salima -Only 30 000 out of the 180 000 children living with HIV in the country are receiving care and treatment, head of Baylor College of Medicine HIV program Dr. Saeed Ahmed has disclosed. (Source: AllAfrica News: HIV-Aids and STDs)
Kenya: Sex Workers At High Risk of HIV Due to Poor Funding.
[The Star]The government is being urged to put more funding on HIV projects especially those targeting sex workers. Activist Peninah Mwangi says donor funding on these projects has reduced significantly and the government should allocate money to buy condoms, testing kits and create awareness. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
HRSA: Clarifications Regarding the Ryan White HIV/AIDS Program and Reconciliation of Advanced Premium Tax Credits Under the Affordable Care Act; Request for Comment
HRSA's HIV/AIDS Bureau is seeking comments on a recently released clarification to a policy which requires Ryan White HIV/AIDS Program grantees and subgrantees that use program funds to purchase health insurance through the Marketplace to pursue any excess premium tax credit a client receives from the IRS upon submission of the client's tax return. (Source: Federal Register updates via the Rural Assistance Center)
Nanoparticle-Spiked Drink Aids Intestinal Imaging In Mice
Micellar naphthalocyanine dye particles let researchers use photoacoustic imaging to spy on tough-to-see sections of the gut (Source: NanoFocus)
Kenya: Over 200 New Cases of HIV Victims
[The Star]There are 214, 000 new cases for sex workers who are HIV positive. Sex workers rights activist Peninah Mwangi says both the national and county governments must both come up with specific programmes for supporting sex workers especially in creating awareness and provision of free condoms (Source: AllAfrica News: HIV-Aids and STDs)
Multiple Macroenzymes in a Patient With AIDS: Diagnosis Using Ultrafiltration.
CONCLUSIONS: A previous report shows that in cases of excess immunoglobulin, PEG coprecipitates monomeric enzymes along with serum globulins, causing false-positive reporting of macroenzymes. This may explain the discrepancy between PEG and UF results in the presence of hypergammaglobulinemia, making UF a better method of detection in these circumstances. PMID: 25015871 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Cuomo's Plan for HIV Drug Draws Critics
Truvada, a medication that can help prevent HIV in healthy individuals, is gaining favor with government officials, including New York Gov. Andrew Cuomo, but some AIDS activists are opposed to its use. (Source: WSJ.com: Health)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Cross-sectional study of the characteristics, healthcare usage, morbidity and mortality of injecting drug users attending an inner city emergency department
Conclusions Our study characterises the emergency presentations of active IDUs. We describe considerable acute and chronic medical consequences and high healthcare utilisation associated with IDU. This study is of particular relevance to any institution that provides acute medical care to this group of patients. (Source: Emergency Medicine Journal)
Elevated Intraindividual Variability in methamphetamine dependence is associated With poorer everyday functioning
(Source: Psychiatry Research)
Associated changes in the transcription levels of IL-17A and tight junction-associated genes in the duodenal mucosa of rhesus macaques repeatedly exposed to simian/human immunodeficiency virus.
CONCLUSIONS: Acute SHIV, and by extension HIV infection could affect the expression of TJ-associated genes, probably through IL-17A and other immune alterations. PMID: 25034324 [PubMed - as supplied by publisher] (Source: Experimental and Molecular Pathology)
A Universal Decision Support System: Addressing the Decision Making Needs of Patients, Families, and Clinicians in the Setting of Critical Illness.
Authors: Cox CE, White DB, Abernethy AP Abstract In the setting of a complex critical illness, preference-sensitive decision making-choosing between two or more reasonable treatment options-can be difficult for patients, families, and clinicians alike. A common challenge to making high-quality decisions in this setting is a lack of critical information access and sharing among participants. Decision aids-brochures, web applications, and videos-are a major focus of current research because mounting evidence suggests they can improve decision making quality and enhance collaborative shared decision making. However, many decision aids have important limitations including a relatively narrow capacity for personalization, an inability to gather and generate clinical data, a focus on onl...
Methodology Review: Using Dual-Energy X-ray Absorptiometry (DXA) for the Assessment of Body Composition in Athletes and Active People.
Authors: Nana A, Slater GJ, Stewart AD, Burke LM Abstract Dual energy X-ray absorptiometry (DXA) is rapidly becoming more accessible and popular as a technique to monitor body composition, especially in athletic populations. Although studies in sedentary populations have investigated the validity of DXA assessment of body composition, few studies have examined the issues of reliability in athletic populations and most studies which involve DXA measurements of body composition provide little information on their scanning protocols. This review presents a summary of the sources of error and variability in the measurement of body composition by DXA, and develops a theoretical model of best practice to standardise the conduct and analysis of a DXA scan. Components of this protocol incl...<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Signaling of Chloroquine-induced stress in the yeast Saccharomyces cerevisiae requires the Hog1 and Slt2 MAPK Pathways.
Authors: Baranwal S, Azad GK, Singh V, Tomar RS Abstract Chloroquine (CQ) is under clinical use for several decades yet, little is known about CQ sensing and signaling mechanisms or about their impact on various biological pathways. We employed budding yeast Saccharomyces cerevisiae as a model organism to study the pathways targeted by CQ. Our screening with yeast mutants revealed that it targets histone proteins and histone deacetylases (HDACs). Here, we also describe the novel role of mitogen-activated protein kinase Hog1 and Slt2 that aids in survival in the presence of CQ. Cells deficient in Hog1 or Slt2 are found to be CQ hypersensitive and both proteins were phosphorylated in response to CQ exposure. CQ-activated Hog1p is translocated to nucleus and facilitates the expression...
The Prevalence and Incidence of Epiretinal Membranes in Eyes With Inactive Extramacular CMV Retinitis [Retina]
Conclusions. A history of extramacular CMV retinitis is associated with increased prevalence and incidence of ERM formation compared to what is seen in eyes without ocular opportunistic infections in AIDS patients. (Source: Investigative Ophthalmology)
Relationships between familial HIV/AIDS and symptoms of anxiety and depression: the mediating effect of bullying victimization in a prospective sample of South African children and adolescents - Boyes ME, Cluver LD.
South African children and adolescents living in HIV/AIDS-affected families are at elevated risk of both symptoms of anxiety and depressive symptoms. Poverty and HIV/AIDS-related stigma are additional risk factors for these negative mental health outcomes.... (Source: SafetyLit: All (Unduplicated))
Traumatic revictimization of men who have sex with men living with HIV/AIDS - Pantalone DW, Horvath KJ, Hart TA, Valentine SE, Kaysen DL.
Abuse in childhood has been established as a predictor of adult abuse, with the strongest associations found between childhood sexual abuse (CSA) and adult sexual victimization. Revictimization has been demonstrated among women, and there is a growing lite... (Source: SafetyLit: All (Unduplicated))
Malawi: Empower Women Economically to Eradicate Gender Based Violence and HIV/Aids
[Malawi News Agency]Blantyre -The World University Service of Canada (WUSC) said empowering women economically can help to reduce gender based violence and minimize further spread of HIV and Aids as women would meet their daily needs to reduce their vulnerability. (Source: AllAfrica News: Health and Medicine)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
The effects of opioids on HIV reactivation in latently-infected T-lymphoblasts.
CONCLUSIONS: Opioids reactivate HIV in vitro but at concentrations that are far above the plasma levels of analgesic regimes or drug concentrations found in IDUs. HIV reactivation was mediated by effects unrelated to opioid-receptor activation and was tightly linked to the cytotoxic activity of the substances at millimolar concentrations, suggesting that opioid-mediated reactivation of HIV was due to accompanying effects of cellular necrosis such as activation of reactive oxygen species and NF-?B. PMID: 25013451 [PubMed] (Source: AIDS Research and Therapy)
German cohort of HCV mono-infected and HCV/HIV co-infected patients reveals relative under-treatment of co-infected patients.
CONCLUSION: Overall, treatment was only initiated in half of the patients of the entire cohort and in an even smaller proportion of HCV/HIV co-infected patients despite comparable outcome (SVR) and similar baseline characteristics. In the light of newer treatment options, greater efforts to remove the barriers to treatment that still exist for a great proportion of patients especially with HIV/HCV co-infection have to be undertaken. PMID: 25006340 [PubMed] (Source: AIDS Research and Therapy)
Mononuclear Phagocyte Accumulation in Visceral Tissue in HIV Encephalitis: Evidence for Increased Monocyte/Macrophage Trafficking and Altered Differentiation.
Authors: Fischer T, Wyatt CM, D'Agati VD, Croul S, McCourt L, Morgello S, Rappaport J Abstract The invasion of circulating monocytes/macrophages (M?)s from the peripheral blood into the central nervous system (CNS) appears to play an important role in the pathogenesis of HIV dementia (HIV-D), the most severe form of HIV-associated neurocognitive disorders (HAND), often confirmed histologically as HIV encephalitis (HIVE). In order to determine if trafficking of monocytes/M?s is exclusive to the CNS or if it also occurs in organs outside of the brain, we have focused our investigation on visceral tissues of patients with HIVE. Liver, lymph node, spleen, and kidney autopsy tissues from the same HIVE cases investigated in earlier studies were examined by immunohistochemistry for the ...
The Antiretroviral Therapy Cohort Collaboration (ART-CC). Durability of first ART regimen and risk factors for modification, interruption or death in HIV-positive patients starting ART in Europe and North America 2002?2009: Erratum
No abstract available (Source: AIDS)
Genome-wide analysis of histone modifications in latently HIV-1 infected T cells
Conclusion:The transcriptional regulation by epigenetic memory should play a key role in the evolution and maintenance of HIV-1 latency accompanied by modulation of signalling molecules in the host cells. (Source: AIDS)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
HIV 'cure' won't work until virus eliminated from body
A baby in Mississippi reported free of HIV has relapsed &ndash; showing that even traces of the virus can rebound (Source: New Scientist - HIV and AIDS)
Interventions to improve hearing aid use in adult auditory rehabilitation.
CONCLUSIONS: There is some low to very low quality evidence to support the use of self management support and complex interventions combining self management support and delivery system design in adult auditory rehabilitation. However, effect sizes are small and the range of interventions that have been tested is relatively limited. Priorities for future research should be assessment of long-term outcome a year or more after the intervention, development of a core outcome set for adult auditory rehabilitation and development of study designs and outcome measures that are powered to detect incremental effects of rehabilitative healthcare system changes over and above the provision of a hearing aid. PMID: 25019297 [PubMed - as supplied by publisher] (Source: Cochrane Database of Systemat...
WHO says 'Gay men should take AIDS drugs - even if they're not infected'
This approach is known as pre-exposure prophylaxis or PrEP and is way for at-risk groups protect themselves by taking a single pill, claims the Geneva-based organisation. (Source: the Mail online | Health)
Global Progress on HIV Threatened: WHOGlobal Progress on HIV Threatened: WHO
People most at risk for HIV infection are not getting the health services they need, the World Health Organization (WHO) warns. Medscape Medical News (Source: Medscape Medical News Headlines)
Latest HIV Cure Data Expected at AIDS 2014, More Hep C NewsLatest HIV Cure Data Expected at AIDS 2014, More Hep C News
Scientists and policy makers will gather next week at the largest global HIV meeting, where trial results for TURQUOISE-1 and PHOTO-2 will be presented. Medscape Medical News (Source: Medscape Medical News Headlines)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
No end yet in sight for scourge: Setback to Aids battle as child tests positive again
A four-year-old child who was said last year to have been cured of Aids after radical treatment with anti-viral drugs within hours of its birth has been found to be HIV positive ? shattering the hopes that the virus could be vanquished. (Source: The Independent - Science)
Doctors' hopes for radical cure are 'shattered' as a child treated for AIDS is now found to be HIV positive
A four-year-old child who was said last year to have been cured of AIDs after radical treatment with anti-viral drugs within hours of its birth has been found to be HIV positive ? shattering the hopes that the virus could be vanquished. (Source: The Independent - Science)
No end yet in sight for scourge: Setback to Aids battle as child tests positive again
A four-year-old child who was said last year to have been cured of AIDs after radical treatment with anti-viral drugs within hours of its birth has been found to be HIV positive ? shattering the hopes that the virus could be vanquished. (Source: The Independent - Science)
HIV Signs in Child Hoped to Be Cured
A Mississippi child born with the AIDS virus who scientists thought might have been cured following drug treatment has shown signs of infection again. (Source: WSJ.com: Health)
20th International AIDS Conference20th International AIDS Conference
Read clinically focused news coverage of key developments from AIDS 2014. Medscape HIV/AIDS (Source: Medscape Hiv-Aids Headlines)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
If Big Pharma Ignores Antibacterial R&D, Where Will We Get The Drugs To Treat Superbugs?
What is needed is more basic research on bacterial drug resistance. This is where the NIH can play a big role. The total 2014 NIH budget for infectious diseases is $5 billion. However, this is spread across all infectious diseases like HIV/AIDS, as well as biodefense work. Perhaps the time has come for the NIH to make understanding the mechanisms of bacterial resistance a national health priority and invest accordingly. (Source: Forbes.com Healthcare News)
Africa: TB Drug Resistance Signifies Failure
[IRIN]London -Tuberculosis control programmes are among the oldest public health campaigns (dating back 125 years) but are not nearly as successful as they should be. Despite effective drugs having been available for over 50 years, TB still kills a million people a year, making it the world's single deadliest infectious disease after AIDS. (Source: AllAfrica News: Health and Medicine)
Sex differences in benzodiazepine use in the HIV-infected population
(Source: AIDS Care)
An assessment of health-care students' attitudes toward patients with or at high risk for HIV: implications for education and cultural competency
(Source: AIDS Care)
Perceptions of barriers and facilitators to cervical cancer screening among low-income, HIV-infected women from an integrated HIV clinic
(Source: AIDS Care)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Health care students' reactions towards HIV patients: examining prejudice, emotions, attribution of blame and willingness to interact with HIV/AIDS patients
(Source: AIDS Care)
Motivational barriers to retention of at-risk young adults in HIV-prevention interventions: perceived pressure and efficacy
(Source: AIDS Care)
Lost-to-care and engaged-in-care HIV patients in Leningrad Oblast, Russian Federation: barriers and facilitators to medical visit retention
(Source: AIDS Care)
Sex differentials in the uptake of antiretroviral treatment in Zambia
(Source: AIDS Care)
Covariates of condom use in South Africa: findings from a national population-based survey in 2008
(Source: AIDS Care)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
An examination of the HIV serostatus disclosure process among Haitian immigrants in New York City
(Source: AIDS Care)
Dynamic social support networks of younger black men who have sex with men with new HIV infection
(Source: AIDS Care)
My intention was a child but I was very afraid: fertility intentions and HIV risk perceptions among HIV-serodiscordant couples experiencing pregnancy in Kenya
(Source: AIDS Care)
Alcohol use and its association with HIV risk behaviors among a cohort of patients attending HIV clinical care in Tanzania, Kenya, and Namibia
(Source: AIDS Care)
Attitudes toward, and interest in, the test-and-treat strategy for HIV prevention among Thai men who have sex with men
(Source: AIDS Care)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Associations of unprotected anal intercourse with Grindr-met partners among Grindr-using young men who have sex with men in Los Angeles
(Source: AIDS Care)
Community-based electronic data collections for HIV prevention research with black/African-American men in the rural, Southern USA
(Source: AIDS Care)
Development of an electronic medical record-based algorithm to identify patients with unknown HIV status
(Source: AIDS Care)
Tanzania: Quality ARVs Available Nationwide, Aids Body Assures
[Daily News]TANZANIA Commission for AIDS (TACAIDS) yesterday assured availability of anti-retroviral drugs (ARVs), maintaining that quality ARVs are available across the country. (Source: AllAfrica News: HIV-Aids and STDs)
WHO: People most at risk of HIV are not getting the health services they need
Failure to provide adequate HIV services for key groups ? men who have sex with men, people in prison, people who inject drugs, sex workers and transgender people ? threatens global progress on the HIV response, warns WHO. These people are most at risk of HIV infection yet are least likely to have access to HIV prevention, testing and treatment services. In many countries they are left out of national HIV plans, and discriminatory laws and policies are major barriers to access. (Source: WHO news)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Doctors devastated after HIV virus reappears in toddler believed to have been cured
As recently as March, doctors had said that the 4-year-old Mississippi girl seemed free of HIV despite not having been on AIDS drugs for about two years, which was a medical first. (Source: the Mail online | Health)
Key high-risk HIV groups threaten AIDS progress, warns the WHO
GENEVA/LONDON - Five key groups, including gay men, prostitutes and prisoners, have stubbornly high rates of HIV that are threatening progress in the global AIDS battle, the World Health Organisation (WHO) said on Friday. (Source: Reuters: Health)
Prevalence and Correlates of Cryptococcal Antigen Positivity Among AIDS Patients ? United States, 1986?2012
(Source: CDC Morbidity and Mortality Weekly Report)
Migrant children used as human pawns to spread infectious disease across America, warn netizens
(NaturalNews) America is in a de facto state of invasion, and it's an invasion that was deliberately engineered to "occupy" America with a flood of illegal immigrants known to be carriers of tuberculosis, scabies, lice, AIDS, Swine Flu and other infectious diseases, warn netizens... (Source: NaturalNews.com)
Malawi: Discrimination Makes Women Vulnerable to HIV
[Malawi News Agency]Lack of economic opportunities, low educational levels, social and political discrimination influences the vulnerability of women to HIV. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Phylogenetic Analysis of HIV Type 1 CRF02_AG in Multiple Genes in Italian and African Patients Living in Italy
AIDS Research and Human Retroviruses , Vol. 0, No. 0. (Source: AIDS Research and Human Retroviruses)
HIV 'cure' girl still has virus
Mississippi child was previously thought to have been cleared of infection by powerful doses of medication after birth Continue reading... (Source: Guardian Unlimited Science)
[Perspective] A fitness bottleneck in HIV-1 transmission
A successful infection is determined in part by how close a viral genome is to an ideal sequence. [Also see Research Article by Carlson et al.] Authors: Sarah B. Joseph, Ronald Swanstrom (Source: Science: Current Issue)
[Perspective] Persistence by proliferation?
Latently HIV-infected cells driven to proliferate may raise a further challenge for eradication strategies. [Also see Research Article by Maldarelli et al.] Authors: David Margolis, Frederic Bushman (Source: Science: Current Issue)
[Editorial] End of AIDS?Hype versus hope
Since 2001, HIV incidence has declined by 33% worldwide, and more than 9.7 million people with HIV have gained access to treatment.* The Joint United Nations Programme on HIV/AIDS launched the Getting to Zero strategy (2011?2015) that includes zero new infections, zero deaths from HIV, and zero discrimination. Aspirational statements such as ?the end of AIDS? have also prevailed. However, do such pronouncements help or hurt? Do they motivate action, or do they risk incredulity, leading to inaction? Do such aspirations epitomize hype or hope? Authors: Wafaa M. El-Sadr, Katherine Harripersaud, Ronald Bayer (Source: Science: Current Issue)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
[Special Issue News] Prevention, Papua New Guinea style
In the mountainous, remote Eastern Highlands of Papua New Guinea, people gather in makeshift cinema houses to watch videos that feature people from their communities who became infected by HIV. The stars of the videos come to viewings, too, speaking with the audience about their experiences, as well as about measures they can take to protect themselves and the effective antiretroviral treatment available if they do become infected. Made by students at the University of Goroka, the videos are in the local pidgin and attract people who are not often reached by mass media campaigns that attempt to educate the public about HIV/AIDS. (Source: Science: This Week)
[Special Issue News] Malaysia: Malaysia tries to follow Australia's path
Adeeba Kamarulzaman, a leading HIV/AIDS researcher who is the dean of the faculty of medicine at the University of Malaya, studied in Australia from the time she was in high school, and, when she returned home to Malaysia, successfully lobbied the government to import harm reduction strategies that had worked there. Although many Malaysians are afraid to confront their government, Kamarulzaman has repeatedly pushed for evidence-based reforms, regardless of the political sensitivities. As transmission has shifted primarily from drug users sharing equipment to sexual transmission, she is now advocating for prevention and treatment efforts that target some of the most highly stigmatized groups in the country, including men who have sex with men, transgenders, and sex workers. (Source: Scienc...
Perceptions of health care services and HIV-related health-seeking behavior among Uganda adolescents
(Source: AIDS Care)
Urban adolescent sexual and reproductive health in low-income and middle-income countries
One of the most important aspects of adolescent health is sexual and reproductive health (SRH). Currently, sexually transmitted infections (STIs) threaten the health of adolescents more than any other age group, and as many as 2.2 million adolescents are living with HIV. Understanding adolescents&rsquo; SRH needs and how to invest in improving their health can be best addressed by knowing more about the contexts that increase their vulnerability to poor sexual health outcomes. Recent evidence has highlighted an increasingly marginalised segment of the adolescent population&mdash;and that is the urban poor adolescent population in low and middle income countries (LMIC). Using an urban health framework, this paper examines the contextual factors within an urban community that influence the S...
Tuning transcription of nutrient utilization genes to catabolic rate promotes growth in a gut bacterium
We report that the regulator controlling utilization of chondroitin sulfate (CS) in the mammalian gut symbiont Bacteroides thetaiotaomicron is activated by an intermediate in CS breakdown rather than CS itself. We determine that the rate?determining enzyme in CS breakdown is responsible for degrading this intermediate, and establish that the levels of the enzyme increase 100 fold whereas those of the regulator remain constant upon exposure to CS. Because enzyme and regulator compete for the intermediate, B. thetaiotaomicron tunes transcription of CS utilization genes to CS catabolic rate. This tuning results in a transient increase in CS utilization transcripts upon exposure to excess CS. Constitutive expression of the rate?determining enzyme hindered activation of CS utilization genes...<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Physicochemical property-driven optimization of diarylaniline compounds as potent HIV-1 non-nucleoside reverse transcriptase inhibitors.
Authors: Liu N, Qin B, Sun LQ, Yu F, Lu L, Jiang S, Lee KH, Xie L Abstract Using physicochemical property-driven optimization, twelve new diarylaniline compounds (DAANs) (7a-h, 11a-b and 12a-b) were designed and synthesized. Among them, compounds 12a-b not only showed high potency (EC50 0.96-4.92nM) against both wild-type and drug-resistant viral strains with the lowest fold change (FC 0.91 and 5.13), but also displayed acceptable drug-like properties based on aqueous solubility and lipophilicity (LE&gt;0.3, LLE&gt;5, LELP&lt;10). The correlations between potency and physicochemical properties of these DAAN analogues are also described. Compounds 12a-b merit further development as potent clinical trial candidates against AIDS. PMID: 25042339 [PubMed - as supplied by publisher] ...
Girl who was declared 'functionally cured' of HIV now has active virus
A girl who was seemingly cured of HIV following aggressive drug therapy just hours after her birth was recently discovered to be infected with the virus that causes AIDS after all, doctors announced Thursday. (Source: Los Angeles Times - Science)
Child Hoped to Be Cured of HIV Shows Signs of Virus
A Mississippi child born with the AIDS virus who scientists thought might have been cured following drug treatment has shown signs of infection again. (Source: WSJ.com: Health)
HIV detected in ?cured? Mississippi Baby, Creating Huge AIDS Therapy Setback
The infant was placed back on medication but the clinical trial to replicate virus suppression is still expected to proceed -- Read more on ScientificAmerican.com (Source: Scientific American - Official RSS Feed)
Mississippi Girl Thought Cured of HIV Shows Signs of Infection
After more than two years of no drug therapy, she's back on medication; development disappoints doctors, researchers Source: HealthDay Related MedlinePlus Pages: HIV/AIDS Medicines, HIV/AIDS and Pregnancy (Source: MedlinePlus Health News)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
'Mississippi Baby' Thought 'Cured' of HIV Relapses'Mississippi Baby' Thought 'Cured' of HIV Relapses
An infant who was seemingly cured of HIV now has detectable levels of the virus after 2 years without any evidence of the virus. Medscape Medical News (Source: Medscape Medical News Headlines)
OPINION: Unleashing African Young People?s Potential
Girls attend school in South Africa. Healthy, educated young people can help break the cycle of poverty. Credit: UNFPABy Adebayo FayoyinJOHANNESBURG, Jul 10 2014 (IPS) An African proverb says ?a child that we refuse to build today will end up selling the house that we may build tomorrow.? The moral of this is clear. Unless we invest in our children and young people today, they might become a threat or a burden in the future.As the international community commemorates World Population Day on July 11, Africa?s growing youth population should be recognised as a ?powerful force for change? that requires greater investment today. Judging by the current challenges confronting young people, the extent to which African countries are investing in the youth is unclear. More young people Ac...
Phylogenetic Analysis of Human Immunodeficiency Virus Type 2 Isolated from Cuban Individuals
AIDS Research and Human Retroviruses , Vol. 0, No. 0. (Source: AIDS Research and Human Retroviruses)
Helping Seniors with Low Vision Maintain Independence
Each day, approximately 10,000 Americans turn 65, and one in six adults this age and older has a vision impairment that cannot be corrected with glasses or contact lenses.[1] As part of its support for Senior Independence Month this July, the American Academy of Ophthalmology is providing older adults with low vision guidance on how to make the most of their remaining sight and keep their independence. (Source: Disabled World)
Caring for Persons with Early Childhood Trauma, PTSD, and HIV: a Curriculum for Clinicians.
Authors: Tavakkoli M, Cohen MA, Alfonso CA, Batista SM, Tiamson-Kassab ML, Meyer P Abstract Access and adherence to medical care enable persons with HIV to live longer and healthier lives. Adherence to care improves quality of life, prevents progression to AIDS, and also has significant public health implications. Early childhood trauma-induced posttraumatic stress disorder (PTSD) is one factor that has been identified as an obstacle to adherence to both risk reduction and HIV care. The authors developed a 4-h curriculum to provide clinicians with more confidence in their ability to elicit a trauma history, diagnose PTSD, and address trauma and its sequelae in persons with HIV to improve adherence to medical care, antiretroviral medications, and risk reduction. The curriculum was d...<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Prevalence and Correlates of Cryptococcal Antigen Positivity Among AIDS Patients - United States, 1986-2012.
This report describes the results of that analysis, which indicated the overall prevalence of CrAg positivity in this population to be 2.9% (95% confidence interval [CI] = 2.2%-3.7%). PMID: 25006824 [PubMed - as supplied by publisher] (Source: MMWR Morb Mortal Wkl...)
HIV Resurfaces in "Mississippi Baby" Many Presumed Cured
The AIDS virus persists even when undetected by ultrasensitive tests for more than 2 years (Source: ScienceNOW)
Fast Voltammetry of Metals at Carbon-Fiber Microelectrodes: Copper Adsorption onto Activated Carbon aids Rapid Electrochemical Analysis
Analyst, 2014, Accepted ManuscriptDOI: 10.1039/C4AN00937A, PaperPavithra Pathirathna, Srimal Samaranayake, Christopher W. Atcherley, Kate L Parent, Michael L. Heien, Shawn P McElmurry, Parastoo HashemiRapid, in situ trace metal analysis is essential for understanding many biological and environmental processes. For example, trace metals are thought to act as chemical messengers in the brain. In...The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Analyst latest articles)
Tanzania: People Living With HIV/Aids Urged to Form Economic Groups
[Daily News]CONTRACTING HIV/AIDS is never condemnation to begging and living a worthless life, as some HIV-positive individuals have proved to be highly productive people, leading lives as any other person, Tanzania Commission for AIDS (TACAIDS) Chairperson, Dr Fatma Mrisho, said. (Source: AllAfrica News: Health and Medicine)
Tanzania: Aids Law Now Appears Redundant
[Daily News]IN 2005, a national report on the prevalence of HIV/AIDS showed that by the end of 2004 it was estimated that 1.3 million Tanzanians had fallen victim to the virus, with the infection rate standing at seven per cent among the sexually active age groups. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Kenya: Urgently Set Up HIV Fund
[The Star]Civil society groups want the government to set aside money so that there are no stock outs of ARV's and testing kits in public hospitals. They say more donors continue to pull out of funding, thus posing a serious challenge in the fight against HIV. (Source: AllAfrica News: HIV-Aids and STDs)
Special Issue: The fight against HIV/AIDS
Experts weigh in on the state of the global epidemic (Source: ScienceNOW)
Despite setback, 'Mississippi Baby' represents significant breakthrough in effort to end AIDS
(Elizabeth Glaser Pediatric AIDS Foundation) In response to today's announcement that the 'Mississippi Baby,' believed to have been functionally cured of HIV, has now been found to have detectable levels of the virus, the Elizabeth Glaser Pediatric AIDS Foundation expresses disappointment in this setback but remains hopeful that the scientific breakthrough that allowed the child's HIV levels to remain undetectable for more than two years will continue to help researchers understand how to control HIV and ultimately develop a cure. (Source: EurekAlert! - Medicine and Health)
Gender Role Behaviors of High Affiliation and Low Self-Silencing Predict Better Adherence to Antiretroviral Therapy in Women with HIV
AIDS Patient Care and STDs , Vol. 0, No. 0. (Source: AIDS Patient Care and STDs)
Molecular Epidemiology and Clinical Features of Human T Cell Lymphotropic Virus Type 1 Infection in Spain
AIDS Research and Human Retroviruses , Vol. 0, No. 0. (Source: AIDS Research and Human Retroviruses)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
When do vertical programmes strengthen health systems? A comparative assessment of disease-specific interventions in India
Conclusions Disease-specific programmes in India are widely regarded as having made a substantial contribution in disease control. They can have both positive and negative effects on health systems. Certain conditions are necessary for them to have a positive influence on health systems&mdash;the programme needs to have an explicit policy to strengthen local health systems, and should also be embedded within the health system administration. (Source: Health Policy and Planning)
[Special Issue News] Australia: First, do harm reduction
Shortly after the AIDS epidemic surfaced in Australia, an aggressive effort began to prevent the spread of HIV in people who inject drugs. The harm reduction movement that evolved provided clean needles and syringes to users, as well as opiate substitutes like methadone that are not injected. A medically supervised injecting center also opened in Sydney?the first of its kind in the Southern Hemisphere?where people receive clean needles and syringes and legally use their drugs. HIV never got a serious foothold in this extremely vulnerable population, and Australia's harm reduction strategies eventually spread to nearby Indonesia and Malaysia, which initially had epidemics driven mainly by injecting drug use. (Source: Science: This Week)
Novel Agent Volasertib Doubles Responses in AMLNovel Agent Volasertib Doubles Responses in AML
Older patients with acute myeloid leukemia (AML) are not good candidates for intensive induction therapy, but an experimental agent might bolster the effectiveness of a standard treatment. Medscape Medical News (Source: Medscape Medical News Headlines)
HIV/TB Access Intern
Reports to: HIV/AIDS Policy Advisor for the Access CampaignType of position: Intern, paidTime Commitment: 20 hrs/weekDuration: 3 monthsLocation: New York City Language English (Source: MSF News)
Namibia: Eenhana VTC Trainees Promise to Deliver
[New Era]Trainees of the Eenhana Vocational Training Centre (EVTC) are not only promising to successfully complete their training but to deliver in their trade when they go into practicing their trades. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Namibia: Eenhana VTC Trainee Values HIV, Aids Awareness Session
[New Era]Trainees at the Eenhana Vocational Training Centre (EVTC) here seem to appreciate the HIV and AIDS awareness presentation that the Namibia Planned Parenthood Association (NAPPA) held at the Centre. (Source: AllAfrica News: HIV-Aids and STDs)
Zambia: Angolans Seek HIV, TB Treatment in Chavuma
[Times of Zambia]AN INFLUX of Angolans has been recorded in Chavuma in North-Western Province seeking HIV/AIDS and Tuberculosis treatment among others, Chavuma District Commissioner Lawrence Kayumba has said. (Source: AllAfrica News: HIV-Aids and STDs)
Kenya: Why Reproductive Health Care Bill Would Help Manage Population
[The Star]The Reproductive Health Care Bill has elicited mixed reactions. While some have supported it saying it would help reduce the rate of HIV infections and deal with the rising cases of teenage pregnancies, others have castigated it on grounds that it would erode children's moral behavior. (Source: AllAfrica News: HIV-Aids and STDs)
Uganda: Uganda Making Strong Strides in HIV Response - Rugunda
[Observer]The increment of HIV prevalence rate from 6.4 per cent in 2004/5 to 7.3 per cent in 2011 must have woken Uganda out of her slumber. (Source: AllAfrica News: HIV-Aids and STDs)
Nigeria: Fayemi Writes Ekiti Assembly Over More Lgas
[Independent]Governor Kayode Fayemi of Ekiti State has written to Ekiti State House of Assembly over plans by his administration to create 18 additional council areas, to be called local council development areas (LCDAs). (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Expectation of Volunteers Towards the Vaccine Efficacy of the Prime-Boost HIV Vaccine Phase III Trial During Unblinding
AIDS Research and Human Retroviruses , Vol. 0, No. 0. (Source: AIDS Research and Human Retroviruses)
Living with a symptomatic rotator cuff tear 'bad days, bad nights': a qualitative study
Conclusions: Clinicians need to appreciate and understand the intensity and shocking nature of pain that may be experienced by participants with known rotator cuff tears and understand the detrimental impact tears can have upon all areas of patient's lives. Clinicians also need to be aware of the potential emotional impact caused by cuff tears and to ensure that patients needing help for conditions such as depression are speedily identified and provided with support, explanation and appropriate treatment (Source: BMC Musculoskeletal Disorders)
Type I interferon responses in rhesus macaques prevent SIV infection and slow disease progression
Nature advance online publication 09 July 2014. doi:10.1038/nature13554 Authors: Netanya G. Sandler, Steven E. Bosinger, Jacob D. Estes, Richard T. R. Zhu, Gregory K. Tharp, Eli Boritz, Doron Levin, Sathi Wijeyesinghe, Krystelle Nganou Makamdop, Gregory Q. del Prete, Brenna J. Hill, J. Katherina Timmer, Emma Reiss, Ganit Yarden, Samuel Darko, Eduardo Contijoch, John Paul Todd, Guido Silvestri, Martha Nason, Robert B. Norgren, Brandon F. Keele, Srinivas Rao, Jerome A. Langer, Jeffrey D. Lifson, Gideon Schreiber & Daniel C. Douek Inflammation in HIV infection is predictive of non-AIDS morbidity and death, higher set point plasma virus load and virus acquisition; thus, therapeutic agents are in development to reduce its causes and consequences. However, inflammation may simultaneously co...
Two-port laparoscopic management of a giant pseudocyst complicating ventriculoperitoneal shunt
Sandesh V Parelkar, Beejal V Sanghvi, Devdas S Samala, Bhupesh A Paradkar, Shalil H Patil, Sanjay N OakJournal of Indian Association of Pediatric Surgeons 2014 19(3):181-183Insertion of a ventriculo-peritoneal (VP) shunt is the most common operative procedure for the treatment of hydrocephalus in children. Of the several causes of shunt malfunction, cerebrospinal fluid (CSF) pseudocyst is relatively uncommon. There are several modalities to treat a CSF pseudocyst. Laparotomy is required, at times, more than once. We managed a patient of CSF pseudocyst with two-port laparoscopy, by deroofing the psuedocyst and repositioning of the shunt. This minimally invasive technique avoids morbidity associated with laparotomy and aids in early recovery. (Source: Journal of Indian Association of Pediatr...
The AIDS Pandemic in Historic Perspective
Potent antiretroviral drugs (ART) have changed the nature of AIDS, a once deadly disease, into a manageable illness and offer the promise of reducing the spread of HIV. But the pandemic continues to expand and cause significant morbidity and devastation to families and nations as ART cannot be distributed worldwide to all who need the drugs to treat their infections, prevent HIV transmission, or serve as prophylaxis. Furthermore, conventional behavioral prevention efforts based on theories that individuals can be taught to modify risky behaviors if they have the knowledge to do so have been ineffective. Noting behavioral strategies targeting individuals fail to address broader social and political structures that create environments vulnerable to HIV spread, social scientists and public he...<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Validation of a Histoplasma ELISA antigenuria test in Colombian patients with AIDS for diagnosis and follow-up during therapy.
Authors: Caceres DH, Scheel CM, Tobón AM, Ahlquist Cleveland A, Restrepo A, Brandt ME, Chiller T, Gómez BL Abstract We validated an antigen capture ELISA test in Colombian persons with AIDS and proven histoplasmosis, and evaluated the correlation between antigenuria and clinical improvement during follow up. The sensitivity of the H. capsulatum ELISA was 86% and the overall specificity was 94%. The antigen test successfully monitored response to therapy. PMID: 25008902 [PubMed - as supplied by publisher] (Source: Clinical and Vaccine Immunology)
Interactions between HIV-1 and the Cell-Autonomous Innate Immune System.
Authors: Towers GJ, Noursadeghi M Abstract HIV-1 was recognized as the cause of AIDS in humans in 1984. Despite 30 years of intensive research, we are still unraveling the molecular details of the host-pathogen interactions that enable this virus to escape immune clearance and cause immunodeficiency. Here we explore a series of recent studies that consider how HIV-1 interacts with the cell-autonomous innate immune system as it navigates its way in and out of host cells. We discuss how these studies improve our knowledge of HIV-1 and host biology as well as increase our understanding of transmission, persistence, and immunodeficiency and the potential for therapeutic or prophylactic interventions. PMID: 25011104 [PubMed - as supplied by publisher] (Source: Cell Host and Microbe)
Type I interferon responses in rhesus macaques prevent SIV infection and slow disease progression
Authors: Netanya G. Sandler, Steven E. Bosinger, Jacob D. Estes, Richard T. R. Zhu, Gregory K. Tharp, Eli Boritz, Doron Levin, Sathi Wijeyesinghe, Krystelle Nganou Makamdop, Gregory Q. del Prete, Brenna J. Hill, J. Katherina Timmer, Emma Reiss, Ganit Yarden, Samuel Darko, Eduardo Contijoch, John Paul Todd, Guido Silvestri, Martha Nason, Robert B. Norgren Jr, Brandon F. Keele, Srinivas Rao, Jerome A. Langer, Jeffrey D. Lifson, Gideon Schreiber & Daniel C. Douek Inflammation in HIV infection is predictive of non-AIDS morbidity and death, higher set point plasma virus load and virus acquisition; thus, therapeutic agents are in development to reduce its causes and consequences. However, inflammation may simultaneously confer both detrimental and beneficial effects. This dichotomy is p...
Burden of Nonnucleoside Reverse Transcriptase Inhibitor Resistance in HIV-1-Infected Patients: A Systematic Review and Meta-Analysis
AIDS Research and Human Retroviruses , Vol. 0, No. 0. (Source: AIDS Research and Human Retroviruses)
The Effects of Chronic Binge Alcohol on the Genital Microenvironment of Simian Immunodeficiency Virus-Infected Female Rhesus Macaques
AIDS Research and Human Retroviruses , Vol. 0, No. 0. (Source: AIDS Research and Human Retroviruses)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Zambia: 'Let's Fight Early Marriages'
[Times of Zambia]AN INTERNATIONAL non-governmental organisation (NGO) working to lessen the devastating psychosocial impact of poverty, conflict, HIV/AIDS among children and youths has called for concerted efforts in addressing the challenges fueling early marriages and child sexual abuse in Zambia. (Source: AllAfrica News: HIV-Aids and STDs)
Liberia: Liberians Lead Immigrant With Highest HIV Diagnoses in Minnesota
[FrontPageAfrica]Minnesota -Some 301 people were newly infected with HIV in Minnesota in 2013, a 4 percent drop compared to 314 a year earlier, but a worrying trend persists among the Liberian immigrant community, according to a recent report released by Minnesota Department of Health (MDH). (Source: AllAfrica News: HIV-Aids and STDs)
Birth in bigger hospitals aids survival for pre-term babies
Premature babies born in bigger hospitals are more likely to survive than those born in smaller ones, a new UK study suggests. (Source: Nursing Times Breaking News)
Kenya: Go for ARVs, Infected Couples Told
[The Star]COUPLES living with HIV should go for Anti Retro Viral drugs, a clergyman has said. Tukiko Jakech, a pastor at Ogeng'o Seventh Day Adventist Church, said HIV-Aids is a reality that needs proper medical attention. (Source: AllAfrica News: HIV-Aids and STDs)
Kenya: The Week - Health & Fitness
[The Star]HIV rises among couples and cohabiting partners (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Kenya: Why HIV Does Not Kill Anymore
[The Star]When it comes to HIV, it is not the virus that kills you, it is everything else. Your body's immunity is weakened and a simple curable disease is what often gets you. (Source: AllAfrica News: HIV-Aids and STDs)
Decisional Capacity Among Youth with HIV: Results from the MacArthur Competence Tool for Treatment
AIDS Patient Care and STDs , Vol. 0, No. 0. (Source: AIDS Patient Care and STDs)
The prevalence of transmitted HIV drug resistance among MSM in Anhui province, China
Conclusions: In Anhui, CRF01_AE strains contributed to most of the HIV infections among MSM, and the prevalence of TDR was relatively low in this population. Further studies should be performed to evaluate the trend of TDR among MSM in Anhui and to inform first-line antiretroviral treatment. (Source: AIDS Research and Therapy)
Counting Down: HIV Prison-Based Peer Education Programs and Their Connection to Reduced Disciplinary Infractions
This study analyzed rates of disciplinary infractions among 49 female prisoners that worked in two HIV prison-based peer programs (AIDS, Counseling, and Education [ACE] and CARE [Counseling, AIDS, Resource, and Education]) as peer educators during their incarceration. These women were unlikely to jeopardize their position by engaging in unlawful or deviant behaviors. Results showed that working in programs like ACE/CARE prevented periods of maladjustment and subsequent disciplinary infractions during incarceration. (Source: International Journal of Offender Therapy and Comparative Criminology)
Comparing the effect of a decision aid plus patient navigation with usual care on colorectal cancer screening completion in vulnerable populations: study protocol for a randomized controlled trial
This study will test a combined decision aid and patient navigator intervention on screening completion in diverse populations of vulnerable primary care patients. Methods: We will conduct a multisite, randomized controlled trial with patient-level randomization. Planned enrollment is 300 patients aged 50 to 75 years at average CRC risk presenting for appointments at two primary clinics in North Carolina and New Mexico. Intervention participants will view a video decision aid immediately before the clinic visit. The 14 to 16 minute video presents information about fecal occult blood tests and colonoscopy and will be viewed on a portable computer tablet in English or Spanish. Clinic-based patient navigators are bilingual and bicultural and will provide both face-to-face and telephone-based ...<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Adult hearing loss services: Monitor launches review into choices available for patients
Around 500,000 patients over the age of 55 use these services every year. They may be able to choose between alternative providers of hearing tests, hearing aids and aftercare. This is because their local commissioners have taken out contracts with multiple providers, including some independent sector organisations as well as NHS bodies. These arrangements cover half of England and cost the NHS about £200 million a year. As a result of concerns about some adult hearing services, Monitor is now working with Action on Hearing Loss and other relevant charities to understand whether the interests of patients are well served. More ..... (Source: NHS Networks)
Decision Aids Help Patients but Still Are Not Widely Used
(Source: JNCI)
From rhetoric to reality? Putting HIV and AIDS rights talk into practice in a South African rural community.
We present a case study of the Entabeni Project in South Africa - in which a foreign-funded NGO sought to work with female health volunteers in a deep rural community to increase their access to two HIV-relevant rights: women's rights (especially gender equality) and rights to health (especially access to HIV- and AIDS-related services). Whilst the project had short-term health-related successes, it was less successful in implementing a gender empowerment agenda. The concept of women's rights had no purchase with women who had little interest in directly challenging male power, foregrounding the fight against poverty as their main preoccupation. The area's traditional chief and gatekeeper insisted the project should remain 'apolitical'. Project funders prioritised 'numbers reached' over a ...
Racial/ethnic disparities in HIV medical studies examined by researchers
Social/behavioral intervention vastly increased the number of African American and Latino individuals living with HIV/AIDS who enrolled in HIV/AIDS medical studies, a study has found. Nine out of 10 participants who were found eligible for studies decided to enroll, compared to zero participants among a control group. (Source: ScienceDaily Headlines)
Zimbabwe: Lessons for Climate Sector From HIV/Aids
[The Herald]Climate change experts will meet in Kariba on July 15 for a final review of Zimbabwe's climate change strategy before possible endorsement and adoption, as the country seeks to deliver greater efficiency in climate response.Two years since the process of compiling the National Climate Change Response Strategy (NCCRS) began; the crucial document may now be eventually released at a later date this year, hoping to straighten the existing budgetary and planning discord on adaptive and mitigatory action. (Source: AllAfrica News: Health and Medicine)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Adverse Events According to CD4 Count at the Start of ARTAdverse Events According to CD4 Count at the Start of ART
Are HIV patients who start ART with a higher CD4 count at greater risk of ART-related adverse events? AIDS (Source: Medscape Today Headlines)
Nigeria: Nigeria Is Largest Recipient of U.S Aid On HIV and Aids Prevention - Entwistle
[Vanguard]Nigeria is the largest recipient of the U.S President's Emergency Plan for Aids Relief (PEPFAR) in the world, U.S Ambassador to Nigeria, Mr James Entwistle, has said. (Source: AllAfrica News: HIV-Aids and STDs)
Southern Africa: Arasa and Partners to Host Workshop On HIV-Aids Reporting
[MISA]The AIDS and Rights Alliance for Southern Africa (ARASA) is a partnership of 73 non-governmental organisations (NGOs) working together to promote a rights-based response to HIV and TB in southern and eastern Africa through capacity strengthening and advocacy. It is the only regional organisation that is structured in the form of a partnership of country-based civil society organisations working together to promote human rights and health in the context of HIV, tuberculosis (TB) and sexual and reproductive (Source: AllAfrica News: HIV-Aids and STDs)
Nigeria: U.S. Boosts HIV/Aids Treatment With U.S.$458 Million Aid
[Independent]Abuja -The United States (US) has reiterated its support to Nigeria in the face of wanton killings by the Boko Haram insurgency, saying, "we want Nigeria to win the war against terrorism." (Source: AllAfrica News: HIV-Aids and STDs)
Tanzania: Let Us Do Away With Outdated Traditions
[Daily News]Last week there was shocking news from Kajiado, a town located not very far from the Kenya's capital, Nairobi. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Nigeria: Nigeria, Largest Recipient of U.S. Aid On HIV Prevention - Entwistle
[Premium Times]Mr. Entwistle made this known at a reception to celebrate the 238th anniversary of U.S. Independence in Abuja on Friday night. (Source: AllAfrica News: HIV-Aids and STDs)
NYU researchers tackle racial/ethnic disparities in HIV medical studies
(New York University) Study finds social/behavioral intervention vastly increased the number of African American and Latino individuals living with HIV/AIDS who enrolled in HIV/AIDS medical studies. Nine out of 10 participants who were found eligible for studies decided to enroll, compared to zero participants among a control group. (Source: EurekAlert! - Social and Behavioral Science)
Virologic outcomes of second-line antiretroviral therapy in Eastern European country of Georgia
Conclusions: The study demonstrated favourable virological outcomes of the second-line ART in Georgia. Majority of patients, including IDUs, achieved sustained virological response over 36 month period. The findings highlight the need of improving adherence. (Source: AIDS Research and Therapy)
Antiretroviral penetration into the CNS and incidence of AIDS-defining neurologic conditions
Conclusions: We estimated that initiation of a combined antiretroviral therapy regimen with a high CPE score increases the risk of HIV dementia, but not of other neuroAIDS conditions. (Source: Neurology)
DEFB1 5'UTR Polymorphisms Modulate the Risk of HIV-1 Infection in Mexican Women.
Authors: Estrada-Aguirre JA, Osuna-Ramirez I, de Prado-Montes EO, Ochoa-Ramirez LA, Ramirez M, Magallon-Zazueta LG, Gonzalez-Beltran MS, Cazarez-Salazar SG, Rangel-Villalobos H, Velarde-Felix JS Abstract Immunologic and genetic factors are involved in HIV-1/AIDS pathogenesis. Defensins are key molecules in innate immunity that participate in the control and/or development of infection and disease. Using PCR-RFLPs, we determined the association between HIV-1/AIDS and human ?-defensin 1 (DEFB1) 5'UTR -52 G/A (rs1799946), -44 C/G (rs1800972), and -20 G/A (rs11362) polymorphisms in three groups of women from the state of Sinaloa, located in the Northwest region of Mexico: i) sex-workers; ii) healthy blood donors; and iii) HIV-1 patients. The -52GG genotype was more frequent in blood d...<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Find the best <a href="http://www.thejanuarysales.com/">Christmas Sales</a>, <a href="http://www.thejanuarysales.com/">Boxing Day Sales</a> and <a href="http://www.thejanuarysales.com/">January Sales</a> <a href="http://www.thejanuarysales.com/">here</a>.</p></div>
Elevated postinjury thrombospondin 1-CD47 triggering aids differentiation of patients' defective inflammatory CD1a+dendritic cells.
Authors: Bandyopadhyay G, Bandyopadhyay S, Bankey PE, Miller-Graziano CL Abstract A subset of Pts develops dysfunctional MO to inflammatory DC differentiation and immunosuppression. MDDC, a newly described DC subset, is pivotal in initiating antibacterial responses. Endogenous proteins are known to alter MO to MDDC differentiation. In particular, trauma-elevated TSP-1, a protein that is known to affect MO functions, could trigger MDDC differentiation defects. We hypothesized that TSP-1-deranged differentiation of inflammatory CD1a(+)MDDC would negatively alter activation of immune functions, thereby increasing the risk of postinjury infections. Post-trauma increased TSP-1 levels in patients' plasma and MO correlated with two distinct MDDC differentiation dysfunctions: the previousl...
Viral pathogenesis: Macaque model for AIDS
This study now shows that HIV-1 adapts to replicate efficiently and cause AIDS in pig-tailed macaques. The animals were inoculated with HIV-1 and treated (Source: Nature Reviews Microbiology)
The Uncertain Future of Male Masturbation
In the not too distant past, male masturbatory aids were limited, but technological advancements are dramatically changing the masturbation experience. However, we don't know if these will prove ultimately harmful to romantic relationships.read more (Source: Psychology Today Sex Center)
Malawi: Unsafe Sex Irks HIV/Aids Fighters
[Malawi News Agency]Lilongwe -The Principal Secretary in the Department of Nutrition and HIV/Aids in the Office of the President and Cabinet, Edith Mkawa has faulted the mechanisms utilized to dispatch messages of HIV/Aids in early 1990s saying it contributed to the increased transmission of the virus. (Source: AllAfrica News: Health and Medicine)

 

 


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